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Inhalation Toxicology
International Forum for Respiratory Research
Volume 2, 1990 - Issue 1
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Research Article

Nitric Oxide and Nitrogen Dioxide as Inducers of Acute Pulmonary Injury when Inhaled at Relatively High Concentrations for Brief Periods

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Pages 53-67 | Received 11 Apr 1989, Accepted 21 Jun 1989, Published online: 27 Sep 2008

References

  • Committee on Medical and Biological Effects of Environmental Pollutants. Nitrous Oxides. National Academy of Sciences., Washington, D.C. 1977; 239
  • Cross C. E., Parsons G. H., Gorin A. B., Last J. A. pulmonary edema: Emphasis on physiological and toxicological considerations. Mechanisms in Respiratory Toxicology, H. Witschi, P. Nettesheim. CRC Press, Boca Raton, Ha 1982; vol. 1: 219–246
  • Evans M. I., Freeman G. Morphologic and pathologic effects of NO2 in rat lung. In. Nitrogen Oxides and Their Effects on Health, S. D. Lee. Ann Arbor Science Press., Ann Arbor, Mich. 1980; 243–266
  • Evans M. J., Carbral-Anderson L. G., Freeman G. Effects of NO, on the lungs of aging rats. I. Morphology. Exp. Mol. Pathol. 1977; 27: 353–365
  • Freeman G., Haydon C. B. Emphysema after low-level exposure to NO. Arch. Environ. Health 1964; 8: 125–128
  • Creenbaum R., Bay I., Hargreaves M. D., Kain M. L., Kelman G. R., Nunn J. F., Prys-Roberts C., Siebold K. Effects of higher oxides of nitrogen on the anesthetized dog. Br. J. Anaesth. 1967; 39: 393–404
  • Holt P. G., Finlay-Jones L. M., Keast D., Papadimtrou J. M. Immunologic function in mice chronically exposed to nitrogen oxides (NOx). Environ. Res. 1979; 19: 154–162
  • Hugod C. Ultrastructural changes of the rabbit lung after 5 ppm nitric oxide exposure. Arch. Environ. Health 1979a; Jan./Feb.: 12–17
  • Hugod C. Effect of exposure of 43 ppm nitric oxide and 3.6 ppm nitrogen dioxide on rabbit lung. Int. Arch. Occup. Environ. Health 1979b; 42: 159–167
  • Kon K., Maeda N., Shiga T. Effect of nitric oxide on the oxygen transport of human erythrocytes. J. Toxicol. Environ. Health 1977; 2: 1109–1113
  • Kradin R. L., Zhu Y., Hales C. A., Bianco C., Calvin R. B. Response of pulmonary macrophages to hyperoxic pulmonary injury: Acquisition of surface fibronectin and fibrin/ogen and enhanced expression of a fibronectin receptor. Am. J. Pathol. 1986; 125: 39–357
  • Lehnert B. E., Wilson J. S., Stavert D. M. Early lung changes following acute exposures to relatively high concentrations of nitrogen dioxide. Toxicologist 1987; 745
  • Maeda N., Imaizumi K., Kon K., Shiga T. A kinetic study on functional impairment of nitric oxide-exposed rat erythrocytes. Environ. Health Perspect. 1987; 73: 171–177
  • Oda H., Kusumoto S., Nakajima T. Nitrosyl-hemoglobin formation in the blood of animals exposed to nitric oxide. Arch. Environ. Health 1975; 30: 453–456
  • Pflesser G. The significance of nitric oxide poisoning by nitrous gases. Arch. Exp. Pathol. Pharrnacol. 1935; 179: 545–557
  • Ripple G., Mundie T., Stavert D. M., Lehnert B. E. Kinetics of methemoglobin formation and elimination as a function of inhaled nitric oxide concentration and minute ventilation. Toxicologist 1989; 9: 745
  • Rombout P. J.A., Dorman J. A. M. A., Marra M., van Esch G. J. Influence of exposure regimen on nitrogen dioxide-induced morphological changes in the rat lung. Environ. Res. 1986; 41: 466–480
  • Shiel F. O.M. Morbid anatomical changes in the lungs of dogs after inhalation of higher oxides of nitrogen during anaesthesia. Br. J. Anaesth. 1967; 39: 413–424
  • Smith R. P. Toxic responses of the blood. Casarett and Doull's Toxicology, C. D. Klaason, M. O. Amdur, J. Doull. Macmillan., New York 1986; 223–244
  • Snedecor G. W., Cochran W. G. The comparison of two samples. Statistical Methods. Iowa State University Press, Ames, Iowa 1969; 91–119
  • Stavert D. M., Lehnert B. E. Potentiation of the expression of nitrogen dioxide-induced lung injury by postexposure exercise. Environ. Res. 1989; 48: 87–99
  • Stavert D. M., Archuleta D. C., Holland L. M., Lehnert B. E. Nitrogen dioxide exposure and development of pulmonary emphysema. J. Toxicol. Environ. Health 1986; 17: 249–267
  • Stokinger H. E., Coffin D. L. Biologic effects of air pollutants. Air Pollution, vol. 1, Pollution and its Effects, A. D. Stern. Academic Press, New York 1968; 445–596
  • Toothill C. The chemistry of the in vivo reaction between hemoglobin and various oxides of nitrogen. Br. J. Anaesth. 1967; 39: 405–412
  • Wagner H. M. Absorption von NO und NO2 in MIK-und-MAK-konzentrationen bei der inhalation. Staub Reinhalt. Luft. 1970; 30: 380–381
  • Warnock M. L. Reactions of the lung to environment injuries. Environmental Pathology: An Evolving Field, R. B. Hill, J. A. Tenian. Alan R. Liss., New York 1982; 155–199
  • Wilson J. S., Stavert D. M., Archuleta R. F., Lehnert B. E. A novel inhalation chamber for exposure of rats to oxidant gases. Toxicologist 1987; 7203
  • Yoshida K., Kasama K. Biotransformation of nitric oxide. Environ. Health Perspect. 1987; 73: 201–206

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