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Original Article

A Chimera between Platelet-Derived Growth Factor β-Receptor and Fibroblast Growth Factor Receptor-1 Stimulates Pancreatic β-Cell. DNA Synthesis in the Presence of PDGF-BB

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Pages 93-101 | Received 08 May 1991, Accepted 26 Aug 1991, Published online: 11 Jul 2009

References

  • Abraham J. A., Whang J. L., Tumolo A., Mergia A., Friedman J., Gospodarowicz D., Fiddes J. C. Human basic fibroblast growth factor: nucleotide sequence and genomic organization. EMBO J. 1986; 5: 2523–2528
  • Bishayee S., Majumdar S., Khire J., Das M. Ligand‐induced dimerization of the platelet‐derived growth factor receptor. Monomer‐dimer interconversion occurs independent of receptor phosphorylation. J. Biol. Chem. 1989; 264: 11699–11705
  • Berggren P. O., Hallber'g A., Welsh N., Arkhammar P., Nilsson T., Welsh M. Transfection of insulin‐producing cells with a transforming c‐H‐ras oncogene stimulates phospholipase C activity. Biochem. J. 1989; 259: 701–707
  • Chirgwin J. M., Przybyla A. E., McDonald R. J., Rutter W. J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979; 18: 5294–5299
  • Claesson‐Welsh L., Eriksson A., Moren A., Severinsson L., Ek B., Östman A., Betsholtz C., Heldin C. ‐H. cDNA cloning and expression of a human platelet‐derived growth factor (PDGF) receptor specific for B‐chain‐containing PDGF molecules. Mol. Cell. Biol. 1988; 8: 3476–3486
  • Claesson‐Welsh L., Eriksson A., Westermark B., Heldin C. ‐H. cDNA cloning and expression of the human A‐type platelet‐derived growth factor (PDGF) receptor establishes structural similarity to the B‐type PDGF receptor. Proc. Natl. Acad. Sci. USA 1989; 86: 4917–4921
  • Feigner P. L., Gadek T. R., Holm M., Roman R., Chan H. W., Wenz M., Northrop J. P., Ringold G. M., Danielsen M. Lipofection: a highly efficient, lipid mediated DNA‐transfection procedure. Proc. Natl. Acad. Sci. USA 1987; 84: 7413–7417
  • Gospodarowicz D. Isolation and characterization of acidic and basic fibroblast growth factor. Methods Enzymol. 1987; 147: 106–119
  • Heldin C. ‐H., Westermark B. Platelet‐derived growth factor: Mechanism of action and possible in vivo function. Cell Regul. 1990; 1: 555–566
  • Heldin C. ‐H., Ernlund A., Rorsman C., Ronnstrand L. Dimerization of the B‐type platelet‐derived growth factor receptors occurs after ligand binding and is closely associated with receptor kinase activation. J. Biol. Chem. 1989; 264: 8905–8912
  • Hellerström C., Swenne I. Growth patterns of pancreatic islets in animals. The Diabetic Pancreas, B. W. Volk, E. R. Arquilla. Plenum, New York 1985; 53–79
  • Howell S. L., Taylor K. W. Potassium ions and the secretion of insulin by islets of Langerhans incubated in vitro. Biochem. J. 1968; 108: 17–24
  • Kanakaraj P., Raj S., Khan S. A., Bishayee S. Ligand‐induced interaction between α‐ and β‐type platelet‐derived growth factor (PDGF) receptors: Role of receptor heterodimers in kinase activation. Biochemistry 1991; 30: 1761–1767
  • Kissane J. M., Robins E. The fluorometric measurement of deoxyribonucleic acid in animal tissue with special reference to the central nervous system. J. Biol. Chem. 1958; 233: 184–188
  • Korsgren O., Sandler S., Schnell Landström A., Jansson L., Andersson A. Large‐scale production of fetal porcine pancreatic isletlike cell clusters. Transplantation (Baltimore) 1988; 45: 509–514
  • Lernmark A., Nathans A., Steiner D. F. Preparation and characterization of plasma membrane‐enriched fractions from rat pancreatic islets. J. Cell. Biol. 1976; 71: 606–623
  • Lev S., Givol D., Yarden Y. A specific combination of substrates is involved in signal transduction by the kit‐encoded receptor. EMBO J. 1991; 10: 647–654
  • Nielsen D. A., Welsh M., Casadaban M. J., Steiner D. F. Control of insulin gene expression in pancreatic β‐cells and in an insulin producing cell line, RIN‐5F cells. I. Effects of glucose and cyclic AMP on the transcription of insulin mRNA. J. Biol. Chem. 1985; 260: 13585–13589
  • Östman A., Bäckström G., Fong N., Betsholtz C., Wernstedt C., Hellman U., Westermark B., Valenzuela P., Heldin C. ‐H. Expression of three recombinant homodimeric isoforms of PDGF in Saccharomyces cerevisiae: Evidence for difference in receptor binding and functional activities. Growth Factors 1989; 1: 271–281
  • Partanen J., Makela T. P., Eerola E., Korhonen J., Hirvonen H., Claesson‐Welsh L., Alitalo K. FGFR‐4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. EMBO J. 1991; 10: 1347–1354
  • Rogelj S., Weinberg R. A., Fanning P., Klagsbrun M. Basic fibroblast growth factor fused to a signal peptide transforms cells. Nature 1988; 331: 173–175
  • Sambrook J., Fritsch E. F., Maniatis T. Extraction of RNA with guanidium thiocyanate followed by centrifugation in cesium chloride solutions. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y. 1989a; 7.19–7.22
  • Sambrook J., Fritsch E. F., Maniatis T. Selection of poly(A)+RNA. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y. 1989b; 7.26–7.29
  • Southern E. M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 1975; 98: 503–517
  • Swenne I., Bone A. J., Howell S. L., Hellerström C. Effects of glucose and amino acids on the biosynthesis of DNA and insulin in fetal rat islets maintained in tissue culture. Diabetes 1980; 29: 686–692
  • van Zoelen E. J. J. Receptor‐ligand interaction: a new method for determining binding parameters without a priori assumptions on non‐specific binding. Biochem. J. 1989; 262: 549–556
  • Welsh M., Welsh N., Nilsson T., Arkhammar P., Pepinsky R. B., Steiner D. F., Berggren P. O. Stimulation of pancreatic islet beta‐cell replication by oncogenes. Proc. Natl. Acad. Sci. USA 1988; 85: 116–120
  • Welsh M., Claesson‐Welsh L., Hallberg A., Welsh N., Betsholtz C., Arkhammar P., Nilsson T., Heldin C. ‐H., Berggren P. ‐O. Coexpression of the platelet‐derived growth factor (PDGF) B chain and the PDGF β receptor in isolated pancreatic islet cells stimulates DNA synthesis. Proc. Natl. Acad. Sci. USA 1990; 87: 5807–5811
  • Wennström S., Sandström C., Claesson‐Welsh L. cDNA cloning and expression of a human FGF receptor which binds acidic and basic FGF. Growth Factors 1991; 4: 197–208
  • Yarden Y., Ullrich A. Growth factor receptor tyrosine kinases. Annu. Rev. Biochem. 1988; 57: 443–478

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