Mutants of Basic Fibroblast Growth Factor Identify Different Cellular Response Programs

References

• Ausubel F. M., Brent R., Kingston R. E., Moore D. D., Seidman J. G., Smith J. A., Struhl K. Current Protocols in Molecular Biology. John Wiley & Sons Inc., NY 1994
   Google Scholar
• Basilico C., Moscatelli D. The FGF family of growth factors and oncogenes. Adv. Canc. Res. 1992; 59: 115–165
   PubMed Web of Science ®Google Scholar
• Bikfalvi A., Klein S., Pintucci G., Quarto N., Mignatti P., Rilkin D. B. Differential modulation of cell phenotype by different molecular weight forms of basic fibroblast growth factor: possible intracellular signaling by the high molecular weight forms. J. Cell Biol. 1995; 129: 233–243
   PubMed Web of Science ®Google Scholar
• Bugler B., Amalric F., Prats H. Alternative initiation of translation determines cytoplasmic or nuclear localization of basic tibroblast growth factor. Mol. Cell. Biol. 1991; 11: 573–577
   PubMed Web of Science ®Google Scholar
• Burgess W. H., Maciag T. The heparin-binding (fibroblast) growth factor family of proteins. Ann. Rev. Biochem. 1989; 58: 575–606
   PubMed Web of Science ®Google Scholar
• Canfield V., Emanuel J. R., Spickofski N., Levenson R., Margolskee R. F. Ouabain-resistent mutants of rat Na, K-ATPase α2 isoform identified by using an episomal expression vector. Mol. Cell. Biol. 1990; 10: 1367–1372
   PubMedGoogle Scholar
• Chamberlain C. G., McAvoy J. W. Induction of lens fibre differentiation by acidic and basic fibroblast growth factor (FGF). Growth Fuctors 1989; 1: 125–134
   PubMed Web of Science ®Google Scholar
• De Jong W. W., Lubsen N. H., Kraft H. J. Molecular evolution of the eye lens. Prog. Retina Eye Res. 1994; 13: 391–442
   Web of Science ®Google Scholar
• Gleizes P. E., Noaillac-Depeyre J., Gas N. Labeling of basic fibroblast growth factor with digoxigenin: a nonradioactive probe for biochemical and cytological applications. Anal. Biochem. 1994; 219: 360–367
   PubMed Web of Science ®Google Scholar
• Gleizes P. E., Noaillac-Depeyre J., Amalric F., Gas N. Basic fibroblast growth factor (FGF-2) internaliration through the heparan sulfate proteoglycans-mediated pathway: An ultrastructural approach. Eur. J. Cell Biol. 1995; 66: 47–59
   PubMed Web of Science ®Google Scholar
• Heath W. F., Cantrell A. S., Mayne N. G., Jaskunas S. R. Mutations in the heparin-binding domains of human basic tihroblast growth factor alter its biological activity. Biochemistry 1991; 30: 5608–5615
   PubMed Web of Science ®Google Scholar
• Hughes S. E., Hall P. A. The fibroblast growth factor and receptor multigene families. J. Puthol. 1993; 170: 219–221
   PubMed Web of Science ®Google Scholar
• Imamura T., Engleka K., Zhan X., Tokita Y., Forough R., Koeder D., Jackson A., Maier J. A., Hla T., Maciag T. Recovery of mitogenic activity of a growth factor mutant with a nuclear translocation sequence. Science 1990; 249: 1567–1570
   PubMed Web of Science ®Google Scholar
• Isacchi A., Statuto M., Chiesa R., Bergonzoni L., Rusnati M., Sarmientos P., Ragnotti G., Presta M. A six-amino acid deletion in basic fibroblast growth factor dissociates its mitogenic activity from its plasminogen activator-inducing capacity. Proc. Natl Acad. Sci. USA 1991; 88: 2628–2632
   PubMed Web of Science ®Google Scholar
• Jaye M., Schlessinger J., Dionne C. A. Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction. Biochim. Biophys. Acta 1992; 1135: 185–199
   PubMed Web of Science ®Google Scholar
• Johnson D. E., Williams L. T. Structural and functional diversity of the FGF receptor multigene family growth factors and oncogenes. Adv. Cancer Res 1993; 60: 1–41
   PubMed Web of Science ®Google Scholar
• Kiefer P., Acland P, Pappin D., Peters G., Dickson C. Competition between nuclear localization and secretory signals determines the subcellular fate of a single CUG-initiated form of FGF3. EMBO J. 1994; 13: 4126–4136
   PubMed Web of Science ®Google Scholar
• Li L. Y., Safran M., Aviezer D., Bohlen P., Seddon A. P., Yayon A. Diminished heparin binding of a basic fibroblast growth factor mutant is associated with reduced receptor binding, mitogenesis. plasminogen activator induction. and in vitro angiogenesis. Biochemistry 1994; 33: 10999–11007
   PubMed Web of Science ®Google Scholar
• Mason J. W. The ins and outs of fibroblast growth factors. Cell 1994; 78: 547–552
   PubMed Web of Science ®Google Scholar
• McAvoy J. W., Chamberlain C. G. Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration. Development 1989; 107: 221–228
   PubMed Web of Science ®Google Scholar
• McKeehan W. L., Kan M. Heparan sulfate fibroblast growth factor receptor complex: Structure-function relationships. Mol. Reprod. Dev. 1994; 39: 69–82
   PubMed Web of Science ®Google Scholar
• Mignatti P., Mazzieri R., Ritkin D. B. Expression of the urokinase receptor in vascular endothelial cells is stimulated by basic fibroblast growth factor. J. Cell Biol. 1991; 113: 1193–1201
   PubMedGoogle Scholar
• Murono E. P., Washbum A. L., Goforth D. P., Wu N. X. Evidence that both receptor-and heparan sulfate proteoglycan-bound basic fibroblast growth factor are internalized by cultured immature leydig cells. Mol, Cell. Endocrinol. 1993; 98: 81–90
   PubMedGoogle Scholar
• Patry V., Arnaud E., Amalric F., Prats H. Involvement of basic fibroblast growth factor NH2 terminus in nuclear accumulation. Growth Factors 1994a; 11: 163–174
   PubMed Web of Science ®Google Scholar
• Patry V., Bugler B., Amalric F., Prome J. C., Prats H. Purification and characterization of the 210-amino acid recombinant basic fibroblast growth factor form (FGF-2). FEBS Lett. 1994b; 349: 23–28
   PubMedGoogle Scholar
• Peek R., McAvoy J. W., Lubsen N. H., Schoenmak-Ers J. G. G. Rise and fall of crystallin gene messenger levels during fibroblast growth factor induced terminal differentiation of lens cells. Dev. Biol. 1992; 152: 152–160
   PubMed Web of Science ®Google Scholar
• Quarto N., Finger F. P., Rifkin D. B. The NH2-terminal extension of high molecular weight bFGF is a nuclear targeting signal. J. Cell. Phys. 1991; 147: 311–318
   PubMed Web of Science ®Google Scholar
• Saksela O., Moscatelli D., Ritkin D. B. The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen activator activity in capillary endothelial cells. J. Cell Biol. 1987; 105: 957–963
   PubMed Web of Science ®Google Scholar
• Shi E., Kan M., Xu J. M., Wang F., Hou J. Z., McKeehan W. L. Control of fibroblast growth factor receptor kinase signal transduction by heterodimeriza-tion of combinatorial splice variants. Mol. Cell. Bid. 1993; 13: 3907–3918
   Google Scholar
• Shimasaki S., Emoto N., Koba A., Mercado M., Shibata F., Cooksey K., Baird A., Ling N. Complementary DNA cloning and sequencing of rat ovarian basic fibroblast growth factor and tissue distribution study of its mRNA. Biochem. Biophys. Res. Comm. 1988; 157: 256–263
   PubMed Web of Science ®Google Scholar
• Vagner S., Gensac M. C., Maret A., Bayard F., Amalric F., Prats H., Prats A. C. Alternative translation of human fibroblast growth factor 2 mRNA occurs by internal entry of ribosomes. Mol. Cell. Biol. 1995; 15: 35–44
   PubMed Web of Science ®Google Scholar
• Van Hinsbergh V. W., Binnema D., Scheffer M. A., Sprengers E. D., Kooistra T., Rijken D. C. Production of plasminogen activators and inhibitor by serially propagated endothelial cells from adult human blood vessels. Arteriosclerosis 1987; 7: 389–400
   PubMedGoogle Scholar
• Wang J. K., Gao G. X., Goldfarb M. Fibroblast growth factor receptors have different signaling and mito genic potentials. Mol. Cell. Biol. 1994; 14: 181–188
   PubMed Web of Science ®Google Scholar
• Wiedlocha A, Falnes P., Madshus I H, Sandvig K, Olsnes S. Dual mode of signal transduction by externally added acidic fibroblast growth factor. Cell 1994; 76: 1039–1051
   PubMed Web of Science ®Google Scholar
• Wiedlocha A, Falnes P. O, Rapak A, Klingen-Berg Muñoz O, Olsnes S. Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization. Mol. Cell. Biol 1996; 16: 270–280
   PubMed Web of Science ®Google Scholar