Solid lipid nanoparticles for transdermal delivery of avanafil: optimization, formulation, in-vitro and ex-vivo studies

References

• Abdelbary G, Fahmy R. (2009). Diazepam-loaded solid lipid nanoparticles: design and characterization. AAPS PharmSciTech 10:211–19
   PubMed Web of Science ®Google Scholar
• Ahmed OAA, Afouna MI, El-Say KM, et al. (2014a). Optimization of self nanoemulsifying systems for the enhancement of in vivo hypoglycemic efficacy of glimepiride transdermal patches. Expert Opin Drug Deliv 11:1005–13
   PubMed Web of Science ®Google Scholar
• Ahmed OAA, Badr-Eldin SM, Tawfik MK, et al. (2014b). Design and optimization of self-nanoemulsifying delivery system to enhance quercetin hepatoprotective activity in paracetamol-induced hepatotoxicity. J Pharm Sci 103:602–12
   PubMed Web of Science ®Google Scholar
• Ahmed OAA, Hosny KM, Al-Sawahli MM, et al. (2015). Optimization of caseinate-coated simvastatin-zein nanoparticles: improved bioavailability and modified release characteristics. Drug Des Devel Ther 9:655–62
   PubMed Web of Science ®Google Scholar
• Ahmed TA, El-Say KM. (2014). Development of alginate-reinforced chitosan nanoparticles utilizing W/O nanoemulsification/internal crosslinking technique for transdermal delivery of rabeprazole. Life Sci 110:35–43
   PubMed Web of Science ®Google Scholar
• Allison M, Grant T, Obaidi M, et al. (2011). Pharmacokinetics of avanafil; a novel, rapidly-absorbed, selective PDE5 inhibitor for the treatment of mild to severe erectile dysfunction. J Sex Med 8:466–7
   Web of Science ®Google Scholar
• Almeida A, Runge S, Müller R. (1997). Peptide-loaded solid lipid nanoparticles (SLN): influence of production parameters. Int J Pharm 149:255–65
   Web of Science ®Google Scholar
• Al-Subaie MM, Hosny KM, El-Say KM, et al. (2015). Utilization of nanotechnology to enhance percutaneous absorption of acyclovir in the treatment of herpes simplex viral infections. Int J Nanomedicine 10:3973–85
   PubMed Web of Science ®Google Scholar
• Desai SJ, Singh P, Simonelli AP, Higuchi W. (1966). Investigation of factors influencing release of solid drug dispersed in inert matrices III. Quantitative studies involving the polyethylene plastic matrix. J Pharm Sci 55:1230–4
   PubMed Web of Science ®Google Scholar
• Doktorovova S, Souto EB, Silva AÑM. (2014). Nanotoxicology applied to solid lipid nanoparticles and nanostructured lipid carriers – a systematic review of in vitro data. Eur J Pharm Biopharm 87:1–18
   PubMed Web of Science ®Google Scholar
• El-Enany NM, Abdelal AA, Belal FF, et al. (2012). Development and validation of a repharsed phase-HPLC method for simultaneous determination of rosiglitazone and glimepiride in combined dosage forms and human plasma. Chem Cent J 6:1–10
   PubMed Web of Science ®Google Scholar
• El-Say KM, Ahmed TA, Badr-Eldin SM, et al. (2014). Enhanced permeation parameters of optimized nanostructured simvastatin transdermal films: ex vivo and in vivo evaluation. Pharm Dev Technol 14:1–8
   Google Scholar
• European Medicines Agency, Committee for Medicinal Products for Human Use (CHMP), CHMP assessment report, EMA, 321885, 2014. Available from: http://www ema europa eu/docs/en_GB/document_library/EPAR_-_Summary_for_the_public/human/002581/WC500145208 pdf [serial online] [last accessed 15 Nov 2014]
   Google Scholar
• Fahmy UA, Ahmed OA, Hosny KM. (2014). Development and evaluation of avanafil self-nanoemulsifying drug delivery system with rapid onset of action and enhanced bioavailability. AAPS Pharm Sci Tech 16:53–8
   PubMed Web of Science ®Google Scholar
• FDA. FDA approves Stendra for erectile dysfunction, 2015. Available from: http://www fda gov/newsevents/newsroom/pressannouncements/ucm302140 htm [serial online] [last accessed 5 Feb 2015]
   Google Scholar
• Hee-Jin H, Sunhui H, Sangok J, et al. (2014). Recombinant human epidermal growth factor (rhEGF)-loaded solid lipid nanoparticles: fabrication and their skin accumulation properties for topical rhEGF delivery. Bull Korean Chem Soc 35:2290–4
   Web of Science ®Google Scholar
• Higuchi T. (1962). Mechanism of sustained-action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J Pharm Sci 52:1145–9
   Web of Science ®Google Scholar
• Hu F, Hong Y, Yuan H. (2004). Preparation and characterization of solid lipid nanoparticles containing peptide. Int J Pharm 273:29–35
   PubMed Web of Science ®Google Scholar
• Ibrahim HM, Ahmed TA, Hussain MD, et al. (2014). Development of meloxicam in situ implant formulation by quality by design principle. Drug Dev Ind Pharm 40:66–73
   PubMed Web of Science ®Google Scholar
• Jenning V, Chafer-Korting M, Gohla S. (2000). Vitamin A-loaded solid lipid nanoparticles for topical use: drug release properties. J Control Release 66:115–26
   PubMed Web of Science ®Google Scholar
• Jung J, Choi S, Cho SH, et al. (2010). Tolerability and pharmacokinetics of avanafil, a phosphodiesterase type 5 inhibitor: a single- and multiple-dose, double-blind, randomized, placebo-controlled, dose-escalation study in healthy Korean male volunteers. Clin Ther 32:1178–87
   PubMed Web of Science ®Google Scholar
• Korsmeyer RW, Gurny R, Doelker E, et al. (1983). Mechanisms of potassium chloride release from compressed, hydrophilic, polymeric matrices: effect of entrapped air. J Pharm Sci 72:1189–91
   PubMed Web of Science ®Google Scholar
• Kumar S, Randhawa JK. (2013). High melting lipid based approach for drug delivery: solid lipid nanoparticles. Mater Sci Eng C 33:1842–52
   PubMed Web of Science ®Google Scholar
• Kuo Y, Chung C. (2011). Solid lipid nanoparticles comprising internal Compritol 888 ATO, tripalmitin and cacao butter for encapsulating and releasing stavudine, delavirdine and saquinavir. Colloids Surf B Biointerfaces 88:682–90
   PubMed Web of Science ®Google Scholar
• Kushwaha A, Vuddanda P, Karunanidhi P, et al. (2013). Development and evaluation of solid lipid nanoparticles of raloxifene hydrochloride for enhanced bioavailability. Biomed Res Int 2013:584549
   PubMed Web of Science ®Google Scholar
• Li L, Fang L, Xu X, et al. (2010). Formulation and biopharmaceutical evaluation of a transdermal patch containing letrozole. Biopharm Drug Dispos 31:138–49
   PubMed Web of Science ®Google Scholar
• Liu X, Sun Q, Wang H, et al. (2005). Microspheres of corn protein, zein, for an ivermectin drug delivery system. Biomaterials 26:109–15
   PubMed Web of Science ®Google Scholar
• Müller R, Runge S, Ravelli V, et al. (2006). Oral bioavailability of cyclosporine: solid lipid nanoparticles (SLN) versus drug nanocrystals. Int J Pharm 317:82–9
   PubMed Web of Science ®Google Scholar
• Reithmeier H, Herrmann J, Göpferich A. (2001). Development and characterization of lipid microparticles as a drug carrier for somatostatin. Int J Pharm 218:133–43
   PubMed Web of Science ®Google Scholar
• Ritger P, Peppas N. (1987). A simple equation for description of solute release. II. Fickian and anomalous release from swellable devices. J Control Release 5:37–42
   Google Scholar
• Rostami E, Kashanian S, Azandaryani AH, et al. (2014). Drug targeting using solid lipid nanoparticles. Chem Phys Lipids 181:56–61
   PubMed Web of Science ®Google Scholar
• Sanford M. (2013). Avanafil: a review of its use in patients with erectile dysfunction. Drugs Aging 30:853–62
   PubMed Web of Science ®Google Scholar
• Sarmento B, Martins S, Ferreira D, et al. (2007). Oral insulin delivery by means of solid lipid nanoparticles. Int J Nanomedicine 2:743–9
   PubMed Web of Science ®Google Scholar
• Shato H, Miyagawa Y, Okabe TMM, Sunada H. (1997). Dissolution mechanism of diclofenac sodium from wax matrix granules. J Pharm Sci 86:929–34
   PubMed Web of Science ®Google Scholar
• Urban-Morlan Z, Ganem-Rondero A, Melgoza-Contreras L, et al. (2010). Preparation and characterization of solid lipid nanoparticles containing cyclosporine by the emulsification-diffusion method. Int J Nanomedicine 5:611–20
   PubMed Web of Science ®Google Scholar
• Wagner J. (1969). Interpretation of percent dissolved-time plots derived from in vitro testing of conventional tablets and capsules. J Pharm Sci 58:1253–7
   PubMed Web of Science ®Google Scholar
• Wang R, Burnett A, Heller W, et al. (2012). Selectivity of avanafil, a PDE5 inhibitor for the treatment of erectile dysfunction: implications for clinical safety and improved tolerability. J Sex Med 2122–9
   PubMed Web of Science ®Google Scholar