136
Views
20
CrossRef citations to date
0
Altmetric
Research Article

Antioxidative properties of curcumin in the protection of blood platelets against oxidative stress in vitro

, , &
Pages 270-276 | Received 08 Dec 2010, Accepted 09 Dec 2010, Published online: 08 Feb 2011

References

  • Patrono C, Coller B, Fitz Gerald GA, Hirsh J, Roth G. Platelet-active drugs: The relationships among dose, effectiveness, and side effects: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 2004; 124: 234S–264S
  • Iuliano L, Colavita AR, Leo R, Practico D, Violi F. Oxygen free radicals and platelet activation. Free Radic Biol Med 1997; 22: 999–1006
  • Pignatelli P, Pulcinelli FM, Lenti L, Gazzaniga PP, Violi F. Hydrogen peroxide is involved in collagen-induced platelet activation. Blood 1998; 91: 484–490
  • Förstermann U. Nitric oxide and oxidative stress in vascular disease. Pflugers Arch - Eur J Physiol 2010; 459: 923–939
  • Ammon H, Wahl MA. Pharmacology of Curcuma longa. Planta Med 1991; 57: 1–7
  • Goel A, Kunnumakkara AB, Aggarwal BB. Curcumin as “curecumin”: From kitchen to clinic. Biochem Pharmacol 2008; 75: 787–809
  • Reddy PA, Lokesh BR. Studies on spice principles as antioxidant in the inhibition of lipid peroxidation of rat liver microsomes. Mol Cell Biochem 1992; 111: 117–124
  • Wang YJ, Pan MH, Cheng AL, Lin LI, Ho YS, Hsieh CY, Lin JK. Stability of curcumin in buffer solutions and characterization of its degradation products. J Pharm Biomed Anal 1997; 15: 1867–1876
  • Jovanovic SV, Steenken S, Boone CW, Siminic MG. H-Atom transfer is a preferred antioxidant mechanism of curcumin. J Am Chem Soc 1999; 121: 9677–9681
  • Ireson CR, Jones DJ, Orr S, Coughtrie MW, Boocock DJ, Williams ML, Farmer PB, Steward WP, Gescher AJ. Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine. Cancer Epidemiol Biomarkers Prev 2002; 11: 105–111
  • Aggarwal BB, Sundaram C, Malani N, Ichikawa H. Curcumin: The Indian solid gold. Adv Exp Med Biol 2007; 595: 1–75
  • Walkowiak B, Michalak E, Koziolkiewicz W, Cierniewski CS. Rapid photometric method for estimation of platelet count in blood plasma or platelet suspension. Thromb Res 1989; 56: 763–766
  • Pryor WA, Cueto R, Jin X, Koppenol WH, Ngu-Schwemlein M, Squadrito G, Uppu PL, Uppu RM. A practical method for preparing peroxynitrite solutions of low ionic strenght and free of hydrogen peroxide. Free Rad Biol Med 1991; 1: 75–83
  • Smith PK, Krohn RJ, Hermanson GT, Mallia AK, Gartner FH, Provezano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC. Measurment of protein using bicinchoninic acid. Anal Biochem 1985; 150: 76–85
  • Wachowicz B, Kustron J. Effect of cisplatin on lipid peroxidation in pig blood platelets. Cytobios 1992; 70: 41–47
  • Olas B, Nowak P, Kolodziejczyk J, Ponczek M, Wachowicz B. Protective effects of resveratrol against oxidative/nitrative modifications of plasma proteins and lipids exposed to peroxynitrite. J Nutr Biochem 2006; 17: 96–102
  • Buss H, Chan TP, Sluis KB, Domigan NM, Winterbourn CC. Protein carbonyl measurement by a sensitive ELISA method. Free Radic Biol Med 1997; 23: 361–366
  • Levine RL. Carbonyl modified proteins in cellular regulation, aging and disease. Free Radic Biol Med 2001; 32: 790–796
  • Sharma OP. Antioxidant activity of curcumin and related compounds. Biochem Pharmacol 1976; 25: 1811–1812
  • Mahakunakorn P, Tohda M, Murakami Y, Matsumoto K, Watanabe H, Vajragupta O. Cytoprotective and cytotoxic effects of curcumin: Dual action on H2O2 induced oxidative cell damage in NG108-15 cells. Biol Pharm Bull 2003; 26: 725–728
  • Manikandan P, Sumitra M, Aishwarya S, Manohar BM, Lokanadam B, Puvanakrishnan R. Curcumin modulates free radical quenching in myocardial ischaemia in rats. Int J Biochem Cell Biol 2004; 36: 1967–1980
  • Kelly MR, Xu J, Alexander KE, Loo G. Disparate effects of similar phenolic phytochemicals as inhibitors of oxidative damage to cellular DNA. Mutat Res 2001; 485: 309–318
  • Galati G, Sabzevari O, Wilson JX, O’Brien PJ. Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics. Toxicology 2002; 177: 91–104
  • Bartosz G. Peroxynitrite: Mediator of the toxic action of nitric oxide. Acta Biochim Pol 1996; 43: 645–659
  • Beckmann JS, Chen J, Ischiropoulos H, Crow JP. Oxidative chemistry of peroxynitrite. Methods Enzymol 1994; 233: 229–240
  • Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med 1998; 64: 353–356
  • Cheng AL, Hsu CH, Lin JK, Hsu MM, Ho YF, Shen TS, Ko JY, Lin JT, Lin BR, Ming-Shiang W, et al. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res 2001; 21: 2895–2900
  • Shishu, Gupta N, Aggarwal N. Bioavailability enhancement and targeting of stomach tumors using gastro-retentive floating drug delivery system of curcumin – “A technical note.”. AAPS Pharm SciTech 2008; 3: 810–813
  • Shaikh J, Ankola DD, Beniwal V, Singh D, Ravi Kumar MNV. Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer. Eur J Pharm Sci 2009; 37: 223–230
  • Shah BH, Nawaz Z, Pertani SA, Roomi A, Mahmood H, Saeed SA, Gilani AH. Inhibitory effect of curcumin, a food spice from turmeric, on platelet-activating factor- and arachidonic acid-mediated platelet aggregation through inhibition of thromboxane formation and Ca21 signaling. Biochem Pharmacol 1999; 58: 1167–1172
  • Esmon CT. Crosstalk between inflammation and thrombosis. Maturitas 2004; 47: 305–314
  • Berlett BS, Stadtman ER. Protein oxidation in aging, disease, and oxidative stress. J Biol Chem 1997; 272: 20313–20316
  • Davies MJ, Fu S, Wang H, Dean RT. Stable markers of oxidant damage to proteins and their application in the study of human disease. Free Radic Biol Med 1999; 27: 1151–1163
  • Shacker E. Protein oxidative damage. Methods Enzymol 2000; 319: 428–436
  • Nowak P, Zbikowska HM, Ponczek M, Kolodziejczyk J, Wachowicz B. Different vulnerability of fibrinogen subunits to oxidative/nitrative modifications induced by peroxynitrite: Functional consequences. Thromb Res 2007; 121: 163–174
  • Lufrano M, Balazy M. Interaction of peroxynitrite and other nitrating substances with human platelets: The role of glutathione and peroxynitrite permeability. Biochem Pharmacol 2003; 65: 515–523
  • Raghavendra RH, Naidu KA. Spice active principles as the inhibitors of human platelet aggregation and thromboxane biosynthesis. Prostaglandins Leukot Essent Fatty Acids 2009; 81: 73–78
  • Srivastava KC, Bordia A, Verma SK. Curcumin, a major component of food spice turmeric (Curcuma longa) inhibits aggregation and alters eicosanoid metabolism in human blood platelets. Prostaglandins Leukot Essent Fatty Acids 1995; 52: 223–227
  • Joe B, Lokesh BR. Role of capsaicin, curcumin and dietary 3 fatty acids in lowering the generation of reactive oxygen species in rat peritoneal macrophages. Biochim Biophys Acta 1994; 1224: 255–263
  • Halliwell B, Chirico S. Lipid peroxidation: Its mechanism, measurement, and significance. Am J Clin Nutr 1993; 57: 715–725
  • Sreejayan Rao MN. Curcuminoids as potent inhibitors of lipid peroxidation. J Pharm Pharmacol 1994; 46: 1013–1016
  • Wright JS. Predicting the antioxidant activity of curcumin and curcuminoids. J Mol Structure 2002; 591: 207–217
  • Ak T, Gulcin I. Antioxidant and radical scavenging properties of curcumin. Chemico-Biological Interact 2008; 174: 27–37
  • Barclay LRC, Vinqvist MR, Mukai K, Goto H, Hashimoto Y, Tokunaga A, Uno H. On the antioxidant mechanism of curcumin: Classical methods are needed to determine antioxidant mechanism and activity. Org Lett 2000; 2: 2841

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.