Comparison of common platelet receptors between the chacma baboon (Papio ursinus) and human for use in pre-clinical human-targeted anti-platelet studies

References

• American Heart Association and American Stroke Association. Heart disease and stroke statistics, 2006 – Update. http://www.americanheart.org/downloadable/heart/1140534985281Statsupdate06book.pdf [last accessed 27 March 2009].
   Google Scholar
• Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Blaha MJ, Dai S, Ford ES, Fox CS, Franco S, et al. Heart disease and stroke statistics – 2014 Update: A report from the American Heart Association. Circulation 2014;129:e28–e292.
   Google Scholar
• World Health Organization (2013). WHO Fact sheet No. 310. The Top 10 Causes of Death. http://www.who.int/mediacentre/factsheets/fs310/en/# [last accessed 24 March 2014].
   Google Scholar
• World Health Organization (2011). WHO Fact sheet No. 317. Cardiovascular diseases. www.who.int/mediacentre/factsheets/fs317/en/print.html [last accessed 13 November 2014].
   Google Scholar
• Cannon CP, Brindis RG, Chaitman BR, Cohen DJ, Cross CJT Jnr, Drozda JP Jnr, Fesmire FM, Fintel DJ, Fonarow GC, Fox KA, et al. 2013 ACCF/AHA KJey data elements and definitions for measuring the clinical management and outcomes of patients with acute coronary syndromes and coronary artery disease: A report of the American College of Cardiology Foundation/ American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Acute Coronary Syndromes and Coronary Artery Disease Clinical Data Standards). Circulation 2013; 127:1052–1089.
   Web of Science ®Google Scholar
• Cauwenberghs N, Meiring M, Vauterin S, Van Wyk V, Lamprecht S, Roodt JP, Novák L, Harsfalvi J, Deckmyn H, Kotzé HF. Antithrombotic effect of platelet glycoprotein ib-blocking monoclonal antibody fab fragments in nonhuman primates. Arterioscler Thromb Vasc Biol 2000; 20:1347–1353.
   PubMed Web of Science ®Google Scholar
• Fontayne A, Meiring M, Lamprecht S, Roodt J, Demarsin E, Barbeaux P, Deckmyn H. The humanized anti-glycoprotein Ib monoclonal antibody h6B4-Fab is a potent and safe antithrombotic in a high shear rate arterial thrombosis model in baboons. Thromb Haemost 2008; 100:670–677.
   PubMed Web of Science ®Google Scholar
• Ulrichts H, Silence K, Schoolmeester A, De Jaegere P, Rossenu S, Roodt J, Priem S, Lauwereys M, Casteels P, Van Bockstaele F, et al. Antithrombotic drug candidate ALX-0081 shows superior preclinical efficacy and safety compared with current marketed antiplatelet drugs. Blood 2011;118:757–765.
   PubMed Web of Science ®Google Scholar
• Cook DJ, Teves L, Tymianski M. Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain. Nature 2012;483:213–217.
   PubMed Web of Science ®Google Scholar
• Mason RG, Wolf RH, Zucker WH, Shinoda BA, Mohammad SF. Effects of antithrombotic agents evaluated in a nonhuman primate vascular shunt model. Am J Pathol 1976; 83:557–568.
   PubMed Web of Science ®Google Scholar
• Janse van Rensburg WJ, Roodt JP, Lamprecht S, Meiring SM, Badenhorst PN. Tirofiban versus abciximab: Tirofiban is administered at suboptimal dosages when evaluated in an arterial thrombosis model in non-human primates. Clin Exp Med 2012;12:257–263.
   PubMed Web of Science ®Google Scholar
• Feys HB, Roodt J, Vandeputte N, Pareyn I, Lamprecht S, van Rensburg JW, Anderson PJ, Budde U, Louw VJ, Badenhorst PN, et al. Thrombotic thrombocytopenic purpura directly linked with ADAMTS13 inhibition in the baboon (Papio ursinus). Blood 2010;116(12):2005–2010.
   PubMed Web of Science ®Google Scholar
• Callewaert F, Roodt JP, Ulrichts H, Stohr T, Janse van Rensburg W, Lamprecht S, Rossenu S, Priem S, Willems W, Holz JB. Evaluation of efficacy and safety of the anti-VWF Nanobody ALX-0681 in a preclinical baboon model of acquired thrombotic thrombocytopenic purpura. Blood 2012; 120(17):3603–3610.
   PubMed Web of Science ®Google Scholar
• Feys H, Roodt J, Vandeputte N, Pareyn I, Mottl H, Hou S, Lamprecht S, J Van Rensburg W, Deckmyn H, and Vanhoorelbeke K. Inhibition of von Willebrand factor-platelet glycoprotein Ib interaction prevents and reverses symptoms of acute acquired thrombotic thrombocytopenic purpura in baboons. Blood 2012; 120(17):3611–3614.
   Google Scholar
• Janse van Rensburg WJ, Badenhorst PN, Roodt JP. The Cape Chacma baboon is not suitable for evaluating human targeted anti-GPVI agents. Platelets 2015; 26(6):552–557.
   Google Scholar
• Cattaneo M, Lecchi A, Zighetti ML, Lussana F. Platelet aggregation studies: Autologous platelet-poor plasma inhibits platelet aggregation when added to platelet-rich plasma to normalize platelet count. Haematologica 2007;92:694–697.
   PubMed Web of Science ®Google Scholar
• Labea PJ and Pretorius PJ. Newborn screening for classic galactosaemia and primary congenital hypothyroidism in the Nkangala district of Mpumalanga Province, South Africa. S Afr J Child Health 2008;2:19–22.
   Google Scholar
• Primer3Plus. http://www.bioinformatics.nl/cgi-bin/primer3plus/primer3plus.cgi/ [last accessed 13 November 2014].
   Google Scholar
• Chromas Lite. http://chromas-lite.software.informer.com/2.0 [ last accessed 26 March 2014].
   Google Scholar
• Lalign Sequence Alignment Program. www.ch.embnet.org/software/LALIGN_form.html [last accessed 13 November 2014].
   Google Scholar
• Huang X and Miller W. A time-efficient, linear-space local similarity algorithm. Adv Appl Math 1991; 12:337–357.
   Web of Science ®Google Scholar
• ExPASy translate tool. http://web.expasy.org/translate [last accessed 13 November 2014].
   Google Scholar
• Meyer M & Schellenberg I. Platelet membrane glycoprotein Ib: Genetic polymorphism detected in the intact molecule and proteolytic fragments. Thromb Res 1990;58:233–242.
   PubMed Web of Science ®Google Scholar
• Shi M, Qiao J, Shen Y, Lu Y, Chen Y, Cheng J. Cloning of porcine platelet glycoprotein Ibα and comparison with the human homolog. Comparative Med 2012;62:291–297.
   PubMed Web of Science ®Google Scholar
• Lόpez JA, Ludwig EH, McCarthy BJ. Polymorphism of human glycoprotein Ibα Results from a variable number of tandem repeats of a 13-amino acid sequence in the mucin-like macroglycopeptide region. J Biol Chem 1992;267:10055–10061.
   PubMed Web of Science ®Google Scholar
• Cross MJ. Effect of fibrinogen on the aggregation of platelets by adenosine diphosphate. Thromb Diathesis Haemorrhagica 1964;12:524–527.
   PubMedGoogle Scholar
• Botma J, Mogongoa LF, Jaftha AD, Janse van Rensburg W. Reference ranges for platelet indices using the Sysmex XE-2100 blood analyser. Med Technol SA 2012;26:17–21.
   Google Scholar
• Mustard JF, Packham MA, Kinlough-Rathbone RL, Perry DW, Regoeczi E. Fibrinogen and ADP-induced platelet aggregation. Blood 1978;52:453–466.
   PubMed Web of Science ®Google Scholar
• Bennett JS, Vilaire G. Exposure of platelet fibrinogen receptors by adp and epinephrine. J Clin Investigation 1979;64:1393–1401.
   PubMed Web of Science ®Google Scholar
• Marguerie GA, Plow EF, Edgington TS. Human platelets possess and inducible and saturable receptor specific for fibrinogen. J Biol Chem 1979;254:5357–5363.
   PubMed Web of Science ®Google Scholar
• Niewiarowski S, Budzynski AZ, Lipinski B. Significance of the intact polypeptide chains of human fibrinogen in ADP-induced platelet aggregation. Blood 1977;49:635–644.
   PubMed Web of Science ®Google Scholar
• Nachman RL, Leung LL. Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen. J Clin Investigation 1982;69:263–269.
   PubMed Web of Science ®Google Scholar
• Gogstad GO, Brosstad F, Krutnes MB, Hagen I, Solum NO. Fibrinogen-binding properties of the human platelet glycoprotein IIb-IIIa complex: A study using crossed-radioimmunoelectrophoresis. Blood 1982;60:663–671.
   PubMed Web of Science ®Google Scholar
• Marguerie GA, Thomas-Maison N, Ginsberg MH, Plow EF. The platelet-fibrinogen interaction: Evidence for proximity of the Aα chain of fibrinogen to platelet membrane glycoproteins IIb/III. Eur J Biochem 1984;139:5–11.
   PubMedGoogle Scholar
• Landolfi R, De Cristofaro R, De Candia E, Rocca B, Bizzi B. Effect of fibrinogen concentration on the velocity of platelet aggregation. Blood 1991;78:377–381.
   PubMed Web of Science ®Google Scholar
• Hainsey BM, Hubbard GB, Leland MM, Brasky KM. Clinical parameters of the normal baboons (Papio species) and chimpanzees (Pan troglodytes). Lab An Sc 1993;43:236–243.
   PubMedGoogle Scholar
• Cattaneo M. The platelet P2Y12 receptor for adenosine diphosphate: Congenital and drug-induced defects. Blood 2011;117:2102–2112.
   PubMed Web of Science ®Google Scholar
• Algaier I, Jakubowski JA, Asai F, Von Kϋgelgen I. Interaction of the active metabolite of prasugrel, R-138727, with cysteine 97 and cysteine 175 of the human P2Y12 receptor. J Thromb Haemost 2008;6:1908–1914.
   PubMed Web of Science ®Google Scholar
• Ding Z, Bynagari YS, MADA SR, Jakubowski JA, Kunapuli SP. Studies on the role of the extracellular cysteines and oligometric structures of the P2Y12 receptor when interacting with antagonists. J Thromb Haemost 2009;7:232–234.
   PubMed Web of Science ®Google Scholar
• Zhang K, Zhang J, Gao ZG, Zhang D, Zhu L, Han GW, Moss SM, Paoletta S, Kiselev E, Lu W, et al. Structure of the human P2Y12 receptor in complex with an antithrombotic drug. Nature 2014;509:115–118.
   PubMed Web of Science ®Google Scholar
• Zhang J, Zhang K, Goa ZG, Paoletta S, Zhang D, Han GW, Li T, Ma L, Zhang W, Mϋller CE, et al. Agonist-bound structure of the human P2Y12 receptor. Nature 2014;509:119–122.
   PubMed Web of Science ®Google Scholar
• Ignatovica V, Megnis K, Lapins M, Schiöth HB, Klovins J. Identification and analysis of functionally important amino acids in human purinergic 12 receptor using a Saccharomyces cerevisiae expression system. FEBS J 2012;279:180–191.
   PubMed Web of Science ®Google Scholar
• Lin ECK, Ratnikov BI, Tsai PM, Carron CP, Myers DM, Barbas III CF, Smith JW. Identification of a region in the integrin β3 subunit that confers ligand binding specificity. J Biol Chem 1997;272:23912–23920.
   PubMed Web of Science ®Google Scholar
• Kamata T, Tieu KK, Irie A, Springer TA, Tkada Y. Amino acid residues in the αIIb subunit that are crit ical for ligand binding to integrin αIIbβ3 are clustered in the β-propeller model. J Biol Chem 2001;276:44275–44283.
   PubMed Web of Science ®Google Scholar
• Vanhoorelbeke K, Ulrichts H, Van de Walle G, Fontayne A, Deckmyn H. Inhibition of platelet glycoprotein Ib and its antithrombotic potential. Curr Pharm Design 2007;13:2684–2697.
   PubMed Web of Science ®Google Scholar
• Katagiri Y, Hayashi Y, Yamamoto K, Tanoue K, Kosaki G, Yamazaki H. Localization of von Willebrand factor and thrombin-interactive domains on human platelet glycoprotein Ib. Thromb Haemost 1990;63:122–126.
   PubMed Web of Science ®Google Scholar
• Fontayne A, De Maeyer B, De Maeyer M, Yamashita M, Matsushita T, Deckmyn H. Paratope and epitope mapping of the antithrombotic antibody 6B4 in complex with platelet glycoprotein Ibα. J Biol Chem 2007;282:23517–23524.
   PubMed Web of Science ®Google Scholar
• Andrews RK, Gardiner EE, Shen Y, Whisstock JC, Berndt MC. Glycoprotein Ib-IX-V. Int J Biochem Cell Biol 2003;35:1170–1174.
   PubMed Web of Science ®Google Scholar
• Gu M, Xi X, Englund GD, Berndt MC, Du X. Analysis of the roles of 14-3-3 in the platelet glycoprotein Ib-IX-mediated activation of integrin αIIbβ3 using a reconstituted mammalian cell expression model. J Cell Biol 1999;147:1085–1096.
   PubMed Web of Science ®Google Scholar
• Du X, Fox JE, Pei S. Identification of a binding sequence for the 14-3-3 protein within the cytoplasmic domain of the adhesion receptor, platelet glycoprotein Ibα. J Biol Chem 1996; 271:7362–7367.
   PubMed Web of Science ®Google Scholar
• Laffan M, Manning R. 2006. Investigation of haemostasis. In: Lewis SM, Bain BJ, Bates I, editors. Dacie and Lewis practical haematology. 10th Edition. Philadelphia: Churchill Livingstone Elsevier. pp 379–441.
   Google Scholar