Vitamin C and pressure sores

References

• King C G. Present knowledge of ascorbic acid (vitamin C). Nutr Rev 1968; 26: 33–43
   PubMedGoogle Scholar
• Murad S, Grove D, Lindberg K A., et al. Regulation of collagen synthesis by ascorbic acid. Proc Natl Acad Sci USA 1981; 78: 2879–82
   PubMed Web of Science ®Google Scholar
• Kivirikko K I., Prockop D J. Enzymatic hydroxylation of proline and lysine in protocollagen. Proc Natl Acad Sci USA 1967; 57: 782–9
   PubMed Web of Science ®Google Scholar
• Geesin J C., Darr D, Kaufman R, et al. Ascorbic acid specifically increases type I and III procollagen messenger RNA levels in human skin fibroblasts. J Invest Dermatol 1988; 90: 420–4
   PubMed Web of Science ®Google Scholar
• Houglum K P., Brenner D A., Chojkier M. Ascorbic acid stimulation of collagen biosynthesis independent of hydroxylation. Am J Clin Nutr 1991; 54: 1141S–3S
   Google Scholar
• Orgill D, Demling R H. Current concepts and approaches to wound healing. Crit Care Med 1988; 16: 899–908
   PubMed Web of Science ®Google Scholar
• Schwartz P L. Ascorbic acid in wound healing - a review. J Am Diet Assoc 1970; 56: 497–503
   PubMedGoogle Scholar
• Hunter T, Rajan K T. The role of ascorbic acid in the pathogenesis and treatment of pressure sores. Paraplegia 1971; 8: 211–16
   PubMedGoogle Scholar
• Collins C K., Lewis E A., Ringsdorf W M., Jr, et al. Effect of ascorbic acid on oral healing in guinea pigs. Int J Vit Nutr Res 1967; 37: 492–5
   Google Scholar
• Bartlett M, Jones C M., Ryan A E. Vitamin C and wound healing III: Ascorbic acid content and tensile strength of healing wounds in human beings. N Engl J Med 1942; 226: 474–81
   Google Scholar
• Hartzell J B., Stone W B. The relationship of the concentration of ascorbic acid of the blood to the tensile strength of wounds. Surg Gynaecol Obstet 1942; 75: 1–8
   Google Scholar
• Grindlay J H., Waugh J M. Plastic sponge which acts like a framework for living tissue. Arch Surg 1951; 63: 288–301
   Web of Science ®Google Scholar
• Bartlett M, Jones C M., Ryan A E. Vitamin C and wound healing II: Experimental wounds in guinea pigs. N Engl J Med 1942; 226: 469–73
   Google Scholar
• Taffel M, Harvey S C. Effect of absolute and partial vitamin C deficiency on healing of wounds. Proc Soc Exp Biol 1938; 38: 518–20
   Google Scholar
• Abt A F., Von Schuching S, Roe J H. Connective tissue studies. 1. Relation of dietary and tissue levels of ascorbic acid to the healing of surgically-induced wounds in guinea pigs. Bull John Hopkins Hosp 1959; 104: 163–6
   PubMedGoogle Scholar
• Abt A F., Von Schuching S, Roe J H. Connective tissue studies. 3. Ascorbic acid, collagen, hexosamine distribution and histology of connective tissue in scars produced in guinea pigs on various vitamin C dietary levels following wounding by abdominal incision. J Nutr 1960; 70: 427–31
   PubMed Web of Science ®Google Scholar
• Abt A F., Von Schuching S. Catabolism of L-ascorbic-1-C14-acid as a measure of its utilisation in the intact and wounded guinea pig on scorbutic, maintenance and saturation diets. Ann NY Acad Sci 1961; 92: 148–58
   PubMedGoogle Scholar
• Levenson S M., Crowley L V., Geever E F., et al. Some studies of wound healing: experimental methods, effect of ascorbic acid and effect of deuterium oxide. J Trauma 1964; 4: 543–50
   PubMedGoogle Scholar
• Kramer M, Fillios L C., Bowler E C. Ascorbic acid treatment on early collagen production and wound healing in the guinea pig. J Periodontol 1979; 10: 189–92
   Google Scholar
• Klemm W R. Enhanced healing of skin wounds in dogs with systemic and locally administered drugs. Experientia 1967; 23: 55–7
   PubMedGoogle Scholar
• Pfister R R., Paterson C A., Hayes S A. Topical ascorbate decreases the incidence of corneal ulceration after experimental alkali burns. Invest Ophthalmol Vis Sci 1978; 17: 1019–24
   PubMedGoogle Scholar
• Goldsmith G A. Human requirements for vitamin C and its use in clinical medicine. Ann NY Acad Sci 1961; 92: 230–8
   PubMedGoogle Scholar
• Crandon J H., Lennihan R, Jr, Mikai S, et al. Ascorbic acid economy in surgical patients. Ann NY Acad Sci 1961; 92: 246–50
   PubMedGoogle Scholar
• Crandon J H., Lund C C., Dill D B. Experimental human scurvy. N Engl J Med 1940; 223: 353–7
   Google Scholar
• Hunt A H. The role of vitamin C in wound healing. Br J Surg 1941; 28: 436–41
   Google Scholar
• Cheraskin E. The ecology of periodontal disease. Report on proceedings. Workshop on diet, nutrition and periodontal disease. Am Soc Prevent Dentistry 1974; 47: 7–27
   Google Scholar
• Hodges R F., Baker E M., Hood J, et al. Experimental scurvy in man. Am J Clin Nutr 1969; 22: 535–48
   PubMed Web of Science ®Google Scholar
• Bourne G H. The effect of vitamin C on the healing of wounds. Proc Nutr Soc 1946; 4: 204–16
   PubMedGoogle Scholar
• Wolfer J A., Farmer C J., Carroll W W., et al. An experimental study in wound healing in vitamin C depleted human subjects. Surg Gynaecol Obstet 1947; 84: 1–15
   Google Scholar
• Schorah C J., Habibzadeh N, Hancock M, et al. Changes in plasma and buffy layer vitamin C concentrations following major surgery: what do they reflect?. Ann Clin Biochem 1986; 23: 566–70
   PubMedGoogle Scholar
• Burr R G., Rajan K T. Leucocyte ascorbic acid and pressure sores in paraplegia. Br J Nutr 1972; 28: 275–81
   PubMedGoogle Scholar
• Williams C M., Lines C M., McKay E C. Iron and zinc status in multiple sclerosis patients with pressure sores. Eur J Clin Nutr 1988; 42: 321–8
   PubMed Web of Science ®Google Scholar
• Afifi A M., Ellis L, Huntsman R G., et al. High dose ascorbic acid in the management of thalassaemia leg ulcers - a pilot study. Br J Dermatol 1975; 92: 339–41
   PubMed Web of Science ®Google Scholar
• Versluysen M. How elderly patients with femoral fracture develop pressure sores. B M J 1986; 292: 1311–13
   PubMedGoogle Scholar
• Goode H F., Burns E, Walker B E. Vitamin C depletion and pressure sores in elderly patients with femoral neck fracture. B M J 1992; 305: 925–7
   PubMedGoogle Scholar
• Bergstrom N, Braden B. A prospective study of pressure sore risk among institutionalised elderly. J Am Geriatr Soc 1992; 40: 747–58
   PubMed Web of Science ®Google Scholar
• Brown K M., Seabrook N A. Nutritional influences on recovery and length of stay in elderly women following femoral fracture. Proc Nutr Soc 1992; 51: 132A, abstract
   Google Scholar
• Brocklehurst J C., Griffiths L L., Taylor G F., et al. The clinical features of chronic vitamin deficiency: a therapeutic trial in geriatric hospital patients. Gerontol Clin 1968; 10: 309–20
   PubMedGoogle Scholar
• Taylor T V., Rimmer S, Day B, et al. Ascorbic acid in the treatment of pressure sores. Lancet 1974; ii: 544–6
   Google Scholar