359
Views
22
CrossRef citations to date
0
Altmetric
Papers Presented at the 2nd Workshop on Radiation and Multidrug Resistance Mediated via the Tumour-Microenvironment

DNA double-strand break signalling: X-ray energy dependence of residual co-localised foci of γ-H2AX and 53BP1

, , &
Pages 1042-1050 | Received 09 Apr 2009, Accepted 16 Jul 2009, Published online: 06 Nov 2009

References

  • Anderson L, Henderson C, Adachi Y. 2001. Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage. Molecular and Cellular Biology 21(5):1719–1729.
  • Beyreuther E, Dörr W, Lehnert A, Lessmann E, Pawelke J. 2009. RBE of 25 kV and 10 kV X-rays for the induction of chromosomal aberrations in two human mammary epithelial cell lines. Radiation and Environmental Biophysics 48(3):333–340.
  • Blöcher D. 1988. DNA double-strand break determines the RBE of a-particles. International Journal of Radiation Biology 54(5):761–771.
  • Eke I, Sandfort V, Storch K, Baumann M, Röper B, Cordes N. 2007. Pharmacological inhibition of EGFR tyrosine kinase affects ILK-mediated cellular radiosensitization in vitro. International Journal of Radiation Biology 83(11–12):793–802.
  • GEANT4 collaboration. 2003. GEANT 4 – a simulation toolkit. Nuclear Instruments and Methods in Physics Research A 506(3):250–303.
  • Hill MA. 2004. The variation in biological effectiveness of X-rays and gamma rays with energy. Radiation Protection Dosimetry 112(4):471–481.
  • Hubbell, JH, Seltzer, SM. 2004. Tables of X-ray mass attenuation coefficients and mass energy-absorption coefficients (version 1.4). National Institute of Standards and Technology, Gaithersburg, MD. [Available online: http://physics.nist.gov/xaamdi].
  • Ichijima Y, Sakasai R, Okita N, Asahina K, Mizutani S, Teraoka H. 2005. Phosphorylation of histone H2AX at M phase in human cells without DNA damage response. Biochemical and Biophysical Research Communications 336(3):807–812.
  • Kegel P, Riballo E, Kühne M, Jeggo PA, Löbrich M. 2007. X-irradiation of cells on glass slides has a dose doubling impact. DNA Repair (Amst) 6(11):1692–1697.
  • Kinner A, Wu W, Staudt C, Iliakis G. 2008. γ-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin. Nucleic Acids Research 36(17):5678–5694.
  • Krumrey M, Ulm G, Schmid E. 2004. Dicentric chromosomes in monolayers of human lymphocytes produced by monochromatized synchrotron radiation with photon energies from 1.83 keV to 17.4 keV. Radiation and Environmental Biophysics 43(1):1–6.
  • Leatherbarrow EL, Harper JV, Cucinotta FA, O'Neill P. 2006. Induction and quantification of γ-H2AX foci following low and high LET-irradiation. International Journal of Radiation Biology 82(2):111–118.
  • Lehnert A, Dörr W, Lessmann E, Pawelke J. 2008. RBE of 10 kV X Rays determined for the human mammary epithelial cell line MCF-12A. Radiation Research 169(3):330–336.
  • Lehnert A, Lessmann E, Pawelke J, Dörr W. 2006. RBE of 25 kV X-rays for the survival and induction of micronuclei in the human mammary epithelial cell line MCF-12A. Radiation and Environmental Biophysics 45(4):253–260.
  • Löbrich M, Jeggo PA. 2007. The impact of a negligent G2/M checkpoint on genomic instability and cancer induction. Nature reviews. Cancer 7(11):861–869.
  • MacPhail SH, Banáth JP, Yu TY, Chu EH, Lambur H, Olive PL. 2003a. Expression of phosphorylated histone H2AX in cultured cell lines following exposure to X-rays. International Journal of Radiation Biology 79(5):351–358.
  • MacPhail SH, Banáth JP, Yu Y, Chu E, Olive PL. 2003b. Cell cycle-dependent expression of phosphorylated histone H2AX: Reduced expression in unirradiated but not X-irradiated G1-phase cells. Radiation Research 159(6):759–767.
  • Marková E, Schultz N, Belyaev IY. 2007. Kinetics and dose-response of residual 53BP1/gamma-H2AX foci: co-localization, relationship with DSB repair and clonogenic survival. International Journal of Radiation Biology 83(5):319–329.
  • Ponomarev AL, Costes SV, Cucinotta FA. 2008. Stochastic properties of radiation induced DSB: DSB distributions in large scale chromatin loops, the HPRT gene and within visible volumes of DNA repair foci. International Journal of Radiation Biology 84(11):916–929.
  • Rappold I, Iwabuchi K, Date T, Chen J. 2001. Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways. The Journal of Cell Biology 153(3):613–620, Erratum in: The Journal of Cell Biology 2001; 154(2):469.
  • Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. 1998. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. Journal of Biological Chemistry 273(10):5858–5868.
  • Roos H, Schmid E. 1998. Analysis of chromosomal aberrations in human peripheral lymphocytes induced by 5.4 keV X rays. Radiation and Environmental Biophysics 36(4):251–254.
  • Rothkamm K, Löbrich M. 2003. Evidence for a lack of DNA double-strand break repair in human cells exposed to very low X-ray doses. Proceedings of the National Academy of Science of the USA 100(9):5057–5062.
  • Sasaki MS, Kobayashi K, Hieda K, Yamada T, Ejima Y, Maezawa H, Furusawa Y, Ito T, Okada S. 1989. Induction of chromosome aberrations in human lymphocytes by monochromatic X-rays of quantum energy between 4.8 and 14.6 keV. International Journal of Radiation Biology 56(6):975–988.
  • Schmid E, Regulla D, Kramer HM, Harder D. 2002. The effect of 29 kV X rays on the dose response of chromosome aberrations in human lymphocytes. Radiation Research 158(6):771–777.
  • SSK – German Commission on Radiological Protection. 2005. Evaluation of the relative biological effectiveness of different types of ionizing radiation. Statement of the German Commission on Radiological Protection. Band 53, Bonn: Urban & Fischer.
  • SSK – German Commission on Radiological Protection. 2008. Evaluation of the effectiveness of quality-assured mammography screening in Germany. Statement of the German Commission on Radiological Protection. www.ssk.de [in German].
  • Stampfer MR, Bartley JC. 1985. Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene. Proceedings of the National Academy of Science of the USA 82(8):2394–2398.
  • Stampfer MR, Yaswen P. 2000. Culture models of human mammary epithelial cell transformation. Journal of Mammary Gland Biology and Neoplasia 5(4):365–378.
  • Torudd J, Protopopova M, Sarimov R, Nygren J, Eriksson S, Marková E, Chovanec M, Selivanova G, Belyaev IY. 2005. Dose-response for radiation-induced apoptosis, residual 53BP1 foci and DNA-loop relaxation in human lymphocytes. International Journal of Radiation Biology 81(2):125–138.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.