10 Gy total body irradiation increases risk of coronary sclerosis, degeneration of heart structure and function in a rat model

References

• Ahlers I, Misurova E, Praslicka M, Tigranyan RA. 1976. Biochemical changes in rats flown on board the Cosmos 690 biosatellite. Life Science Space Research 14:185–188.
   PubMedGoogle Scholar
• Baker J, Su J, Hsu A, Shi Y, Zhao M, Xu H, Eis A, Komorowski R, Wang J, Fu X, Konorev E, Jensen E, Tweddell J, Gross G. 2008. Human thrombopoietin reduces myocardial infarct size, apoptosis and stunning following ischemia/reperfusion in rats. Cardiovascular Research 77:44–53.
   PubMed Web of Science ®Google Scholar
• Boerma M, Kruse JJ, van Loenen M, Klein HR, Bart CI, Zurcher C, Wondergem J. 2004. Increased deposition of von Willebrand factor in the rat heart after local ionizing irradiation. Strahlentherapie und Onkologie 180:109–116.
   PubMed Web of Science ®Google Scholar
• Carr ZA, Land CE, Kleinerman RA, Weinstock RW, Stovall M, Griem ML, Mabuchi K. 2005. Coronary heart disease after radiotherapy for peptic ulcer disease. International Journal of Radiation Oncology Biology Physics 61:842–850.
   PubMed Web of Science ®Google Scholar
• Cilliers GD, Harper IS, Lochner A. 1989. Radiation-induced changes in the ultrastructure and mechanical function of the rat heart. Radiotherapy and Oncology 16:311–326.
   PubMed Web of Science ®Google Scholar
• Cohen EP, Fish BL, Sharma M, Li XA, Moulder JE. 2007. Role of the angiotensin II type-2 receptor in radiation nephropathy. Translational Research 150:106–115.
   PubMedGoogle Scholar
• Cohen EP, Robbins ME. 2003. Radiation nephropathy. Seminars in Nephrology 23:486–499.
   PubMed Web of Science ®Google Scholar
• Coleman CN, Blakely WF, Fike JR, MacVittie TJ, Metting NF, Mitchell JB, Moulder JE, Preston RJ, Seed TM, Stone HB, Tofilon PJ, Wong RS. 2003. Molecular and cellular biology of moderate-dose (1–10 Gy) radiation and potential mechanisms of radiation protection: report of a workshop at Bethesda, Maryland; December 17–18, 2001. Radiation Research 159:812–834.
   PubMedGoogle Scholar
• Datta PK, Moulder JE, Fish BL, Cohen EP, Lianos EA. 1999. TGF-beta 1 production in radiation nephropathy: role of angiotensin II. International Journal of Radiation Biology 75:473–479.
   PubMed Web of Science ®Google Scholar
• Dawson LA, Normolle D, Balter JM, McGinn CJ, Lawrence TS, Ten Haken RK. 2002. Analysis of radiation-induced liver disease using the Lyman NTCP model. International Journal of Radiation Oncology Biology Physics 53:810–821.
   PubMed Web of Science ®Google Scholar
• Eames GM, Crosson J, Steinberger J, Steinbuch M, Krabill K, Bass J, Ramsay NK, Neglia JP. 1997. Cardiovascular function in children following bone marrow transplant: A cross-sectional study. Bone Marrow Transplantation 19:61–66.
   PubMedGoogle Scholar
• Eric Jensen DVM, Fajardo LF, Stewart JR. 1970. Experimental radiation-induced heart disease. I. Light microscopic studies. American Journal of Pathology 59:299–316.
   PubMedGoogle Scholar
• Feurgard C, Bayle D, Guezingar F, Serougne C, Mazur A, Lutton C, Aigueperse J, Gourmelon P, Mathe D. 1998. Effects of ionizing radiation (neutrons/gamma rays) on plasma lipids and lipoproteins in rats. Radiation Research 150:43–51.
   PubMed Web of Science ®Google Scholar
• Geraci JP, Mariano MS. 1993. Radiation hepatology of the rat: Parenchymal and non-parenchymal cell injury. Radiation Research 136:205–213.
   PubMedGoogle Scholar
• Geraci JP, Mariano MS, Jackson KL, Taylor DA, Still ER. 1992. Effects of dexamethasone on late radiation injury following partial-body and local organ exposures. Radiation Research 129:61–70.
   PubMed Web of Science ®Google Scholar
• Gould RG, Bell VL, Lilly EH. 1959. Stimulation of cholesterol biosynthesis from acetate in rat liver and adrenals by whole body x-irradiation. American Journal of Physiology 196:1231–1237.
   PubMedGoogle Scholar
• Helfand I, Forrow L, Tiwari J. 2002. Nuclear terrorism. British Medical Journal 324:356–359.
   PubMed Web of Science ®Google Scholar
• Hooning MJ, Botma A, Aleman BM, Baaijens MH, Bartelink H, Klijn JG, Taylor CW, van Leeuwen FE. 2007. Long-term risk of cardiovascular disease in 10-year survivors of breast cancer. Journal of the National Cancer Institute 99:365–375.
   PubMedGoogle Scholar
• Karau KL, Molthen RC, Dhyani A, Haworth ST, Hanger CC, Roerig DL, Johnson RH, Dawson CA. 2001. Pulmonary arterial morphometry from microfocal X-ray computed tomography. American Journal of Physiology: Heart and Circulatory Physiology 281:H2747–2756.
   Google Scholar
• Lauk S. 1986. Strain differences in the radiation response of the rat heart. Radiotherapy and Oncology 5:333–335.
   PubMedGoogle Scholar
• Lauk S. 1987. Endothelial alkaline phosphatase activity loss as an early stage in the development of radiation-induced heart disease in rats. Radiation Research 110:118.
   PubMed Web of Science ®Google Scholar
• Lauk S, Kiszel Z, Buschmann J, Trott KR. 1985. Radiation-induced heart disease in rats. International Journal of Radiation Oncology Biology Physics 11:801–808.
   PubMed Web of Science ®Google Scholar
• McGale P, Darby SC. 2005. Low doses of ionizing radiation and circulatory diseases: A systematic review of the published epidemiological evidence. Radiation Research 163:247–257.
   PubMed Web of Science ®Google Scholar
• Migrino RQ, Zhu X, Pajewski N, Brahmbhatt T, Hoffmann R, Zhao M. 2007. Assessment of segmental myocardial viability using regional 2-dimensional strain echocardiography. Journal of the American Society of Echocardiography 20:342–351.
   PubMed Web of Science ®Google Scholar
• Moulder JE, Fish BL. 1989. Late toxicity of total body irradiation with bone marrow transplantation in a rat model. International Journal of Radiation Oncology Biology Physics 16:1501–1509.
   PubMed Web of Science ®Google Scholar
• Moulder JE, Fish BL, Cohen EP. 2004. Impact of angiotensin II type 2 receptor blockade on experimental radiation nephropathy. Radiation Research 161:312–317.
   PubMedGoogle Scholar
• Moulder JE, Fish BL, Holcenberg JS, Sun GX. 1990. Hepatic function and drug pharmacokinetics after total body irradiation plus bone marrow transplant. International Journal of Radiation Oncology Biology Physics 19:1389–1396.
   PubMed Web of Science ®Google Scholar
• Pihkala J, Saarinen UM, Lundstrom U, Salmo M, Virkola K, Virtanen K, Siimes MA, Pesonen E. 1994. Effects of bone marrow transplantation on myocardial function in children. Bone Marrow Transplantation 13:149–155.
   PubMed Web of Science ®Google Scholar
• Preston DL, Shimizu Y, Pierce DA, Suyama A, Mabuchi K. 2003. Studies of mortality of atomic bomb survivors. Report 13: Solid cancer and non-cancer disease mortality: 1950–1997. Radiation Research 160:381–407.
   PubMed Web of Science ®Google Scholar
• Shankar SM, Marina N, Hudson MM, Hodgson DC, Adams MJ, Landier W, Bhatia S, Meeske K, Chen MH, Kinahan KE, Steinberger J, Rosenthal D. 2008. Monitoring for cardiovascular disease in survivors of childhood cancer: report from the Cardiovascular Disease Task Force of the Children's Oncology Group. Pediatrics 121:e387–396.
   PubMed Web of Science ®Google Scholar
• Shelley RN. 1966. The effect of ionizing radiations on cholesterol levels of adrenals, liver, and plasma. Radiation Research 29:608–613.
   PubMed Web of Science ®Google Scholar
• Shi Y, Hutchins W, Ogawa H, Chang C-C, Pritchard K Jr, Zhang C, Khampang P, Lazar J, Jacob HJ, Rafiee P, Baker JE. 2005. Increased resistance to myocardial ischemia in the Brown Norway vs. Dahl S rat: Role of nitric oxide synthase and Hsp90. Journal of Molecular Cell Cardiology 38:625–635.
   PubMedGoogle Scholar
• Strande J, Hsu A, Su J, Fu X, Gross G, Baker JE. 2007. SCH 79797, a selective PAR-1 antagonist, limits myocardial ischemia-reperfusion injury in rat hearts. Basic Research in Cardiology 102:350–358.
   PubMed Web of Science ®Google Scholar
• Swerdlow AJ, Higgins CD, Smith P, Cunningham D, Hancock BW, Horwich A, Hoskin PJ, Lister A, Radford JA, Rohatiner AZ, Linch DC. 2007. Myocardial infarction mortality risk after treatment for Hodgkin disease: a collaborative British cohort study. Journal of the National Cancer Institute 99:206–214.
   PubMed Web of Science ®Google Scholar
• Verheij M, Dewit LG, van Mourik JA. 1995. The effect of ionizing radiation on endothelial tissue factor activity and its cellular localization. Thrombosis and Haemostasis 73:894–895.
   PubMedGoogle Scholar
• Wang J, Boerma M, Fu Q, Hauer-Jensen M. 2007. Significance of endothelial dysfunction in the pathogenesis of early and delayed radiation enteropathy. World Journal of Gastroenterology 13:3047–3055.
   PubMed Web of Science ®Google Scholar
• Wheeler DC, Bernard DB. 1994. Lipid abnormalities in the nephrotic syndrome: Causes, consequences, and treatment. American Journal of Kidney Diseases 23:331–346.
   PubMed Web of Science ®Google Scholar
• Wondergem J, van der Laarse A, van Ravels FJ, van Wermeskerken AM, Verhoeve HR, de Graaf BW, Leer JW. 1991. In vitro assessment of cardiac performance after irradiation using an isolated working rat heart preparation. International Journal of Radiation Biology 59:1053–1068.
   PubMed Web of Science ®Google Scholar
• Yamada M, Wong FL, Fujiwara S, Akahoshi M, Suzuki G. 2004. Non-cancer disease incidence in atomic bomb survivors, 1958–1998. Radiation Research 161:622–632.
   PubMed Web of Science ®Google Scholar
• Yeung TK, Hopewell JW. 1985. Effects of single doses of radiation on cardiac function in the rat. Radiotherapy and Oncology 3:339–345.
   PubMed Web of Science ®Google Scholar
• Yeung TK, Lauk S, Simmonds RH, Hopewell JW, Trott KR. 1989. Morphological and functional changes in the rat heart after X irradiation: Strain differences. Radiation Research 119:489–499.
   PubMed Web of Science ®Google Scholar