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Bystander Effects in 3D Human Skin Model

Development of a method for assessing non-targeted radiation damage in an artificial 3D human skin model

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Pages 593-601 | Received 16 Jul 2009, Accepted 12 Feb 2010, Published online: 15 Jun 2010

References

  • Azzam EI, de Toledo SM, Little JB. 2001. Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from α-particle irradiated to non-irradiated cells. Proceedings of the National Academy of Science of the USA 98:473–478.
  • Belyakov OV, Folkard M, Mothersill C, Prise KM, Michael BD. 2003. A proliferation-dependent bystander effect in primary porcine and human urothelial explants in response to targeted irradiation. British Journal of Cancer 88:767–774.
  • Belyakov OV, Mitchell SA, Parikh D, Randers-Pehrson G, Marino SA, Amundson SA, Geard CR, Brenner DJ. 2005. Biological effects in unirradiated human tissue induced by radiation damage up to 1 mm away. Proceedings of the National Academy of Science of the USA 102:14203–14208.
  • Bird RP, Rohrig N, Colvett RD, Geard CR, Marino SA. 1980. Inactivation of synchronized Chinese Hamster V79 cells with charged-particle track segments. Radiation Research 82:277–289.
  • Chen S, Zhao Y, Han W, Zhao G, Zhu L, Wang J, Bao L, Jiang E, Xu A, Hei TK, Yu Z, Wu L. 2008. Mitochondria-dependent signalling pathways are involved in the early process of radiation-induced bystander effects. British Journal of Cancer 98:1839–1844.
  • Curren RD, Mun GC, Gibson DP, Aardema MJ. 2006. Development of a method for assessing micronucleus induction in a 3D human skin model (EpiDerm). Mutation Research 607:192–204.
  • Fenech M. 2000. The in vitro micronucleus technique. Mutation Research 455:81–95.
  • Hybbinette S, Bostrom M, Lindberg K. 1999. Enzymatic dissociation of keratinocytes from human skin biopsies for in vitro cell propagation. Experimental Dermatology 8:30–38.
  • Iyer R, Lehnert BE. 2000. Factors underlying the cell growth-related bystander responses to alpha-particles. Cancer Research 60:1290–1298.
  • Monteiro-Riviere NA, Inman AO, Snider TH, Blank JA, Hobson DW. 1997. Comparison of an in vitro skin model to normal human skin for dermatological research. Microscopical Research and Technology 37:172–179.
  • Morgan WF, Sowa MB. 2007. Non-targeted bystander effects induced by ionizing radiation. Mutation Research 616:159–164.
  • Netzlaff F, Lehr CM, Wertz PW, Schaefer UF. 2005. The human epidermis models EpiSkin, SkinEthic and EpiDerm: An evaluation of morphology and their suitability for testing phototoxicity, irritancy, corrosivity, and substance transport. European Journal of Pharmaceutics and Biopharmaceutics 60:167–178.
  • Ponec M, Boelsma E, Gibbs S, Mommaas M. 2002. Characterization of reconstructed skin models. Skin Pharmacology and Applied Skin Physiology 15(Suppl. 1):4–17.
  • Prise KM, Belyakov OV, Folkard M, Michael BD. 1998. Studies of bystander effects in human fibroblasts using a charged particle microbeam. International Journal of Radiation Biology 74:793–798.
  • Shao C, Stewart V, Folkard M, Michael BD, Prise KM. 2003. Nitric oxide-mediated signalling on the bystander response of individually targeted glioma cells. Cancer Research 63:8437–8442.
  • Tartier L, Gilchrist S, Folkard M, Prise KM. 2007. Cytoplasmic irradiation induces 53BP1 protein recolization in irradiated and bystander cells. Cancer Research 67:5872–5879.
  • Zhao JF, Zhang YJ, Kubilus J, Jin XH, Santella RM, Athar M, Wang ZY, Bickers DR. 1999. Reconstituted 3-dimensional human skin as a novel in vitro model for studies of carcinogenesis. Biochemical and Biophysical Research Communications 254:49–53.

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