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Radioactive Iodine and Asymmetric Dimetilarginin

The alteration of asymmetric dimetilarginine (ADMA) levels in cardiac and gastrocnemius muscles following radioactive iodine application in guinea pigs and the effect of L-carnitine on this alteration

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Pages 2-7 | Received 18 Dec 2009, Accepted 16 Jul 2010, Published online: 28 Oct 2010

References

  • Altas E, Ertekin MV, Gundogdu C, Demirci E. 2006. L-carnitine reduces cochlear damage induced by gamma irradiation in Guinea pigs. Annals of Clinical and Laboratory Science 36:312–318.
  • Baker JE, Fish BL, Su J, Haworth ST, Strande JL, Komorowski RA, Migrino RQ, Doppalapudi A, Harmann L, Allen Li X, Hopewell JW, Moulder JE. 2009. 10 Gy total body irradiation increases risk of coronary sclerosis, degeneration of heart structure and function in a rat model. International Journal of Radiation Biology 85:1098–1100.
  • Baskol G, Atmaca H, Tanriverdi F, Baskol M, Kocer D, Bayram F. 2007. Oxidative stress and enzymatic antioxidant status in patients with hypothyroidism before and after treatment. Experimental and Clinical Endocrinology and Diabetes 115:522–526.
  • Beltowski J, Kedra A. 2006. Asymmetric dimethylarginine (ADMA) as a target for pharmacotherapy. Pharmacological Reports 58:159–178.
  • Boger RH, Sullivan LM, Schwedhelm E, Wang TJ, Maas R, Benjamin EJ, Schulze F, Xanthakis V, Benndorf RA, Vasan RS. 2009. Plasma asymmetric dimethylarginine and incidence of cardiovascular disease and death in the community. Circulation 119:1592–1600.
  • Caloglu M, Yurut-Caloglu V, Durmus-Altun G, Oz-Puyan F, Ustun F, Cosar-Alas R, Saynak M, Parlar S, Turan FN, Uzal C. 2009. Histopathological and scintigraphic comparisons of the protective effects of L-carnitine and amifostine against radiation-induced late renal toxicity in rats. Clinical Experimental Pharmacology Physiology 36:523–530.
  • Chow S. 2005. Side effects of high-dose radioactive iodine for ablation or treatment of differentiated thyroid carcinoma. JHK Collage of Radiology 8:127–135.
  • Closs EI, Basha FZ, Habermeier A, Forstermann U. 1997. Interference of L-arginine analogues with L-arginine transport mediated by the y+ carrier hCAT-2B. Nitric Oxide 1:65–73.
  • Coria MJ, Pastran AI, Gimenez MS. 2009. Serum oxidative stress parameters of women with hypothyroidism. Acta Biomedica 80:135–139.
  • Erdamar H, Demirci H, Yaman H, Erbil MK, Yakar T, Sancak B, Elbeg S, Biberoglu G, Yetkin I. 2008. The effect of hypothyroidism, hyperthyroidism, and their treatment on parameters of oxidative stress and antioxidant status. Clinical Chemistry and Laboratory Medicine 46:1004–1010.
  • Fortier C, Schindler WJ. 1962. Effect of pretreatment with thyroxin on the uptake and synthesis of radioactive iodine by incubated segments of the guinea pig thyroid. Laval Medical 33:507–515.
  • Franklyn JA, Sheppard MC, Maisonneuve P. 2005. Thyroid function and mortality in patients treated for hyperthyroidism. Journal of the American Medical Association 294:71–80.
  • Fregly MJ, Gennaro JF Jr, Otis AB. 1960. Effect of treatment with radioactive iodine and iodine-deficient diet on development and maintenance of renal hypertension in rats. Circulation Research 8:749–758.
  • Georges B, Le Borgne F, Galland S, Isoir M, Ecosse D, Grand-Jean F, Demarquoy J. 2000. Carnitine transport into muscular cells. Inhibition of transport and cell growth by mildronate. Biochemical Pharmacology 59:1357–1363.
  • Hall P, Berg G, Bjelkengren G, Boice JD Jr, Ericsson UB, Hallquist A, Lidberg M, Lundell G, Tennvall J, Wiklund K. 1992. Cancer mortality after iodine-131 therapy for hyperthyroidism. International Journal of Cancer 50:886–890.
  • Lajer M, Tarnow L, Jorsal A, Teerlink T, Parving HH, Rossing P. 2008. Plasma concentration of asymmetric dimethylarginine (ADMA) predicts cardiovascular morbidity and mortality in type 1 diabetic patients with diabetic nephropathy. Diabetes Care 31:747–752.
  • Lowry OH, Rosebrouugh NJ, Farr AL, Randall RJ. 1951. Protein measurement with the folin phenol reagent. Journal of Biological Chemistry 193:265–275.
  • Mansour HH. 2006. Protective role of carnitine ester against radiation-induced oxidative stress in rats. Pharmacological Research 54:165–171.
  • Metso S, Auvinen A, Salmi J, Huhtala H, Jaatinen P. 2008. Increased long-term cardiovascular morbidity among patients treated with radioactive iodine for hyperthyroidism. Clinical Endocrinology 68:450–457.
  • Metso S, Jaatinen P, Huhtala H, Auvinen A, Oksala H, Salmi J. 2007. Increased cardiovascular and cancer mortality after radioiodine treatment for hyperthyroidism. Journal of Clinical Endocrinology and Metabolism 92:2190–2196.
  • Ozcan O, Cakir E, Yaman H, Akgul EO, Erturk K, Beyhan Z, Bilgi C, Erbil MK. 2005. The effects of thyroxine replacement on the levels of serum asymmetric dimethylarginine (ADMA) and other biochemical cardiovascular risk markers in patients with subclinical hypothyroidism. Clinical Endocrinology 63:203–206.
  • Quesada A, Sainz J, Wangensteen R, Rodriguez-Gomez I, Vargas F, Osuna A. 2002. Nitric oxide synthase activity in hyperthyroid and hypothyroid rats. European Journal of Endocrinology 147:117–122.
  • Rigault C, Dias JV, Demarquoy J, Le Borgne F. 2008. Characteristics of L-carnitine import into heart cells. Biochimie 90:542–546.
  • Rodemann HP, Blaese MA. 2007. Responses of normal cells to ionizing radiation. Seminars in Radiation Oncology 17:81–88.
  • Santini MT, Bonincontro A, Cametti C, Treccosti P, Indovina PL. 1990. Dose-dependent effects of ionizing radiation on in vitro myoblast fusion. International Journal of Radiation Biology 58:463–474.
  • Sezen O, Ertekin MV, Demircan B, Karslioglu I, Erdogan F, Kocer I, Calik I, Gepdiremen A. 2008. Vitamin E and L-carnitine, separately or in combination, in the prevention of radiation-induced brain and retinal damages. Neurosurgical Review 31:205–213.
  • Suda O, Tsutsui M, Morishita T, Tasaki H, Ueno S, Nakata S, Tsujimoto T, Toyohira Y, Hayashida Y, Sasaguri Y, Ueta Y, Nakashima Y, Yanagihara N. 2004. Asymmetric dimethylarginine produces vascular lesions in endothelial nitric oxide synthase-deficient mice: Involvement of renin-angiotensin system and oxidative stress. ArteriosclerosisThrombosis and Vascular Biology 24:1682–1688.
  • Teerlink T, Nijveldt RJ, de Jong S, van Leeuwen PA. 2002. Determination of arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in human plasma and other biological samples by high-performance liquid chromatography. Analytical Biochemistry 303:131–137.
  • Topcu-Tarladacalisir Y, Kanter M, Uzal MC. 2009. Role of L-carnitine in the prevention of seminiferous tubules damage induced by gamma radiation: A light and electron microscopic study. Archives of Toxicology 83:735–746.
  • Turgut B, Babul A, Ozdemir O, Erselcan T. 2006a. Evaluation of the cell death pathway and apoptosis-stunning effect relationship after low- and high-dose I-131 administrations in rat thyroid tissue. Cancer Biotherapy and Radiopharmaceuticals 21:342–351.
  • Turgut B, Ozdemir O, Erselcan T. 2006b. Evaluation of the p53 tumour suppressor gene mutation in normal rat salivary gland tissue after radioiodine application: An experimental study. Advences in Therapy 23:456–468.
  • Ucuncu H, Ertekin MV, Yoruk O, Sezen O, Ozkan A, Erdogan F, Kiziltunc A, Gundogdu C. 2006. Vitamin E and L-carnitine, separately or in combination, in the prevention of radiation-induced oral mucositis and myelosuppression: A controlled study in a rat model. Journal of Radiation Research 47:91–102.
  • Vanella A, Russo A, Acquaviva R, Campisi A, Di Giacomo C, Sorrenti V, Barcellona ML. 2000. L -propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protector. Cell Biology and Toxicology 16:99–104.
  • Weber M, Lauer N, Mulsch A, Kojda G. 2001. The effect of peroxynitrite on the catalytic activity of soluble guanylyl cyclase. Free Radical Biology and Medicine 31:1360–1367.
  • Wilson Tang WH, Tong W, Shrestha K, Wang Z, Levison BS, Delfraino B, Hu B, Troughton RW, Klein AL, Hazen SL. 2008. Differential effects of arginine methylation on diastolic dysfunction and disease progression in patients with chronic systolic heart failure. European Heart Journal 29:2506–2513.

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