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Prediction of Radiation Induced Late Toxicity

Role of CD4 and CD8 T-lymphocytes, B-lymphocytes and Natural Killer cells in the prediction of radiation-induced late toxicity in cervical cancer patients

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Pages 424-431 | Received 20 May 2010, Accepted 24 Oct 2010, Published online: 10 Dec 2010

References

  • Bentzen SM, Overgaard J. 1994. Patient-to-patient variability in the expression of radiation-induced normal tissue injury. Seminars in Radiation Oncology 4:68–80.
  • Bohm L. 2007. New trends in the management of late radiation morbidity. International Journal of Low Radiation 4:332–335.
  • Bordón E, Henríquez-Hernández LA, Lara PC, Pinar B, Fontes F, Rodríguez Gallego C, Lloret M. 2009. Prediction of clinical toxicity in localized cervical carcinoma by radio-induced apoptosis study in peripheral blood lymphocytes (PBLs). Radiation Oncology 4:58.
  • Bordón E, Henríquez-Hernández LA, Lara PC, Ruiz A, Pinar B, Rodríguez Gallego C, Lloret M. 2010. Prediction of clinical toxicity in locally advanced head and neck cancer patients by radio-induced apoptosis in peripheral blood lymphocytes (PBLs). Radiation Oncology 5:4.
  • Buchholz TA. 1999. Finding our sensitive patients. International Journal of Radiation Oncology, Biology, Physics 45:547–548.
  • Defrance T, Casamayor-Palleja M, Krammer PH. 2002. The life and death of a B cell. Advances in Cancer Research 86:195–225.
  • Denny T, Yogev R, Gelman R, Skuza C, Oleske J, Chadwick E, Cheng SC, Connor E. 1992. Lymphocyte subsets in healthy children during the first 5 years of life. Journal of the American Medical Association 267:1484–1488.
  • Duchaud E, Ridet A, Delic Y, Cundari E, Moustacchi E, Rosselli F. 1994. Changes in the radiation-induced apoptotic response in homozygotes and heterozygotes for the ataxia-telangiectasia gene. Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 317:983–989.
  • Emami B, Lyman J, Brown A, Coia L, Goitein M, Munzenrider JE, Shank B, Solin LJ, Wesson M. 1991. Tolerance of normal tissue to therapeutic irradiation. International Journal of Radiation Oncology, Biology, Physics 21:109–122.
  • Fernet M, Hall J. 2008. Predictive markers for normal tissue reactions: Fantasy or reality? Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique 12:614–618.
  • Floyd DN, Cassoni AM. 1994. Intrinsic radiosensitivity of adult and cord blood lymphocytes as determined by the micronucleus assay. European Journal of Cancer 30A:615–620.
  • Henríquez-Hernández LA, Lara PC, Pinar B, Bordón E, Rodríguez Gallego C, Bilbao C, Fernandez Perez L, Flores Morales A. 2009. Constitutive gene expression profile segregates toxicity in locally advanced breast cancer patients treated with high-dose hyperfractionated radical radiotherapy. Radiation Oncology 4:17.
  • Jones LA, Scott D, Cowan R, Roberts SA. 1995. Abnormal radiosensitivity of lymphocytes from breast cancer patients with excessive normal tissue damage after radiotherapy: Chromosome aberrations after low dose-rate irradiation. International Journal of Radiation Biology 67:519–528.
  • Kiltie AE, Ryan AJ, Swindell R, Barber JB, West CM, Magee B, Hendry JH. 1999. A correlation between residual radiation-induced DNA double-strand breaks in cultured fibroblasts and late radiotherapy reactions in breast cancer patients. Radiotherapy and Oncology 51:55–65.
  • Louagie H, Van Eijkeren M, Philippe J, Thierens H, de Ridder L. 1999. Changes in peripheral blood lymphocyte subsets in patients undergoing radiotherapy. International Journal of Radiation Biology 75:767–771.
  • Meyn MS. 1995. Ataxia-telangiectasia and cellular responses to DNA damage. Cancer Research 55:5991–6001.
  • Mori M, Benotmane MA, Tirone I, Hooghe-Peters EL, Desaintes C. 2005. Transcriptional response to ionizing radiation in lymphocyte subsets. Cellular and Molecular Life Sciences 62:1489–1501.
  • Muller C, Dusseau C, Calsou P, Salles B. 1998. Human normal peripheral blood B-lymphocytes are deficient in DNA-dependent protein kinase activity due to the expression of a variant form of the Ku86 protein. Oncogene 16:1553–1560.
  • Ozsahin M, Crompton NE, Gourgou S, Kramar A, Li L, Shi Y, Sozzi WJ, Zouhair A, Mirimanoff RO, Azria D. 2005. CD4 and CD8 T-lymphocyte apoptosis can predict radiation-induced late toxicity: A prospective study in 399 patients. Clinical Cancer Research 11:7426–7433.
  • Ozsahin M, Ozsahin H, Shi Y, Larsson B, Wurgler FE, Crompton NE. 1997. Rapid assay of intrinsic radiosensitivity based on apoptosis in human CD4 and CD8 T-lymphocytes. International Journal of Radiation Oncology, Biology, Physics 38:429–440.
  • Pavy JJ, Denekamp J, Letschert J, Littbrand B, Mornex F, Bernier J, Gonzales-Gonzales D, Horiot JC, Bolla M, Bartelink H. 1995. EORTC Late Effects Working Group. Late Effects toxicity scoring: The SOMA scale. International Journal of Radiation Oncology, Biology, Physics 31:1043–1047.
  • Philippe J, Louagie H, Thierens H, Vral A, Cornelissen M, De Ridder L. 1997. Quantification of apoptosis in lymphocyte subsets and effect of apoptosis on apparent expression of membrane antigens. Cytometry 29:242–249.
  • Radford IR, Murphy TK. 1994. Radiation response of mouse lymphoid and myeloid cell lines. Part III. Different signals can lead to apoptosis and may influence sensitivity to killing by DNA double-strand breakage. International Journal of Radiation Biology 65:229–239.
  • Reichert T, DeBruyere M, Deneys V, Totterman T, Lydyard P, Yuksel F, Chapel H, Jewell D, Van Hove L, Linden J, et al. 1991. Lymphocyte subset reference ranges in adult Caucasians. Clinical Immunology and Immunopathology 60:190–208.
  • Rodningen OK, Borresen-Dale AL, Alsner J, Hastie T, Overgaard J. 2008. Radiation-induced gene expression in human subcutaneous fibroblasts is predictive of radiation-induced fibrosis. Radiotherapy and Oncology 86:314–320.
  • Rosselli F, Ridet A, Soussi T, Duchaud E, Alapetite C, Moustacchi E. 1995. p53-dependent pathway of radio-induced apoptosis is altered in Fanconi anemia. Oncogene 10:9–17.
  • Schmitz A, Bayer J, Dechamps N, Thomas G. 2003. Intrinsic susceptibility to radiation-induced apoptosis of human lymphocyte subpopulations. International Journal of Radiation Oncology, Biology, Physics 57:769–778.
  • Schneider P, Tschopp J. 2003. BAFF and the regulation of B cell survival. Immunology Letters 88:57–62.
  • Seki H, Iwai K, Kanegane H, Konno A, Ohta K, Yachie A, Taniguchi N, Miyawaki T. 1995. Differential protective action of cytokines on radiation-induced apoptosis of peripheral lymphocyte subpopulations. Cellular Immunology 163:30–36.
  • Seki H, Kanegane H, Iwai K, Konno A, Ohta K, Yachie A, Taniguchi N, Miyawaki T. 1994. Ionizing radiation induces apoptotic cell death in human TcR-gamma/delta+ T and natural killer cells without detectable p53 protein. European Journal of Immunology 24:2914–2917.
  • Stankeova S, Crompton NE, Blattmann H, Theiler P, Emery GC, Roos M, Kaser-Hotz B. 2003. Apoptotic response of irradiated T-lymphocytes. An epidemiologic study in canine radiotherapy patients. Strahlentherapie und Onkologie 179:779–786.
  • Stewart CC, Stevenson AP, Habbersett RC. 1988. The effect of low-dose irradiation on unstimulated and PHA-stimulated human lymphocyte subsets. International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine 53:77–87.
  • West CM, Hendry JH, Scott D, Davidson SE, Hunter RD. 1991. 25th Paterson Symposium – is there a future for radiosensitivity testing? British Journal of Cancer 64:197–199.

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