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ORIGINAL ARTICLE

Assessing patient characteristics and radiation-induced non-targeted effects in vivo for high dose-rate (HDR) brachytherapy

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Pages 786-794 | Received 18 Dec 2014, Accepted 27 Jun 2015, Published online: 18 Sep 2015

References

  • Ahmad SB, McNeill FE, Byun SH, Prestwich WV, Mothersill C, Seymour C, Armstrong A, Fernandez C. 2013. Ultra-violet light emission from HPV-G cells irradiated with low let radiation from (90)Y; consequences for radiation induced bystander effects. Dose-Response 11:498:–Res
  • Berry B, Miller RR, Luoma A, Nelems B, Hay J, Flores AD. 1989. Pathologic findings in total esophagectomy specimens after intracavitary and external-beam radiotherapy. Cancer 64:1833–1837.
  • Boyden S, Raaphorst GP. 1999. Adaptive response and its variation in human normal and tumour cells. Int J Radiat Biol 75:865–873.
  • Boyd M, Sorensen A, McCluskey AG, Mairs RJ. 2008. Radiation quality-dependent bystander effects elicited by targeted radionuclides. J Pharm Pharmacol 60:951–958.
  • Brenner DJ, Curtis RE, Hall EJ, Ron E. 2000. Second malignancies in prostate carcinoma patients after radiotherapy compared with surgery. Cancer 88:398–406.
  • Butterworth KT, McMahon SJ, Hounsell AR, O’Sullivan JM, Prise KM. 2013. Bystander signalling: Exploring clinical relevance through new approaches and new models. Clin Oncol 25:586–592.
  • Chai Y, Hei TK. 2008. Radiation induced bystander effect in vivo. Acta Med Nagasaki 53:S65–S69.
  • Chiou CC, Groll AH, Walsh TJ. 2000. New drugs and novel targets for treatment of invasive fungal infections in patients with cancer. Oncologist 5:120–135.
  • Delsing CE, Bleeker-Rovers CP, van de Veerdonk FL, Tol J, Van der Meer JWM, Kullberg BJ, Netea MG. 2012. Association of esophageal candidiasis and squamous cell carcinoma. Med Mycol 1:5–8.
  • Emerit I, Levy A, Cernjavski L, Arutyunyan R, Oganesyan N, Pogosian A, Mejlumian H, Sarkisian T, Gulkandanian M, Quastel M. 1994. Transferable clastogenic activity in plasma from persons exposed as salvage personnel of the Chernobyl reactor. J Cancer Res Clin Oncol 120:558–561.
  • Emerit I, Oganesian N, Sarkisian T, Arutyunyan R, Pogosian A, Asrian K, Levy A, Cernjavski L. 1995. Clastogenic factors in the plasma of Chernobyl accident recovery workers: Anticlastogenic effect of Ginkgo biloba extract. Radiat Res 144:198–205.
  • Emerit I, Quastel M, Goldsmith J, Merkin L, Levy A, Cernjavski L, Alaoui-Youssefi A, Pogossian A, Riklis E. 1997. Clastogenic factors in the plasma of children exposed at Chernobyl. Mutat Res 373: 47–54.
  • Faguet GB, Reichard SM, Welter DA. 1984. Radiation-induced clastogenic plasma factors. Cancer Genet Cytogenet 12:73–83.
  • Faul F, Erdfelder E, Lang AG, Buchner A. 2007. G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39:175–191.
  • Fukasawa M, Bryant SM, DiZerega GS. 1988. Superoxide anion production by postsurgical macrophages. J Surg Res 45:382–388.
  • Goh K, Sumner H. 1968. Breaks in normal human chromosomes: Are they induced by a transferable substance in the plasma of persons exposed to total-body irradiation? Radiat Res 35:171–181.
  • Hall EJ, Wuu CS. 2003. Radiation-induced second cancers: The impact of 3D-CRT and IMRT. Int J Radiat Oncol Biol Phys 56:83–88.
  • Hollowell JG Jr, Littlefield LG. 1968. Chromosome damage induced by plasma of x-rayed patients: An indirect effect of x-ray. Proc Soc Exp Biol Med 129:240–244.
  • Howe O, O’Sullivan J, Nolan B, Vaughan J, Gorman S, Clarke C, McClean B, Lyng FM. 2009. Do radiation-induced bystander effects correlate to the intrinsic radiosensitivity of individuals and have clinical significance? Radiat Res 171:521–529.
  • Johnston JR, Godzik C, Cohn Z. 1978. Increased superoxide anion production by immunologically activated and chemically elicited macrophages. J Exp Med 148:115–129.
  • Koturbash I, Kutanzi K, Hendrickson K, Rodriguez-Juarez R, Kogosov D, Kovalchuk O. 2008. Radiation-induced bystander effects in vivo are sex specific. Mutat Res 642:28–36.
  • Lorimore SA, Coates PJ, Scobie GE, Milne G, Wright EG. 2001. Inflammatory-type responses after exposure to ionizing radiation in vivo: A mechanism for radiation-induced bystander effects? Oncogene 20:7085–7095.
  • Lyng FM, Maguire P, McClean B, Seymour C, Mothersill C. 2006. The involvement of calcium and MAP kinase signaling pathways in the production of radiation-induced bystander effects. Radiat Res 165:4005:at.
  • Lyng FM, Seymour CB, Mothersill C. 2000. Production of a signal by irradiated cells which leads to a response in unirradiated cells characteristic of initiation of apoptosis. Br J Cancer 83:1223–1230.
  • Maguire P, Mothersill C, McClean B, Seymour CB, Lyng FM. 2007. Modulation of radiation responses by pre-exposure to irradiated cell conditioned medium. Radiat Res 167:485–492.
  • Manda K., Glasow A, Paape D, Hildebrandt G. 2012. Effects of ionizing radiation on the immune system with special emphasis on the interaction of dendritic and T cells. Front Oncol 2:102.
  • Marozik P, Mothersill C, Seymour CB, Mosse I, Melnov S. 2007. Bystander effects induced by serum from survivors of the Chernobyl accident. Exp Hematol 35:55–63.
  • Michiels C. 2004. Physiological and pathological responses to hypoxia. Am J Pathol 164:1875–1882.
  • Mitchell JB, Bedford JS, Bailey SM. 1979. Dose-rate effects in plateau-phase cultures of S3 HeLa and V79 cells. Radiat Res 79:552–567.
  • Mohammadi S, Taghavi-Dehaghani M, Gharaati MR, Masoomi R, Ghiassi-Nejad M. 2006. Adaptive response of blood lymphocytes of inhabitants residing in high background radiation areas of ramsar- micronuclei, apoptosis and comet assays. J Radiat Res 47:279–285.
  • Morgan WF. 2003. Non-targeted and delayed effects of exposure to ionizing radiation: II. Radiation-induced genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects. Radiat Res 159:581–596.
  • Mothersill C. 2013. Uncomfortable issues in radiation protection posed by low-dose radiobiology. Radiat Environ Biophys 52:293–298.
  • Mothersill C, Moriarty M, Seymour C. 2004a. Radiotherapy and the potential exploitation of bystander effects. Int J Radiat Oncol Biol Phys 58:575–579.
  • Mothersill C, O’Malley K, Seymour CB. 2002. Characterisation of a bystander effect induced in human tissue explant cultures by low LET radiation. Radiat Prot Dosimetry 99:163–167.
  • Mothersill C, Rea D, Wright EG, Lorimore SA, Murphy D, Seymour CB, O’Malley K. 2001. Individual variation in the production of a ‘bystander signal’ following irradiation of primary cultures of normal human urothelium. Carcinogenesis 22:1465cinog
  • Mothersill C, Seymour CB. 2006. Radiation-induced bystander and other non-targeted effects: Novel intervention points in cancer therapy? Curr Cancer Drug Targets 6:447–454.
  • Mothersill C, Seymour C. 1997. Survival of human epithelial cells irradiated with cobalt 60 as microcolonies or single cells. Int J Radiat Biol 72:597–606.
  • Mothersill C, Seymour CB. 2004. Radiation-induced bystander effects – implications for cancer. Nat Rev Cancer 4:158–164.
  • Mothersill C, Seymour RJ, Seymour CB. 2004b. Bystander effects in repair-deficient cell lines. Radiat Res 161:256–263.
  • Multhoff G, Radons J. 2012. Radiation, inflammation, and immune responses in cancer. Front Oncol 2:58.
  • O’Dowd C, Mothersill CE, Cairns MT, Austin B, McClean B, Lyng FM, Murphy JEJ. 2006. The release of bystander factor(s) from tissue explant cultures of rainbow trout (Onchorhynchus mykiss) after exposure to gamma radiation. Radiat Res 166:611–617.
  • Pant GS, Kamada N. 1977. Chromosome aberrations in normal leukocytes induced by the plasma of exposed individuals. Hiroshima J Med Sci 26:149–154.
  • Pinho C, Wong R, Sur RK, Hayward JE, Farrell TJ, Seymour C, Mothersill C. 2012. The involvement of serum serotonin levels producing radiation-induced bystander effects for an in vivo assay with fractionated high dose-rate (HDR) brachytherapy. Int J Radiat Biol 88:791–797.
  • Pirisi L, Creek KE, Doniger J, Dipaolo JA. 1988. Continuous cell lines with altered growth and differentiation properties originate after transfection of human keratinocytes with human papillomavirus type 16 DNA. Carcinogenesis 9:1573–1579.
  • Prise KM, Belyakov OV, Folkard M, Michael BD. 1998. Studies of bystander effects in human fibroblasts using a charged particle microbeam. Int J Radiat Biol 74:793–798.
  • Prise KM, O’Sullivan JM. 2009. Radiation-induced bystander signalling in cancer therapy. Nat Rev Cancer 9:351–360.
  • Qutob SS, Multani AS, Pathak S, McNamee JP, Bellier PV, Liu QY, Ng CE. 2006. Fractionated X-radiation treatment can elicit an inducible-like radioprotective response that is not dependent on the intrinsic cellular X-radiation resistance/sensitivity. Radiat Res 166:590–599.
  • Rödel F, Frey B, Gaipl U, Keilholz L, Fournier C, Manda K, Schöllnberger H, Hildebrandt G, Rödel C. 2012. Modulation of inflammatory immune reactions by low-dose ionizing radiation: Molecular mechanisms and clinical application. Curr Med Chem 19:1741–1750.
  • Ryan LA, Seymour CB, Joiner MC, Mothersill CE. 2009. Radiation-induced adaptive response is not seen in cell lines showing a bystander effect but is seen in lines showing HRS/IRR response. Int J Radiat Biol 85:87–95.
  • Ryan LA, Smith RW, Seymour CB, Mothersill CE. 2008. Dilution of irradiated cell conditioned medium and the bystander effect. Radiat Res 169:188iat R
  • Seymour CB, Mothersill C. 2000. Relative contribution of bystander and targeted cell killing to the low-dose region of the radiation dose-response curve. Radiat Res 153:508–511.
  • Seymour C, Mothersill C. 2006. Development of an in vivo assay for detection of non-targeted radiation effects. Dose Response 4:277–282.
  • Sur RK, Donde B, Levin VC, Mannell A. 1998. Fractionated high dose rate intraluminal brachytherapy in palliation of advanced esophageal cancer. Int J Radiat Oncol Biol Phys 40:447–453.
  • Sur RK, Levin CV, Donde B, Sharma V. Miszczyk L, Nag S. 2002. Prospective randomized trial of HDR brachytherapy as a sole modality in palliation of advanced esophageal carcinoma–an International Atomic Energy Agency study. Int J Radiat Oncol Biol Phys 53: 127–133.
  • Thomas C, Martin J, Devic C, Bräuer-Krisch E, Diserbo M, Thariat J, Foray N. 2013. Impact of dose-rate on the low-dose hyper-radiosensitivity and induced radioresistance (HRS/IRR) response. Int J Radiat Biol 89:813–822.
  • Twardella D, Chang-Claude J. 2002. Studies on radiosensitivity from an epidemiological point of view – overview of methods and results. Radiother Oncol 62:249–260.
  • Yoshioka Y, Yoshida K, Yamazaki H, Nonomura N, Ogawa K. 2013. The emerging role of high-dose-rate (HDR) brachytherapy as monotherapy for prostate cancer. J Radiat Res 54:781–788.

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