References
- Abell DC, Sporns P. 1996. Rapid quantitation of potato glycoalkaloids by matrix assisted laser desorption/ionization time-of-flight mass spectrometry. J Agric Food Chem 44:2292–2296
- Bianco G, Schimitt-Kopplin P, Crescenzi A, Comes S, Kettrup A, Cataldi TRI. 2003. Evaluation of glycoalkaloids in tubers of genetically modified virus Y-resistant potato plants (var. Désirée) by non-aqueous capillary electrophoresis coupled with electrospray ionization mass spectrometry (NACE–ESI–MS). Anal Bioanal Chem 375:799–804
- Blankemeyer JT, Stringer BK, Rayburn JR, Bantle JA, Friedman M. 1992. Effect of potato alkaloids on membrane potential of frog embryos. J Agric Food Chem 40:2022–2025
- Blankemeyer JT, White JB, Stringer BK, Friedman M. 1997. Effect of α-tomatine and tomatidine on membrane potential of frog embryos and active transport of ions in frog skin. Food Chem Toxicol 35:639–646
- Blankemeyer JT, McWilliams ML, Rayburn JR, Weissenberg M, Friedman M. 1998. Developmental toxicology of solamargine and solasonine glycoalkaloids in frog embryos. Food Chem Toxicol 36:383–389
- Bushway AA, Bushway RJ, Kim CH. 1988. Isolation, partial purification and characterization of a potato peel a-solanine cleaving glycosidase. Am Potato J 67:233–238
- Cahill GM, Caprioli C, Vittori S, James KJ. 2010. Elucidation of the mass fragmentation pathway of potato glycoalkaloids and aglycons using Orbitrap mass spectrometry. J Mass Spectrom 45:1019–1025
- Caprioli C, Cahill GM, James KJ. 2014a. Mass fragmentation studies of α-tomatine and validation of a liquid chromatography LTQ-Orbitrap Mass Spectrometry Method for its quantification in Tomatoes. Food Anal Met. 7:1565–1571
- Caprioli C, Cahill GM, Vittori S, James KJ. 2014b. Liquid chromatography –hybrid linear ion trap-high resolution mass spectrometry (LTQ-Orbitrap) method for the determination of glycoalkaloids and their aglycons in potato samples. Food Anal Met 7:1367–1372
- Cherkaoui S, Bekkouche K, Christen P, Veuthey JL. 2001. Non-acqueous capillary electrophoresis with diode array and electrospray mass spectrometric detection for the analysis of selected steroidal alkaloids in plant extracts. J Chromatogr A 992:321–328
- Claringbold WDB, Few JD, Renwick J. 1982. Kinetics of retention of solanidine in man. Xenobiotica 12:293–302
- Dall’Asta C, Falavigna C, Galaverna G, Sforza S, Dossena A, Marchelli R. 2009. A multiresidual method for the simultaneous determination of the main glycoalkaloids and flavonoids in fresh and processed tomato (Solanum lycopersicum L.) by LC-DAD-MS/MS. J Sep Sci 32:3664–3671
- Dixit VP, Gupta RS, Gupta S. 1989. Antifertility plant products: testicular cell population dynamics following solasodine administration in rhesus monkeys (Macca mulatta). Andrologia 21:542–546
- Driedger DR, LeBlanc RJ, LeBlanc E, Sporns P. 2000. A capillary electrophoresis laser-induced fluorescence method for analysis of potato glycoalkaloids based on a solution-phase immunoassay. 1. Separation and quantification of immunoassay products. J Agric Food Chem 48:1135–1139
- Duan GM. 1994. Inibition of potato glycoalkaloids to human blood cholinesterase. Chin Biochem J 10:575–578
- Friedman M, Levin CE. 1995. Tomatine content in tomato and tomato products determined by HPLC with pulsed amperometric detection. J Agric Food Chem 43:1507–1511
- Friedman M, Henika PR, Mackey BE. 1996. Feeding potato, tomato, and eggplant alkaloids affects food consumption and body and liver weights of mice. J Nutr 126:989–999
- Friedman M, McDonald GM. 1997. Chemistry, biochemistry, and dietary role of potato polyphenols. A review. J Agric Food Chem 45:1523–1540
- Friedman M, Fitch TE, Yokoyama WE. 2000a. Lowering of plasma LDL cholesterol in hamsters by the tomato glycoalkaloid tomatine. Food Chem Toxicol 38:549–553
- Friedman M, Fitch TE, Levin CE, Yokoyama WH. 2000b. Feeding tomatoes to hamsters reduces their plasma low-density lipoprotein cholesterol and triglycerides. J Food Sci 65:897–900
- Friedman M. 2002. Tomato glycoalkaloids: role in the plant and in the diet. J Agric Food Chem 50:5751–5780
- Friedman M. 2004. Analysis of biologically active compounds in potatoes (Solanum tuberosum), tomatoes (Lycopersicun esculentum), and jimson weed (Datura stramonium) seeds. J Chromatogr A 1054:143–145
- Friedman M. 2013. Anticarcinogenic, cardioprotective, and other health benefits of tomato compounds lycopene, α-tomatine, and tomatidine in pure form and in fresh and processed tomatoes. J Agric Food Chem 61:9534–9550
- Fujiwara Y, Kiyota N, Tsurushima K, Yoshitomi M, Horlad H, Ikeda T, Nohara T, et al. 2012. Tomatidine, a tomato sapogenol, ameliorates hyperlipidemia and atherosclerosis in ApoE-deficient mice by inhibiting acyl-CoA: cholesterol acyl-trans-ferase (ACAT). J Agric Food Chem 60:2472–2479
- Gaffield W, Keeler RF. 1993. Implications of C-5, C-6 unsaturation as a key structural factor in steroidal alkaloids-induced mammalian teratogenesis. Experientia 49:922–924
- Gaffield W, Keeler RF. 1996. Induction of terata in hamsters by solanidine alkaloids derived from Solanum tuberosum. Chem Res Toxicol 9:426–433
- Harvey MH, McMillan M, Morgan MRA, Chan HWS. 1985a. Solanidine is present in serum of healthy individuals and in amounts dependent on their dietary potato consumption. Hum Toxicol 4:187–194
- Harvey MH, Morris BA, McMillan M, Marks Y. 1985b. Measurements of potato alkaloids in human serum and saliva by radioimmunoassay. Hum Toxicol 4:503–512
- Harvey MH, Morris BA, McMillan M, Marks Y. 1986. Potato steroidal alkaloids and neural tube defects: serum concentrations fail to demonstrate a causal relation. Hum Toxicol 5:249–253
- Hellenas KE, Nyman A, Slanina P, Loeoef L, Gabrielson J. 1992. Determination of potato glycoalkaloids and their aglycone in blood serum by high-performance liquid chromatography. Application to pharmacokinetic studies in humans. J Chromatogr 573:69–78
- Hogenboom AC, van Leerdam JA, de Voogt P. 2009. Accurate mass screening and identification of emerging contaminants in environmental samples by liquid chromatography–hybrid linear ion trap Orbitrap mass spectrometry. J Chromatogr A 1216:510–519
- Lawson DR, Erb WA, Miller AR. 1992. Analysis of Solanum alkaloids using internal standardization and capillary gas chromatography. J Agric Food Chem 40:2186–2191
- Laurila J, Laakso I, Vaananen T, Kuronen P, Huopalahti R, Pehu E. 1999. Determination of solanidine- and tmatidine-type glycoalkaloid aglycons by gas chromatography/mass spectrometry. J Agric Food Chem 47:2738–2742
- Matthew JA, Morgan MRA, McNerney R, Chan HSW, Coxon DT. 1983. Determination of solanidine in human plasma by radioimmunoassay. Food Chem Toxicol 21:637–640
- Moco S, Bino RJ, Vorst O, Verhoeven HA, De Groot J, Van Beek TA, Vervoort J, Ric de Vos CH. 2006. A liquid chromatography-mass spectrometry-based metabolome database for tomato. Plant Physiol 141:1205–1218
- Nigg HN, Ramos LE, Graham EM, Sterling J, Brown S, Cornell JA. 1996. Inhibition of human plasma and serum butyrylcholinesteras (EC 3.1.1.8) by α-chaconine and α-solanine. Fundam Appl Toxicol 33:272–281
- Tahboub YR, Zaater F, Al-Talla ZA. 2005. Determination of the limits of identification and quantitation of selected organochlorine and organophosphorous pesticide residues in surface water by full-scan gas chromatography/mass spectrometry. J Chromatogr A 1098:150–155
- Zitnak A. 1961. The occurrence and distribution of free alkaloid solanidine in Netted Gem potatoes. Can J Biochem Physiol 39:1257–1265