3
Views
5
CrossRef citations to date
0
Altmetric
Original Article

Inhibition of Stimulated Cell Responses by Phorbol Esters and Other Activators of Protein Kinase C: Sites of Action

&
Pages 143-152 | Published online: 09 Jul 2009

References

  • Abdel-Latif A. A. Calcium-mobilizing receptors, polyphosphoinosides, and the generation of second messengers. Pharmacol. Rev. 1986; 38: 227–272
  • Bennet C. F., Crooke S. T. Purification and characterization of a phos-phoinositide-specific phospholipase C from guinea pig uterus: Phosphorylation by protein kinase C in vivo. J. Biol. Chem. 1987; 262(13)789–13; 797
  • Berridge M. J. Inositol trisphosphate and diacylglycerol: Two interacting second messengers. Annu. Rev. Biochem. 1987; 56: 159–194
  • Casey P. J., Oilman A. F. G protein involvement in receptor-effector coupling. J. Biol. Chem. 1988; 263: 2577–2580
  • Cockcroft S, Barrowman M. M., Gomperts B. D. Breakdown and synthesis of polyphosphoinositides in fMet-Leu-Phe stimulated neutrophils. FEBS Lett. 1985; 181: 259–263
  • Connolly T. M., Lawing W. J., Jr., Majerus P. W. Protein kinase C phosphorylates human platelet inositol trisphosphate 5′-phosphomonoesterase, increasing the phosphatase activity. Cell 1986; 46: 951–958
  • Connolly T. M., Bansal V. S., Bross T. E., Irvine R. F., Majerus P. W. The metabolism of tris-and tetraphosphates of inositol by 5-phosphomonoesterase and 3-kinase enzymes. J. Biol. Chem. 1987; 262: 2146–2149
  • Dechaffoy de Courcelles D., Roevens P., Van Belle H. 12-O-Tetrade-canoylphorbol 13-acetate stimulates inotitol lipid phosphorylation in intact human platelets. FEBS Lett. 1984; 173: 389–393
  • Didsbury J. R., Snyderman R. Molecular cloning of a novel human GTP-binding protein and its potential role in chemoattractant stimulus-response coupling. Clin. Res. 1987; 35: 656A
  • Gierschick P, Jakobs K. H. Receptor-mediated ADP ribosylation of a phospholipase C-stimulating G protein. FEBS Lett. 1987; 224: 219–223
  • Gierschik P, Falloon J., Milligan G., Pines M., Gallin J. I., Spiegel A. Immunochemical evidence for a novel pertussis toxin substrate in human neutrophils. J. Biol. Chem. 1986; 261: 8058–8062
  • Haslam R. J. Thrombosis and Haemostasis: Signal Transduction in Platelet Activation, M. Verstraeta, J. Vermylen, H. R. Lijnen, J. Arnout, 1987; 147–174
  • Imaoka T, Asaji T. Function of platelet 47k phosphoprotein. Thromb. Haemostas 1987; 58: 496
  • Ishitoya J, Suzuki R., Takenawa T. Regulatory mechanism of inositol phospholipids metaolism. Platelet Activation, H. Yamazaki, J. F. Mustard. Academic. 1987; 43–54
  • Katada T, Oilman A. G., Watanabe Y., Bauer S., Jakobs K. H. Protein kinase C phosphorylates the inhibitory guanine nucleotide-binding regulatory component and apparently supresses its function in hormonal inhibition of adenylate cyclase. Eur. J. Biochem. 1985; 151: 431–437
  • Kato H, Ishitoya J., Takenawa T. Inhibition of inositol phospholipids metabolism and calcium mobilization by cyclic AMP-increasing agents and phorbol ester in neutrophils. Biochem. Biophys. Res. Commun. 1986; 139: 1272–1278
  • Kikuchi A, Kozawa O., Hamamori Y., Kaibuchi K., Takai Y. Inhibition of chemotactic peptide-induced phosphoinositide hydrolysis by phorbol esters through the activation of protein kinase C in differentiated human leukemia (HL-60) cells. Cancer Res. 1986; 46: 3401–3406
  • Kojima I, Shibata H., Ogata E. Phorbol ester inhibits angiotensin-induced activation of phospholipase C in adrenal glomerulosa cells. Its implication in the sustained action of angiotensin. Biochem. J. 1986; 237: 253–258
  • Labarca R, Janowsky A., Patel J., Paul S. M. Phorbol esters inhibit agonist induced [3H]inositol-l-phosphate accumulation in rat hippocampal slices. Biochem. Biophys. Res. Commun. 1984; 123: 703–709
  • Matsumoto T, Molski T. F.P., Volpi M., Pelz C., Kanaho Y., Becker E. L., Feinstein M. B., Naccache P. H., Sha'afi R. I. Treatment of rabbit neutrophils with phorbol esters results in increased ADP-ribosylation catalyzed by pertussis toxin and inhibition of the GTP-ase stimulated by fMet-Leu-Phe. FEBS Lett. 1986; 198: 295–300
  • Matsumoto T, Molski T. F.P., Kanaho Y., Becker E. L., Sha'afi R. I. G-protein dissociation, GTP-GDP exchange and GTP-ase activity in control and PMA treated neutrophils stimulated by fMet-Leu-Phe. Biochem. Biophys. Res. Commun. 1987; 143: 489–498
  • MacIntyre D. E., McNicol A., Drummond A. H. Tumour-promoting phorbol esters inhibit agonist-induced phosphatidate formation and Ca2+ flux in human platelets. FEES Lett. 1985; 180: 160–164
  • Molina Y, Vedia L. M., Lapetina E. G. Phorbol 12,13-dibutyrate and 1-oleyl-2-acetyldiacylglycerol stimulate inositol trisphosphate dephosphorylation in human platelets. J. Biol. Chem. 1986; 261: 10, 493–10; 495
  • Molski T. F.P., Tao W., Becker E. L., Sha'afi R. I. Intracellular calcium rise produced by platelet-activating factor is deactivated by fMet-Leu-Phe and this requires uninterrupted activation sequence: Role of protein kinase C. Biochem. Biophys. Res. Commun. 1988; 151: 836–843
  • Naccache P. H., Molski T. F.P., Borgeat P., White J. R., Sha'afi R. I. Phorbol esters inhibit the fMet-Leu-Phe and Leukotriene B4-stimulated calcium mobilization and enzyme secretion in rabbit neutrophils. J. Biol. Chem. 1985; 260: 2125–2131
  • Nishizuka Y. Studies and perspective of protein kinase C. Science (USA) 1986; 233: 305–312
  • Okano Y, Takagi H., Nakashima S., Tohmatsu T., Nozawa Y. Inhibitory action of phorbol myristate acetate on histamine secretion and polyphospho-inositide turnover induced by compound 48/80 in mast cells. Biochem. Biophys. Res. Commun. 1985; 132: 110–117
  • Omann G. M., Allen R. A., Bokoch G. M., Painter R. G., Traynor A. E., Sklar L. A. Signal transduction and cytoskeletal activation in the neutrophil. Physiol. Rev. 1987; 67: 285–322
  • Orellana S. A., Solski P. A., Brown J. H. Phorbol ester inhibits phosphoinositide hydrolysis and calcium mobilization in cultured astrocytoma cells. J. Biol. Chem. 1985; 260: 5236–5239
  • Orellana S. A., Solski P. A., Brown J. H. Guanosine 5′-O-(thiotriphosphate)-dependent inositol trisphosphate formation in membranes is inhibited by phorbol ester and protein kinase C. J. Biol. Chem. 1987; 262: 1638–1643
  • Owen C. S. Phorbol ester (12-O-tetradecanoylphorbol 13-acetate) partially inhibits rapid intracellular free calcium transients triggered by anti-immunoglobulin in murine lymphocytes. J. Biol. Chem. 1988; 263: 2732–2737
  • Pfeilschifter J. Tumour promotor 12-O-tetradecanoylphorbol 13-acetate inhibits angiotension II-induced inositol phosphate production and cytosolic Ca2+ rise in rat renal mesangial cells. FEBS Lett. 1986; 203: 262–266
  • Pfeilschifter J, Bauer C. Different effects of phorbol ester on angiotensin II-and stable GTP analogue-induced activation of polyphosphoinoside phosphodies-terase in membranes isolated from rat renal mesangial cells. Biochem. J. 1987; 248: 209–215
  • Poll C, Westwick J. Phorbol esters modulate thrombin-operated calcium mobilization and dense granule release in human platelets. Biochim. Biophys. Acta 1986; 886: 434–440
  • Poll C, Kyrle P., Westwick J. Activation of protein kinase C inhibits sodium fluoride-induced elevation of human platelet cytosolic free calcium and thromboxane B2 generation. Biochem. Biophys. Res. Commun. 1986; 136: 381–389
  • Richard J. E., Sheterline P. Evidence that phorbol ester interferes with stimulated Ca2+ redistribution by activating Ca2+ -efflux in neutrophil leucocytes. Biochem. J. 1985; 231: 623–628
  • Rittenhouse S. E., Sasson J. P. Mass changes in myoinositol trisphosphate in human platelets stimulated by thrombin. Inhibitory effects of phorbol ester. J. Biol. Chem. 1985; 260: 8657–8660
  • Rossi F. The O2−-forming NADPH oxidase of the phagocytes: Nature, mechanisms of activation and function. Biochim. Biophys. Acta 1986; 853: 65–89
  • Sha'afi R. I., Molski T. F.P., Huang C. K., Naccache P. H. The inhibition of neutrophil responsiveness caused by phorbol esters is blocked by the protein kinase C inhibitor H-7. Biochem. Biophys. Res. Commun. 1986; 137: 50–60
  • Sha'afi R. I., Molski T. F.P. Activation of the neutrophil. Prog. Allergy 1988; 42: 1–64
  • Smith C. D., Uhing R. J., Snyderman R. Nucleotide regulatory protein-mediated activation of phospholipase C in human polymorphonuclear leukocytes is disrupted by phorbol esters. J. Biol. Chem. 1987; 262: 6121–6127
  • Snyderman R, Smith C. D., Verghese M. W. Model for leukocyte regulation by chemoattractant receptors: Roles of a guanine nucleotide regulatory protein and polyphosphoinositide metabolism. J. Leuk. Biol. 1986; 40: 785–800
  • Stryer L, Bourne H. R. G proteins: A family of signal transducers. Annu. Rev. Cell Biol. 1986; 2: 391–419
  • Tauber A. I. Protein kinase C and the activation of the human neutrophil NADPH-oxidase. Blood 1987; 69: 711–720
  • Tohmatsu T, Harroti H., Nagao S., Ohki K., Nozowa Y. Reversal of protein kinase C inhibitor of suppressive actions of phorbol 12-myristate-13-acetate on polyphosphoinositide metabolism and cytosolic Ca2+ mobilization in thrombin-stimulated human platelets. Biochem. Biophys. Res. Commun. 1986; 134: 868–875
  • Uratsuji Y, Nakanishi H., Takeyama Y., Kishimoto A., Nishizuka Y. Activation of cellular protein kinase C and mode of inhibitory action of phospholipid-interacting compounds. Biochem. Biophys. Res. Commun. 1985; 130: 654–661
  • Vegesna R. V.K., Wu H. L, Mong S., Crooke S. T. Staurosporine inhibits protein kinase C and prevents phorbol ester-mediated leukotriene D4 receptor desensitization in RBL-1 cells. Mol. Pharmacol. 1988; 33: 537–542
  • Williamson J. R., Hansen C. A., Verhoeven A., Coll K. E., Johanson R., Williamson M. T., Filburn C. Cell Calcium and the Control of Membrane Transport, D. C. Eaton, L. J. Mandel. Rockefeller University Press, New York 1987; 93–116
  • Zavoico G. B., Halenda S. P., Sha'afi R. L., Feinstein M. B. Phorbol myristate acetate inhibits thrombin-stimulated Ca2+ mobilization and phosphatidyli-nositol 4,5-bisphosphate hydrolysis in human platelets. Proc. Nat. Acad. Sci. USA 1985; 82: 3859–3862
  • Zik Y, Sagi-Eisenberg R., Pines M., Gierschif P., Spiegel A. M. Multisite phosphorylation of the a subunit of transducin by the insulin receptor kinase and protein kinase C. Proc. Natl. Acad. Sci. USA 1986; 83: 9294–9297

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.