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Original Article

A Comparative Study of the Performance of Solid Supported and Soluble α-Chymotrypsin for the Enzymatic Synthesis of Kyotorphin

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Pages 19-28 | Published online: 11 Jul 2009

References

  • Box G. E. P., Wilson K. B. On the experimental attainment of optimal conditions. J. Roy. Statist. Soc., Series B 1951; 13: 7–45
  • Clapés P., Valencia G., Reig F., García-Antón J. M., Mata J. Kinetically controlled synthesis of kyotorphin. An optimization study. Appl. Biochem. Biotech 1988a, (in press)
  • Gapés P., Valencia G., Torres J. L., Reig F., García-Antón J. M., Mata J. Kinetic study of α-chymotrypsin-catalyzed synthesis of kyotorphin. Biochim. Biophys. Acta 1988b, (in press)
  • Davies O. L. Design and analysis of industrial experiments. Oliver & Boy, London 1963
  • Engasser J. R., Horvath C. Electrostatic effects on the kinetics of bound enzymes. Biochem. J. 1975; 145: 431–435
  • Goldstein L. Kinetic behaviour of immobilized enzyme systems. Methods in enzymology-Immobilized enzymes, K. Mosbach. Academic Press, New York 1976; vol. 44: 397–443
  • Koennecke A., Schellenberger V., Hofmann H. J., Jakubke H. D. Die partitionskonstante als effiziensparameter von nucleophilen bei enzymkatalilysierten kinetish kontrollierten peptidsynthesen. Pharmazie 1984; 39: 785–786
  • Levenspiel O. Chemical Reaction Engineering. John Wiley, New York 1972; 163–209
  • Manecke G., Ehrentahl E., Schlunsen J. Determination of active protein. Characterization of Immobilized Biocatalysts, K. Buchholz. Verlag Chemie Frankfurt am Main. 1979; 193–198
  • Monsan P. Optimization of glutaraldehyde activation of a support for enzyme immobilization. J. Mol. Catal. 1977/1978; 3: 371–384
  • Peterson G. L. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal. Biochem. 1977; 8: 346–356
  • Schellenberger V., Jakubke H. D. A spectrophotometric assay of the S' subsite specifically of α-chymotrypsin. Biochim. Biophys. Acta 1986; 869: 54–60
  • Schellenberger V., Jakubke H. D. Studies on system properties influencing the partitioning constant in kinetically controlled enzymatic peptide synthesis. Peptides 1986, D. Theodoropoulos. Walter de Gruyter, Berlin 1987; 195–199
  • Takagi H., Shioni H., Ueda H, Amano H. A novel dipeptide from bovine brain is a possible Met-enkephalin releaser. Nature 1979; 82: 410–412
  • Wunsch E. Methoden der Organischen Chemie 15/1. Synthese von Peptiden, E. Muller. Georg Thieme Verlag, Stuttgart 1974; 1: 47–69; 453–460

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