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Stress
The International Journal on the Biology of Stress
Volume 19, 2016 - Issue 2
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Original Research Report

Documenting stress in caregivers of transplantation patients: initial evidence of HPA dysregulation

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Pages 175-184 | Received 17 Sep 2015, Accepted 10 Jan 2016, Published online: 07 Mar 2016

References

  • ACS. American Cancer Society. Cancer Facts & Figures 2015 [Online]. American Cancer Society, available at http://www.cancer.org/research/cancerfactsstatistics/cancerfactsfigures2015/index (accessed 21 August 2015)
  • Ahrens T, Deuschle M, Krumm B, van der Pompe G, den Boer JA, Lederbogen F. (2008). Pituitary-adrenal and sympathetic nervous system responses to stress in women remitted from recurrent major depression. Psychosom Med 70:461–7
  • Andersson I, Ahlberg K, Stockelberg D, Brune M, Persson LO. (2009). Health-related quality of life in patients undergoing allogeneic stem cell transplantation after reduced intensity conditioning versus myeloablative conditioning. Cancer Nurs 32:325–34
  • Beattie S, Lebel S. (2011). The experience of caregivers of hematological cancer patients undergoing a hematopoietic stem cell transplant: a comprehensive literature review. Psychooncology 20:1137–50
  • Bishop MM, Curbow BA, Springer SH, Lee JA, Wingard JR. (2011). Comparison of lasting life changes after cancer and BMT: perspectives of long-term survivors and spouses. Psychooncology 20:926–34
  • Burke HM, Davis MC, Otte C, Mohr DC. (2005). Depression and cortisol responses to psychological stress: A meta-analysis. Psychoneuroendocrinology 30:846–56
  • Burton LC, Newsom JT, Schulz R, Hirsch CH, German PS. (1997). Preventive health behaviors among spousal caregivers. Prev Med 26:162–9
  • Chrousos GP. (2009). Stress and disorders of the stress system. Nat Rev Endocrinol 5:374–81
  • Chrousos GP, Gold PW. (1992). The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis. JAMA 267:1244–52
  • Cohen S. (1988). Perceived stress in a probability sample of the United States. In: Spacapan S, Oskamp S editors. The social psychology of health. Thousand Oaks, CA: Sage Publications, Inc. p 31–67
  • Cohen S, Kamarck T, Mermelstein R. (1983). A global measure of perceived stress. J Health Soc Behav 24:385–96
  • Dallman MF. (2010). Stress-induced obesity and the emotional nervous system. Trends Endocrinol Metab 21:159–65
  • Eisenhofer G, Goldstein DS, Stull R, Keiser HR, Sunderland T, Murphy DL, Kopin IJ. (1986). Simultaneous liquid-chromatographic determination of 3,4-dihydroxyphenylglycol, catecholamines, and 3,4-dihydroxyphenylalanine in plasma, and their responses to inhibition of monoamine oxidase. Clin Chem 32:2030–3
  • Eisenhofer G, Kopin IJ, Goldstein DS. (2004). Catecholamine metabolism: a contemporary view with implications for physiology and medicine. Pharmacol Rev 56:331–49
  • Foster LW, McLellan LJ, Rybicki LA, Sassano DA, Hsu A, Bolwell BJ. (2004). Survival of patients who have undergone allogeneic bone marrow transplantation: the relative importance of in-hospital lay care-partner support. J Psychosoc Oncol 22:1–20
  • Frey P, Stinson T, Siston A, Knight SJ, Ferdman E, Traynor A, O'Gara K, et al. (2002). Lack of caregivers limits use of outpatient hematopoietic stem cell transplant program. Bone Marrow Transplant 30:741–8
  • Girdler SS, Pedersen CA, Straneva PA, Leserman J, Stanwyck CL, Benjamin S, Light KC. (1998). Dysregulation of cardiovascular and neuroendocrine responses to stress in premenstrual dysphoric disorder. Psychiatry Res 81:163–78
  • Girgis A, Lambert S, Johnson C, Waller A, Currow D. (2013). Physical, psychosocial, relationship, and economic burden of caring for people with cancer: a review. J Oncol Pract 9:197–202
  • Given CW, Given B, Stommel M, Collins C, King S, Franklin S. (1992). The caregiver reaction assessment (CRA) for caregivers to persons with chronic physical and mental impairments. Res Nurs Health 15:271–83
  • Grissom N, Bhatnagar S. (2009). Habituation to repeated stress: get used to it. Neurobiol Learn Mem 92:215–24
  • Grov EK, Fossa SD, Tønnessen A, Dahl AA. (2006). The caregiver reaction assessment: psychometrics, and temporal stability in primary caregivers of Norwegian cancer patients in late palliative phase 29. Psycho-Oncol 15:517–27
  • Hurley RV, Patterson TG, Cooley SJ. (2014). Meditation-based interventions for family caregivers of people with dementia: a review of the empirical literature. Aging Ment Health 18:281–8
  • Juster RP, McEwen BS, Lupien SJ. (2010). Allostatic load biomarkers of chronic stress and impact on health and cognition. Neurosci Biobehav Rev 35:2–16
  • Kassel JD, Stroud LR, Paronis CA. (2003). Smoking, stress, and negative affect: correlation, causation, and context across stages of smoking. Psychol Bull 129:270–304
  • Klatzkin RR, Lindgren ME, Forneris CA, Girdler SS. (2010). Histories of major depression and premenstrual dysphoric disorder: evidence for phenotypic differences. Biol Psychol 84:235–47
  • Koolhaas JM, Bartolomucci A, Buwalda B, de Boer SF, Flugge G, Korte SM, Meerlo P, et al. (2011). Stress revisited: a critical evaluation of the stress concept. Neurosci Biobehav Rev 35:1291–301
  • Kroenke K, Yu ZS, Wu JW, Kean J, Monahan PO. (2014). Operating characteristics of PROMIS four-item depression and anxiety scales in primary care patients with chronic pain. Pain Med 15:1892–901
  • Laudenslager ML. (2014). “Anatomy of an Illness”: control from a caregiver's perspective. Brain Behav Immun 36:1–8
  • Laudenslager ML, Simoneau TL, Kilbourn K, Natvig C, Philips S, Spradley J, Benitez P, et al. (2015). A randomized control trial of a psychosocial intervention for caregivers of allogeneic hematopoietic stem cell transplant patients: effects on distress. Bone Marrow Transplant 50:1110–18
  • Lavretsky H, Epel ES, Siddarth P, Nazarian N, Cyr NS, Khalsa DS, Lin J, et al. (2013). A pilot study of yogic meditation for family dementia caregivers with depressive symptoms: effects on mental health, cognition, and telomerase activity. Int J Geriatr Psychiatry 28:57–65
  • Lenders JW, Eisenhofer G, Armando I, Keiser HR, Goldstein DS, Kopin IJ. (1993). Determination of metanephrines in plasma by liquid chromatography with electrochemical detection. Clin Chem 39:97–103
  • Li J, Cowden LG, King JD, Briles DA, Schroeder HW, Jr Stevens AB, Perry RT, et al. (2007). Effects of chronic stress and interleukin-10 gene polymorphisms on antibody response to tetanus vaccine in family caregivers of patients with Alzheimer's disease. Psychosom Med 69:551–9
  • Lovell B, Wetherell MA. (2011). The cost of caregiving: endocrine and immune implications in elderly and non elderly caregivers. Neurosci Biobehav Rev 35:1342–52
  • Lucini D, Cannone V, Malacarne M, Bruno D, Beltrami S, Pizzinelli P, Piazza E, et al. (2008). Evidence of autonomic dysregulation in otherwise healthy cancer caregivers: a possible link with health hazard. Eur J Cancer 44:2437–43
  • McEwen BS. (2000). Allostasis and allostatic load: implications for neuropsychopharmacology. Neuropsychopharmacology 22:108–24
  • McEwen BS, Seeman T. (1999). Protective and damaging effects of mediators of stress. Elaborating and testing the concepts of allostasis and allostatic load. Ann NY Acad Sci 896:30–47
  • McReynolds JR, Pena DF, Blacktop JM, Mantsch JR. (2014). Neurobiological mechanisms underlying relapse to cocaine use: contributions of CRF and noradrenergic systems and regulation by glucocorticoids. Stress 17:22–38
  • Meewisse ML, Reitsma JB, De Vries GJ, Gersons BPR, Olff M. (2007). Cortisol and post-traumatic stress disorder in adults: systematic review and meta-analysis. Br J Psychiatry 191:387–92
  • Milbury K, Badr H, Fossella F, Pisters KM, Carmack CL. (2013). Longitudinal associations between caregiver burden and patient and spouse distress in couples coping with lung cancer. Support Care Cancer 21:2371–9
  • NAC. National Alliance for Caregiving. (2009). Caregiving in the U.S. [Online]. National Alliance for Caregiving and American Association of Retired Persons, available at http://www.caregiving.org/data/Caregiving_in_the_US_2009_full_report.pdf (accessed 20 August 2010)
  • Northouse LL, Katapodi MC, Song L, Zhang L, Mood DW. (2010). Interventions with family caregivers of cancer patients: meta-analysis of randomized trials. CA Cancer J Clin 60:317–39
  • Pacak K, Kvetnansky R, Palkovits M, Fukuhara K, Yadid G, Kopin IJ, Goldstein DS. (1993). Adrenalectomy augments in vivo release of norepinephrine in the paraventricular nucleus during immobilization stress. Endocrinology 133:1404–10
  • Pervanidou P, Kolaitis G, Charitaki S, Lazaropoulou C, Papassotiriou I, Hindmarsh P, Bakoula C, et al. (2007). The natural history of neuroendocrine changes in pediatric posttraumatic stress disorder (PTSD) after motor vehicle accidents: progressive divergence of noradrenaline and cortisol concentrations over time. Biol Psychiatry 62:1095–102
  • Petruzzi A, Finocchiaro CY, Lamperti E, Salmaggi A. (2013). Living with a brain tumor : reaction profiles in patients and their caregivers. Support Care Cancer 21:1105–11
  • PROMIS. (2011). Patient Reported Outcomes Measurement Information System (PROMIS) [Online]. NIH, available at http://www.nihpromis.org/ (accessed 20 May 2011)
  • Pruessner JC, Hellhammer DH, Kirschbaum C. (1999). Burnout, perceived stress, and cortisol responses to awakening. Psychosom Med 61:197–204
  • Rabasa C, Gagliano H, Pastor-Ciurana J, Fuentes S, Belda X, Nadal R, Armario A. (2015). Adaptation of the hypothalamus-pituitary-adrenal axis to daily repeated stress does not follow the rules of habituation: a new perspective. Neurosci Biobehav Rev 56:35–49
  • Rohleder N, Marin TJ, Ma R, Miller GE. (2009). Biologic cost of caring for a cancer patient: dysregulation of pro- and anti-inflammatory signaling pathways. J Clin Oncol 27:2909–15
  • Rose M, Bjomer JB, Becker J, Fries JF, Ware JE. (2008). Evaluation of a preliminary physical function item bank supported the expected advantages of the patient-reported outcomes measurement information system (PROMIS). J Clin Epidemiol 61:17–33
  • Rosmond R, Dallman MF, Bjorntorp P. (1998). Stress-related cortisol secretion in men: relationships with abdominal obesity and endocrine, metabolic and hemodynamic abnormalities. J Clin Endocrinol Metab 83:1853–9
  • Shah NS, Donald AG. (1984). Psychoneuroendocrine dysfunction. New York, NY: Springer US/Plenum Publishing Corporation
  • Simoneau TL, Mikulich-Gilbertson SK, Natvig C, Kilbourn K, Spradley J, Grzywa-Cobb R, Philips S, et al. (2013). Elevated peri-transplant distress in caregivers of allogeneic blood or marrow transplant patients. Psycho-Oncol 22:2064–70
  • Sterling P. (2004). Principals of allostasis: optimal design, predictive regulation, pathophysiology, and rational therapeutics. Cambridge, UK: Cambridge University Press
  • Utne I, Miaskowski C, Paul SM, Rustoen T. (2013). Association between hope and burden reported by family caregivers of patients with advanced cancer. Support Care Cancer 21:2527–35
  • Van Reeth O, Weibel L, Spiegel K, Leproult R, Dugovic C, Maccari S. (2000). Interactions between stress and sleep: from basic research to clinical situations. Sleep Med Rev 4:201–19
  • Vitaliano PP, Zhang J, Scanlan JM. (2003). Is caregiving hazardous to one's physical health? A meta-analysis. Psychol Bull 129:946–72
  • Wu SM, Yang HC, Thayer JF, Andersen BL. (2014). Association of the physiological stress response with depressive symptoms in patients with breast cancer. Psychosom Med 76:252–6

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