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Stress
The International Journal on the Biology of Stress
Volume 4, 2001 - Issue 3
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Original Article

Maternal Stress in Pregnancy and its Effect on the Human Foetus: An Overview of Research Findings

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Pages 195-203 | Received 20 Oct 2000, Published online: 07 Jul 2009

References

  • Austin M -P., Leader L. “Maternal stress and obstetric and infant outcomes: epidemiological findings and neuroendo-crine mechanisms”,. Ann. N. Z. J. Obstet. Gynaecol 2000; 40: 331–337
  • Barbazanges A., Piazza P., Le Moal M., Maccari S. “Maternal glucocorticoid secretion mediates long-term effects of prenatal stress”,. J. Neurosci 1996; 16: 3943–3949
  • Barker D. J. 'The fetal origins of adult disease”,. Proc. R. Soc. Land. B Biol. Sci 1995; 262: 37–43
  • Barker D J. “The fetal origins of type 2 diabetes mellitus”,. Ann. Int. Med 1999; 130: 322–324
  • Barker D J., Hales C N., Fall C H., Osmond C, Phipps K., Clark P M. “Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth”,. Diabetologia 1993; 36: 62–67
  • Benediktsson R., Lindsay R S., Noble J., Seckl J R., Edwards C R. “Glucocorticoid exposure in utero: new model for adult hypertension”,. Lancet 1993; 341: 339–341
  • Benediktsson R., Calder A A., Edwards C R., Seckl J R. “Placental 11 beta-hydroxysteroid dehydrogenase: a key regulator of fetal glucocorticoid exposure”,. Clin. Endocrinol 1997; 46: 161–166
  • Boksa P., Krishnamurthy A., Sharma S. “Hippocampal and hypothalamic type 1 corticosteroid receptor affinities are reduced in adult rats born by a caesarean section procedure with or without an added period of anoxia”,. Neuroendocrinology 1996; 64: 25–34
  • Clarke A S., Schneider M L. “Prenatal stress has long-term effects on behavioural responses to stress in juvenile rhesus monkeys”,. Dev. Psychobiol 1993; 26: 293–304
  • Clarke A S., Schneider M L. “Effects of prenatal stress on behaviour in adolescent rhesus monkeys”,. Ann. N. Y. Acad. Sci 1997; 807: 490–491
  • Clarke A S., Wittwer D J., Abbott D H., Schneider M L. “Long-term effects of prenatal stress on HPA axis activity in juvenile rhesus monkeys”,. Dev. Psychobiol 1994; 27: 257–269
  • Copper R L., Goldenber R L., Das A., Elder N., Swain M., Norman G. “The preterm prediction study: maternal stress is associated with spontaneous preterm birth at less than thirty five weeks gestation”,. Am. J. Obstet. Gynecol 1996; 175: 1286–1292
  • Donaldson A., Nicolini U., Symes E K., Rodeck C H., Tannirandorn Y. “Changes in concentrations of cortisol, dehydroepiandrosterone sulphate and progesterone in fetal and maternal serum during pregnancy”,. Clin. Endocrinol 1991; 35: 447–451
  • Epstein M F., Farrell P M., Sparks J W., Pepe G., Driscoll S G., Chez R A. “Maternal betamethasone and fetal growth and development in the monkey”,. Am. J. Obstet. Gynecol 1977; 127: 261–263
  • Feldman P J., Dunkel-Schetter C, Sandman C A., Wadwa P D. “Maternal social support predicts birth weight and fetal growth in human pregnancy”,. Psychosom. Med 2000; 62: 715–725
  • Field T., Sandberg D., Quetel T A., Garcia R., Rosario M. “Effects of ultrasound feedback on pregnancy anxiety, fetal activity, and neonatal outcome”,. Obstet. Gynecol 1985; 66: 525–528
  • Giannakoulopoulos X., Sepulveda W., Kourtis P., Glover V., Fisk N M. “Fetal plasma cortisol and beta-endorphin response to intrauterine needling”,. Lancet 1994; 344: 77–81
  • Giannakoulopoulos X., Teixeira J., Fisk N., Glover V. “Human fetal and maternal noradrenaline responses to invasive procedures”,. Pediatr. Res 1999; 45: 494–499
  • Gitau R., Cameron A., Fisk N M., Glover V. “Fetal exposure to maternal cortisol”,. Lancet 1998; 352: 707–708
  • Gitau R., Fisk N., Teixeira J., Cameron A., Glover V. “Fetal HPA stress responses to invasive procedures are independent of maternal responses”,. J. Clin. Endocrinol. Metab 2001a; 86: 104–109
  • Gitau R., Menson E., Pickles V., Fisk N M., Glover V., MacLachlan N. “Cord cortisol levels as an indicator of the fetal stress response to assisted vaginal delivery”. Eur. J. Obstet. Gynaecol. Reprod. Biol 2001b
  • Goland R S., Jozak S., Warren W B., Conwell I M., Stark R I., Tropper P J. “Elevated levels of umbilical cord plasma corticotropin-releasing hormone in growth-retarded fetuses”,. J. Clin Endocrinol. Metab 1993; 77: 1174–1179
  • Hansen D., Lou H C., Olsen J. “Serious life events and congential malformations: a national study with complete follow-up”,. Lancet 2000; 356: 875–880
  • Hedegaard M., Henriksen T B., Sabroe S., Secher N J. “Psychological distress in pregnancy and preterm delivery”,. BMJ 1993; 307: 235–239
  • Henry C, Kabbaj M., Simon H., Le Moal M., Maccari S. “Prenatal stress increases the hypothalamo-pituitary-adrenal axis response in young and adult rats”,. J. Neuroendocrinol 1994; 6: 341–345
  • Hultman C M., Sparen P., Takei N., Murray R M., Cnattingius S., Geddes J. “Prenatal and perinatal risk factors for schizophrenia, affective psychosis, and reactive psychosis of early onset: case-control”,. BMJ 1999; 318: 421–426
  • Insel T. “Prenatal stress has long term effects on brain opiate receptors”,. Brain Res 1990; 511: 93–97
  • Jacobsen G., Schei B., Hoffman H J. “Psychosocial factors and small-for-gestational-age infants among parous Scandinavian women”,. Acta Obstet. Gynecol. Scand. Suppl 1997; 165: 14–18
  • Kanayama N., Tsujimura R., She L., Maehara K., Terao T. “Cold-induced stress stimulates the sympathetic nervous system, causing hypertension and proteinuria in rats”,. J. Hypertens 1997; 15: 383–389
  • Khong T Y., De Wolf F., Robertson W B., Brosens I. “Inadequate maternal vascular response to placentation in pregnancies complicated by pre-eclampsia and by small-for-gestational age infants”,. Br. J. Obstet. Gynaecol 1986; 93: 1049–1059
  • Lobel M., Dunkel-Schetter C., Scrimshaw S C. “Prenatal maternal stress and prematurity: a prospective study of socioeconomically disadvantaged women”,. Health Psychol 1992; 11: 32–40
  • Lopez-Bernal A., Flint A P.F., Anderson A B.M., Turnbull A C. “llb-hydroxysteriod dehydrogenase activity in human placenta and decidua”,. J. Steroid Biochem 1980; 13: 1081–1087
  • Lou H., Hansen D., Nordentoft M., Pyrds O., Jensenn K, Nim J., Hemminsen R. “Prenatal stressors of human life affect fetal brain development”,. Dev. Med. Child Neurol 1994; 36: 826–832
  • Meaney M., Bhatnager S., Diorio J. “Molecular basis for the development of individual differences in the hypothala-mic-pituitary-adrenal stress response”,. Cell. Mol. Neurobiol 1993; 13: 321–347
  • Meijer A. “Child psychiatric sequelae of maternal war stress”,. Acta Psychiar. Scand 1985; 72: 505–511
  • Mosier H D.J., Dearden L C., Jansons R A., Roberts R C., Biggs C S. “Disproportionate growth of organs and body weight following glucocorticoid treatment of the rat fetus”,. Dev. Pharmacol. Ther 1982; 4: 89–105
  • Murphy B E.P., Clark S J., Donald I R., Pinsky M., Vedady D. “Conversion of maternal cortisol to cortisone during placental transfer to the human fetus”,. Am. J. Obstet. Gynecol 1974; 118: 538–541
  • Nordentoft M., Lou H C., Hansen D., Nim J., Pryds O., Rubin P., Hemmingsen R. “Intrauterine growth retardation and premature delivery: the influence of maternal smoking and psychosocial factors”,. Am. J. Public Health 1996; 86: 347–354
  • Novy M J., Walsh S W. “Dexamethasone and estradiol treatment in pregnant rhesus macaques: effects on gestational length, maternal plasma hormones, and fetal growth”,. Am. J. Obstet. Gynecol 1983; 145: 920–931
  • Perkin M R., Bland J M., Peacock J L., Anderson H R. “The effect of anxiety and depression during pregnancy on obstetric complications”,. Br. J. Obstet. Gynaecol 1993; 100: 629–634
  • Petraglia E, Potter E., Cameron V A., Sutton S., Behan D P., Woods R J., Sawchenko P E., Lowry P J., Vale W. “Corticotropin-releasing factor-binding protein is produced by human placenta and intrauterine tissues”,. J. Clin. Endocrinol. Metab 1993; 77: 919–924
  • Reinisch J M., Simon N G., Karow W G., Gandelman R. “Prenatal exposure to prednisone in humans and animals retards intrauterine growth”,. Science 1978; 202: 436–438
  • Rosenfeld C R., West J. “Circulatory response to systemic infusion of norepinephrine in the pregnant ewe”,. Am. J. Obstet. Gynecol 1977; 127: 376–383
  • Schneider M L., Suomi S J. “Neurobehavioural assessment in rhesus monkey neonates (Macaca mulatta): Developmental changes, behavioral stability, and early experience”,. Inf. Behav. Dev 1992; 15: 155–177
  • Schneider M L., Roughton E C., Koehler A J., Lubach G R. “Growth and development following prenatal stress exposure in primates: an examination of ontogenetic vulnerability”,. Child Dev 1999; 70: 263–274
  • Schulte H M., Weisner D., Allolio B. “The corticotrophin releasing hormone test in late pregnancy: lack of adrenocorticotrophin and cortisol response”,. Clin. Endocrinol 1990; 33: 99–106
  • Seckl J R. “Glucocorticoids and small babies (editorial)”. Quart. J. Med 1994; 87: 259–262
  • Spielberger CD. State-trait Anxiety Inventory for Adults. Sampler Set, Manual Test, Scoring Key. Consulting Psychologists Press Inc., Mind Garden Pao Alto, California 1983
  • Stott D H. “Follow-up study from birth of the effects of prenatal stresses”,. Dev. Med. Child Neurol 1973; 15: 770–787
  • Taylor A., Fisk N M., Glover V. “Mode of delivery and later stress response”,. Lancet 2000; 355: 120
  • Teixeira J., Fogliani R., Giannakoulopoulos X., Glover V., Fisk N M. “Fetal haemodynamic stress response to invasive procedures”,. Lancet 1996; 347: 624
  • Teixeira J M., Fisk N M., Glover V. “Association between maternal anxiety in pregnancy and increased uterine artery resistance index: cohort based study”,. BMJ 1999a; 318: 153–157
  • Teixeira J M., Glover V., Fisk N M. “Acute cerebral redistribution in response to invasive procedures in the human fetus”,. Am. J. Obstet. Gynecol 1999b; 181: 1018–1025
  • Uno H., Lohmiller L., Thieme C, Kemnitz J W., Engle M J., Roecker E B., Farrell P M. “Brain damage induced by prenatal exposure to dexamethasone in fetal rhesus macaques I. Hippocampus”,. Dev. Brain Res 1990; 53: 157–167
  • Villar J., Farnot U., Barros F., Victora C, Langer A., Belizan J M. “A randonmised trial of psychosocial support during high-risk pregnancies. The Latin American network for Perinatal and Reproductive Research”,. N. Engl. J. Med 1992; 327: 1266–1271
  • Wadhwa P D., Sandman C A., Porto M., Dunkel Schette C., Garite T J. 'The association between prenatal stress and infant birth weight and gestational age at birth: a prospective investigation”,. Am. J. Obstet. Gynecol 1993; 169: 858–865

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