Increased spontaneous activity and reduced inotropic response to catecholamines in ventricular myocytes from footshock-stressed rats

References

• Arunlakshana O, Schild HO. 1959. Some quantitative uses of drug antagonists. Br J Pharmacol Chemother. 14:48–58.
   PubMed Web of Science ®Google Scholar
• Bao X, Lu CM, Liu F, Gu Y, Dalton ND, Zhu B, Foster E, Chen J, Karliner JS, Ross JJr, . 2007. Epinephrine is required for normal cardiovascular responses to stress in the phenylethanolamine N-methyltransferase knockout mouse. Circulation. 116:1024–1031.
   PubMed Web of Science ®Google Scholar
• Bassani RA, Bassani JWM. 1993. Effects of escapable and inescapable foot-shock on rat atrial β-adrenoceptors. Pharmacol Biochem Behav. 44:869–875.
   PubMed Web of Science ®Google Scholar
• Bassani RA, De Moraes S. 1987. Subsensitivity to β-adrenoceptor agonists in right atria isolated from footshock-stressed rats. Gen Pharmacol. 18:473–477.
   PubMedGoogle Scholar
• Bassani RA, De Moraes S. 1988. Effects of repeated footshock stress on the chronotropic responsiveness of the isolated pacemaker of the rat: Role of beta-2 adrenoceptors. J Pharmacol Exp Ther. 246:316–321.
   PubMed Web of Science ®Google Scholar
• Bassani JWM, Yuan W, Bers DM. Fractional Ca release is regulated by trigger Ca and SR Ca content in cardiac myocytes. Am J Physiol Cell Physiol. 1995a; 268:C1313–C1319.
   PubMed Web of Science ®Google Scholar
• Bassani RA, Mattiazzi A, Bers DM. CaMKII is responsible for activity-dependent acceleration of relaxation in rat ventricular myocytes. Am J Physiol Heart Circ Physiol. 1995b; 268:H703–H713.
   Web of Science ®Google Scholar
• Bassani RA, Bassani JWM, Lipsius SL, Bers DM. 1997. Diastolic Ca efflux in atrial pacemaker cells and Ca-overloaded myocytes. Am J Physiol Heart Circ Physiol. 273:H886–HH892.
   Web of Science ®Google Scholar
• Boer DC, Bassani RA. 2004. Quantitation of the dose-response relationship for arrhythmogenic agents in isolated cardiac tissue. Braz J Biomed Eng. 20:3–10.
   Google Scholar
• Boer DC, Bassani JWM, Bassani RA. 2004. Catecholamine-dependent spontaneous activity is mediated by β1-adrenoceptors in rat myocardium. J Mol Cell Cardiol. 37:149 (abstr).
   Web of Science ®Google Scholar
• Brodsky MA, Sato DA, Iseri LT, Wolff LJ, Allen BJ. 1987. Ventricular tachyarrhythmia associated with psychological stress: The role of sympathetic nervous system. JAMA. 257:2064–2067.
   PubMed Web of Science ®Google Scholar
• Brotto MAP. 2003. Temporal effects of stress by immobilization and sensitivity of the isolated rat pacemaker to isoproterenol: Roles of corticosterone, neuronal uptake, and β-adrenergic homogeneity. J Pharmacol Exp Ther. 306:1152–1158.
   PubMed Web of Science ®Google Scholar
• Callia ML, De Moraes S. 1984. Heterogeneity of beta-adrenoceptors in right atria isolated from cold-exposed rats. J Pharmacol Exp Ther. 230:450–454.
   PubMed Web of Science ®Google Scholar
• Carvalho MB, Bassani RA, Franchini KG, Bassani JWM. 2006. Enhanced calcium mobilization in rat ventricular myocytes during the onset of pressure overload-induced hypertrophy. Am J Physiol Heart Circ Physiol. 291:H1803–H1813.
   Web of Science ®Google Scholar
• Charmandari E, Tsigos C, Chrousos G. 2005. Endocrinology of the stress response. Annu Rev Physiol. 67:259–284.
   PubMed Web of Science ®Google Scholar
• Christ T, Galindo-Tovar A, Thoms M, Ravens U, Kaumann AJ. 2009. Inotropy and L-type Ca2+ current, activated by β1- and β2-adrenoceptors, are differently controlled y phosphodiesterases 3 and 4 in rat heart. Br J Pharmacol. 156:62–85.
   PubMed Web of Science ®Google Scholar
• Daly JW. 2000. Alkylxanthines as research tools. J Auton Nervous Syst. 81:44–52.
   PubMedGoogle Scholar
• DeSantiago J, Ai X, Islam M, Acuna G, Ziolo MT, Bers DM, Pogwizd SM. 2008. Arrhythmogenic effects of β2-adrenergic stimulation in the failing heart are attributable to enhanced sarcoplasmic reticulum Ca load. Circ Res. 102:1389–1397.
   PubMed Web of Science ®Google Scholar
• Díaz ME, Trafford AW, O'Neill SC, Eisner DA. 1997. A measurable reduction of s.r. Ca content follows spontaneous Ca release in rat ventricular myocytes. Pflügers Arch Eur J Physiol. 434:852–854.
   PubMed Web of Science ®Google Scholar
• Donald DE, Shepherd JT. 1963. Response to exercise in dogs with cardiac denervation. Am J Physiol. 205:393–400.
   PubMed Web of Science ®Google Scholar
• Fuji AM, Vatner SF. 1985. Autonomic mechanisms regulating myocardial contractility in conscious animals. Pharmacol Ther. 29:221–238.
   PubMed Web of Science ®Google Scholar
• Fujiwara K, Tanaka H, Mani H, Nakagami T, Takamatsu T. 2008. Burst emergence of intracellular Ca2+ waves evokes arrhythmogenic oscillatory depolarization via the Na+-Ca2+ exchanger. Circ Res. 103:509–518.
   PubMed Web of Science ®Google Scholar
• Galindo-Tovar A, Kaumann AJ. 2008. Phosphodiesterase-4 blunts inotropism and arrhythmias but not sinoatrial tachycardia of (-)-adrenaline mediated through mouse cardiac β1-adrenoceptors. Br J Pharmacol. 153:710–720.
   PubMed Web of Science ®Google Scholar
• Ginsburg KS, Bers DM. 2004. Modulation of excitation-contraction coupling by isoproterenol in cardiomyocytes with controlled SR Ca2+ load and Ca2+ current trigger. J Physiol. 556:463–480.
   PubMed Web of Science ®Google Scholar
• Jo SH, Leblais V, Wang PH, Crow MT, Xiao RP. 2002. Phosphatidylinositol 3-kinase functionally compartmentalizes the concurrent Gs signaling during β2-adrenergic stimulation. Circ Res. 91:46–53.
   PubMed Web of Science ®Google Scholar
• Juberg EN, Minneman KP, Abel PW. 1985. Beta-1 and beta-2 adrenoceptor binding and functional response in right and left atria of the rat heart. Naunyn Schmiedeberg Arch Pharmacol. 330:193–202.
   PubMed Web of Science ®Google Scholar
• Kerfant BG, Zhao D, Lorenzen-Schmidt I, Wilson LS, Cai S, Chen SRW, Maurice DH, Backx PH. 2007. PI3Kγ is required for PDE4, not PDE3, activity in subcellular microdomains containing the sarcoplasmic reticulum calcium ATPase in cardiomyocytes. Circ Res. 101:400–408.
   PubMed Web of Science ®Google Scholar
• ter Keurs HEDJ, Boyden PA. 2007. Calcium and arrhythmogenesis. Physiol Rev. 87:457–586.
   PubMed Web of Science ®Google Scholar
• Kitagawa Y, Adachi-Akahane S, Nagao T. 1995. Determination of β-adrenoceptor subtype on rat isolated ventricular myocytes by use of highly-selective β-antagonists. Br J Pharmacol. 116:1635–1643.
   PubMed Web of Science ®Google Scholar
• Kontula K, Laitinen PJ, Lehtonen A, Toivonen L, Viitasalo M, Swan H. 2005. Catecholaminergic polymorphic ventricular tachycardia: Recent mechanistic insights. Cardiovasc Res. 67:379–387.
   PubMed Web of Science ®Google Scholar
• Lane RD, Laukes C, Marcus FI, Chesney MA, Sechrest L, Gear K, Fort CL, Priori SG, Schwartz PJ, Steptoe A. 2005. Psychological stress preceding idiopathic ventricular fibrillation. Psychosom Med. 67:359–365.
   PubMed Web of Science ®Google Scholar
• Leblais V, Jo SH, Chakir K, Maltsev V, Zheng M, Crow MT, Wang W, Lakatta EG, Xiao RP. 2004. Phosphatidylinositol 3-kinase offsets cAMP-mediated positive inotropic effect via inhibiting Ca2+ influx in cardiomyoyctes. Circ Res. 95:1183–1190.
   PubMed Web of Science ®Google Scholar
• Li Y, Kranias EG, Mignery GA, Bers DM. 2002. Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes. Circ Res. 90:309–316.
   PubMed Web of Science ®Google Scholar
• Lukyanenko V, Subramanian S, Györke I, Wiesner TF, Györke S. 1999. The role of luminal Ca in the generation of Ca waves in rat ventricular myocytes. J Physiol. 518:173–186.
   PubMed Web of Science ®Google Scholar
• Müller FU, Neumann J, Schmitz W. 2000. Transcriptional regulation by cAMP in the heart. Mol Cell Biochem. 212:11–17.
   PubMed Web of Science ®Google Scholar
• Nikolaev VO, Bünemann M, Schmitteckert E, Lohse MJ, Engelhardt D. 2006. Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching β1-adrenergic but locally confined β2-adrenergic receptor-mediated signaling. Circ Res. 99:1084–1091.
   PubMed Web of Science ®Google Scholar
• Patrucco E, Notte A, Barberis L, Selvetella G, Maffei A, Brancaccio M, Marengo S, Russo G, Azzolino O, Rybalkin SD, . 2004. PI3Kγ modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and independent effects. Cell. 118:375–387.
   PubMed Web of Science ®Google Scholar
• Pogwizd SM, Schlottauer L, Li L, Weilong Y, Bers DM. 2001. Arrhythmogenesis and contractile dysfunction in heart failure. Circ Res. 88:1150–1167.
   Google Scholar
• Ranu HK, Mak JCW, Barnes PJ, Harding SE. 2000. Gi-dependent suppression of β1-adrenoceptor effects in ventricular myocytes from NE-treated guinea-pigs. Am J Physiol Heart Circ Physiol. 278:H1807–H1814.
   Web of Science ®Google Scholar
• Santos IN, Spadari-Bratfisch RC. 2006. Stress and cardiac beta-adrenoceptors. Stress. 9:69–84.
   PubMed Web of Science ®Google Scholar
• Silveira AC, Gilioli R, Oliveira ES, Bassani RA. 2003. Subsensitivity to beta-adrenergic stimulation in atria from rats infested with Syphacia sp. Lab Anim. 37:63–67.
   PubMedGoogle Scholar
• Spadari RC, De Moraes S. 1988. Repeated swimming stress and responsiveness of the isolated rat pacemaker to the chronotropic effect of noradrenaline and isoprenaline: Role of adrenal corticosteroids. Gen Pharmacol. 19:553–557.
   PubMedGoogle Scholar
• Steinberg SF, Alcott S, Pak E, Hu D, Protas L, Möise NS, Robinson RB, Rosen MR. 2002. β1-receptors increase cAMP and induce abnormal Ca cycling in the German shepherd sudden death model. Am J Physiol Heart Circ Physiol. 282:H1181–H1188.
   Web of Science ®Google Scholar
• Vargas ML, Hernandez J, Kaumann AJ. 2006. Phosphodiesterase PDE3 blunts the positive inotropic and cyclic AMP enhancing effects of CGP12177 but not of noradrenaline in rat ventricle. Br J Pharmacol. 147:158–163.
   PubMed Web of Science ®Google Scholar
• Venetucci LA, Trafford AE, Díaz ME, O'Neill SC, Eisner DA. 2006. Reducing ryanodine receptor open probability as a means to abolish spontaneous Ca2+ release and increase Ca2+ transient amplitude in adult ventricular myocytes. Circ Res. 98:1299–1305.
   PubMed Web of Science ®Google Scholar
• Xiao RP, Zhu W, Zheng M, Cao C, Zhang Y, Lakatta EG, Han Q. 2006. Subtype-specific α1- and β-adrenoceptor signaling in the heart. TIPS. 27:330–337.
   PubMed Web of Science ®Google Scholar
• Zalk R, Lehnart SE, Marks AS. 2007. Modulation of the ryanodine receptor and intracellular calcium. Annu Rev Biochem. 76:367–385.
   Google Scholar