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REVIEW ARTICLE

Health effects of World Trade Center (WTC) Dust: An unprecedented disaster with inadequate risk management

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Pages 492-530 | Received 03 Mar 2015, Accepted 21 Apr 2015, Published online: 10 Jun 2015

References

  • ACGIH. (1984). Particle Size-Selective Sampling in the Workplace. Cincinnati OH, American Conference of Governmental Industrial Hygienists. Publication # 830.
  • ACGIH. (2014). Appendix B, Particles (Insoluble or poorly soluble) Not Otherwise Specified (PNOS) of: 2014 TLVs and BEIs for Chemical Substances. Cincinnati OH, American Conference of Governmental Industrial Hygienists. ISBN: 978–1-607260–72-1.
  • Albert RE, Spiegelman JR, Shatsky S, Lippmann M. (1969a). The effect of acute exposure to cigarette smoke on bronchial clearance in the miniature donkey. Arch Environ Health, 18, 30–41.
  • Albert RE, Lippmann M, Briscoe, W. (1969b). The characteristics of bronchial clearance in humans and the effects of cigarette smoking. Arch Environ Health, 18, 738–55.
  • Albert RE, Peterson HT Jr, Bohning DE, Lippmann M. (1975). Short-term effects of cigarette smoking on bronchial clearance in humans. Arch Environ Health, 30, 361–67.
  • Antao VC, Pallos LL, Shim YK, Sapp JH II, Brackbill RM, Cone JE, et al. (2011). Respiratory protective equipment, mask use, and respiratory outcomes among World Trade Center rescue and recovery workers. Am J Ind Med, 54, 897–905.
  • ATSDR. (2002). New York Department of Health and Mental Hygiene and Agency for Toxic Substances and Disease Registry. Final Technical Report of the Public Health Investigation to Assess Potential Exposures to Airborne and Settled Surface Dust in Residential Areas of Lower Manhattan. Agency for Toxic Substances and Disease Registry, US Department of Health and Human Services, Atlanta, GA. (http://www.atsdr.cdc.gov/asbestos/asbestos˙WTC.html).
  • Banauch G, McLaughlin M, Hirschhorn R, Corrigan M, Kelly K, Prezant D. (2002). Injuries and illnesses among New York City Fire Department rescue workers after responding to the World Trade Center attacks. MMWR Morb Mortal Wkly Rep, 51, 1–5.
  • Banauch GI, Alleyne D, Sanchez R, Olender K, Cohen HW, Weiden M, et al. (2003). Persistent hyperreactivity and reactive airway dysfunction in firefighters at the World Trade Center. Am J Respir Crit Care Med, 168, 54–62.
  • Banauch GI, Dhala A, Alleyne D, Alva R, Santhyadka G, Krasko A, et al. (2005a). Bronchial hyperreactivity and other inhalation lung injuries in rescue/recovery workers after the World Trade Center collapse. Crit Care Med, 33, S102–6.
  • Banauch GI, Dhala A, Prezant DJ. (2005b). Pulmonary disease in rescue workers at the World Trade Center site. Curr Opin Pulm Med, 11, 160–8.
  • Banauch G, Hall C, Weiden M, Cohen H, Aldrich T, Christodoulou V, et al. (2006). Pulmonary function after exposure to the World Trade Center collapse in the New York City Fire Department. Am J Respir Crit Care Med, 174, 312–9.
  • Baxter PK, Searl AS, Cowie HA, Jarvis D, Horwell CJ. (2014). Evaluating the respiratory health risks of volcanic ash at the eruption of the Soufrière Hills Volcano, Montserrat, 1995 to 2010. Memoirs of theGeological Society of London, 39, 407–25.
  • Berkowitz GS, Wolff MS, Janevic TM, Holzman IR, Yehuda R, Landrigan PJ. (2003). The World Trade Center disaster and intrauterine growth restriction. JAMA, 290, 595–6.
  • Bernard BP, Baron SL, Mueller CA, Driscoll RJ, Tapp LC, Wallingford KM, Tepper AL. (2002). Impact of September 11 attacks on workers in the vicinity of the World Trade Center–New York City. MMWR Morb Mortal Wkly Rep, 51, 8–10.
  • Bohning DE, Albert RE, Lippmann M, Foster WM. (1975). Tracheobronchial particle deposition and clearance. A study of the effects of cigarette smoking in monozygotic twins. Arch Environ Health, 30, 457–62.
  • Boscarino JA, Galea S, Ahern J, Resnick H, Vlahov D. (2003). Psychotic medication use among Manhattan residents following the World Trade Center disaster. J Traum Stress, 16, 301–6.
  • Bowers B, Hosni S, Gruber BL. (2010). Sarcoidosis in World Trade Center rescue workers presenting with rheumatologic manifestations. J Clin Rheumatol, 16, 26–7.
  • Brackbill RM, Hadler JL, DiGrande L, Ekenga CC, Farfel MR, Friedman S, et al. (2009). Asthma and posttraumatic stress symptoms 5 to 6 years following exposure to the World Trade Center terrorist attack. JAMA, 302, 502–16.
  • Brackbill RM, Thorpe L, DiGrande L, Perrin M, Sapp J, Wu D, et al. (2006). Surveillance for World Trade Center disaster health effects among survivors of collapsed and damaged buildings. MMWR Surveill Summ, 55, 1–18.
  • Briant JK, Lippmann M. (1992). Particle transport through a hollow canine airway cast by high-frequency oscillatory ventilation. Exp. Lung Res, 18, 385–407.
  • Briant JK, Lippmann M. (1993). Aerosol bolus transport through a hollow airway cast by steady flow in different gases. Aerosol Sci Technol, 19, 27–39.
  • Buist AS, Bernstein RS (eds). (1986). Health effects of volcanoes: an approach to evaluating the health effects of an environmental hazard. Am J Public Health, 76, 1–90.
  • Buyantseva LV, Tulchinsky M, Kapalka GM, Chinchilli VM, Qian Z, Gillio R, et al. (2007). Evolution of lower respiratory symptoms in New York police officers after 9/11: a prospective longitudinal study. J Occup Environ Med, 49, 310–17.
  • Chatfield EJ, Kominsky JR. (2001). Summary report: characterization of particulate found in apartments after destruction of the world trade center. Requested by “GZ” Elected Officials Task Force comprised of: U.S. Congressman Jerrold Nadler, Manhattan Borough President Virginia Fields, and 7 other New York State and New York City Officials. Available at http://www.eqm.com.
  • Chen L, Thurston G. (2002). World Trade Center cough. Lancet (suppl), 360, 37–38.
  • Cho S, Echevarria G, Kwon S, Naveed B, Schenck EJ, Tsukiji J, et al. (2014). One airway: biomarkers of protection from upper and lower airway injury after WTC Dust exposure. Respir Med, 108, 162–70.
  • Cohen BS, Harley NH, Lippmann M. (1984). Bias in air sampling techniques used to measure inhalation exposure. Am Ind Hyg Assoc J, 45, 187–92.
  • Cohen MD, Vaughan JM, Garrett B, Prophete C, Horton L, Sisco M, et al. (2014). Acute high-level exposure to WTC particles alters expression of genes associated with oxidative stress and immune function in the lung. J Immunotoxicol , 12, 140–53. doi:10.3109/1547691X.2014.914609).
  • Cohen MD, Vaughan JM, Garrett B, Prophete, C, Horton, L, Sisco M, et al. (2015). Impact of acute exposure to WTC dust on ciliated and goblet cells in lungs of rats. Inhalation Toxicology (in press).
  • Debchoudhury I, Welch AE, Fairclough MA, Cone JE, Brackbill RM, Stellman SD, Farfel MR. (2011). Comparison of health outcomes among affiliated and lay disaster volunteers enrolled in the World Trade Center Health Registry. Preventive Medicine, 53, 359–63.
  • de la Hoz RE, Christie J, Teamer JA, Bienenfeld LA, Afilaka AA, Crane M, et al. (2008). Reflux symptoms and disorders and pulmonary disease in former World Trade Center rescue and recovery workers and volunteers. J Occup Environ Med, 50, 1351–4.
  • Enterline PE, Marsh GM, Esmen NA. (1983). Respiratory disease among workers exposed to man-made mineral fibers. Am Rev Resp Dis, 128, 1–7.
  • EPA. (2002). Exposure and Human Health Evaluation of Airborne Pollution from the World Trade Center. EPA/600/P-2/002A, National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency.
  • Fagan J, Galea S, Ahern J, Bonner S, Vlahov D. (2002). Self-reported increase in asthma severity after the September 11 attacks on the World Trade Center–Manhattan, New York, 2001. MMWR Morb Mortal Wkly Rep, 51, 781–4.
  • Fairbrother G, Stuber J, Galea S, Fleischman AR, Pfefferbaum B. (2003). Posttraumatic stress reactions in New York City children after the September 11, 2001, terrorist attacks. Ambul Pediatr, 3, 304–11.
  • Farfel M, Digrande L, Brackbill R, Prann A, Cone J, Friedman S, et al. (2008). An overview of 9/11 experiences and respiratory and mental health conditions among World Trade Center Health Registry enrollees. J Urban Health, 85, 880–909.
  • Feldman DM, Baron S, Bernard B, Lushniak B, Banauch G, Arcentales N, et al. (2004). Symptoms, respirator use, and pulmonary function changes among New York City firefighters responding to the World Trade Center disaster. Chest, 125, 1256–64.
  • Ferrier N, Nolan A, Naveed B, Rom WN, Comfort AL, Prezant DJ, Weiden MD. (2011). Low serum IgA and IgG4 levels predict accelerated decline in lung function Of WTC Dust-exposed firefighters. Am J Respir Crit Care Med, 183, A4773.
  • Fireman EM, Lerman Y, Ganor E, Greif J, Fireman-Shoresh S, Lioy PJ, et al. (2004). Induced sputum assessment in New York City firefighters exposed to World Trade Center dust. Environ Health Perspect, 112, 1564–9.
  • Friedman SM, Farfel MR, Maslow CB, Con JE, Brackbill RM, Stellman SD. (2013). Comorbid persistent lower respiratory symptoms and posttraumatic stress disorder 5–6 years post-9/11 in responders enrolled in the World Trade Center Health Registry. Am J Ind Med, 56, 1251–61.
  • Galea S, Vlahov D, Resnick H, Ahern J, Susser E, Gold J, Bucuvalas D. (2003). Trends of probable post-traumatic stress disorder in New York City after the September 11 terrorist attacks. Amer J Epidemiol, 158, 514–24.
  • GAO Report. (2004). Health Effects in the Aftermath of the World Trade Center Attack. GAO-04–1068 T US Governmental Accountability Office.
  • Gavett S, Haykal-Coates N, Highfill J, Ledbetter A, Chen L-C, Cohen M, et al. (2003). World Trade Center fine particulate matter causes respiratory tract hyperresponsiveness in mice. Environ Health Perspect, 111, 981–91.
  • Geyh AS, Chillrud S, Williams DI, Herbstman J, Symons JM, Rees K, et al. (2005). Assessing truck driver exposure at the World Trade Center disaster site: personal and area monitoring for particulate matter and volatile organic compounds during October 2001 and April 2002. J Occup Environ Hyg, 2, 179–93.
  • Green DC, Buehler JW, Silk BJ, Thompson NJ, Schild LA, Klein M, Berkelman RL. (2006). Trends in healthcare use in the New York City region following the Terrorist Attacks of 2001. Biosecur Bioterror, 4, 263–75.
  • Guidotti TL, Prezant D, de la Hoz RE, Miller A. (2011). The evolving spectrum of pulmonary disease in responders to the World Trade Center tragedy. Am J Ind Med, 54, 649–60.
  • Herbert R, Moline J, Skloot G, Metzger K, Baron S, Luft B, et al. (2006). The World Trade Center disaster and the health of workers: five-year assessment of a unique medical screening program. Env Health Perspect, 114, 1853–8.
  • Herbstman JB, Frank R, Schwab M, Williams D, Samet J, Breysse P, et al. (2005). Respiratory effects of inhalation exposure among workers during the clean- up effort at the World Trade Center disaster site. Environ Res, 99, 85–92.
  • Howard J. (2014). WTC health program, health conditions medically associated with World Trade Center-related health conditions. Washington, DC: NIOSH.
  • Jordan HT, Stellman SD, Prezant D, Teirstein A, Osahan SS, Cone JE. (2011). Sarcoidosis diagnosed after September 11, 2001, among adults exposed to the World Trade Center disaster. J Occup Environ Med, 53, 966–74.
  • Kazeros A, Maa MT, Patrawalla P, Liu M, Shao Y, Qian M, et al. (2013). Elevated peripheral eosinophils are associated with new-onset and persistent wheeze and airflow obstruction in world trade center-exposed individuals. J Asthma, 50, 25–32.
  • Kim H, Herbert R, Landrigan P, Markowitz SB, Moline JM, Savitz DA, et al. (2012). Increased rates of asthma among World Trade Center disaster responders. Am J Ind Med, 55, 44–53.
  • Kleinman EJ, Cucco RA, Martinez C, Romanelli J, Berkowitz I, Lanes N, et al. (2011a). Erratum: pulmonary function in a cohort of New York City Police Department emergency responders since the 2001 World Trade Center disaster. J Occup Environ Med, 53, 1086.
  • Kleinman EJ, Cucco RA, Martinez C, Romanelli J, Berkowitz I, Lanes N, et al. (2011b). Pulmonary function in a cohort of New York City Police Department emergency responders since the 2001 World Trade Center disaster. J Occup Environ Med, 53, 618–26.
  • Kwon S, Weiden MD, Echevarria GC, Comfort AL, Naveed B, Prezant DJ, et al. (2013). Early elevation of serum MMP-3 and MMP-12 predicts protection from World Trade Center lung injury in New York City firefighters: a nested case-control study. Plos One, 8, e76099.
  • Landrigan PJ, Lioy, PJ, Thurston G, Berkowitz G, Chen LC, Chillrud SN, et al. (2004). The NIEHS World Trade Center Working Group. Health and environmental consequences of the World Trade Center disaster . Environ Health Perspect, 112, 731–9.
  • Laumbach RJ, Harris G, Kipen HM, Georgopoulos P, Shade P, Isukapalli SS, et al. (2009). Lack of association between estimated World Trade Center plume intensity and respiratory symptoms among New York City residents outside of Lower Manhattan. Am J Epidemiol, 170, 640–9.
  • Lederman SA, Rauh V, Weiss L, Stein JL, Hoepner LA, Becker M, Perera FP. (2004). The effects of the World Trade Center event on birth outcomes among term deliveries at three lower Manhattan hospitals. Environ Health Perspect, 112, 1772–8.
  • Lee RJ. (2014). Personal communication of technical analyses performed by RJ Lee Group, Inc. Monroeville, PA, 2002–2004 for a commercial building impacted by WTC Dust.
  • Leikauf G, Yeates DB, Wales KA, Spektor D, Albert RE, Lippmann M. (1981). Effects of sulfuric acid aerosol on respiratory mechanics and mucociliary clearance in healthy nonsmoking adults. Am Ind Hyg Assoc J, 42, 273–82.
  • Leikauf GD, Spektor DM, Albert RE, Lippmann M. (1984). Dose-dependent effects of submicrometer sulfuric acid aerosol on particle clearance from ciliated human lung airways. Am Ind Hyg Assoc J, 45, 285–92.
  • Levin SM, Herbert R, Moline JM, Todd AC, Stevenson L, Landsbergis P, et al. (2004). Physical health status of World Trade Center rescue and recovery workers and volunteers–New York City, July 2002-August 2004. MMWR Morb Mortal Wkly Rep, 53, 807–12.
  • Levin S, Herbert R, Skloot G, Szeinuk T, Fishler D, Milek, D, et al. (2002). Health effects of World Trade Center site workers. Am J Ind Med, 42, 545–7.
  • Li J, Brackbill RM, Stellman SD, Farfel MR, Miller-Archie SA, Friedman S, et al. (2011). Gastroesophageal reflux symptoms and comorbid asthma and posttraumatic stress disorder following the 9/11 terrorist attacks on World Trade Center in New York City. Am J Gastroenterol, 106, 1933–41.
  • Lin S, Reibman J, Bowers JA, Hwang S, Hoerning A, Gomez ML, Fitzgerald EF. (2005). Upper respiratory symptoms and other health effects among residents living near the World Trade Center site after September 11, 2001. Am J Epidemiol, 162, 499–507.
  • Lin S, Jones R, Reibman J, Bowers J, Fitzgerald EF, Hwang SA. (2007). Reported respiratory symptoms and adverse home conditions after 9/11 among residents living near the World Trade Center. J Asthma, 44, 325–32.
  • Lin S, Gomez MI, Gensburg L, Liu W. Hwang SA. (2010a). Respiratory and cardiovascular hospitalizations after the World Trade Center disaster. Arch Environ Occup Health, 65, 12–20.
  • Lin S, Jones R, Reibman J, Morse D, Hwang SA. (2010b). Lower respiratory symptoms among residents living near the World Trade Center, two and four years after 9/11. Int J Occup Environ Health, 16, 44–52.
  • Lioy PJ, Weisel CP, Millette JR, Eisenreich S, Vallero D, Offenberg J, et al. (2002). Characterization of the dust/smoke aerosol that settled east of the World Trade Center (WTC) in Lower Manhattan after the collapse of the WTC 11 September 2001. Env Health Perspect, 110, 703–14.
  • Lioy PJ, Pellizzari E, Prezant D. (2006). The World Trade Center aftermath and its effects on health: understanding and learning through human-exposure science. Environ Sci Technol, 40, 6876–85.
  • Lippmann M, Albert RE. (1969). The effect of particle size on the regional deposition of inhaled aerosols in the human respiratory tract. Am Ind Hyg Assoc J, 30, 257–75.
  • Lippmann, M. (1977). Regional deposition of particles in the human respiratory tract. In: Lee DHK, Falk HL, Murphy SD, Eds. Handbook of Physiology, Section 9: Reactions to Environmental Agents. Bethesda, MD: American Physiological Society, pp. 213–32.
  • Lippmann M, Timbrell V. (1990). Particle loading in the human lung–human experience and implications for exposure limits. J Aerosol Med, 3, S155–68.
  • Lippmann M, Schlesinger RB, Leikauf G, Spektor D, Albert RE. (1982). Effects of sulphuric acid aerosols on the respiratory tract airways. Ann Occup Hyg, 26, 677–90.
  • Lippmann M, Schlesinger, RB. (1984). Interspecies comparisons of particle deposition and mucociliary clearance in tracheobronchial airways. J Toxicol Environ Health, 13, 441–69.
  • Lippmann M, Chen LC. (2007). Particle deposition and pulmonary defense mechanisms. In: WN Rom, SB Markowitz, Eds. Environmental and Occupational Medicine, 4th Ed. Philadelphia: Lippincott, Williams & Wilkens, pp. 168–86.
  • Lippmann M. (2014a). Toxicological and epidemiological studies of effects of airborne fibers: coherence and public health implications. Crit Rev Toxicol, 44, 643–95.
  • Lippmann M. (2014b). Toxicological and epidemiological studies of cardiovascular effects of ambient air fine particulate matter (PM2.5) and its chemical components: coherence and public health implications. Crit Rev Toxicol, 44, 299–347.
  • Lorber M, Gibb H, Grant L, Pinto J, Pleil J, Cleverly D. (2007). Assessment of inhalation exposures and potential health risks to the general population that resulted from the collapse of the World Trade Center towers. Risk Anal, 27, 1203–21.
  • Lowers HA, Meeker GP, Lioy PJ, Lippmann M. (2009). Summary of the development of a signature for detection of residual dust from collapse of the World Trade center buildings. J Expos Sci Environ Epidemiol, 19, 325–35.
  • Luft BJ, Schecter C, Kotov R, Broihier J, Reissman D, Friedman Jimenez G, et al. (2012). Exposure, probable PTSD and lower respiratory illness among World Trade Center rescue, recovery and clean-up workers. Psychol Med, 42, 1069–79.
  • Maciejczyk PB, Zeisler RI, Hwang JS, Thurston GD, Chen LC. (2004). Characterization of size-fractionated World Trade Center dust and estimation of relative dust contribution to ambient particulate concentrations. In: Jeffrey SG, Nancy AM, Eds. Urban Aerosols and Their Impacts: Lessons learned from the World Trade Center Tragedy, Chapter 7: ACS Symposium Series 919, 114–31.
  • Malievskaya E, Rosenberg N, Markowitz S. (2002). Assessing the health of immigrant workers near Ground Zero: preliminary results of the World Trade Center Day Laborer Medical Monitoring Project. Am J Ind Med, 42, 548–9.
  • Maslow CB, Friedman SM, Pillai PS, Reibman J, Berger KJ, Goldring R, et al (2012). Chronic and acute exposures to the world trade center disaster and lower respiratory symptoms: area residents and workers. Am J Public Health, 102, 1186–94.
  • Mauer MP, Cumming KR. (2010a). Impulse oscillometry and respiratory symptoms in World Trade Center responders, 6 years post-9/11. Lung, 188, 107–13.
  • Mauer MP, Cummings KR, Carlson GA. (2007). Health effects in New York State personnel who responded to the World Trade Center disaster. J Occup Environ Med, 49, 1197–205.
  • Mauer MP, Cummings KR, Hoen R. (2010b). Long-term respiratory symptoms in World Trade Center responders. Occup Med (Lond), 60, 145–51.
  • Mauer MP, Herdt-Losavio ML, Carlson GA. (2010c). Asthma and lower respiratory symptoms in New York State employees who responded to the World Trade Center disaster. Int Arch Occup Environ Health, 83, 21–27.
  • McGee JK, Chen LC, Cohen MD, Chee GR, Prophete C, Haykal-Coates N, et al. (2003). Chemical analysis of World Trade Center fine particulate matter for use in toxicologic assessment. Environ Health Perspect, 111, 972–80.
  • McMahon JT, Aslam R, Schell SE. (2011). Unusual ciliary abnormalities in three 9/11 response workers. Ann Otol Rhinol Laryngol, 120, 40–48.
  • Meeker GP, Lioy PJ, Lippmann M, Lowers HA. (2010). Letter to the editor: response to the comment by Henry Kahn and Dennis Santella on a summary of the development of a signature for detection of residual dust from the collapse of the World Trade Center buildings. J. Expos. Sci. Environ. Epidemiol, 20, 491–492 (2010).
  • Meo SA. (2004). Health hazards of cement dust. Saudi Med J, 25, 1153–59.
  • Morrow PE. (1988). Possible mechanisms to explain dust overloading of the lungs. Fund Appl Toxicol, 10, 369–84.
  • Naveed B, Comfort AL, Ferrier N, Segal, LN, Kasturiarachchi, KJ, Kwon, S, et al. (2011b). WTC Dust induces GM-CSF in serum of FDNY rescue workers with accelerated decline of lung function and in cultured alveolar macrophages. Am J Respir Crit Care Medi, 183, A4770.
  • Naveed B, Weiden M, Rom WN, Prezant, DJ, Comfort, AL, Chen Y, et al. (2011a). WTC PM2.5 stimulates a more intense inflammatory response in human BAL cells than other ambient PM2.5 from NYC and surrounding environs. Am J Respir Crit Care Med, 183, A1158.
  • Niles JK, Webber MP, Gustave J, Cohen HW, Zeig-Owens R, Kelly K, et al. (2011). Comorbid trends in World Trade Center cough syndrome and probable posttraumatic stress disorder in firefighters. Chest, 140, 1146–54.
  • Nolan A, Naveed B, Comfort AL, Ferrier N, Hall CB, Kwon S, et al. (2012). Inflammatory biomarkers predict airflow obstruction after exposure to World Trade Center dust. Chest, 142, 412–8.
  • Nolan A, Kwon S, Cho S, Naveed B Comfort AL Prezant DJ et al. (2014). MMP-2 and TIMP-1 predict healing of WTC-lung injury in New York City firefighters. Respiratory Research, 15, 5.
  • Payne JP, Kemp SJ, Dewar CA, Goldstraw P, Kendall M, Chen LC, Tetley TD. (2004). Effects of airborne World Trade Center dust on cytokine release by primary human lung cells in vitro. J Occup Environ Med, 46, 420–7.
  • Prezant DJ, Weiden M, Banauch GI, McGuinness G, Rom WN, Aldrich TK, Kelly KJ. (2002). Cough and bronchial responsiveness in firefighters at the World Trade Center site. N Engl J Med, 347, 806–15.
  • Reibman J, Lin S, Hwang SA, Gulati M, Bowers JA, Rogers I, et al. (2005). The World Trade Center residents’ respiratory health study: new-onset respiratory symptoms and pulmonary function. Environ Health Perspect, 113, 406–11.
  • Reibman J, Liu M, Cheng Q, Liautaud S, Rogers L, Lau S, et al. (2009). Characteristics of a residential and working community with diverse exposure to World Trade Center dust, gas, and fumes. J Occup Environ Med, 51, 534–41.
  • Rom WN, Reibman J, Rogers L, Weiden MD, Oppenheimer B, Berger K, et al. (2010). Emerging exposures and respiratory health—World Trade Center dust. Proc Am Thorac Soc, 7, 142–5.
  • SAB. (1988a). Future Risk: Research Strategies for the 1990's. SAB-EC,-88–040. Washington, DC: Science Advisory Board, U.S. Environmental Protection Agency.
  • SAB. (1988b). Reducing Risk: Setting Priorities for Environmental Protection. SAB-EC,-90–021. Washington, DC: Science Advisory Board, U.S. Environmental Protection Agency.
  • SAB. (1995). Beyond the Horizon: Using Foresight to Protect the Environmental Future.EPA-SAB-EC-95–007. Washington, DC: Science Advisory Board, U.S. Environmental Protection Agency.
  • Salzman SH, Moosavy F, Miskoff J, Friedmann P, Fried G, Rosen M. (2004). Early respiratory abnormalities in emergency services police officers at the World Trade Center site. J Occup Environ Med, 46, 113–22.
  • Schenck EJ, Echevarria GC, Girvin FG, Kwon, S, Comfort, AL, Rom WN, et al. (2014). Enlarged pulmonary artery is predicted by vascular injury biomarkers and is associated with WTC-Lung Injury in exposed fire fighters: a case-control study. BMJ, 4, e005575.
  • Schlesinger RB, Lippmann M. (1978a). Selective particle deposition and bronchogenic carcinoma. Environ Res, 15, 424–31.
  • Schlesinger RB, Lippmann M, Albert RE. (1978b). Effects of short-term exposures to sulfuric acid and ammonium sulfate aerosols upon bronchial airway function in donkeys. Am Ind Hyg Assoc J, 39, 275–86.
  • Siebert WJ. (1942). Fiberglas health hazard investigation. Ind Med, 11, 6–9.
  • Skloot G, Goldman M, Fishler D, Goldman C, Schector C, Levin S, Teirstein, A. (2004). Respiratory symptoms and physiologic assessment of ironworkers at the World Trade Center disaster site. Chest, 125, 1248–55.
  • Spadafora R. (2002). Firefighter safety and health issues at the World Trade Center site. Am J Ind Med, 42, 532–8.
  • Spektor DM, Leikauf GD, Albert RE, Lippmann M. (1985). Effects of submicrometer sulfuric acid aerosols on mucociliary transport and respiratory mechanics in asymptomatic asthmatics. Environ Res, 37, 174–91.
  • Stokholm J, Norn M, Schneider T. (1982). Ophthamologic effects of man-made mineral fibers. Scand J Work Environ Health, 8, 185–90.
  • Sussman RG, Cohen BS, Lippmann M. (1991).Asbestos fiber deposition in a human tracheobronchial cast. II. Empirical model. Inhal Toxicol, 3, 161–79.
  • Tao XG, Massa J, Ashwell L, Davis K, Schwab M, Geyh A. (2007). The world trade center clean up and recovery worker cohort study: respiratory health amongst cleanup workers approximately 20 months after initial exposure at the disaster site. J Occup Environ Med, 49, 1063–72.
  • Tapp LC, Baron S, Bernard B, Driscoll R, Mueller C, Wallingford K. (2005). Physical and mental health symptoms among NYC transit workers seven and one-half months after the WTC attacks. Amer Indust Med, 47, 475–83.
  • Trout D, Nimgade A, Mueller C, Hall R, Earnest GS. (2002). Health effects and occupational exposures among office workers near the World Trade Center disaster site. J Occup Environ Med, 44, 601–5.
  • Udasin I, Schecter C, Crowley L, Sotolongo A, Gochfeld M, Luft B, et al. (2011). Respiratory symptoms were associated with lower spirometry results during the first examination of WTC responders. J Occup Environ Med, 53, 49–54.
  • USGS. (2002). September 11, 2001: Studying the Dust from the World Trade Center Collapse. USGS Fact Sheet F#-050–02. United States Geological Survey.
  • Vaughan JM, Garrett BJ, Prophete C, Horton L, Sisco M, Soukup JM, et al. (2014). A novel system to generate WTC dust particles for inhalation exposures. J Expo Sci Environ Epidemiol, 24, 105–12.
  • Wagner VL, Radigan MS, Roohan PJ, Anarella JP, Gesten FC. (2005). Asthma in Medicaid managed care enrollees residing in New York City: results from a post-World Trade Center disaster survey. J Urban Health, 82, 76–89.
  • Wang S, Prophete C, Soukup JM, Chen LC, Costa M, Ghio A, et al. (2010). Roles of MAPK pathway activation during cytokine induction in BEAS-2B cells exposed to fine World Trade Center (WTC) dust. J Immunotox, 7, 298–307.
  • Webber MP, Glaser MS, Weakley J, Soo J, Ye F, Zeig-Owens R, et al. (2011). Physician-diagnosed respiratory conditions and mental health symptoms 7–9 years following the World Trade Center disaster. Am J Ind Med, 54, 661–71.
  • Weiden MD, Ferrier N, Nolan A, Rom WN, Comfort A, Gustave J, et al. (2010). Obstructive airways disease with air trapping among firefighters exposed to World Trade Center dust. Chest, 137, 566–74.
  • Weiden MD, Naveed B, Kwon S, Segal, LN, Cho, SJ, Tsukiji, J, et al. (2012). Comparison of WTC dust size on macrophage inflammatory cytokine release in vivo and in vitro. PLoS One, 7, e40016.
  • Weiden M, Naveed B, Kwon S, Cho, SJ, Comfort, AL, Prezant, DJ, et al. (2013). Cardiovascular biomarkers predict susceptibility to lung injury in World Trade Center dust-exposed firefighters. Euro Respir J, 41, 1023–30.
  • Wisnivesky JP, Teitelbaum SL, Todd AC, Boffetta P, Crane M, Crowley L, et al. (2011). Persistence of multiple illnesses in World Trade Center rescue and recovery workers: a cohort study. Lancet, 378, 888–97.
  • Xu A, Prophete C, Chen L-C, Emala CW, Cohen MD. (2011). Interactive effect of cigarette smoke extract and World Trade Center dust particles on airway cell cytotoxicity. J Toxicol Environl Health, 74, 887–902.
  • Yiin L-M, Millette JR, Vette A, Ilacqua V, Quan C, Gorczynski J, et al. (2006). Comparisons of the dust/smoke particulate that settled inside the surrounding buildings and outside on the streets of southern New York City after the collapse of the World Trade center, September 11, 2001. J Air Waste Manage Assoc, 54, 515–28.
  • Zeleke ZK, Moen BE, Bråtveit M. (2010). Cement dust exposure and acute lung function: a cross shift study. BMC Pulmonary Medicine, 10, 19–26.

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