Hypertrophic Foci of Pancreatic Acinar Cells in Rats

References

• Cubilla A. L., Fitzgerald P. J. Cancer of the pancreas (nonendocrine): a suggested morphologic classification. Semin. Oncol. 1979; 6: 285
   PubMed Web of Science ®Google Scholar
• American Cancer Society. Cancer Facts & Figures 1984
   Google Scholar
• American Cancer Society. Cancer Facts & Figures 1981
   Google Scholar
• Moossa A. R. Pancreatic cancer: approach to diagnosis, selection for surgery and choice of operation. Cancer 1982; 50: 2689
   PubMedGoogle Scholar
• Dickhaus S., Reznik G., Green U., Ketkar M. The carcinogenic effect of beta-oxidized dipropylnitrosamine in mice. 1. Dipropylnitrosamine and methyl-propylnitrosamine. Z. Krebsforsch. 1977; 90: 253
   Google Scholar
• Dickhaus S., Reznik G., Green U., Ketkar M. The carcinogenic effect of β- oxidized dipropylnitrosamine in mice. II. 2-Hydroxypropyl-n-propylnitrosamine and 2-oxo-propyl-n-propylnitrosamine. Z. Krebsforsch. 1978; 91: 189
   Google Scholar
• Zimmerman J. A., Trombetta L. D., Carter T. H., Weisbroth S. H. Pancreatic carcinoma induced byN-methyl-N'-nitrosourea in aged mice. Gerontology 1982; 28: 114
   Google Scholar
• Corbett T. H., Roberts B. J., Leopold W. R., Peckham J. C., Wilkoff L. J., Griswold D. P., Jr., Schabel F. M., Jr. Induction and chemotherapeutic response of two transplantable ductal adenocarcinoma of the pancreas in C57BL/6 mice. Cancer Res. 1984; 44: 717
   PubMed Web of Science ®Google Scholar
• Bockman D. E., Black O., Jr., Mills L. R., Mainz D. L., Webster P. D., III. Fine structure of pancreatic adenocarcinoma induced in rats by 7,12-dimethylbenz(a)anthracene. J. Natl. Cancer Inst. 1976; 57: 931
   PubMedGoogle Scholar
• Bockman D. E., Black O., Jr., Mills L. R., Webster P. D. Origin of tubular complexes developing during induction of pancreatic adenocarcinoma by 7,12-dimethylbenz(a)anthracene. Am. J. Pathol. 1978; 90: 645
   PubMed Web of Science ®Google Scholar
• Bücheler J., Thomas C. Experimentell erzeugte Drüsenmagentumoren bei Meerschweinchen und Ratte. Beitr. Pathol. 1971; 142: 194
   Google Scholar
• Denda A., Inui S., Sunagawa M., Takahashi S., Konishi Y. Enhancing effect of partial pancreatectomy and ethionine-induced pancreatic regeneration on the tumorigenesis of azaserine in rats. Gann 1978; 69: 633
   Google Scholar
• Denda A., Yokose Y., Emi Y., Murata Y., Ohara T., Sunagawa M., Mikami S., Takahashi S., Konishi Y. Effects of caffeine on pancreatic tumorigenesis by 4-hydroxyaminoquinoline 1-oxide in partially pancreatectomized rats. Carcinogenesis 1983; 4: 17
   PubMed Web of Science ®Google Scholar
• Dissin J., Mills L. R., Mains D. L., Black O., Jr., Webster P. D., III. Experimental induction of pancreatic adenocarcinoma in rats. J. Natl. Cancer Inst. 1975; 55: 857
   PubMedGoogle Scholar
• Hastings P. R., Beazley R. M., Cohn I. Progress with pancreatic cancer. Progress in Clinical Cancer, Vol. 8, I. M. Ariel. Grune & Stratton, New York 1982; 319.
   Google Scholar
• Hayashi Y., Furukawa H., Hasegawa T. Pancreatic tumors in rats induced by 4-nitroquinoline 1-oxide derivatives. Topics in Chemical Carcinogenesis, W. Nakahara, S. Takayama, T. Sugimura, T. Odashima. University Park Press, Baltimore 1972; 53.
   Google Scholar
• Hayashi Y., Hasegawa T. Experimental pancreatic tumor in rats after intravenous injection of 4-hydroxyaminoquinoline 1-oxide. Gann 1971; 62: 329
   Google Scholar
• Hayashi Y., Katayama H. Promoting effect of testosterone propionate on experimental exocrine pancreatic tumors by 4-hydroxyaminoquinoline 1-oxide in rats. Toxicol. Lett. 1981; 9: 349
   PubMedGoogle Scholar
• Hendry J. A., Matthews J. J., Walpole A. L., Williams M. H. C. Tumours induced in rats with 4′-fluoro-4-aminodiphenyl. Nature (London) 1955; 175: 1131
   Google Scholar
• Hoch-Ligeti C. Primary pancreatic tumours in rats fedp-dimethylaminoazobenzene. Br. J. Cancer 1949; 3: 285
   Google Scholar
• Konishi Y., Denda A., Inui S., Takahashi S., Kondo H. Pancreatic carcinoma induced by 4-hydroxyaminoquinoline 1-oxide after partial pancreatectomy and splenectomy in rats. Gann 1976; 67: 919
   PubMedGoogle Scholar
• Konishi Y., Denda A., Inui S., Takahashi S., Ueda N., Namiki M. Production of pancreatic acinar cell carcinoma by combined administration of 4-hydroxyaminoquinoline 1-oxide and azaserine in partial pancreatectomized rats. Cancer Lett. 1978; 4: 229
   PubMed Web of Science ®Google Scholar
• Konishi Y., Denda A., Miyata Y., Kawabata H. Enhancement of pancreatic tumorigenesis of 4-hydroxyaminoquinoline 1-oxide by ethionine in rats. Gann 1976; 67: 91
   PubMedGoogle Scholar
• Levison D. A., Morgan R. G. H., Brimacombe J. S., Hopwood D., Coghill G., Wormsley K. G. Carcinogenic effects of di(2-hydroxypropyl)nitrosamine (DHPN) in male Wistar rats: promotion of pancreatic cancer by a raw soya flour diet. Scand. J. Gastroenterol. 1979; 14: 217
   PubMed Web of Science ®Google Scholar
• Longnecker D. S. Carcinoma of the pancreas in azaserine-treated rats (Abstr.). Fed. Proc. 1975; 34: 827
   Google Scholar
• Longnecker D. S. Carcinoma of the pancreas in azaserine-treated rats. Am. J. Pathol. 1981; 105: 94
   Google Scholar
• Longnecker D. S. Carcinogenesis in the pancreas. Arch. Pathol. Lab. Med. 1983; 107: 54
   PubMed Web of Science ®Google Scholar
• Longnecker D. S., Crawford B. G. Hyperplastic nodules and adenomas of exocrine pancreas in azaserine-treated rats. J. Natl. Cancer Inst. 1974; 53: 573
   Google Scholar
• Longnecker D. S., Curphey T. J. Adenocarcinoma of the pancreas in azaserine-treated rats. Cancer Res. 1975; 35: 2249
   PubMed Web of Science ®Google Scholar
• Longnecker D. S., Curphey T. J., Lilja H. S., French J. I., Daniel D. S. Carcinogenicity in rats of the nitrosourea amino acidNσ-(N-methyl-N-nitrosocarbamoyl)-L-ornithine. J. Environ. Pathol. Toxicol. 1980; 4: 117
   Google Scholar
• Longnecker D. S., Roebuck B. D., Yager J. D., Lilja H. S., Siegmund B. Pancreatic carcinoma in azaserine-treated rats: induction, classification, and dietary modulation of incidence. Cancer 1981; 47: 1562
   Google Scholar
• Milman H. A., Ward J. M., Chu K. C. Pancreatic carcinogenesis and naturally occurring pancreatic neoplasms of rats and mice in the NCI carcinogenesis testing program. J. Environ. Pathol. Toxicol. 1978; 1: 829
   Google Scholar
• Mohr U., Reznik G., Pour P. Carcinogenic effects of diisopropanolnitrosamine in Sprague-Dawley rats. J. Natl. Cancer Inst. 1977; 58: 361
   PubMedGoogle Scholar
• Morgan R. G. H., Wormsley K. G. Cancer of the pancreas. Gut 1977; 18: 580
   PubMed Web of Science ®Google Scholar
• Reddy J. K., Rao M. S. Transplantable pancreatic carcinoma of the rat. Science 1977; 198: 78
   PubMedGoogle Scholar
• Reddy J. K., Scarpelli D. G., Rao M. A. Experimental pancreatic carcinogenesis. Advances in Medical Onocology, Research and Education, Vol. 9, N. Thatcher. Pergamon Press, New York 1979; 99.
   Google Scholar
• Roebuck B. D., Lilja H. S., Curphey T. J., Longnecker D. S. Pathologic and biochemical effects of azaserine in inbred Wistar/Lewis rats and noninbred CD®-1 mice. J. Natl. Cancer Inst. 1980; 65: 383
   PubMedGoogle Scholar
• Roebuck B. D., Yager J. D., Jr., Longnecker D. S., Wilpone S. A. Promotion by unsaturated fat of azaserine-induced pancreatic carcinogenesis in the rat. Cancer Res. 1981; 41: 3961
   PubMedGoogle Scholar
• Stewart H. L., Snell K. C., Morris H. P. The combined effect of 3-methylcholanthrene andN,N'-2,7-fluorenylenebisacetamide on the induction of cancer of the glandular stomach of the rat. J. Natl. Cancer Inst. 1965; 34: 157
   PubMedGoogle Scholar
• Umeyama K., Satake K., Yamashita K., Yamamoto S., Kamino K., Sowa M. Pancreatic carcinoma in rats induced by 7,12-dimethylbenzanthracene. Pathophysiology of Carcinogenesis in Digestive Organs, Proc. 7th Int. Symp. Princess Takamatsu Cancer Research Fund, E. Farber, T. Kawachi, T. Nagayo, H. Sugano, T. Sugimura, J. H. Weisburger. University Park Press, Baltimore 1977; 385.
   Google Scholar
• Flaks B., Moore M. A., Flaks A. Ultrastructural analysis of pancreatic carcinogenesis: morphological characterization ofN-nitroso-bis(2-hydroxypropyl)amine-induced neoplasms in the Syrian hamster. Cancinogenesis 1980; 1: 423
   Google Scholar
• Konishi Y., Takahashi S., Sunagawa M., Miyagi N., Kondo H. Heterotransplanatation into nude mice of pancreatic carcinoma induced byN-bis(2-hydroxypropyl) nitrosamine in hamsters. Cancer Lett. 1978; 5: 333
   Google Scholar
• Longnecker D. S., Curphey T. J., French J. I., Lilja H. S. Response of the Syrian golden hamster to a nitrosourea amino acid carcinogen. Cancer Lett. 1979; 8: 163
   Google Scholar
• Mohr U., Reznik G., Emminger E., Lijinsky W. Induction of pancreatic duct carcinomas in the Syrian hamster with 2,6-dimethylnitrosomorphine. J. Natl. Cancer Inst. 1977; 58: 429
   Google Scholar
• Moore M. A., Takahashi M., Ito N., Bannasch P. Early lesions during pancreatic carcinogenesis induced in Syrian hamster by DHPN or DOPN. I. Histologic, histochemical, and radioautographic findings. Carcinogenesis 1983; 4: 431
   Google Scholar
• Pour P. M., Birt D. F. Modifying factors in pancreatic carcinogenesis in the hamster model. IV. Effect of dietary protein. J. Natl. Cancer Inst. 1983; 71: 347
   PubMedGoogle Scholar
• Pour P. M., Donnelly T., Stepan K., Muffly K. Modification of pancreatic carcinogenesis in the hamster model. II. The effect of partial pancreatectomy. Am. J. Pathol. 1983; 110: 75
   Google Scholar
• Pour P. M., Nagel D., Lawson T. Carcinogenicity ofN-nitrosomethyl(2-oxobutyl)amine andN-nitrosomethyl(3-oxobutyl)amine in Syrian hamsters with special reference to the pancreas. Cancer Res. 1983; 43: 4885
   Google Scholar
• Pour P. M., Runge R. G., Birt D., Gingell R., Lawson T., Nagel D., Wallcave L., Salmasi S. Z. Current knowledge of pancreatic carcinogenesis in the hamster and its relevance to the human disease. Cancer 1981; 47: 1573
   PubMed Web of Science ®Google Scholar
• Reznik G., Mohr U., Lijinsky W. Carcinogenic effect ofN-nitroso-2,6-dimethylmorphine in Syrian golden hamsters. J. Natl. Cancer Inst. 1978; 60: 371
   Google Scholar
• Sindelar W. F., Kurman C. C. Nitrosamine-induced pancreatic carcinogenesis in outbred and inbred Syrian hamsters. Carcinogenesis 1982; 3: 1021
   Google Scholar
• Druckrey H., Ivankovic S., Bücheler J., Preussmann R., Thomas C. Erzeugung von Magenund Pankreas-Krebs beim Meerschweinchen durch Methynitroso-harnstoff und -urethan. Z. Krebsforsch. 1968; 72: 167
   Google Scholar
• Reddy J. K., Rao M. S. Pancreatic adenocarcinoma in inbred guinea pigs induced byN-methyl-N-nitrosourea. Cancer Res. 1975; 35: 2269
   PubMed Web of Science ®Google Scholar
• Reddy J. K., Svoboda D. J., Rao M. S. Susceptibility of an inbred strain of guinea pigs to the induction of pancreatic adenocarcinoma byN-methyl-N-nitrosourea. J. Natl. Cancer Inst. 1974; 52: 991
   Google Scholar
• Roebuck B. D., Longnecker D. S. Response of two rodents, Mastomys natalensis and Mystromys albicaudatus, to the pancreatic carcinogen azaserine. J. Natl. Cancer Inst. 1979; 62: 1269
   Google Scholar
• Elkort R. J., Handler A. H., Mozden P. J. Preneoplastic changes in rabbit pancreatic duct cells produced by dimethylhydrazine. Int. J. Cancer 1975; 16: 810
   Google Scholar
• Elkort R. J., Handler A. H., Williams D. L. Early neoplasia of rabbit pancreatic ductal cells induced by dimethylhydrazine. Cancer Res. 1975; 35: 2292
   Google Scholar
• Longnecker D. S., French J., Hyde E., Lilja H. S., Yager J. D., Jr. Effect of age on nodule induction by azaserine and DNA synthesis in rat pancreas. J. Natl. Cancer Inst. 1977; 58: 1769
   PubMedGoogle Scholar
• Roebuck B. D., Baumgartner K. J., Thron C. D. Characterization of two populations of pancreatic atypical acinar cell foci induced by azaserine in the rat. Lab. Invest. 1984; 50: 141
   Google Scholar
• Roebuck B. D., Longnecker D. S. Species and rat strain variation in pancreatic nodule induction by azaserine. J. Natl. Cancer Inst. 1977; 59: 1273
   PubMed Web of Science ®Google Scholar
• Zurlo J., Longnecker D. S., Cooney D. A., Kuhlmann E. T., Curphey T. J. Studies of pancreatic nodule induction and DNA damage by D-azaserine. Cancer Lett. 1981; 12: 75
   Google Scholar
• Morris H. P., Wagner B. P., Ray F. E., Snell K. C., Stewart H. L. Comparative study of cancer and other lesions of rats fedN,N'-2,7-fluorenylenebisacetamide orN-2-fluorenylacetamide. Natl. Cancer Inst. Monogr. 1961; 5: 1
   Google Scholar
• Morris H. P., Wagner B. P., Ray F. E., Steward H. L., Snell K. C. Comparative carcinogenic effects ofN,N'-2,7-fluorenylenebisacetamide by intraperitoneal and oral routes of administration to rats, with particular reference to gastric carcinoma. J. Natl. Cancer Inst. 1962; 29: 997
   Google Scholar
• Rao M. S., Subbarao V., Scarpelli D. G. Sequential histological analysis of the rat pancreas treated with a single dose of 4-hydroxyaminoquinoline-1-oxide (4-HAQO) (abstr.). Fed. Proc. 1983; 42: 781
   Google Scholar
• Rao M. S., Upton M. P., Subbarao V., Scarpelli D. G. Two populations of cells with differing proliferative capacities in atypical acinar cell foci induced by 4-hydroxyaminoquinoline-1-oxide in the rat pancreas. Lab. Invest. 1982; 46: 527
   PubMedGoogle Scholar
• Shinozuka H., Konishi Y. Degenerative and hyperplastic changes in rat pancreatic acinar cells induced by 4-hydroxyaminoquinoline-1-oxide (Abstr.). Am. J. Pathol. 1974; 74: 59a
   Google Scholar
• Shinozuka H., Popp J. A., Konishi Y. Ultrastructures of atypical acinar cell nodules in rat pancreas induced by 4-hydroxyaminoquinoline-1-oxide. Lab. Invest. 1976; 34: 501
   Google Scholar
• Anver M. R., Cohen B. J., Lattuada C. P., Foster S. J. Age-associated lesions in barrier-reared male Sprague-Dawley rats: a comparison between Hap: (SD) and Crl:COBSRCDR (SD) stocks. Exp. Aging Res. 1982; 8: 3
   PubMed Web of Science ®Google Scholar
• Berg B. N. Longevity studies in rats. II. Pathology of aging rats. Pathology of Laboratory Rats and Mice, E. Cotchin, F. J. C. Roe. Blackwell Scientific, Oxford 1967, chap. 23.
   Google Scholar
• Boorman G. A., Hollander C. F. Spontaneous lesions in the female WAG/Rij (Wistar) rat. J. Gerontol. 1973; 28: 152
   Google Scholar
• Burek J. D. Pathology of Aging Rats. CRC Press, Boca Raton, Fla. 1978, chap. 4.
   Google Scholar
• Cohen B. J., Anver M. R., Ringler D. H., Adelman R. C. Age-associated pathological changes in male rats. Fed. Proc. 1978; 37: 2848
   PubMedGoogle Scholar
• Coleman G. L., Barthold S. W., Osbaldiston G. W., Foster S. J., Jonas A. M. Pathological changes during aging in barrier-reared Fisher 344 male rats. J. Gerontol. 1977; 32: 258
   PubMedGoogle Scholar
• Crain R. Spontaneous tumors in the Rochester strain of the Wistar rat. Am. J. Pathol. 1958; 34: 311
   PubMed Web of Science ®Google Scholar
• Gilbert C., Gillman J. Spontaneous neoplasms in the albino rat. S. Afr. J. Med. Sci. 1958; 23: 257
   Google Scholar
• Goodman D. G., Ward J. M., Squire R. A., Chu K. C., Linhart M. S. Neoplastic and nonneoplastic lesions in aging F344 rats. Toxicol. Appl. Pharmacol. 1979; 48: 237
   PubMed Web of Science ®Google Scholar
• Goodman D. G., Ward J. M., Squire R. A., Paxton M. B., Reichardt W. D., Chu K. C., Linhart M. S. Neoplastic and nonneoplastic lesions in aging Osborne-Mendel rats. Toxicol. Appl. Pharmacol. 1980; 55: 433
   PubMed Web of Science ®Google Scholar
• Kroes R., Garbis-Berkvens J. M., De Vries T., Van Nesselrooy J. H. J. Histopathological profile of a Wistar rat stock including a survey of the literature. J. Gerontol. 1981; 36: 259
   PubMedGoogle Scholar
• Löhrke H., Hesse B., Goerttler K. Spontaneous tumors in male and female specified pathogenfree Sprague-Dawley rats (outbred stock Sut:SDT). Z. Versuchstierk 1982; 24: 225
   Google Scholar
• Mac Kenzie W. F., Garner F. M. Comparison of neoplasms in six sources of rats. J. Natl. Cancer Inst. 1973; 50: 1243
   Google Scholar
• Maekawa A., Kurokawa Y., Takahashi M., Kokubo T., Ogiu T., Onodera H., Tanigawa H., Ohno Y., Furukawa F., Hayashi Y. Spontaneous tumors in F-344/DuCrj rats. Gann 1983; 74: 365
   PubMedGoogle Scholar
• Morii S., Fujii T. Spontaneous tumors in Sprague-Dawley JCL rats. Jikken Dobutsu 1973; 22: 127
   Google Scholar
• Muraoka Y., Itoh M., Maeda Y., Hayashi Y. Histological changes of various organs in aged SD-JCL rats. Jikken Dobutsu 1977; 26: 1
   Google Scholar
• Muraoka Y., Itoh M., Yamashita F., Hayashi Y. Spontaneous tumors in aged SD-JCL rats. Jikken Dobutsu 1977; 26: 13
   Google Scholar
• Prejean J. D., Peckham J. C., Casey A. E., Griswold D. P., Weisburger E. K., Weisburger J. H. Spontaneous tumors in Sprague-Dawley rats and Swiss mice. Cancer Res. 1973; 33: 2768
   PubMed Web of Science ®Google Scholar
• Rowlatt U. F. Pancreatic neoplasm of rats and mice. Pathology of Laboratory Rats and Mice, E. Cotchin, F. J. C. Roe. Blackwell Scientific, Oxford 1967, chap. 4.
   Google Scholar
• Rowlatt U., Roe F. J. C. Epithelial tumors of the rat pancreas. J. Natl. Cancer Inst. 1967; 39: 18
   Google Scholar
• Sass B., Rabstein L. S., Madison R., Nims R. M., Peters R. L., Kelloff G. J. Incidence of spontaneous neoplasm in F344 rats throughout the natural life-span. J. Natl. Cancer Inst. 1975; 54: 1449
   PubMedGoogle Scholar
• Schardein J. L., Fitzgerald J. E., Kaump D. H. Spontaneous tumors in Holtzman-source rats of various ages. Pathol. Vet. 1968; 5: 238
   PubMedGoogle Scholar
• Snell K. C. Spontaneous lesions of the rat. Pathology of Laboratory Animals, W. E. Ribelin, J. R. McCoy. Charles C Thomas, Springfield, III. 1965, chap. 10.
   Google Scholar
• Thompson S. W., Huseby R. A., Fox M. A., Davis C. L., Hunt R. D. Spontaneous tumors in the Sprague-Dawley rat. J. Natl. Cancer Inst. 1961; 27: 1037
   PubMed Web of Science ®Google Scholar
• Chiu T. Spontaneous hypertrophic foci of pancreatic acinar cells in CD rats. Toxicol. Pathol. 1983; 11: 115
   Google Scholar
• Shinozuka H., Katyal S. L., Lombardi B. Azaserine carcinogenesis: organ susceptibility change in rats fed a diet devoid of choline. Int. J. Cancer 1978; 22: 36
   PubMed Web of Science ®Google Scholar
• Shinozuka H., Katyal S. L. Further characterization of atypical acinar cell nodules (AACN) of the pancreas in carcinogen treated rats (abstr.). Fed. Proc. 1979; 38: 1403
   Google Scholar
• Longnecker D. S., Crawford B. G., Nadler D. J. Recovery of pancreas from mild puromycin-induced injury: a histologic and ultrastructure study in rats. Arch. Pathol. 1975; 99: 5
   Google Scholar
• Longnecker D. S., Farber E. Acute pancreatic necrosis induced by puromycin. Lab. Invest. 1967; 16: 321
   Google Scholar
• Hruban Z., Swift H., Slesers A. Effects of azaserine on the fine structure of the liver and pancreatic acinar cells. Cancer Res. 1965; 25: 708
   Google Scholar
• Konishi Y., Popp J. A., Shinozuka H. Pancreatic acinar cell damage induced by 4-nitroquinoline-1-oxide and 4-hydroxyaminoquinoline-1-oxide. J. Natl. Cancer Inst. 1974; 52: 917
   PubMedGoogle Scholar
• Rao M. S., Reddy J. K. 4-Hydroxyaminoquinoline-1-oxide-induced ultrastructural changes in the guinea pig exocrine pancreas. J. Pathol. 1976; 120: 109
   Google Scholar
• Reddy J. K., Rao M. S., Svoboda D. J., Prasad J. D. Pancreatic necrosis and regeneration induced by 4-hydroxyaminoquinoline-1-oxide in the guinea pig. Lab. Invest. 1975; 32: 98
   PubMed Web of Science ®Google Scholar
• Longnecker D. S., Zurlo J., Curphey T. J., Adams W. E. Induction of pancreatic DNA damage and nodules in rats treated withN-nitrosobis(2-oxopropyl)amine andN-nitroso (2-hydroxypropyl)(2-oxopropyl)amine. Carcinogenesis 1982; 3: 715
   Google Scholar
• Longnecker D. S. personal communication 1983
   Google Scholar
• Chiu T. unpublished data. E. I. du Pont de Nemours and Co., Inc., Haskell Laboratory for Toxicology and Industrial Medicine, Newark, Del. 1976
   Google Scholar
• Chiu T. unpublished data. E. I. du Pont de Nemours and Co., Inc., Haskell Laboratory for Toxicology and Industrial Medicine, Newark, Del. 1983
   Google Scholar
• Takahashi M., Pour P. Spontaneous alterations in the pancreas of the aging Syrian golden hamster. J. Natl. Cancer Inst. 1978; 60: 355
   Google Scholar
• Hosoda S., Suzuki H., Suzuki M. Spontaneous tumors and atypical proliferation of pancreatic acinar cells in Mastomys (Praomys) natalensis. J. Natl. Cancer Inst. 1976; 57: 1341
   Google Scholar
• Solleveld H. A., Van Zwieten M. J., Zurcher C., Hollander C. F. A histopathological survey of aged Praomys (Mastomys) natalensis. J. Gerontol. 1982; 37: 656
   PubMedGoogle Scholar
• Longnecker D. S., Kuhlmann E. T., Curphey T. J. Effects of four retinoids inN-nitrosobis(2-oxoproyl)amine-treated hamster. Cancer Res. 1983; 43: 3226
   Google Scholar
• Shinozuka H. personal communication 1983
   Google Scholar
• Hollander C. F., Higginson J. Spontaneous cancers in Praomys (Mastomys) natalensis. J. Natl. Cancer Inst. 1971; 46: 1343
   Google Scholar
• Longnecker D. S., Shinozuka H., Dekker A. Focal acinar cell dysplasia in human pancreas. Cancer 1980; 45: 534
   Google Scholar
• Shinozuka H., Lee R. E., Dunn J. L., Longnecker D. S. Multiple atypical acinar cell nodules of the pancreas. Hum. Pathol. 1980; 11: 389
   Google Scholar
• Leong A.-Y. S., Liew S.-H. Atypical acinar nodules and islet cell proliferation. Hum. Pathol. 1981; 12: 582
   PubMedGoogle Scholar
• Kodama T., Mori W. Atypical acinar cell nodules of the human pancreas. Acta Pathol. Jpn. 1983; 33: 701
   Google Scholar
• National Cancer Institute. Report of a workshop on classification of specific hepatocellular lesions in rats. Cancer Res. 1975; 35: 3214
   Google Scholar
• Institute of Laboratory Animal Resources, National Research Council, National Academy of Sciences. Histologic typing of liver tumors of the rat. J. Natl. Cancer Inst. 1980; 64: 179
   Google Scholar
• Longnecker D. S. Experimental pancreatic carcinogenesis. Lab. Invest. 1982; 46: 543
   Google Scholar
• McMartin D. N. Morphologic lesions in againg Syrian hamsters. J. Gerontol. 1979; 34: 502
   PubMedGoogle Scholar
• Pour P., Mohr U., Cardesa A., Altholf J., Kmoch N. Spontaneous tumors and common diseases in two colonies of Syrian hamsters. II. Respiratory tract and digestive system. J. Natl. Cancer Inst. 1976; 56: 937
   PubMedGoogle Scholar
• Pour P., Althoff J., Salmasi S. Z., Stepan K. Spontaneous tumors and common diseases in three types of hamster. J. Natl. Cancer Inst. 1979; 63: 797
   PubMed Web of Science ®Google Scholar
• Yager J. D., Roebuck B. D., Zurlo J., Longnecker D. S., Weselcouch E. O., Wilpone S. A. A single-dose protocol for azaserine initiation of pancreatic carcinogenesis in the rat. Int. J. Cancer 1981; 28: 601
   Google Scholar
• Pour P. M., Birt D. F., Salmasi S. Z., Götz U. Modifying factors in pancreatic carcinogenesis in the hamster model. I. Effect of protein-free diet fed during the early stages of carcinogenesis. J. Natl. Cancer Inst. 1983; 70: 141
   Google Scholar
• Birt D. F., Stepan K. R., Pour P. M. Interactin of dietary fat and protein on pancreatic carcinogenesis in Syrian golden hamsters. J. Natl. Cancer Inst. 1983; 71: 355
   PubMedGoogle Scholar
• Morgan R. G. H., Levinson D. A., Hopwood D., Saunders J. H. B., Wormsley K. G. Potentiation of the action of azaserine on the rat pancreas by raw soya bean flour. Cancer Lett. 1977; 3: 87
   PubMedGoogle Scholar
• Birt D. F., Salmasi S., Pour P. M. Enhancement of experimental pancreatic cancer in Syrian golden hamsters by dietary fat. J. Natl. Cancer Inst. 1981; 67: 1327
   PubMedGoogle Scholar
• National Toxicology Program. Board of Scientific Counselors' Meeting. Summary Minutes, Status Report on NIEHS/NTP Investigation of Exocrine Pancreatic Lesions in F344 Rats. March 14 and 15, 1983, 1
   Google Scholar
• O'Connor T. P., Youngman L. D., Campbell T. C. Effect of selenium on development of L-azaserine (Aza) induced preneoplastic abnormal acinar cell nodules (AACN) in rat pancreas (abstr.). Fed. Proc. 1983; 42: 670
   Google Scholar
• Longnecker D. S., Kuhlmann E. T., Curphey T. J. Divergent effects of retinoids on pancreatic and liver carcinogenesis in azaserine-treated rats. Cancer Res. 1983; 43: 3219
   PubMed Web of Science ®Google Scholar
• Pour P. M., Reber H. A., Stepan K. Modification of pancreatic carcinogenesis in the hamster model. XII. Dose-related effect of ethanol. J. Natl. Cancer Inst. 1983; 71: 1085
   Google Scholar
• Solomon T. E., Petersen H., Elashoff J., Grossman M. I. Interaction of caerulein and secretion on pancreatic size and composition in rat. Am. J. Physiol. 1978; 235: E714
   PubMedGoogle Scholar