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Research Article

Styrene: Toxicity Studies — What Do They Show?

Pages s117-s125 | Published online: 20 Oct 2008

References

  • Beliles R. P., Butala J. H., Stack C. R., Makris S. Chronic toxicity and three-generation reproduction study of styrene monomer in the drinking water of rats. Fundam. Appl. Toxicol 1985; 5: 855
  • Bond G. G., Bodner K. M., Olsen G. W., Cook R. R. Mortality among workers engaged in the development and manufacture of styrene-based products — an update. Scand. J. Work Environ. Health 1992; 18: 145
  • Brown N. A. Reproductive and developmental tox-icity of styrene. Reprod. Toxicol 1991; 5: 3
  • Butterworth B. E., Goldsworthy T. L., Popp J. A., McClellan R. O. The rodent cancer test: an assay under siege. CII Act. 1991; 11: 1
  • Coggon D., Osmand C., Pannett B., Simmonds S., Winter P. D., Acheson E. D. Mortality of workers exposed to styrene in the manufacture of glass-reinforced plastics. Scand. J. Work Environ. Health 1987; 13: 94
  • Conti B., Maltoni C., Perino G., Ciliberti A. Long-term carcinogenicity bioassays on styrene administered by inhalation, ingestion and injection and styrene oxide administered by ingestion in Sprague-Dawley rats, and para-methylstyrene administered by ingestion in Sprague-Dawley rats and Swiss mice. Ann. N.Y. Acad. Sci 1988; 534: 203
  • Hodgson J. T., Jones R. D. Mortality of styrene production, polymerization and processing workers at a site in northeast England. Scand. J. Work Environ. Health 1985; 11: 347
  • Jersey G. C., Balmer M. F., Quast J. F., Park C. N., Schuetz D. N., Beyer J. E., McCollister S., Rampy L. Two Year Chronic Inhalation Toxic-ity and Carcinogenicity Study of Monomeric Styrene in Rats. Chemical Manufacturer Association. 1978, Final Rep. CMA No. Sty 1.1-Tox. Inh.
  • Lijinski W. Rat and mouse forestomach tumors induced by chronic oral administration of styrene oxide. J. Natl. Cancer Inst. 1986; 77: 471
  • Maltoni C., Failla G., Kassapidis S. First experimental demonstration of the carcinogenic effects of styrene oxide. Med. Lav. 1979; 5: 358
  • Maltoni C., Giberti A., Carrietti D. Experimental contributions in identifying brain potential carcinogens in the petrochemical industry. Ann. N.Y. Acad. Sci. 1982; 381: 216, as cited in NCI, 1985
  • Matanoski G. M., Santos-Burgoa C., Schwartz L. Mortality of a cohort in the styrene-butadiene polymer manufacturing industry (1943-1982). Environ. Health Perspect 1990; 86: 107
  • Meinhardt T. J., Lemen R. A., Crandall M. S., Young R. J. Environmental epidemiologic investigation of the styrene-butadiene rubber industry: mortality patterns with discussion of the hematopoi-etic and lymphatic malignancies. Scand. J. Work Environ. Health 1982; 4: 247, (Suppl. 2)
  • NCI, National Cancer Institute Bioassay of a Solution of B-Nitrostyrene and Styrene for Possible Carcinogenicity. U.S. Department of Health, Education and Welfare National Institute of Health, Bethesda, MD 1978, CAS No. 102-965, CAS No. 100-42-5, NIH Rep. No. 79-1726
  • NCI, National Cancer Institute Bioassay of Styrene for Possible Carcinogenicity. U.S. Department of Health, Education and Welfare, National Institutes of Health, Bethesda, MD 1979, CAS No. 100-42-5, NCI-CG-TR-185, NIH Rep. No. 79-1741
  • Nicholson W. J., Selikoff I. J., Seidman H. Mortality experience of styrene-polystyrene polymerization workers: initial findings. Scand. J. Work Environ. Health 1978; 4: 247, (Suppl. 2)
  • Okun A. H., Beaumont J. J., Meinhardt T. J., Crandall M. S. Mortality patterns among sty-rene-exposed boatbuilders. Am. J. Ind. Med. 1985; 8: 193
  • Phillips D. H. Evidence for DNA Binding by Styrene and Styrene Oxide 1993, unpublished report
  • Ponomarkov V., Tomatis L. Effects of long-term oral administration of styrene to mice and rats. Scand. J. Work Environ. Health 1978; 4: 127, (Suppl. 2)
  • Ponomarkov V., Tomatis L. A carcinogenicity study of styrene-7,8 oxide in rats. Cancer Lett. 1984; 24: 95
  • Roe F. J. C. What does carcinogenicity mean and how should one test for it?. Food Chem. Toxicol. 1993; 31: 225
  • Van Duuren B. L. Carcinogenicity of epoxides, lactones and peroxy compounds. J. Natl. Cancer Inst. 1963; 31: 41
  • Weil C. S. Experimental carcinogenicity and acute toxicity of representative epoxides. Am. Ind. Hyg. Assoc. J. 1963; 24: 305
  • Wong O. A cohort mortality study and a casexontrol study of workers potentially exposed to styrene in the reinforced plastics and composites industry. Br. J. Ind. Med. 1990; 47: 753

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