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Original Article

Preliminary Experience with a New Chemotherapy Regimen for Adults with Acute Lymphoblastic Leukemia

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Pages 297-307 | Received 10 Aug 2000, Published online: 01 Jul 2009

References

  • Laport G. F., Larson R. A. Treatment of adult acute lymphoblastic leukemia. Semin Oncol 1997; 24: 70–82
  • Larson R. A., Dodge R. K., Burns C. P., Lee E. L., Stone R. M., Schulman P., Duggan D., Davey F. R., Sobol R. E., Frankel S. R., Hooberman A. L., Westbrook C. A., Arthur D. C., George S. L., Bloomfield C. D., Schiffer C. A. A five drug remission induction regimen with intensive consolidation for adults with acute lymphoblastic leukemia: Cancer and Leukemia Group B Study 8811. Blood 1995; 85: 2025–37
  • Larson R. A., Dodge R. K., Linker C. A., Stone R. M., Powell B. L., Lee E. J., Schulman P., Davey F. R., Frankel S. R., Bloomfield C. D., George S. L., Schiffer C. A. A randomized controlled trial of filgrastim during remission induction and consolidation chemotherapy for adults with acute lymphoblastic leukemia: CALGB Study 9111. Blood 1998; 92: 1556–64
  • Gale R. P., Hoelzer D. Acute Lymphoblastic Leukemia. Alan R. Liss, New York 1990; 221–9
  • Lauer S. J., Pinkel D., Buchanan G. R., Sartain P., Cornet J. M., Krance R., Borella L. D., Casper J. T., Kun L. E., Hoffman R. G. Cytosine arabinoside/cyclophosphamide pulses during continuation therapy for childhood acute lymphoblastic leukemia. Potential selective effect in T-cell leukemia. Cancer 1987; 60: 2366–71
  • Kamen B. Folate and antifolate pharmacology. Semin in Oncol 1997; 24(Suppl 18)S18–30
  • Gorlick R., Goker E., Trippett T., Steinherz P., Elisseyeff Y., Mazumdar M., Flintoff W. F., Bertino J. R. Decreased transport is a common mechanism of acquired methotrexate resistance in acute lymphoblastic leukemia and is associated with decreased reduced folate carrier expression. Blood 1997; 89: 1013–18
  • Whitehead V. M., Vuchich M. J., Cooley L. D., Lauer S. J., Mahoney D. A., Shuster J. J., Payment C., Koch P. A., Akabutu J. J., Bowen T., Kamen B. A., Ravindranath Y., Emami A., Look A. T., Beardsley G. P., Pullen D. J., Camitta B. Accumulation of methotrexate polyglutamates, ploidy, and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group Study. Leuk Lymphoma 1998; 31: 507–19
  • Synold T. W., Relling M. V., Boyett J. M., Rivera G. R., Sand-lund J. T., Mahmoud H., Crist W. M., Pui C. H., Evans W. E. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia. J Clin Invest 1994; 94: 1996–2001
  • Winnick N., Shuster J. J., Bowman P., Borowitz M., Farrow A., Jacaruso D., Buchanan G. R., Kamen B. A. Intensive oral methotrexate protects against lymphoid marrow relapse in childhood B-precursor acute lymphoblastic leukemia. J Clin Oncol 1996; 14: 2803–11
  • Goker E., Lin J. T., Trippett T., Elisseyeff Y., Tong W. P., Niedzwiecki D., Ton C., Steinherz P., Schweitzer B. I., Bertino J. R. Decreased polyglutamation of methotrexate in acute lymphoblastic leukemic blasts in adults compared to children with the disease. Leukemia 1993; 7: 1000–4
  • Sirotnak F. M., Moccio D. M., Dorick D. M. Optimization of high-dose methotrexate with leucovorin rescue in L21210 leukemia and sarcoma 180 murine tumor models. Cancer Research 1978; 38: 345–353
  • Spears C. P. Clinical resistance to antimetabolites. Hematology Oncology Clinics of North America 1995; 9: 397–413
  • Chabner B. Pharmacological Principles of Cancer Treatment. W. B. Saunders Co., Philadelphia 1982; 229–55
  • Cortes J., O'Brien S. M., Pierce S., Keating M. J., Freireich E. J., Kantarjian H. M. The value of high-dose systemic chemotherapy and intrathecal therapy for central nervous system prophylaxis in different risk groups of adult lymphoblastic leukemia. Blood 1995; 86: 2091–97
  • Frankel S. R., Kurtzberg J., DeOliveira R., Dodge B., Peterson B., Powell B. L., Kolitz J., Larson R. A., Schiffer C. A. Toxicity and pharmacokinetics of PEG-asparaginase in newly diagnosed adult acute lymphoblastic leukemia: CALGB 9511. Blood 1997; 90: 334a
  • Mandelli F., Annino L., Vegna M. L., Camera A., Ciolli S., Deplano W., Fabiano F., Ferrara F., Ladogana S., Muti G., Peta A., Recchia A., Sica S., Stassi R., Tabilio A., Visani G., Baccarani M. GIMEMA ALL 0288: a multi centric study on adult lymphoblastic leukemia. Preliminary results. Leukemia 1992; 6(Suppl 2)182–85
  • Ohno R. Granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating actor and macro- phage colony-stimulating factor in the treatment of acute myeloid leukemia and acute lymphoblastic leukemia. Leuk Res 1998; 22: 1143–54
  • Ottmann O. G., Hoelzer D. Growth factors in the treatment of acute lymphoblastic leukemia. Leuk Res 1998; 22: 1171–78

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