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Letters to the Editor

Coexistence of different types of biallelic immunoglobulin heavy variable gene replacement events in a case of pediatric B precursor acute lymphoblastic leukemia

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Pages 1748-1750 | Received 12 May 2010, Accepted 23 May 2010, Published online: 25 Jun 2010

References

  • Lefranc MP, Lefranc G. The immunoglobulin facts book. London: Academic Press; 2001.
  • Zhang Z, Burrows P, Cooper M. The molecular basis and biological significance of VH replacement. Immunol Rev 2004;197:231–242.
  • Davila M, Liu F, Cowell L, et al Multiple, conserved cryptic recombination signals in VH gene segments: detection of cleavage products only in pro-B cells. J Exp Med 2007;204:3195–3208.
  • Darlow J, Stott M. VH replacement in rearranged immunoglobulin genes. Immunology 2005;114:155–165.
  • Murray F, Darzentas N, Hadzidimitriou A, et al Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis. Blood 2008;111:1524–1533.
  • Choi Y, Greenberg S, Du TL, et al Clonal evolution in B-lineage acute lymphoblastic leukemia by contemporaneous VH-VH gene replacements and VH-DJH gene rearrangements. Blood 1996;87:2506–2512.
  • Steenbergen EJ, Verhagen OJ, van den Berg H, et al Rearrangement status of the malignant cell determines type of secondary IgH rearrangement (V-replacement or V to DJ joining) in childhood B precursor acute lymphoblastic leukemia. Leukemia 1997;11:1258–1265.
  • Koralov S, Novobrantseva T, Konigsmann J, Ehlich A, Rajewsky K. Antibody repertoires generated by VH replacement and direct VH to JH joining. Immunity 2006;25:43–53.

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