Chronic fatigue is prevalent and associated with hormonal dysfunction in long-term non-Hodgkin lymphoma survivors treated with radiotherapy to the head and neck region

References

• Bower JE. Cancer-related fatigue – mechanisms, risk factors, and treatments. Nat Rev Clin Oncol 2014;11:597–609.
   PubMed Web of Science ®Google Scholar
• Minton O, Berger A, Barsevick A, et al. Cancer-related fatigue and its impact on functioning. Cancer 2013;119(Suppl. 11): 2124–2130.
   PubMed Web of Science ®Google Scholar
• Oerlemans S, Mols F, Issa DE, et al. A high level of fatigue among long-term survivors of non-Hodgkin's lymphoma: results from the longitudinal population-based PROFILES registry in the south of the Netherlands. Haematologica 2013;98:479–486.
   PubMed Web of Science ®Google Scholar
• Jensen RE, Arora NK, Bellizzi KM, et al. Health-related quality of life among survivors of aggressive non-Hodgkin lymphoma. Cancer 2013;119(3):67–80.
   Web of Science ®Google Scholar
• Stone PC, Minton O. Cancer-related fatigue. Eur J Cancer 2008;44:1097–1104.
   PubMed Web of Science ®Google Scholar
• Brown LF, Kroenke K. Cancer-related fatigue and its associations with depression and anxiety: a systematic review. Psychosomatics 2009;50:440–447.
   PubMed Web of Science ®Google Scholar
• Brown LF, Rand KL, Bigatti SM, et al. Longitudinal relationships between fatigue and depression in cancer patients with depression and/or pain. Health Psychol 2013;32:1199–1208.
   PubMed Web of Science ®Google Scholar
• Mitchell SA, Berger AM. Cancer-related fatigue: the evidence base for assessment and management. Cancer J 2006;12:374–387.
   PubMed Web of Science ®Google Scholar
• Moser EC, Noordijk EM, Carde P, et al. Late non-neoplastic events in patients with aggressive non-Hodgkin's lymphoma in four randomized European Organisation for Research and Treatment of Cancer trials. Clin Lymphoma Myeloma 2005;6:122–130.
   PubMedGoogle Scholar
• Loge JH, Ekeberg O, Kaasa S. Fatigue in the general Norwegian population: normative data and associations. J Psychosom Res 1998;45(1 Spec No):53–65.
   PubMed Web of Science ®Google Scholar
• Stava CJ, Jimenez C, Vassilopoulou-Sellin R. Endocrine sequelae of cancer and cancer treatments. J Cancer Surviv 2007;1:261–274.
   PubMedGoogle Scholar
• Kaltsas G, Vgontzas A, Chrousos G. Fatigue, endocrinopathies, and metabolic disorders. PM R 2010;2:393–398.
   PubMedGoogle Scholar
• Abrahamsen AF, Loge JH, Hannisdal E, et al. Late medical sequelae after therapy for supradiaphragmatic Hodgkin's disease. Acta Oncol 1999;38:511–515.
   PubMed Web of Science ®Google Scholar
• Kiserud CE, Fossa A, Bjoro T, et al. Gonadal function in male patients after treatment for malignant lymphomas, with emphasis on chemotherapy. Br J Cancer 2009;100:455–463.
   PubMed Web of Science ®Google Scholar
• Greenfield DM, Walters SJ, Coleman RE, et al. Quality of life, self-esteem, fatigue, and sexual function in young men after cancer: a controlled cross-sectional study. Cancer 2010;116:1592–1601.
   PubMed Web of Science ®Google Scholar
• Howell SJ, Radford JA, Smets EM, et al. Fatigue, sexual function and mood following treatment for haematological malignancy: the impact of mild Leydig cell dysfunction. Br J Cancer 2000;82:789–793.
   PubMed Web of Science ®Google Scholar
• Kiserud CE, Seland M, Holte H, et al. Fatigue in male lymphoma survivors differs between diagnostic groups and is associated with latent hypothyroidism. Acta Oncol 2014;20:1–11.
   Google Scholar
• Knobel H, Havard LJ, Brit LM, et al. Late medical complications and fatigue in Hodgkin's disease survivors. J Clin Oncol 2001;19:3226–3233.
   PubMed Web of Science ®Google Scholar
• Stone P, Richardson A, Ream E, et al. Cancer-related fatigue: inevitable, unimportant and untreatable? Results of a multi-centre patient survey. Ann Oncol 2000;11:971–975.
   PubMed Web of Science ®Google Scholar
• Hjermstad MJ, Oldervoll L, Fossa SD, et al. Quality of life in long-term Hodgkin's disease survivors with chronic fatigue. Eur J Cancer 2006;42:327–333.
   PubMed Web of Science ®Google Scholar
• Abrahamsen AF, Loge JH, Hannisdal E, et al. Socio-medical situation for long-term survivors of Hodgkin’s disease: a survey of 459 patients treated at one institution. Eur J Cancer 1998;34: 1865–1870.
   PubMed Web of Science ®Google Scholar
• Minton O, Stone P. A systematic review of the scales used for the measurement of cancer-related fatigue (CRF). Ann Oncol 2009;20:17–25.
   PubMed Web of Science ®Google Scholar
• Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983;67:361–370.
   PubMed Web of Science ®Google Scholar
• Mykletun A, Stordal E, Dahl AA. Hospital Anxiety and Depression (HAD) scale: factor structure, item analyses and internal consistency in a large population. Br J Psychiatry 2001;179:540–544.
   PubMed Web of Science ®Google Scholar
• Ware JE, Jr., Gandek B. Overview of the SF-36 Health Survey and the International Quality of Life Assessment (IQOLA) Project. J Clin Epidemiol 1998;51:903–912.
   PubMed Web of Science ®Google Scholar
• Ware JE. SF-36 health survey update. Spine 2000;25:3130–3139.
   PubMed Web of Science ®Google Scholar
• Norwegian University of Science and Technology [Internet]; Available from: http://www.ntnu/hunt
   Google Scholar
• Bjerner J, Biernat D, Fossa SD, et al. Reference intervals for serum testosterone, SHBG, LH and FSH in males from the NORIP project. Scand J Clin Lab Invest 2009;69:873–879.
   PubMed Web of Science ®Google Scholar
• Blaes AH, Ma LA, Zhang Y, et al. Quality of life appears similar between survivors of indolent and aggressive non-Hodgkin lymphoma. Leuk Lymphoma 2011;52:2105–2110.
   PubMed Web of Science ®Google Scholar
• Ng AK, Li S, Recklitis C, et al. A comparison between long-term survivors of Hodgkin's disease and their siblings on fatigue level and factors predicting for increased fatigue. Ann Oncol 2005;16: 1949–1955.
   PubMed Web of Science ®Google Scholar
• Darzy KH, Shalet SM. Hypopituitarism as a consequence of brain tumours and radiotherapy. Pituitary 2005;8:203–211.
   PubMedGoogle Scholar
• Doga M, Bonadonna S, Gola M, et al. Growth hormone deficiency in the adult. Pituitary 2006;9:305–311.
   PubMedGoogle Scholar
• Bower JE, Ganz PA, Aziz N. Altered cortisol response to psychologic stress in breast cancer survivors with persistent fatigue. Psychosom Med 2005;67:277–280.
   PubMed Web of Science ®Google Scholar
• Bower JE, Ganz PA, Dickerson SS, et al. Diurnal cortisol rhythm and fatigue in breast cancer survivors. Psychoneuroendocrinology 2005;30:92–100.
   PubMed Web of Science ®Google Scholar
• Reuter K, Harter M. The concepts of fatigue and depression in cancer. Eur J Cancer Care (Engl) 2004;13:127–134.
   PubMed Web of Science ®Google Scholar
• Fobair P, Hoppe RT, Bloom J, et al. Psychosocial problems among survivors of Hodgkin's disease. J Clin Oncol 1986;4:805–814.
   PubMed Web of Science ®Google Scholar
• Ruffer JU, Flechtner H, Tralls P, et al. Fatigue in long-term survivors of Hodgkin's lymphoma; a report from the German Hodgkin Lymphoma Study Group (GHSG). Eur J Cancer 2003;39:2179–2186.
   PubMed Web of Science ®Google Scholar
• Bower JE, Bak K, Berger A, et al. Screening, assessment, and management of fatigue in adult survivors of cancer: an American Society of Clinical Oncology clinical practice guideline adaptation. J Clin Oncol 2014;32:1840–1850.
   PubMed Web of Science ®Google Scholar