Leukemia & Lymphoma, Volume 56, Issue 12 (2015)

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Leukemia & Lymphoma, Volume 56, Issue 12 (2015)

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Commentaries

Article Commentary
The continued conundrum of Hodgkin lymphoma etiology
Henrik Hjalgrim & Klaus Rostgaard
Pages: 3241-3242
Published online: 18 Jun 2015
CitationforThe continued conundrum of Hodgkin lymphoma etiology | Full Text | References | PDF (179.2 KB) | Supplemental
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Article Commentary
Improving the outcome of bloodstream infection in patients with hematological malignancies: looking beyond antibiotics
Monica A. Slavin & Karin A. Thursky
Pages: 3243-3245
Published online: 28 Aug 2015
First Page PreviewforImproving the outcome of bloodstream infection in patients with hematological malignancies: looking beyond antibiotics | Full Text | References | PDF (191.7 KB) | Supplemental
  • 218 Views
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Article Commentary
Prevention of thromboembolism in myeloma: expanding the tool-box of assays to predict the risk?
Kate L. Burbury, Michael Dickinson, David A. Westerman & H. Miles Prince
Pages: 3246-3247
Published online: 07 Jul 2015
CitationforPrevention of thromboembolism in myeloma: expanding the tool-box of assays to predict the risk? | Full Text | References | PDF (184.1 KB) | Supplemental
  • 246 Views
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Article Commentary
Time to revise the revised-International Prognostic Scoring System?
Courtney D. DiNardo & Farhad Ravandi
Pages: 3248-3249
Published online: 18 Jun 2015
CitationforTime to revise the revised-International Prognostic Scoring System? | Full Text | References | PDF (171.4 KB) | Supplemental
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Reviews

Ibrutinib, idelalisib and obinutuzumab for the treatment of patients with chronic lymphocytic leukemia: three new arrows aiming at the target
Fortunato Morabito, Massimo Gentile, John F. Seymour & Aaron Polliack
Pages: 3250-3256
Published online: 07 Jul 2015
AbstractforIbrutinib, idelalisib and obinutuzumab for the treatment of patients with chronic lymphocytic leukemia: three new arrows aiming at the target | Full Text | References | PDF (240.5 KB) | Supplemental
  • 1322 Views
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Inherited variation in immune response genes in follicular lymphoma and diffuse large B-cell lymphoma
Kaspar Rene Nielsen, Rudi Steffensen, Thure Mors Haunstrup, Julie Støve Bødker, Karen Dybkær, John Baech, Martin Bøgsted & Hans Erik Johnsen
Pages: 3257-3266
Published online: 07 Jul 2015
AbstractforInherited variation in immune response genes in follicular lymphoma and diffuse large B-cell lymphoma | Full Text | References | PDF (333.8 KB) | Supplemental
  • 356 Views
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Clinical Dilemmas

Managing patients with higher-risk myelodysplastic syndrome with stable disease on hypomethylating agents
Mikkael A. Sekeres
Pages: 3267-3269
Published online: 07 Jul 2015
AbstractforManaging patients with higher-risk myelodysplastic syndrome with stable disease on hypomethylating agents | Full Text | References | PDF (175.9 KB) | Supplemental
  • 465 Views
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Original Articles: Clinical

Hodgkin lymphoma incidence in ethnic enclaves in California
Sally L. Glaser, Ellen T. Chang, Christina A. Clarke, Theresa H. M. Keegan, Juan Yang & Scarlett Lin Gomez
Pages: 3270-3280
Published online: 18 Jun 2015
AbstractforHodgkin lymphoma incidence in ethnic enclaves in California | Full Text | References | PDF (299.8 KB) | Supplemental
  • 320 Views
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Rituximab with cyclophosphamide, vincristine, non-pegylated liposomal doxorubicin and prednisone as first-line treatment for splenic marginal zone lymphoma: a Fondazione Italiana Linfomi phase II study
Emilio Iannitto, Stefano Luminari, Claudio Tripodo, Salvatrice Mancuso, Marina Cesaretti, Luigi Marcheselli, Francesco Merli, Caterina Stelitano, Angelo Michele Carella, Alberto Fragasso, Elisa Montechiarello, Giuseppina Ricciuti, Alessandro Pulsoni, Marco Paulli, Vito Franco & Massimo Federico
Pages: 3281-3287
Published online: 18 Jul 2015
AbstractforRituximab with cyclophosphamide, vincristine, non-pegylated liposomal doxorubicin and prednisone as first-line treatment for splenic marginal zone lymphoma: a Fondazione Italiana Linfomi phase II study | Full Text | References | PDF (288.9 KB) | Supplemental
  • 545 Views
  • 19 CrossRef citations
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18F-Fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography in mucosa-associated lymphoid tissue lymphoma: variation in 18F-FDG avidity according to site involvement
Seol Hoon Park, Jong Jin Lee, Hye Ok Kim, Dong Yun Lee, Cheolwon Suh, Hwoon-Yong Jung, Kee Don Choi, Do Hoon Kim, Jooryung Huh & Jin-Sook Ryu
Pages: 3288-3294
Published online: 06 Nov 2015
Abstractfor18F-Fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography in mucosa-associated lymphoid tissue lymphoma: variation in 18F-FDG avidity according to site involvement | Full Text | References | PDF (669.8 KB) | Supplemental
  • 308 Views
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High-dose therapy and autologous stem cell transplantation for extra-nodal NK/T lymphoma in patients from the Western hemisphere: a study from the European Society for Blood and Marrow Transplantation
Christopher P. Fox, Ariane Boumendil, Norbert Schmitz, Herve Finel, Jian J. Luan, Gülsan Sucak, Didier Blaise, Jürgen Finke, Karl-Heinz Pflüger, Hendrik Veelken, Norbert -Claude Gorin, Xavier Poiré, Arnold Ganser, Peter Dreger & Anna Sureda
Pages: 3295-3300
Published online: 26 Aug 2015
AbstractforHigh-dose therapy and autologous stem cell transplantation for extra-nodal NK/T lymphoma in patients from the Western hemisphere: a study from the European Society for Blood and Marrow Transplantation | Full Text | References | PDF (234.6 KB) | Supplemental
  • 567 Views
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Histopathological analysis of B-cell non-Hodgkin lymphomas without light chain restriction by using flow cytometry
Akihiro Ohmoto, Akiko Miyagi Maeshima, Hirokazu Taniguchi, Kensaku Tanioka, Shinichi Makita, Hideaki Kitahara, Suguru Fukuhara, Wataru Munakata, Tatsuya Suzuki, Dai Maruyama, Yukio Kobayashi & Kensei Tobinai
Pages: 3301-3305
Published online: 12 May 2015
AbstractforHistopathological analysis of B-cell non-Hodgkin lymphomas without light chain restriction by using flow cytometry | Full Text | References | PDF (418.6 KB) | Supplemental
  • 326 Views
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Chronic fatigue is prevalent and associated with hormonal dysfunction in long-term non-Hodgkin lymphoma survivors treated with radiotherapy to the head and neck region
Mette Seland, Harald Holte, Trine Bjøro, Thomas Schreiner, Jens Bollerslev, Jon Håvard Loge, Sophie D. Fosså & Cecilie E. Kiserud
Pages: 3306-3314
Published online: 18 May 2015
AbstractforChronic fatigue is prevalent and associated with hormonal dysfunction in long-term non-Hodgkin lymphoma survivors treated with radiotherapy to the head and neck region | Full Text | References | PDF (260.3 KB) | Supplemental
  • 442 Views
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Joint occurrence of Merkel cell carcinoma and non-Hodgkin lymphomas in four Nordic countries
Virve Koljonen, Matti Rantanen, Helka Sahi, Lene Mellemkjær, Bo Terning Hansen, Tianhui Chen, Kari Hemminki & Eero Pukkala
Pages: 3315-3319
Published online: 26 May 2015
AbstractforJoint occurrence of Merkel cell carcinoma and non-Hodgkin lymphomas in four Nordic countries | Full Text | References | PDF (207.8 KB) | Supplemental
  • 177 Views
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Phase 1/2 study of cyclin-dependent kinase (CDK)4/6 inhibitor palbociclib (PD-0332991) with bortezomib and dexamethasone in relapsed/refractory multiple myeloma
Ruben Niesvizky, Ashraf Z. Badros, Luciano J. Costa, Scott A. Ely, Seema B. Singhal, Edward A. Stadtmauer, Nisreen A. Haideri, Abdulraheem Yacoub, Georg Hess, Suzanne Lentzsch, Ivan Spicka, Asher A. Chanan-Khan, Marc S. Raab, Stefano Tarantolo, Ravi Vij, Jeffrey A. Zonder, Xiangao Huang, David Jayabalan, Maurizio Di Liberto, Xin Huang, Yuqiu Jiang, Sindy T. Kim, Sophia Randolph & Selina Chen-Kiang
Pages: 3320-3328
Published online: 15 May 2015
AbstractforPhase 1/2 study of cyclin-dependent kinase (CDK)4/6 inhibitor palbociclib (PD-0332991) with bortezomib and dexamethasone in relapsed/refractory multiple myeloma | Full Text | References | PDF (299.7 KB) | Supplemental
  • 1619 Views
  • 50 CrossRef citations
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Expression patterns of CD200 and CD148 in leukemic B-cell chronic lymphoproliferative disorders and their potential value in differential diagnosis
Lei Fan, Yi Miao, Yu-Jie Wu, Yan Wang, Rui Guo, Li Wang, An-Li Shen, Yao-Yu Chen, Wei Xu & Jian-Yong Li
Pages: 3329-3335
Published online: 19 Jun 2015
AbstractforExpression patterns of CD200 and CD148 in leukemic B-cell chronic lymphoproliferative disorders and their potential value in differential diagnosis | Full Text | References | PDF (292 KB) | Supplemental
  • 699 Views
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Obatoclax in combination with fludarabine and rituximab is well-tolerated and shows promising clinical activity in relapsed chronic lymphocytic leukemia
Jennifer R. Brown, Bethany Tesar, Lijian Yu, Lillian Werner, Naoko Takebe, Evgeny Mikler, Hazel M. Reynolds, Christina Thompson, David C. Fisher, Donna Neuberg & A. S. Freedman
Pages: 3336-3342
Published online: 18 Jun 2015
AbstractforObatoclax in combination with fludarabine and rituximab is well-tolerated and shows promising clinical activity in relapsed chronic lymphocytic leukemia | Full Text | References | PDF (288.9 KB) | Supplemental
  • 293 Views
  • 25 CrossRef citations
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Chronic myeloid leukemia with e14a3 BCR-ABL transcript: analysis of characteristics and prognostic significance
Gui Xiaomin, Zhang Yong, Pan Jinlan, Qiu Huiying, Cen Jiannong, Xue Yongquan, Chen Suning, Shen Hongjie, Yao Li, Zhang Jun, Wu Yafang & Chen Yan
Pages: 3343-3347
Published online: 19 Jun 2015
AbstractforChronic myeloid leukemia with e14a3 BCR-ABL transcript: analysis of characteristics and prognostic significance | Full Text | References | PDF (232.2 KB) | Supplemental
  • 405 Views
  • 12 CrossRef citations
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High incidence of intact or fragmented immunoglobulin in urine of patients with multiple myeloma
Maria Kraj, Barbara Kruk, Ewa Lech-Marańda, Krzysztof Warzocha & Monika Prochorec-Sobieszek
Pages: 3348-3356
Published online: 13 May 2015
AbstractforHigh incidence of intact or fragmented immunoglobulin in urine of patients with multiple myeloma | Full Text | References | PDF (272.3 KB) | Supplemental
  • 293 Views
  • 4 CrossRef citations
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Clinical and prognostic differences among patients with light chain deposition disease, myeloma cast nephropathy and both
Ladan Zand, Samih H. Nasr, Morie A Gertz, Angela Dispenzieri, Martha Q. Lacy, Francis K. Buadi, Shaji Kumar, Robert A. Kyle, Fernando C. Fervenza, Sanjeev Sethi, David Dingli, S. Vincent Rajkumar, Prashant Kapoor, Arleigh McCurdy & Nelson Leung
Pages: 3357-3364
Published online: 12 May 2015
AbstractforClinical and prognostic differences among patients with light chain deposition disease, myeloma cast nephropathy and both | Full Text | References | PDF (461.2 KB) | Supplemental
  • 857 Views
  • 32 CrossRef citations
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Control of relapsed or refractory acute myeloid leukemia by clofarabine in preparation for allogeneic stem cell transplant
Claudia Loeffler, Markus Kapp, Goetz-Ulrich Grigoleit, Stephan Mielke, Jürgen Loeffler, Peter U. Heuschmann, Uwe Malzahn, Elke Hupp, Hermann Einsele & Gernot Stuhler
Pages: 3365-3369
Published online: 19 Jun 2015
AbstractforControl of relapsed or refractory acute myeloid leukemia by clofarabine in preparation for allogeneic stem cell transplant | Full Text | References | PDF (202.2 KB) | Supplemental
  • 556 Views
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Etiology, clinical course and outcome of healthcare-associated bloodstream infections in patients with hematological malignancies: a retrospective study of 350 patients in a Finnish tertiary care hospital
Emilia Åttman, Janne Aittoniemi, Marjatta Sinisalo, Risto Vuento, Outi Lyytikäinen, Tommi Kärki, Jaana Syrjänen & Reetta Huttunen
Pages: 3370-3377
Published online: 26 Mar 2015
AbstractforEtiology, clinical course and outcome of healthcare-associated bloodstream infections in patients with hematological malignancies: a retrospective study of 350 patients in a Finnish tertiary care hospital | Full Text | References | PDF (314 KB) | Supplemental
  • 311 Views
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Original Articles: Research

Article
Chronic lymphocytic leukemia/small lymphocytic lymphoma: another neoplasm related to the B-cell follicle?
Bevan Tandon, Steven H. Swerdlow, Robert P. Hasserjian, Urvashi Surti & Sarah E. Gibson
Pages: 3378-3386
Published online: 26 May 2015
AbstractforChronic lymphocytic leukemia/small lymphocytic lymphoma: another neoplasm related to the B-cell follicle? | Full Text | References | PDF (1.1 MB) | Supplemental
  • 542 Views
  • 7 CrossRef citations
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Article
Transplant of ex vivo incubated bone marrow with rIL -7 for the enhancement of immuno-hematopoietic reconstitution
Ali Abdul-Hai, Aryeh Ben Yehuda, Shimon Slavin & Reuven Or
Pages: 3387-3392
Published online: 20 Nov 2015
AbstractforTransplant of ex vivo incubated bone marrow with rIL -7 for the enhancement of immuno-hematopoietic reconstitution | Full Text | References | PDF (221.5 KB) | Supplemental
  • 138 Views
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Article
Temsirolimus inhibits cell growth in combination with inhibitors of the B-cell receptor pathway
Anna-Katharina Zoellner, Stephan Bayerl, Grit Hutter, Yvonne Zimmermann, Wolfgang Hiddemann & Martin Dreyling
Pages: 3393-3400
Published online: 03 Aug 2015
AbstractforTemsirolimus inhibits cell growth in combination with inhibitors of the B-cell receptor pathway | Full Text | References | PDF (430.5 KB) | Supplemental
  • 313 Views
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Article
NPM-RAR binding to TRADD selectively inhibits caspase activation, while allowing activation of NFκB and JNK
Anuja Chattopadhyay, Irina Abecassis & Robert L. Redner
Pages: 3401-3406
Published online: 19 Mar 2015
AbstractforNPM-RAR binding to TRADD selectively inhibits caspase activation, while allowing activation of NFκB and JNK | Full Text | References | PDF (365.8 KB) | Supplemental
  • 159 Views
  • 5 CrossRef citations
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Article
The MEK1/2 inhibitor, MEKi-1, induces cell death in chronic lymphocytic leukemia cells under conditions that mimic the tumor microenvironment and is synergistic with fludarabine
Kyle Crassini, William S. Stevenson, Stephen P. Mulligan & O. Giles Best
Pages: 3407-3417
Published online: 26 Aug 2015
AbstractforThe MEK1/2 inhibitor, MEKi-1, induces cell death in chronic lymphocytic leukemia cells under conditions that mimic the tumor microenvironment and is synergistic with fludarabine | Full Text | References | PDF (589.5 KB) | Supplemental
  • 404 Views
  • 13 CrossRef citations
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Article
Thromboelastography, thrombin generation test and thrombodynamics reveal hypercoagulability in patients with multiple myeloma
Marina A. Gracheva, Evdokiya S. Urnova, Elena I. Sinauridze, Ivan D. Tarandovskiy, Elena B. Orel, Alexander V. Poletaev, Larisa P. Mendeleeva, Fazoil I. Ataullakhanov & Anna N. Balandina
Pages: 3418-3425
Published online: 18 Jun 2015
AbstractforThromboelastography, thrombin generation test and thrombodynamics reveal hypercoagulability in patients with multiple myeloma | Full Text | References | PDF (316.7 KB) | Supplemental
  • 563 Views
  • 44 CrossRef citations
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Article
Analysis of class I and II histone deacetylase gene expression in human leukemia
Hui Yang, Sirisha Maddipoti, Andres Quesada, Zachary Bohannan, Monica Cabrero Calvo, Simona Colla, Yue Wei, Marcos Estecio, William Wierda, Carlos Bueso-Ramos & Guillermo Garcia-Manero
Pages: 3426-3433
Published online: 26 May 2015
AbstractforAnalysis of class I and II histone deacetylase gene expression in human leukemia | Full Text | References | PDF (410.6 KB) | Supplemental
  • 415 Views
  • 17 CrossRef citations
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Letters to the Editor

Letter
Point mutations in TP53 but not in p15Ink4b and p16Ink4a genes represent poor prognosis factors in acute adult T cell leukemia/lymphoma
Marcelo Magalhaes, Pedro D. Oliveira, Achiléa L. Bittencourt & Lourdes Farre
Pages: 3434-3436
Published online: 09 Jan 2015
First Page PreviewforPoint mutations in TP53 but not in p15Ink4b and p16Ink4a genes represent poor prognosis factors in acute adult T cell leukemia/lymphoma | Full Text | References | PDF (198.6 KB) | Supplemental
  • 178 Views
  • 2 CrossRef citations
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Letter
The Revised International Prognostic Scoring System (IPSS-R) is not predictive of survival in patients with secondary myelodysplastic syndromes
Aziz Nazha, David P. Seastone, Michael Keng, Sean Hobson, Matt Kalaycio, Jaroslaw P. Maciejewski & Mikkael A. Sekeres
Pages: 3437-3439
Published online: 19 Jun 2015
First Page PreviewforThe Revised International Prognostic Scoring System (IPSS-R) is not predictive of survival in patients with secondary myelodysplastic syndromes | Full Text | References | PDF (193.8 KB) | Supplemental
  • 327 Views
  • 16 CrossRef citations
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Letter
Corneal sub-basal neural damage pattern in multiple myeloma patients treated with bortezomib: an in vivo confocal study
Federica Cocito, Gabriella Ricciardelli, Silvia Mangiacavalli, Alessandra Pompa, Lara Pochintesta, Virginia Ferretti, Roberto Ceccuzzi, Mario Cazzola, Paolo Emilio Bianchi & Alessandro Corso
Pages: 3440-3441
Published online: 18 Jun 2015
CitationforCorneal sub-basal neural damage pattern in multiple myeloma patients treated with bortezomib: an in vivo confocal study | Full Text | References | PDF (198.6 KB) | Supplemental
  • 228 Views
  • 2 CrossRef citations
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Letter
Candida glabrata fungaemia at an Australian cancer centre: epidemiology, risk factors and therapy
Jason A. Trubiano, Vivian K. Y. Leung, Leon J. Worth, Benjamin W. Teh, Karin A. Thursky & Monica A. Slavin
Pages: 3442-3444
Published online: 20 Nov 2015
First Page PreviewforCandida glabrata fungaemia at an Australian cancer centre: epidemiology, risk factors and therapy | Full Text | References | PDF (147.4 KB) | Supplemental
  • 139 Views
  • 5 CrossRef citations
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Letter
Acute myeloid leukemia cells exhibit selective down-regulation of DNMT3A isoform 2
Helen J. S. Stewart, Ella Shalit, Loryn Halliday, Dominic Morey & Timothy J. Chevassut
Pages: 3445-3448
Published online: 19 Jun 2015
First Page PreviewforAcute myeloid leukemia cells exhibit selective down-regulation of DNMT3A isoform 2 | Full Text | References | PDF (234.3 KB) | Supplemental
  • 285 Views
  • 2 CrossRef citations
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Letter
A new NPM1 gene mutation
Francisco José Illana, Antonio Manrique, Erika Coria-Ramírez & Eduardo Anguita
Pages: 3449-3451
Published online: 18 Jun 2015
First Page PreviewforA new NPM1 gene mutation | Full Text | References | PDF (219.8 KB) | Supplemental
  • 195 Views
  • 0 CrossRef citations
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Letter
Bleeding diathesis associated with acquired von Willebrand Syndrome in three patients with chronic lymphocytic leukemia
Mona Lisa Alattar, Maria Ciccone, Mahmoud R. Gaballa, Candida Vitale, Xavier C. Badoux, George Manoukian, Michael J. Keating, Michael H. Kroll & Alessandra Ferrajoli
Pages: 3452-3454
Published online: 26 May 2015
First Page PreviewforBleeding diathesis associated with acquired von Willebrand Syndrome in three patients with chronic lymphocytic leukemia | Full Text | References | PDF (189.6 KB) | Supplemental
  • 336 Views
  • 8 CrossRef citations
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Correspondence

Rapid Communication
The role of T-cell phenotype and T-cell receptor rearrangement in the diagnosis of T-cell malignancies: author's reply
Anna Flammiger & Mascha Binder
Page: 3455
Published online: 19 Jun 2015
CitationforThe role of T-cell phenotype and T-cell receptor rearrangement in the diagnosis of T-cell malignancies: author's reply | Full Text | References | PDF (157.7 KB) | Supplemental
  • 91 Views
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Rapid Communication
Understanding sarcopenia as a predictor of response to autologous hematopoietic stem cell transplant
Umit Cintosun & Battal Altun
Page: 3456
Published online: 18 Jul 2015
CitationforUnderstanding sarcopenia as a predictor of response to autologous hematopoietic stem cell transplant | Full Text | References | PDF (145.7 KB) | Supplemental
  • 179 Views
  • 2 CrossRef citations
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