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Letters to the Editor

Decreased normal NK-cells is a characteristic of T-cell large granular lymphocytic leukemia and is strongly associated with cytopenia

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Pages 1230-1233 | Received 03 Jul 2015, Accepted 04 Aug 2015, Published online: 21 Dec 2015

References

  • Lamy T, Loughran TP, Jr. How I treat LGL leukemia. Blood. 2011;117:2764–2774.
  • Goronzy JJ, Weyand CM. T cell development and receptor diversity during aging. Curr Opin Immunol. 2005;17:468–475.
  • Khan N, Shariff N, Cobbold M, et al. Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals. J Immunol. 2002;169:1984–1992.
  • Messaoudi I, Lemaoult J, Guevara-Patino JA, et al. Age-related CD8 T cell clonal expansions constrict CD8 T cell repertoire and have the potential to impair immune defense. J Exp Med. 2004;200:1347–1358.
  • Strioga M, Pasukoniene V, Characiejus D. CD8 + CD28- and CD8 + CD57 + T cells and their role in health and disease. Immunology. 2011;134:17–32.
  • Morice WG, Kurtin PJ, Leibson PJ, et al. Demonstration of aberrant T-cell and natural killer-cell antigen expression in all cases of granular lymphocytic leukaemia. Br J Haematology. 2003;120:1026–1036.
  • Hasenclever D, Diehl V. A prognostic score for advanced Hodgkin’s disease. International Prognostic Factors Project on Advanced Hodgkin’s Disease. N Engl J Med. 1998;339:1506–1514.
  • Plonquet A, Haioun C, Jais JP, et al. Peripheral blood natural killer cell count is associated with clinical outcome in patients with aaIPI 2-3 diffuse large B-cell lymphoma. Ann Oncol. 2007;18:1209–1215.
  • Kim JK, Chung JS, Shin HJ, et al. Influence of NK cell count on the survival of patients with diffuse large B-cell lymphoma treated with R-CHOP. Blood Res. 2014;49:162–169.
  • Imai K, Matsuyama S, Miyake S, et al. Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population. Lancet. 2000;356:1795–1799.
  • Mandal A, Viswanathan C. Natural killer cells: in health and disease. Hematol Oncol Stem Cell Therapy. 2015;8:47–55.
  • Chan CJ, Smyth MJ, Martinet L. Molecular mechanisms of natural killer cell activation in response to cellular stress. Cell Death Diff. 2014;21:5–14.
  • Morice WG, Neff J, Kwan J. Gaining insights into chronic natural killer cell leukemias through extensive characterization of an individual case. Mayo Clinic Proc. 2011;86:1247–1248.
  • Mishra A, Liu S, Sams GH, et al. Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation. Cancer Cell. 2012;22:645–655.
  • Kothapalli R, Nyland SB, Kusmartseva I, et al. Constitutive production of proinflammatory cytokines RANTES, MIP-1beta and IL-18 characterizes LGL leukemia. Intl J Oncol. 2005;26:529–535.

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