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Leukemia & Lymphoma Volume 13, 1994 - Issue 5-6
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Original Article

An Aggressive High Dose Cyclophosphamide and Prednisone Regimen for Advanced Multiple Myeloma

R. E. Lenhard Johns Hopkins Oncology Center, Baltimore, Maryland
,
M. J. Daniels Dana-Farber Cancer Institute, Boston, Massachusetts
,
M. M. Oken Virginia Piper Cancer Institute, Minneapolis, Minnesota; Northwestern University Medical Center, Chicago, Illinois
,
J. H. Glick University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania
,
D. S. Ettinger Johns Hopkins Oncology Center, Baltimore, Maryland
,
L. Kalish Johns Hopkins Oncology Center, Baltimore, Maryland
&
M. J. O'connell Mayo Clinic, Rochester, Minnesota, USA
 show all
Pages 485-489 | Received 26 Jul 1993, Published online: 01 Jul 2009

References

  • Alexanian R., Haut A., Khan A. U., Lane M., McKelvey E. M., Milgore P. J., Stuckey W. J., Wilson H. E. Treatment for multiple myeloma: combination chemotherapy with different melphalan dose regimens. JAMA 1969; 208: 1680–1685
  • Costa G., Engle R. L., Schilling A., Carbone P., Kochwa S., Nachman R. L., Glidewell O. Melphalan and prednisone: an effective combination for the treatment of multiple myeloma. Am. J. Med. 1973; 54: 589–599
  • Lenhard R. E., Oken M. M., Barnes J. M., Humphrey R. L., Glick J. H., Silverstein M. N. High dose cyclophosphamide: an effective treatment for advanced refractory multiple myeloma. Cancer 1984; 53: 1456–1460
  • Mullins G. M., Anderson P. N., Santos G. W. High dose cyclophosphamide therapy in solid tumors: therapeutic, toxic, and immunosuppressive effects. Cancer 1975; 36: 1950–1958
  • Bergsagel D. E., Cowan D. H., Hasselbach R. Plasma cell myeloma: response of melphalan-resistant patients to high-dose intermittent cyclophosphamide and prednisone. C.M.A.J. 1972; 107: 851–855
  • Alexanian R., Yap B. S., Bodey G. P. Prednisone pulse therapy for refractory myeloma. Blood 1983; 62: 572–577
  • Salmon S. E., Shadduck R. K., Schilling A. Intermittent high dose prednisone therapy for multiple myeloma. Cancer Chemother. Rep. 1967; 51: 179–187
  • McLntyre O. R., Pajak T. F., Kyle R. A., Cornwell G. G., Louis L. Response rate and survival in myeloma patients receiving prednisone alone. Med. Pediatr. Oncol. 1985; 13: 239–243
  • Alexanian R., Yap B. S., Bodey G. P. Prednisone pulse therapy for refractory myeloma. Blood 1983; 62: 572–577
  • Salmon S. E., Shadduck R. K., Schilling A. Intermittent high-dose prednisone (NSC-10023) therapy for multiple myeloma. Cancer Chemother. Rep. 1967; 51: 179–187
  • Lenhard R. E., Prentice R. L., Owens A. H., Bakemeier R., Horton J. H., Shnider B. I., Stolbach L., Berard C. W., Carbone P. P. Combination chemotherapy of the malignant lymphomas: a controlled clinical trial. Cancer 1976; 38: 1052–1059
  • Oken M. M., Lenhard R. E., Tsiatis A. A., Glick J. H., Silverstein M. N. The contribution of prednisone to the effectiveness of hexamethylmelamine in multiple myeloma. Cancer, Treat. Rep. 1987; 71: 807–811
  • Karp J. E., Burke P. J., Humphrey R. L. Induction of serum stimulation and plasma cell proliferation during chemotherapy of multiple myeloma. Blood 1977; 49: 925–934
  • Frondoza C. G., Trivedi S. M., Humphrey R. L. Development and characterization of a cyclophosphamide-re-sistant mouse plasmacytoma cell line. Cancer Treat. Rep. 1982; 66: 1535–1544
  • Lenhard R. E., Tsiatis A. A., Oken M. M., Humphrey R. L., Glick J. H. Sime sequential high dose cyclophosphamide and vincristine treatment of multiple myeloma. Proc. ACSO 1985; 4: 217
  • Mehta C. R., Patel N. R. A network algorithm for performing Fisher's exact test in rxc contingency tables. J. Am. Statist. Assoc 1983; 78: 427–434
  • Kaplan E. L., Meier P. Nonparametric estimation from incomplete observations. J. Am. Statist. Assoc 1958; 53: 457–481
  • Peto R., Peto J. Asymptotically efficient rank invariant test procedures (with discussion). J. R. Statist. Soc A 1972; 136: 185–206
  • Cox D. R. Regression models and life tables (with discussion). J. R. Statist. Soc. B 1972; 34: 187–220
  • Oken M. M., Creech R. H., Tormey D. C., Horton J., Davis T. E., McFadden E., Carbone P. P. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am. J. Clin. Oncol. 1982; 5: 649–665

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