Advanced search
Publication Cover
Leukemia & Lymphoma Volume 19, 1995 - Issue 1-2
Submit an article Journal homepage
143
Views
43
CrossRef citations to date
0
Altmetric
Original Article

A Controlled Trial of Tranexamic Acid Therapy for the Reduction of Bleeding During Treatment of Acute Myeloid Leukemia

O. Shpilberg The Institute of Hematology, Department of Hematology, Hadassah University Hospital, Jerusalem
,
R. Blumenthal The Institute of Hematology, Department of Hematology, Hadassah University Hospital, Jerusalem
,
O. Sofer The Institute of Hematology, Department of Hematology, Hadassah University Hospital, Jerusalem
,
Y. Katz The Institute of Hematology, Department of Hematology, Hadassah University Hospital, Jerusalem
,
A. Chetrit The Institute of Hematology, Department of Clinical Epidemiology, The Chaim Sheba Medical Center, Tel-Hashomer and Sackler School of Medicine. Tel-Aviv University, Jerusalem
,
B. Ramot The Institute of Hematology, Department of Hematology, Hadassah University Hospital, Jerusalem
,
A. Eldor The Institute of Hematology, Department of Hematology, Hadassah University Hospital, Jerusalem
&
I. Ben-Bassat
 show all
Pages 141-144 | Received 25 Nov 1994, Published online: 01 Jul 2009

References

  • Cattan A., Schwarzenber L., Schnieder M, et al. Essai de Essai de traitement par Pacide epsilon-amino-caproique de patients attains de syndromes hemorragiques, en particulier de syndromes lies a une thrombocytopenie. Presse Medicale 1963; 71: 2037–2038
  • Gardner F.H., Helmer R.E.I., II. Aminocaproic acid. Use in control of hemorrhage in patients with amegakaryocytic thrombocytopenia. J. Am. Med. Assn. 1980; 243: 35–37
  • Bartholomew J.R., Salgia R., Bell W.R. Control of bleeding in patients with immune and nonimmune thrombocytopenia with aminocaproic acid. Arch. Int. Med. 1989; 149: 1959–1961
  • Gallardo R.L., Gardner F.H. Antifibrinolytic therapy for bleeding control during remission induction for acute leukemia. Blond 1983; 62: 202a, suppl. I
  • Garewal H.S., Durie B.G.M. Antifibrinolytic therapy with aminocaproic acid for the control of bleeding in thrombocytopenic patients. Scandinavian. J. Haematol. 1985; 35: 497–500
  • Gallardo R.L., Gardner F.H. Aminocaproic acid in thrombocytopenic patients. Texas Medicine 1985; 81: 30–32
  • Ben-Bassat I., Douer D., Ramot B. Tranexamic acid therapy in acute myeloid leukemia: Possible reduction of platelet tansfusions. Eur. J. Haematol. 1990; 45: 86–89
  • National Institutes of Health., Consensus development conference on platelet transfusion therapy. J. Am. Med. Assn. 1987; 257: 1777–1780
  • Gmur J., Burger J., Schanz U., Fehr J., Schaffner A. Safety of stringent prophylactic platelet transfusion policy for patients with acute leukemia. Lancet. 1991; 338: 1223–1236
  • Beutler E. Platelet transfusions: The 20,000/μL trigger. Blood 1993; 81: 1411–1413
  • Stachurska J., Latallo Z., Kopec M. Inhibition of platelet aggregation by dialysable fibrinogen degradation products (FDP). Thrombosis et Diathesis Haemorrhogica 1970; 23: 91–97
  • Adelman B., Michelson A.D., Loscalzo J., Greenberg J., Handin R.I. Plasmin effect on platelet glycoprotein Ib-von Willebrand factor interactions. Blood 1985; 65: 32–40
  • Schafer A.I., Adelman B. Plasmin inhibition of platelet function and of arachidonic acid metabolism. J. Clin, Invest. 1985; 75: 456–461
  • Speiser W., Pabinger-Fasching I., Kyrle P.A., Kapiotis S., Kottas-Heldenberg A., Bettelheim und P., Lechner K. Hemostatic and fibrinolytic parameters in patients with activation of blood coagulation, fibrinolysis and unspecific proteolysis. Blut 1990; 61: 298–302
  • Tallman M.S., Kwaan H.C. Reassessing the hemostatic disorder associated with acute promyelocytic leukemia. Blood. 1992; 79: 543–553
  • Dombret H., Scrobohaci M.L., Ghorra P., Zini J-M., Daniel M.T., Castaigne S., Degos L. Coagulation disorders associated with acute promyelocytic leukemia: Corrective effect of all-trans retinoic acid treatment. Leukemia 1993; 7: 2–9
  • Kario K., Matsuo T., Kodama K., Matsuo M., Yamamoto K., Kobayashi H. Imbalance between thrombin and plasmin activity in disseminated intravascular coagulation. Assessment by the thrombin-antithrombin-III complex/plasmin-alpha-2-antiplasmin complex ratio. Hemostasis 1992; 22: 178–186

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.