Differentiation Inhibitory Factor Nm23 as a Prognostic Factor for Acute Myeloid Leukemia

References

• Okabe-Kado J., Kasukabe T., Honma Y., Hayashi M., Henzel W. J., Hozumi M. Identity of a differentiation inhibiting factor for mouse myeloid leukemia cells with NM23/nucleoside diphosphate kinase. Biochem. Biophys. Res. Commun. 1992; 182: 987–994
   PubMed Web of Science ®Google Scholar
• Okabe-Kado J., Kasukabe T., Hozumi M., Honma Y., Kimura N., Baba H., Urano T., Shiku H. A new function of Nm23/NDP kinase as a differentiation inhibitory factor, which does not require its kinase activity. FEBS Lett. 1995; 363: 311–315
   PubMed Web of Science ®Google Scholar
• Okabe-Kado J., Kasukabe T., Baba H., Urano T., Shiku H., Honma Y. Inhibitory action of jim23 proteins on induction of erythroid differentiation of human leukemia cells. Biochim. Biophys. Acta. 1995; 1267: 101–106
   PubMed Web of Science ®Google Scholar
• Steeg P. S., Bevilacqua G., Kopper L., Thorgeirsson U. P., Talmadge J. E., Liotta L. A., Sobel M. E. Evidence for a novel gene associated with low tumor metastatic potential. J. Natll. Cancer Inst. 1988; 80: 200–204
   PubMed Web of Science ®Google Scholar
• Baba H., Urano T., Okada K., Furukawa K., Nakayama E., Tanaka H., Iwasaki K., Shiku H. Two isotypes of murine nm23/nucleoside diphosphate kinase, nm23-M1 and nm23-M2, are involved in metastatic suppression of a murine melanoma line. Cancer Res. 1995; 55: 1977–1981
   PubMed Web of Science ®Google Scholar
• Fukuda M., Ishii A., Yasutomo Y., Shimada N., Ishikawa N., Hanai N., Nagara N., Irimura T., Nicolson G., Kimura N. Metastatic potential of rat mammary adenocarcinoma cells associated with decreased expression of nucleoside diphosphate kinase/nm23: reduction by transfec-tion of NDP kinase a isoform, an nm23-H2 gene homolog. Int. J. Cancer 1996; 65: 531–537
   PubMed Web of Science ®Google Scholar
• Leone A., Flatow U., King C. R., Sandeen M. A., Margulies I. M. K., Liotta L. A., Steeg P. S. Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells. Cell 1991; 65: 25–35
   PubMed Web of Science ®Google Scholar
• Leone A., Flatow U., Vanhoutte K., Steeg P. S. Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization, and enzymatic activity. Oncogene 1993; 8: 2325–2333
   PubMed Web of Science ®Google Scholar
• Parhar R. S., Shi Y., Zou M, Farid N. R., Ernst P., Al-Sedairy S. Effects of cytokine mediated modulation of Nm23 expression on the invasion and metastatic behavior of B16F10 melanoma cells. Int. J. Cancer 1995; 60: 204–210
   PubMed Web of Science ®Google Scholar
• Dearolf C., Hersperger E., Shearn A. Developmental consequences of awdb3, a cell autonomous lethal mutation of Drosophila induced by hybrid dysgenesis. Developmental Biology 1988; 129: 159–168
   PubMed Web of Science ®Google Scholar
• Dearolf C., Tripoulas N., Biggs J., Shearn A. Molecular consequences of awdb3, a cell autonomous lethal mutation of Drosophila induced by hybrid dysgenesis. Developmental Biology 1988; 129: 169–178
   PubMed Web of Science ®Google Scholar
• Stahl J. A., Leone A., Rosengard A. M., Porter L., King C. R., Steeg P S. Identification of a second human nm23, gene, nm23-H2. Cancer Res. 1991; 51: 445–449
   PubMed Web of Science ®Google Scholar
• Gilles A. M., Presecan E., Vonica A., Lascu I. Nucleoside diphosphate kinase from human erythrocytes. J. Biol. Chem. 1991; 266: 8784–8789
   PubMed Web of Science ®Google Scholar
• Chandrasekharappa S. C., Gross L. A., King S. E., Collins F. S. The human NME2, gene lies within 18kb of NMEfm, chromosome 17. Genes Chromosomes Cancer 1993; 6: 245–248
   PubMed Web of Science ®Google Scholar
• Backer J. M., Mendra C. E., Kovesdi I., Fairhurst J. L., O'Hara B., Eddy R. L., Shows T. B., Methew S., Murty V. V.V.S., Chaganti R. S.K. Chromosomal localization and nucleoside diphosphate kinase activity of human metastasis-suppressor genes NM23–1, and NM23–2. Oncogene 1993; 8: 497–502
   PubMed Web of Science ®Google Scholar
• Okada K., Urano T., Goi T., Baba H., Yamaguchi A., Furukawa K., Shiku H. Isolation of human nm23, genomes and analysis of loss of heterozygosity in primary colorectal carcinomas using a specific genomic probe. Cancer Res. 1994; 54: 3979–3982
   PubMed Web of Science ®Google Scholar
• De La Rosa A., Williams R. L., Steeg P. S. Nm2J/nucleoside diphosphate kinase: toward a structural and biochemical understanding of its biological functions. BioEssays 1995; 17: 53–62
   PubMed Web of Science ®Google Scholar
• Lacombe M.-L., Wallet V., Troll H., Veron M. Functional cloning of a nucleoside diphosphate kinase from Dictyostelium discoideum. J. Biol. Chem 1990; 265: 10012–10018
   PubMed Web of Science ®Google Scholar
• Biggs J., Hersperger E., Steeg P. S., Liotta L. A., Shearn A. A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase. Cell 1990; 63: 933–940
   PubMed Web of Science ®Google Scholar
• Venturelli D., Martinez R., Melotti P., Casella I., Peschle C, Cucco C, Spampinato G., Darzynkiewicz Z., Calabretta B. Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells. Proc. Natl. Acad. Sci. USA 1995; 92: 7435–7439
   PubMed Web of Science ®Google Scholar
• Martinez R., Venturelli D., Perrotti D., Veronese M. L., Kastury K., Druck T., Huebner K., Calabretta B. Gene structure, promoter activity, and chromosomal location of the DR-nm23 gene, a related member of the nm23 gene family. Cancer Res. 1997; 57: 1180–1187
   PubMed Web of Science ®Google Scholar
• Milon L., Rousseau-Merck M.-F., Munier A., Erent M., Lascu I., Capeau J., Lacombe M.-L. nm23-H4, a new member of the family of human nm23/nucleoside diphosphate kinase genes localised on chomosome 16p13. Hum. Genet. 1997; 99: 550–557
   PubMed Web of Science ®Google Scholar
• Macdonald N. I., Delarosa A., Benedict M. A., Freije I. M.P., Krutsh H., Steeg P. S. A serine phosphorylation of nm23, and not its nucleoside diphosphate kinase activity, correlates with suppression o tumor metastatic potential. J. Biol. Chem. 1993; 268: 25780–25789
   PubMed Web of Science ®Google Scholar
• Marcu K. B., Bossone S. A., Patel A. J. Myc function and regulation. Anna Rev Biochem 1992; 61: 809–860
   PubMed Web of Science ®Google Scholar
• Postel E. H., Borberich S., Flint S. J., Ferrone C. A. Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis. Science 1993; 261: 478–480
   PubMed Web of Science ®Google Scholar
• Cole M. D. The myc oncogene: its role in transformation and differentiation. Annu Rev Genett 1986; 20: 361–384
   PubMed Web of Science ®Google Scholar
• Spencer C A, Groudine M. Control of c-myc regulation in normal and neoplastic cells. Adv. Cancer Res. 1991; 56: 1–48
   PubMed Web of Science ®Google Scholar
• Keim D., Hailat N., Melhem R., Zhu X. X., Lascu I., Veron M., Strahlen J., Hanash S. M. Proliferation-related expression of p19/nm23 nucleoside diphosphate kinase. J. Clin. Invest. 1992; 89: 919–924
   PubMed Web of Science ®Google Scholar
• Yamashiro S., Urano T., Shiku H., Furukawa K. Alteration of nm23 gene expression during the induced differentiation of human leukemia cell lines. Oncogene 1994; 9: 2461–2468
   PubMed Web of Science ®Google Scholar
• Yokoyama A., Okabe-Kado J., Sakashita A., Maseki N., Kaneko Y., Hino K., Tomoyasu S., Tsuruoka N., Kasuk-Abe T., Honma Y. Differentiation inhibitory factor nm23 as a new prognostic factor in acute monocytic leukemia. Blood 1996; 88: 3555–3561
   PubMed Web of Science ®Google Scholar
• Yokoyama A., Okabe-Kado J., Wakimoto N., Kobayashi H., Sakashita A., Maseki N., Nakamaki T., Hino K., Tomoyasu S., Tsuruoka N., Motoyoshi K., Nagata N., Honma Y. Evaluation by multivariate analysis of the differentiation inhibitory factor nm23 as a prognostic factor in acute myelogenous leukemia and application to other hematological malignancies. Blood 1998, in press
   Web of Science ®Google Scholar
• Wakimoto N., Yokoyama A., Okabe-Kado J., Nagata K., Motoyoshi K., Honma Y. Combined analysis of differentiation inhibitory factor nm23-H1 and nm23-H2 as prognostic factors in acute myeloid leukaemia. Br. J. Cancer 1998, in press
   PubMed Web of Science ®Google Scholar
• Wakimoto N., Yokoyama A., Mukai Y, Kuwada N., Yamashita T., Matumura T., Nakamura Y., Katatani Y, Nagata N., Okabe-Kado J., Honma Y., Motoyoshi K. Serial changes of differentiation inhibitory factor nm23 expression in monoblastic crisis of chronic myelogenous leukemia. Int. J. Hematol. 1998, in press
   PubMed Web of Science ®Google Scholar
• Aryee D. N.T., Simonitsch I., Mosberger I., Kos K., Mann G., Schlogl E., Potschger U., Gander H., Radaszkiewicz T., Kovar H. Variability of nm23-H1/NDPK-A expression in human lymphomas and its relation to tumour aggressiveness. Br. J. Cancer 1996; 74: 1693–1698
   PubMed Web of Science ®Google Scholar
• Ji L., Arcinas M., Boxer L. M. The transcription factor, nm23H2, binds to and activates the translocated c-myc alle in Burkitt's lymphoma. J. Biol. Chem. 1995; 270: 13392–13398
   PubMed Web of Science ®Google Scholar
• Inoue K., Sugiyama H., Ogawa H., Nakagawa M., Yamagami T., Miwa H., Kita K., Hiraoka A., Masaoka T., Nasu K., Kyo T., Dohy H., Nakauchi H., Ishidate T., Akiyama T., Kishimoto T. WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia. Blood 1994; 88: 3071–3079
   Google Scholar
• Ishikawa N., Taniguchi-Seto H., Munakata Y, Takagi Y, Shimada N., Kimura N. Multiple transcripts for rat nucleoside diphosphate kinase a isoform are structurally categorized into two groups that exhitit cell-specific expression and distinct translation potential. J. Biol. Chem. 1997; 272: 3289–3295
   PubMed Web of Science ®Google Scholar
• Paravicini G., Steinmayr M., Andre E., Becker-Andre M. The metastasis suppressor candidate necleotide diphosphate kinase nm23 specifically interacts with members of the ROR/RZR nuclear orphan receptor subfamily. Biochem. Biophys. Res. Commun. 1996; 227: 82–87
   PubMed Web of Science ®Google Scholar
• Leung S.-M., Hightower L. E. A 16-kDa protein functions as a new regulatory protein for Hsc70 molecular chaperone and is identified as a member of the nm23/nucleo-side diphosphate kinase family. J. Biol. Chem. 1997; 272: 2607–2614
   PubMed Web of Science ®Google Scholar
• Freije J. M.R, Lawrence J. A., Hollingshead M. G., Dela Rosa A., Narayanan V., Grever M., Sausville E. A., Paull K., Steeg P S. Identification of compounds with preferential inhibitory activity against low-Nm23-expressing human breast carcinoma and melanoma cell lines. Nature Med. 1997; 3: 395–401
   PubMed Web of Science ®Google Scholar