Improved methods and standards for telomerase detection: quantitative histopathology using antibody staining

References

• Apple SK. Variability in gross and microscopic pathology reporting in excisional biopsies of breast cancer tissue. Breast J.. 2006; 12:145–149.
   PubMedGoogle Scholar
• Atha DH, Miller K, Sanow AD, Xu J, Hess JL, Wu OC, Wang W, Srivastava S, Highsmith WE. High-throughput analysis of telomerase by capillary electrophoresis. Electrophoresis. 2003; 24:109–114.
   PubMed Web of Science ®Google Scholar
• Blackburn EH. Structure and function of telomeres. Nature. 1991; 350:569–572.
   PubMed Web of Science ®Google Scholar
• Colgin LM, Wilkinson C, Englezou A, Kilian A, Robinson MO, Reddel RR. The hTERT a splice variant is a dominant negative inhibitor of telomerase activity. Neoplasia. 2000; 2:426–432.
   PubMed Web of Science ®Google Scholar
• Collan Y. Morphometry in pathology: another look at diagnostic histopathology. Pathol. Res. Pract.. 1984; 179:189–192.
   PubMedGoogle Scholar
• Elkak AE, Meligonis G, Salhab M, Mitchell B, Blake JRS, Newbold RF, Mokbel K. hTERT protein expression is independent of clinicopathological parameters and cMyc protein expression in human breast cancer. J. Carcinogen. 2005; 4:17–25.
   PubMedGoogle Scholar
• Emrich T, Chang SY, Karl G, Panzinger B, Santini C. Quantitative detection of telomerase components by real-time on-line PCR analysis with the LightCycler. Methods Mol. Biol.. 2002; 191:99–108.
   PubMedGoogle Scholar
• Gallant ND, Michael KE, Garcia AJ. Cell adhesion strengthening: contributions of adhesive area, integrin binding and focal adhesion assembly. Mol. Biol. Cell. 2005; 16:4329–4340.
   PubMed Web of Science ®Google Scholar
• Gil J, Wu HS. Applications of image analysis to anatomic pathology: realities and promises. Cancer Invest.. 2003; 21:950–959.
   PubMed Web of Science ®Google Scholar
• Hess JL, Atha DH, Xu J, Highsmith WE. Telomerase activity measurement in magnetically captured epithelial cells: comparison of slab-gel and capillary electrophoresis. Electrophoresis. 2004; 25:1852–1859.
   PubMed Web of Science ®Google Scholar
• Jakupciak JP, Barker PE, Wang W, Srivastava S, Atha DH. Standards for telomerase assays: TRAP/PCR, Real-time TRAP/PCR, and hTERTmRNA/RT-PCR. Clin. Chem.. 2005; 51:1443–1450.
   PubMed Web of Science ®Google Scholar
• Jakupciak JP, Wang W, Barker PE, Srivastava S, Atha DH. Analytical validation of telomerase activity for cancer early detection. J. Mol. Diagn.. 2004; 6:157–165.
   PubMed Web of Science ®Google Scholar
• KimNW, PiatyszekMA, ProwseKR, HarleyCB, WestMD, HoPL, CovielloGM, WrightWE, WeinrichSL, ShayJW1994; Specific association of human telomerase activity with immortal cells and cancer. . Science266: : 2011–2015. .
   Google Scholar
• Levy MZ, Allsopp RC, Futcher AB, Greider CW, Harley CB. Telomere end-replication problem and cell aging. J. Mol. Biol.. 1992; 225:951–960.
   PubMed Web of Science ®Google Scholar
• Maruvada P, Wang W, Wagner PD, Srivastava S. Biomarkers in molecular medicine: cancer detection and diagnosis. Biotechniques. April2005; (Suppl.): 9–15.
   PubMedGoogle Scholar
• McGruder BM, Atha DH, Wang W, Huppi K, Wei WQ, Abnet CC, Qiao YL, Dawsey SM, Taylor PR, Jakupciak JP. Real-time telomerase assay of less-invasively collected esophageal cell samples. Cancer Lett. 2006; 244:91–100.
   PubMed Web of Science ®Google Scholar
• O'Connell CD, Atha DH, Jakupciak JP. Standards for validation of cancer biomarkers. Cancer Biomarkers. 2005; 1:233–239.
   PubMedGoogle Scholar
• Obyashiki JH, Ohyashiki K, Toyama K, Shay JW. A nonradioactive, fluorescence-based telomeric repeat amplification protocol to detect and quantitate telomerase activity. TIG. 1996; 12:395–396.
   PubMedGoogle Scholar
• Piatyszek MA, Kim NW, Weinrich SL, Hiyama K, Hiyama E, Wright WE, Shay JW. Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol. Methods Cell Sci.. 1995; 17:1–15.
   Google Scholar
• Shay JW (1999) Telomerase and cancer In: Molecular Pathology of Early Cancer Srivastava S, Hensen DE, Gazdar A. IOS Press, Washington, DC. 405–424.
   Google Scholar
• Sokal RR, Rohlf FJ (1995) Biometry: the Principles and Practice of Statistics in Biological Research. 3rd W.H. Freeman, New York. 409–419.
   Google Scholar
• Taylor CR. The total test approach to standardization of immunohistochemistry. Arch. Pathol. Lab. Med.. 2000; 124:945–951.
   PubMed Web of Science ®Google Scholar
• Tosi P, Cottier H. What's new in quantitative pathology? Past developments and outlook. Pathol. Res. Pract.. 1989; 184:652–655.
   PubMedGoogle Scholar
• Wang SL, Wu MT, Yang SF, Chan HM, Chai CY. Computerized nuclear morphometry in thyroid follicular neoplasms. Pathol. Int.. 2005; 55:703–706.
   PubMedGoogle Scholar
• Wu Y-L, Dudognon C, Nguyen E, Hillion J, Pendino F, Tarkanyi I, Aradi J, Lanotte M, Tong J-H, Chen G-Q, Segal-Bendirdjian S. Immunodetection of human telomerase reverse-transcriptase (hTERT) re-appraised: nucleolin and telomerase cross paths. J. Cell Sci.. 2006; 119:2797–2806.
   PubMed Web of Science ®Google Scholar
• Xiao Y (2006) Antibodies to human telomerase reverse transcriptase. SAIC Patent application filed June 26, 2006, attorney docket number 000479.00163.
   Google Scholar
• Xiao Y, Gao X, Gannot G, Emmert-Buck MR, Srivastava S, Wagner PD, Amos MD, Barker PE. Quantitation of HER2 and telomerase biomarkers in solid tumors with IgY antibodies and nanocrystal detection. Int. J. Cancer. 2008; 122:2178–2186.
   PubMedGoogle Scholar
• Yi X, Shay JW, Wright WE. Quantitation of telomerase components and hTERT mRNA splicing patterns in immortal human cells. Nucl. Acids Res.. 2001; 29:4818–4825.
   PubMed Web of Science ®Google Scholar
• Yi X, White DM, Aisner DL, Baur JA, Wright WE, Shay JW. An alternate splicing variant of the telomerase catalytic subunit inhibits telomerase activity. Neoplasia. 2000; 2:433–440.
   PubMed Web of Science ®Google Scholar