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Research Article

The roles of canonical and non-canonical Wnt signaling in human de-differentiated articular chondrocytes

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Pages 53-65 | Accepted 15 Apr 2013, Published online: 01 Aug 2013

References

  • Adler PN, Lee H (2001). Frizzled signaling and cell-cell interactions in planar polarity. Curr. Opin. Cell. Biol. 13: 635–640.
  • Bafico A, Liu G, Yaniv A, Gazit A, Aaronson SA (2001). Novel mechanism of Wnt signaling inhibition mediated by Dickkopf-1 interaction with LRP6. Nat. Cell. Biol. 3: 683–686.
  • Bányai L, Patthy L (1999). The NTR module: domains of netrins secreted frizzled related proteins and type I procollagen C-proteinase enhancer protein are homologous with tissue inhibitors of metalloproteases. Protein Sci. 8: 1636–1642.
  • Blom B, Brochbank S, Van Lent P, Van Beuningen HM, Geurts J, Takahashi N, Van Der Kraan PM, Van De Loo FA, Schreurs BW, Clements K, Newham P, Van Den Berg WB (2009). Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1. Arthr. Rheum. 60: 501–512.
  • Boutros M, Mlodzik M (1999). Disheveled: at the crossroads of divergent intracellular signaling pathways. Mech. Dev. 83: 27–37.
  • Brodkin K, Garcia A, Levenston M (2004). Chondrocytes phenotypes on different extracellular matrix monolayers. Biomaterials 25: 5929–5938.
  • Chen M, Zhu M, Awad H, Li TF, Sheu TJ, Boyce BF, Chen D, O’Keefe RJ (2008). Inhibition of beta-catenin signaling causes defects in postnatal cartilage development. J. Cell Sci. 121: 1455–1465.
  • Church VL, Francis-West P (2002). Wnt signaling during limb development. Int. J. Dev. Biol. 46 : 927–936.
  • Day TF, Guo X, Garrett-Beal L, Yang Y (2005). Wnt beta-catenin signaling in mesenchymal progenitor controls osteoblast and chondrocyte differentiation during vertebrates skeletogenesis. Dev. Cell 8: 739–750.
  • Dell’Accio F, De Bari C, Luyten F (2001). Molecular markers predictive of the capacity of expanded human articular chondrocytes to form stable cartilage in vivo. Arthr. Rheum. 44: 1608–1619.
  • Dong Y, Drissi H, Chen M, Zuscik MJ, Schwarz EM, O’Keefe RJ (2005). Wnt-mediated regulation of chondrocyte maturation: modulation by TGF-beta. J. Cell. Biochem. 95: 1057–1068.
  • Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C (1998). Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 391: 357–362.
  • Gornall AG, Bardawill CJ, David MM (1949). Determination of serum proteins by means of the biuret reaction. J. Biol. Chem. 177:751–766.
  • Hartmann C (2007). Skeletal development-Wnts are in control. Mol. Cell 24: 177–184.
  • Hwang SG, Ryu JH, Kim IC, Jho EH, Jung HC, Kim K, Kim SJ, Chun JS (2004). Regulation of beta- catenin signaling and maintenance of chondrocyte differentiation by ubiquitin dependent proteosomal degradation of alpha-catenin. J. Biol. Chem. 279: 26597–26604.
  • Hwang SG, Yu SS, Lee SW, Chun JS (2005a). Wnt-7a causes loss of differentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms. J. Biol. Chem. 280: 12758–12765.
  • Hwang SG, Yu SS, Lee SW, Chun JS (2005b). Wnt 3a regulates chondrocytes differentiation via c-Jun/AP1 pathway. FEBS Lett. 579: 4837–4842.
  • Jones SE, Jomary C (2002). Secreted frizzled-related proteins: searching for relationships and patterns. BioEssays 24: 811–820.
  • Kohn AD, Moon RT (2005). Wnt and calcium signaling: beta-catenin-independent pathways. Cell Calcium 38: 439–446
  • Kuhl M, Sheldahl LC, Park M, Miller JR, Moon RT (2000). The Wnt/Ca2 + pathway: a new vertebrate Wnt signaling pathway takes shape. Trends Genet. 16: 279–283.
  • L’Allemain G (2006). Role of the Wnt pathway in oncogenesis. Bull. Cancer 93: 88–97.
  • Laadhar L, Zitouni M, Kallel-Sellami M, Mahjoub M, Sellami S, Makni S (2007). Physiopathology of osteoarthritis: from normal cartilage to osteoarthritic cartilage: risk factors and inflammatory mechanisms. Rev. Med. Int. 28: 531–536.
  • Ladher RK, Church VL, Allen S, Robson L, Abdelfattah A, Brown NA, Hattersley G, Rosen V, Luyten FP, Dale L, Francis-West PH (2000). Cloning and expression of the Wnt antagonists Sfrp-2 and Frzb during chick development. Dev. Biol. 218: 183–198.
  • Lane NE, Nevitt MC, Lui LY, De Leon P, Corr M (2007). Wnt signaling antagonists are potential prognostic biomarkers for the progression of radiographic hip osteoarthritis in elderly Caucasian women. Arthr. Rheum. 56: 3319–3325.
  • Laughlin J, Dowling B, Chapman K, Marcelline L, Mustafa Z, Southam L , Ferreira A, Ciesielski C, Carson DA, Corr M (2004). Functional variant within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females. Proc. Natl. Acad. Sci. USA 101: 9757–9762.
  • Lories RJ, Peeters J, Bakker A, Tylzanowski P, Derese I, Schrooten J , Thomas JT, Luyten FP (2007). Articular cartilage and biomechanical properties of the long bones in Frzb-knockout mice. Arthr. Rheum. 56 : 4095–4103.
  • Lu ZF, Zandieh Doulabi B, Wuisman PI, Bank RA, Helder MN (2007). Differentiation of adipose stem cells by nucleus pulposus cells: configuration effect. Biochem. Biophys. Res. Commun. 359:991–996.
  • Miller JR, Hocking AM, Brown JD, Moon RT (1999). Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2 + pathways. Oncogene 18: 7860–7872.
  • Nagase H, Kashiwagi M (2003). Aggrecanases and cartilage matrix degradation. Arthr. Res. 5: 94–103.
  • Ozawa M, Baribault H, Kemler R (1989). The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO J. 8: 1711–1717.
  • Papathanasiou I, Malizos K, Tsezou A (2009). Low- density lipoprotein receptor-related protein 5 (LRP5) expression in human osteoarthritic chondrocytes. J. Ortho. Res. 28: 348–353.
  • Poole AR, Kobayashi M, Yasuda T, Laverty S, Mwale F, Kojima T , Sakai T, Wahl C, El-Madawy S, Webb G, Tchetina E, Wu W (2002). Type II collagen degradation and its regulation in articular cartilage in osteoarthritis. Ann. Rheum. Dis. 61: 78–81.
  • Ryu JH, Chun JS (2006). Opposing roles of Wnt-5A and Wnt-11 in interleukin-1β regulation of type II collagen expression in articular chondrocytes. J. Biol. Chem. 281: 22039–22047.
  • Salvat C, Pigenet A, Humbert L, Berenbaum F, Thirion S (2005). Immature murine articular chondrocytes in primary culture: a new tool for investigating cartilage. Osteoarthr. Cart. 13: 243–249.
  • Sassi N, Laadhar L, Allouche M, Zandieh-Doulabi B, Hamdoun M, Klein-Nulend J, Makni S, Sellami S (2013). Wnt signaling is involved in human articular chondrocyte de-differentiation in vitro. Biotech. & Histochem. 89: 29–40.
  • Shortkoff S, Yates KE (2007). Alteration of matrix glycosaminoglycans diminishes articular chondrocyte response to a canonical Wnt signal. Osteoarthr. Cart. 15: 147–154.
  • Tamamura Y, Otani T, Kanatani N, Koyama E, Kitagaki J, Komori T, Yamada Y, Costantini F, Wakisaka S, Pacifici M, Iwamoto M, Enomoto-Iwamoto M (2005). Developmental regulation of Wnt-beta catenin signals is required for growth plate assembly cartilage integrity and endochondral ossification. J. Biol. Chem. 280: 19185–19195. The Wnt gene homepage [www stanford edu/˜rnusse/Wntwindow html].
  • Van Beuningen HM, Stoop R, Buma P, Takahashi N, Van Der Kraan PM, Van Den Berg WB (2002). Phenotypic differences in murine chondrocyte cell lines from mature articular cartilage. Osteoarthr. Cart. 10: 977–986.
  • Weng LH, Wang CJ, Ko JY, Sun YC, Su YS, Wang FS (2009). Inflammation induction of Dickkopf-1 mediates chondrocyte apoptosis in osteoarthritic joint. Osteoarthr. Cart. 17: 933–943.
  • Weng LH, Wang CJ, Ko JY, Sun YC, Wang FS (2010). Control of Dkk-1 ameliorates chondrocyte apoptosis cartilage destruction and subchondral bone deterioration in osteoarthritic knees. Arthr. Rheum. 62: 1393–1402.
  • Yuasa T, Otani T, Koike T, Iwamoto M, Enomoto-Iwamoto M (2008). Wnt/beta-catenin signaling stimulates matrix catabolic genes and activity in articular chondrocytes: its possible role in joint degeneration. Lab. Invest. 88: 264–274.
  • Zhu M, Chen M, Zuscik M, Wu Q, Wang YJ, Rosier RN, O’Keefe R J, Chen D (2008). Inhibition of beta-catenin signaling in articular chondrocytes results in articular cartilage destruction. Arthr. Rheum. 7: 2053–2064.

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