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Original Article

Methadone vs. L-alpha-acetylmethadol (LAAM) in the Treatment of Opiate Addiction: A Meta-Analysis of the Randomized, Controlled TriaIs

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Pages 339-349 | Received 09 Jan 1997, Accepted 27 Jun 1997, Published online: 10 Jul 2009

References

  • Gfroerer J C. Office of Applied Studies, SAMHSA Preliminary Estimates From the 1995 National Household Survey on Drug Abuse. SAMHSA, Rockville, MD 1996, Advance Report Number 18
  • Office of National Drug Control Policy. Pulse Check: National Trends in Drug Abuse. Executive Office of the President, Spring, Washington, DC 1996
  • Stimmel B, Goldberg J, Rotkopf E, et al. Ability to remain abstinent after methadone detoxification: a six-year study. JAMA 1977; 237: 1216–1220
  • Ball J C., Lange W R., Myers C P., et al. Reducing the risk of AIDS through methadone maintenance. J Health Soc Behav 1988; 29: 214–226
  • Hubbard R L., Marsden M E., Rachel J V., et al. Drug Abuse Treatment: A National Study of Effectiveness. University of North Care lina Press, Chapel Hill, NC 1989
  • Institute of Medicine. Federal Regulation of Methadone Treatment. National Academy Press, Washington, DC 1995
  • Farrell M, Ward J, Mattick R, et al. Methadone maintenance treatment in opiate dependence: a review. BMJ 1994; 304: 997–1001
  • Ling W, Rawson R A., Compton M A. Substitution pharmacotherapies for opioid addiction: from methadone to LAAM and buprenorphine. J Psychoactive Drugs April-June 1994; 26: 119–128
  • Senay E C., Dorus W, Renault P F. Methadyl acetate and methadone an open comparison. JAMA 1977; 237: 138–142
  • Ling W, Klett J, Roderic D G. A cooperative clinical study of methadyl acetate. Arch Gen Psychiatry 1978; 35: 345–353
  • Ling W, Charuvastra C, Kaim S C., et al. Methadyl acetate and methadone as maintenance treatments for heroin addicts. Arch Gen Psychiatry 1976; 33: 709–719
  • Prendergast M L., Grella C, Perry S M., et al. Leve-alpha-acetyl-methadol (LAAM), clinical, research, and policy issues of a new pharmacotherapy for opioid addiction. J Psychoactive Drugs 1995; 27: 239–246
  • Tennant F S., Rawson R A., Pumprey E, et al. Clinical experiences with 959 opioid-dependent patients treated with l-alpha acetylmethadol (LAAM). J Subst Abuse Treat 1986; 3: 195–202
  • Fleiss J L. The statistical basis of meta-analysis. Stat Methods Med Res 1993; 2: 121–145
  • Mostellar F, Laird N. Some statistical methods for combining results. Int J Technol Assess Health Care 1990; 6: 5–30
  • Chalmers T C. A method for assessing the quality of randomized controlled trials. Control Clin Trials 1981; 2: 31–49
  • Marcovici M, O'Brien C, McLellan A T., et al. A clinical controlled study of l-alpha-acetylmethadol in the treatment of narcotic addiction. Am J Psychiatry 1981; 138: 234–236
  • Zaks A, Fink M, Freedman A M. Levomethadyl in maintenance treatment of opiate dependence. JAMA 1972; 220: 811–813
  • Freedman R R., Czertko G. A comparison of thriceweekly LAAM and daily methadone in employed heroin addicts. Drug Alcohol Depend 1981; 8: 215–222
  • Savage C, Karp E G., Curran S E., et al. Methadone/LAAM maintenance: a comparison study. Compr Psychiatry 1976; 17: 415–424
  • Sorensen J L., Hargreaves W A., Weinberg J A. Withdrawal from heroin in three or six weeks. Arch Gen Psychiatry 1982; 39: 167–171
  • Jaffe J A., Se Y EC, Schuster C R., et al. Methadyl acetate vs methadone: a double-blind study in heroin users. JAMA1972; 222: 437–442
  • Karp-Gelernter E, Savage C, McCabe O L. Evaluation of clinic schedule for LAAM and methadone: a controlled study. Int J Addict 1982; 17: 805–813
  • Crowlcy T J., Macdonald M J., Wagner J E., et al. Acetylmethadol vs methadone: human mood and me tility. Psychopharmacology 1985; 86: 458–463
  • Jaffe J H., Schuster C H., Smith B, et al. Comparison of acetylmethadol and methadone in the treatment of long-term heroin users: a pilot study. JAMA 1970; 211: 1834–1836
  • Jaffe J H., Senay E C. Methadone and l-methadyl acetate: use in management of narcotics addicts. JAMA 1971; 216: 1303–1305
  • Panell J, Charuvastra V C., Ouren J. Methadyl acetate vs. methadone: the experience of one hospital. Med J Aust 1977; 2: 150–152
  • Strain E C., Stitzer M L., Liebson I A., et al. Dose-response effects of methadone in the treatment of opioid dependence. Ann Intern Med 1993; 199: 23–27
  • Reitman D., Sacks H S., Chalmers T C. Technical quality assessment of randomized controlled trials (abstract). Control Clin Trials 1987; 8282
  • Brown B S., Watters J K., Inglemart A S. Methadone maitainence dosage levels and program retention. Am J Drug Alcohol Abuse 1982–83; 9: 129–139
  • Sackett D, Haynes R B., Guyatt G., et al. Clinical Epidemiology: A Basic Science2nd Edition. Little, Brown, Boston, MA 1991
  • Moreland J, Thomson M A. Efficacy of electromy-ographic biofeedback compared to conventional physical therapy for upper extremity function following stroke: a research overview and meta-analysis. Phys Ther 1994; 74: 534–547
  • Borzak S, Ftidker P M. Discordance between meta-analyses and large-scale randomized, controlled trials. Ann Intern Med 1995; 123: 873–877

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