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Clinical Research and Regulatory Affairs Volume 11, 1994 - Issue 3-4

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Research Article

An Application of the Population Approach to Animal Pharmacokinetics During Drug Development

E. I. Ette Center for Drug Evaluation and Research Food and Drug Administration, Biopharmaceutics Division, Rockville, MD, 20857, USA

A. W. Kelman Dept. of Medicine & therapeutics, Western Infirmary Gardiner Institute, Glasgow, G11 6NT, UK

C. A. Howie Dept. of Medicine & therapeutics, Western Infirmary Gardiner Institute, Glasgow, G11 6NT, UK

B. Whiting Dept. of Medicine & therapeutics, Western Infirmary Gardiner Institute, Glasgow, G11 6NT, UK

Pages 243-255 | Published online: 28 Sep 2008

Cite this article
https://doi.org/10.3109/10601339409035945

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Beal S. L., Sheiner L. B. NONMEM Users Guide, Parts I—IV. Division of Clinical Pharmacology, University of California, San Francisco 1979–1989
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Sheiner L. B., Rosenberg B., Marathe V. V. Estimation of population characteristics of pharmacokinetic parameters from routine clinical data. J. Pharmacokin. Biopharm. 1977; 5: 445–479
PubMedGoogle Scholar
Vocci F., Farber T. Extrapolation of animal toxicity data to man. Regul. Toxicol. Pharmacol 1988; 8: 389–398
PubMed Web of Science ®Google Scholar

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