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Original Article

Alendronate-loaded microparticles for improvement of intestinal cellular absorption

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Pages 37-48 | Received 27 Sep 2009, Accepted 01 Feb 2010, Published online: 18 May 2010

References

  • Anić B, Grazio S. (2006). Current osteoporosis treatment: reasons for adding vitamin D to alendronate. Reumatizam, 53, 63–65.
  • Birnbaum DT, Brannon-Peppas L. (2003). Microparticle Drug Delivery Systems, Totowa, NJ: Humana Press.
  • Doclane V, Vilivalam VD. (1998). Pharmaceutical application of chitosan. Pharm Sci Technol Today, 1, 246–253.
  • Ehtezazi T, Washington C, Melia CD. (1999). Determination of the internal morphology of poly(d,l-lactide) microspheres using stereological methods. J Control Release, 57, 301–314.
  • Ehtezazi T, Washington C. (2000). Controlled release of macromolecules from PLA microspheres using porous structure topology. J Control Release, 68, 361–372.
  • Ekelund K, Osth K, Pahlstorp C, Bjork E, Ulvenlund S, Johansson F. (2005). Correlation between epithelial toxicity and surfactant structure as derived from the effects of polyethyleneoxide surfactants on Caco-2 cell monolayers and pig nasal mucosa. J Pharm Sci, 94, 730–744.
  • Furubayashi T, Kamaguchi A, Kawaharada K, Masaoka Y, Kataoka M, Yamashita S, Higashi Y, Sakane T. (2007). Kinetic model to predict the absorption of nasally applied drugs from in vitro transcellular permeability of drugs. Biol Pharm Bull, 30, 1007–1010.
  • Graham D. (1998). Excess gastric ulcers are associated with alendronate therapy. Am J Gastroenterol, 93, 1395–1396.
  • Graham D, Malaty H. (1999). Alendronate gastric ulcers. Aliment Pharmacol Ther, 13, 515–519.
  • Graham DY. (2002). What the gastroenterologist should know about the gastrointestinal safety profiles of bisphosphonates. Dig Dis Sci, 47, 1665–1678.
  • Hafner A, Lovric J, Voinovich D, Filipovic-Grcic J. (2009). Melatonin-loaded lecithin/chitosan nanoparticles: physicochemical characterisation and permeability through Caco-2 cell monolayers. Int J Pharm, 381, 205–213.
  • Henriksen I, Green KL, Smart JD, Smistad G, Karlsen J. (1996). Bioadhesion of hydrated chitosans: an in vitro and in vivo study. Int J Pharm, 145, 246–253.
  • Hussain MR, Maji TK. (2008). Preparation of genipin cross-linked chitosan–gelatin microcapsules for encapsulation of Zanthoxylum limonella oil (ZLO) using salting-out method. J Microencap, 25, 414–420.
  • Jain RA. (2000). The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials, 21, 2475–2490.
  • Karamustafa F, çelebi N. (2008). Development of an oral microemulsion formulation of alendronate: effects of oil and co-surfactant type on phase behaviour. J Microencap, 25, 315–323.
  • Kimmel DB. (2007). Mechanism of action, pharmacokinetic and pharmacodynamic profile, and clinical applications of nitrogen-containing bisphophonates. J Dent Res, 86, 1022–1033.
  • Lehr CM, Bouwstra JA, Schacht EH, Junginger HE. (1992). In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers. Int J Pharm, 78, 43–48.
  • Lufkin E, Argueta R, Whitaker MD, Cameron AL, Wong VH, Egan KS. (1994). Pamidronate: an unrecognized problem in gastrointestinal tolerability. Osteopor Int, 4, 320–322.
  • Maconi G, Porro G. (1995). Multiple ulcerative esophagitis caused by alendronate. Am J Gastroenterol, 90, 1889–1890.
  • Mao S, Germershaus O, Fischer D, Linn T, Schnepf R, Kissel T. (2005). Uptake and transport of PEG-graft-trimethyl-chitosan copolymer-insulin nanocomplexes by epithelial cells. Pharm Res, 22, 2058–2068.
  • Mora-Huertas CE, Fessi H, Elaissari A. (2009). Polymer-based nanocapsules for drug delivery. Int J Pharm, 385, 113–142.
  • Perugini P, Genta I, Conti B, Modena T, Pavanetto F. (2001). Long-term release of clodronate from biodegradable microspheres. AAPS PharmSci Tech, 2, E10.
  • Porras A, Holland S, Gertz B. (1999). Pharmacokinetics of alendronate. Clin Pharmacokinet, 36, 315–328.
  • Ringe JD, Farahmand P, Schacht E, Rozehnal A. (2007). Superiority of a combined treatment of alendronate and alfacalcidol compared to the combination of alendronate and plain vitamin D or alfacalcidol alone in established postmenopausal or male osteoporosis (AAC-Trial). Rheumatol Int, 27, 425–434.
  • Sadeghi AMM, Dorkoosh FA, Avadi MR, Weinhold M, Bayat A, Delie F. (2008). Permeation enhancer effect of chitosan and chitosan derivatives: comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells. Eur J Pharm Biopharm, 70, 270–278.
  • Sakuma S, Matsumoto T, Yamashita S, Wang Y, Lu ZR. (2007). Conjug-ation of poorly absorptive drugs with mucoadhseive polymers for the improvement of oral absorption of drugs. J Control Release, 123, 195–202.
  • Samdancioglu S, Calis S, Summu M, Hincal AA. (2006). Formulation and in vitro evaluation of bisphosphonate loaded microspheres for implantation in osteolysis. Drug Dev Ind Pharm, 32, 473–481.
  • Singh J, Pandit S, Bramwell VW, Alpar HO. (2006). Diphtheria toxoid loaded poly- (ϵ-caprolactone) nanoparticles as mucosal vaccine delivery systems. Methods, 38, 96–105.
  • Tenenbaum H, Shelemay A, Girard B, Zohar R, Fritz P. (2002). Bisphosphonates and periodontics: potential applications for regulation of bone mass in the periodontium and other therapeutic/diagnotic uses. J Periodon, 73, 813–822.
  • Tian J, Yu J, Sun X. (2008). Chitosan microspheres as candidate plasmid vaccine carrier for oral immunisation of Japanese flounder (Paralichthys olivaceus). Vet Immun Immunopath, 126, 220–229.
  • Trickler W, Nagvekar AA, Dash AK. (2008). A novel microparticle formulation for sustained paclitaxel delivery. AAPS PharmSci Tech, 9, 486–493.
  • Viswanathan NB, Thomas PA, Pandit JK, Kulkarni MG, Mashelkar RA. (1999). Preparation of non-porous microspheres with high entrapement efficiency of proteins by a (water-in-oil)-in-oil emulsion technique. J Control Release, 58, 9–20.
  • Weidenauer U, Bodmer D, Kissel T. (2003). Microencapsulation of hydrophilic drug substance using biodegradable polyesters. Part I: evaluation of different techniques for the encapsulation of pamidronate di-sodium salt. J Microencap, 20, 509–524.
  • You SK, Kwon HH, Lee JM, Shin SC, Cho CW. (2009). Studies on the formation of hydrophobic ion-pairing complex of alendronate. Arch Pharm Res, 32, 1055–1060.

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