Formulation and evaluation of flurbiprofen-loaded genipin cross-linked gelatin microspheres for intra-articular delivery

References

• Chemtob C, Assimacopoulos T, Chaumeil JC. (1988). Preparation and characteristics of gelatin microspheres. Drug Dev Ind Pharm, 14, 1359–1374.
   Web of Science ®Google Scholar
• Coimbra PA, De Sousa HC, Gil MH. (2008). Preparation and characterization of flurbiprofen-loaded poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microspheres. J Microencapsul, 25, 170–178.
   PubMed Web of Science ®Google Scholar
• Costa P, Lobo JMS. (2001). Modeling and comparison of dissolution profiles. Eur J Pharm Sci, 13, 123–133.
   PubMed Web of Science ®Google Scholar
• Cryer B, Feldman M. (1998). Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugs. Am J Med, 104, 413–421.
   PubMed Web of Science ®Google Scholar
• Esposito E, Cortesi R, Nastruzzi C. (1996). Gelatin microspheres: influence of preparation parameters and thermal treatment on chemico-physical and biopharmaceutical properties. Biomaterials, 17, 2009–2020.
   PubMed Web of Science ®Google Scholar
• Fernández-Carballido A, Herrero-Vanrell R, Molina-Martínez IT, Pastoriza P. (2004). Biodegradable ibuprofen-loaded PLGA microspheres for intraarticular administration. Effect of Labrafil addition on release in vitro. Int J Pharm, 279, 33–41.
   PubMed Web of Science ®Google Scholar
• Griffini A, Vandelli MA, Seghizzi R, Muuci A, Pifferi G. (1996). Pharmaceutical evaluation of gelatin microspheres crosslinked with D,L-glyceraldehyde. Determination of residuals of the preparation procedure. Pharm Pharmacol Lett, 6, 16–18.
   Google Scholar
• Hansra P, Moran EL, Fornasier VL, Bogoch ER. (2000). Carrageenan-induced arthritis in the rat. Inflammation, 24, 141–155.
   PubMed Web of Science ®Google Scholar
• Insel PA. (1996). Analgesic-antipyretic and anti-inflammatory agents and drug employed in the treatment of gout. In: Hardman JG, Limbird LE, editors. Goodman & Gilman’s the Pharmacological Basis of Therapeutics. New York: McGraw-Hill.
   Google Scholar
• Jin J, Song M, Hourston DJ. (2004). Novel chitosan-based films cross-linked by genipin with improved physical properties. Biomacromolecules, 5, 162–168.
   PubMed Web of Science ®Google Scholar
• Kawadkar J, Chauhan MK. (2012). Intra-articular delivery of genipin cross-linked chitosan microspheres of flurbiprofen: preparation, characterization, in vitro and in vivo studies. Eur J Pharm Biopharm, 81, 563–572.
   PubMed Web of Science ®Google Scholar
• Kim S, Nimni ME, Yang Z, Han B. (2005). Chitosan/gelatin-based films crosslinked by proanthocyanidin. J Biomed Mater Res Part B Appl Biomater, 75, 442–450.
   PubMed Web of Science ®Google Scholar
• Larsen C, Ostergaard J, Larsen SW, Jensen H, Jacobsen S, Lindegaard C, Andersen PH. (2008). Intra-articular depot formulation principles: role in the management of postoperative pain and arthritic disorders. J Pharm Sci, 97, 4622–4654.
   PubMed Web of Science ®Google Scholar
• Li JK, Wang N, Wu XS. (1998). Gelatin nanoencapsulation of protein/peptide drugs using an emulsifier-free emulsion method. J Microencapsul, 15, 163–172.
   PubMed Web of Science ®Google Scholar
• Liang HC, Chang WH, Lin KJ, Sung HW. (2003). Genipin-crosslinked gelatin microspheres as a drug carrier for intramuscular administration: in vitro and in vivo studies. J Biomed Mater Res A, 65, 271–282.
   PubMed Web of Science ®Google Scholar
• Liang LS, Wong W, Burt HM. (2005). Pharmacokinetic study of methotrexate following intra-articular injection of methotrexate loaded poly(L-lactic acid) microspheres in rabbits. J Pharm Sci, 94, 1204–1215.
   PubMed Web of Science ®Google Scholar
• Liggins RT, Cruz T, Min W, Liang L, Hunter WL, Burt HM. (2004). Intra-articular treatment of arthritis with microsphere formulations of paclitaxel: biocompatibility and efficacy determinations in rabbits. Inflamm Res, 53, 363–372.
   PubMed Web of Science ®Google Scholar
• Lu Y, Zhang G, Sun D, Zhong Y. (2007). Preparation and evaluation of biodegradable flubiprofen gelatin micro-spheres for intra-articular administration. J Microencapsul, 24, 515–524.
   PubMed Web of Science ®Google Scholar
• Masuda K. (1984). Pharmacology of the eye. In: Sears ML, editor. Handbook of Experimental Pharmacology. Berlin: Springer Verlag.
   Google Scholar
• Mi FL, Tan YC, Liang HC, Huang RN, Sung HW. (2001). In vitro evaluation of a chitosan membrane cross-linked with genipin. J Biomater Sci Polym Ed, 12, 835–850.
   PubMed Web of Science ®Google Scholar
• Natarajan V, Krithica N, Madhan B, Sehgal PK. (2011). Formulation and evaluation of quercetin polycaprolactone microspheres for the treatment of rheumatoid arthritis. J Pharm Sci, 100, 195–205.
   PubMed Web of Science ®Google Scholar
• Park KM, Gao ZG, Kim CK. (1997). Assay of flurbiprofen in rat plasma using HPLC with fluorescence detection. J Liq Chrom Technol, 20, 1849–1855.
   Web of Science ®Google Scholar
• Patricia AC, Herminio CD, Maria HG. (2009). Preparation and characterization of flurbiprofen-loaded poly(3-hydroxybuty-rate-co-3-hydroxyvalerate) microsphere. J Microencapsul, 25, 170–178.
   Web of Science ®Google Scholar
• Ranjha NM, Khan IU, Naseem S. (2009). Encapsulation and characterization of flurbiprofen loaded poly(ϵ-caprolactone)-poly(vinylpyrolidone) blend microspheres by solvent evaporation method. J Sol Gel Technol, 1957–1967.
   Google Scholar
• Raymond G, Degennaro M, Mikeal R. (1990). Preparation of gelatin: phenytoin sodium microspheres: an in vitro and in vivo evaluation. Drug Dev Ind Pharm, 16, 1025–1051.
   Web of Science ®Google Scholar
• Ritger P, Peppas N. (1987). A simple equation for description of solute release II. Fickian and anomalous release from swellable devices. J Control Release, 5, 37–42.
   Google Scholar
• Saravanan M, Bhaskar K, Maharajan G, Pillai KS. (2004). Ultrasonically controlled release and targeted delivery of diclofenac sodium via gelatin magnetic microspheres. Int J Pharm, 283, 71–82.
   PubMed Web of Science ®Google Scholar
• Saravanan M, Bhaskar K, Maharajan G, Pillai KS. (2011). Development of gelatin microspheres loaded with diclofenac sodium for intra-articular administration. J Drug Target, 19, 96–103.
   PubMed Web of Science ®Google Scholar
• Silvio LD, Gaurav N, Kayser MV, Braden M, Downes S. (1994). Biodegradable microspheres: A new delivery system for growth hormone. Biomaterials, 15, 931–936.
   PubMed Web of Science ®Google Scholar
• Thakkar H, Sharma RK, Mishra AK, Chuttani K, Murthy RS. (2004). Efficacy of chitosan microspheres for controlled intra-articular delivery of celecoxib in inflamed joints. J Pharm Pharmacol, 56, 1091–1099.
   PubMed Web of Science ®Google Scholar
• Tsikas D, Brunner G. (1990). Quantitative determination of paraffin oil in blood by capillary gas chromatography. J High Resolut Chromatogr, 13, 244–246.
   Google Scholar
• Ugwoke MI, Kinget R. (1998). Influence of processing variables on the properties of gelatin microspheres prepared by the emulsification solvent extraction technique. J Microencapsul, 15, 273–281.
   PubMed Web of Science ®Google Scholar
• Vandelli MA, Rivasi F, Guerra P, Forni F, Arletti R. (2001). Gelatin microspheres crosslinked with D,L-glyceraldehyde as a potential drug delivery system: preparation, characterisation, in vitro and in vivo studies. Int J Pharm, 215, 175–184.
   PubMed Web of Science ®Google Scholar
• Yao CH, Liu BS, Hsu SH, Chen YS. (2005). Calvarial bone response to a tricalcium phosphate-genipin crosslinked gelatin composite. Biomaterials, 26, 3065–3074.
   PubMed Web of Science ®Google Scholar
• Yuan Y, Chesnutt BM, Utturkar G, Haggard WO, Yang Y, Ong JL, Bumgardnera JD. (2007). The effect of cross-linking of chitosan microspheres with genipin on protein release. Carbohyd Polym, 68, 561–567.
   Web of Science ®Google Scholar