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Review Article

Smart approaches to glucose-responsive drug delivery

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Pages 651-655 | Received 05 May 2015, Accepted 25 May 2015, Published online: 09 Oct 2015

References

  • Patterson CC, Dahlquist GG, Gyurus E, et al. Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005–20: a multicentre prospective registration study. Lancet 2009;373:2027–33
  • Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic. Nature 2001;414:782–7
  • Wild S, Roglic G, Green A, et al. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047–53
  • DeFronzo RA, Jacot E, Jequier E, et al. The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization. Diabetes 1981;30:1000–7
  • Daneman D. Type 1 diabetes. Lancet 2006;367:847–58
  • Knowler WC, Barrett-Connor E, Fowler SE, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002;346:393–403
  • de Veciana M, Major CA, Morgan MA, et al. Postprandial versus preprandial blood glucose monitoring in women with gestational diabetes mellitus requiring insulin therapy. N Engl J Med 1995;333:1237–41
  • American Diabetes A. Diagnosis and classification of diabetes mellitus. Diabetes Care 2014;37:S81–90
  • DeWitt DE, Hirsch IB. Outpatient insulin therapy in type 1 and type 2 diabetes mellitus: scientific review. JAMA 2003;289:2254–64
  • Peyrot M, Barnett AH, Meneghini LF, Schumm-Draeger PM. Insulin adherence behaviours and barriers in the multinational Global Attitudes of Patients and Physicians in Insulin Therapy study. Diabet Med 2012;29:682–9
  • McCoy RG, Van Houten HK, Ziegenfuss JY, et al. Increased mortality of patients with diabetes reporting severe hypoglycemia. Diabetes Care 2012;35:1897–901
  • Muggeo M, Zoppini G, Bonora E, et al. Fasting plasma glucose variability predicts 10-year survival of type 2 diabetic patients: the Verona Diabetes Study. Diabetes Care 2000;23:45–50
  • Hirsch IB. Insulin analogues. N Engl J Med 2005;352:174–83
  • Owens DR. New horizons – alternative routes for insulin therapy. Nat Rev Drug Discov 2002;1:529–40
  • Chertok B, Webber MJ, Succi MD, Langer R. Drug delivery interfaces in the 21st century: from science fiction ideas to viable technologies. Mol Pharm 2013;10:3531–43
  • Qiu Y, Park K. Environment-sensitive hydrogels for drug delivery. Adv Drug Deliv Rev 2001;53:321–39
  • Bratlie KM, York RL, Invernale MA, et al. Materials for diabetes therapeutics. Adv Healthcare Mater 2012;1:267–84
  • Jimenez JL, Nettleton EJ, Bouchard M, et al. The protofilament structure of insulin amyloid fibrils. Proc Natl Acad Sci USA 2002;99:9196–201
  • Weinzimer SA, Steil GM, Swan KL, et al. Fully automated closed-loop insulin delivery versus semiautomated hybrid control in pediatric patients with type 1 diabetes using an artificial pancreas. Diabetes Care 2008;31:934–9
  • El-Khatib FH, Jiang J, Damiano ER. Adaptive closed-loop control provides blood-glucose regulation using dual subcutaneous insulin and glucagon infusion in diabetic Swine. J Diabetes Sci Technol 2007;1:181–92
  • Russell SJ, El-Khatib FH, Sinha M, et al. Outpatient glycemic control with a bionic pancreas in type 1 diabetes. N Engl J Med 2014;371:313–25
  • Brown L, Munoz C, Siemer L, et al. Controlled release of insulin from polymer matrices. Control of diabetes in rats. Diabetes 1986;35:692–7
  • Brown L, Siemer L, Munoz C, Langer R. Controlled release of insulin from polymer matrices. In vitro kinetics. Diabetes 1986;35:684–91
  • Veiseh O, Tang BC, Whitehead KA, et al. Managing diabetes with nanomedicine: challenges and opportunities. Nat Rev Drug Discov 2015;14:45–57
  • Bankar SB, Bule MV, Singhal RS, Ananthanarayan L. Glucose oxidase – an overview. Biotechnol Adv 2009;27:489–501
  • Ishihara K, Kobayashi M, Ishimaru N, Shinohara I. Glucose-induced permeation control of insulin through a complex membrane consisting of immobilized glucose-oxidase and a poly(amine). Polym J 1984;16:625–31
  • Albin G, Horbett TA, Ratner BD. Glucose sensitive membranes for controlled delivery of insulin: insulin transport studies. J Control Release 1985;2:153–64
  • Ishihara K, Matsui K. Glucose-responsive insulin release from polymer capsule. J Polym Sci Part C – Polym Lett 1986;24:413–17
  • Ravaine V, Ancla C, Catargi B. Chemically controlled closed-loop insulin delivery. J Control Release 2008;132:2–11
  • Traitel T, Cohen Y, Kost J. Characterization of glucose-sensitive insulin release systems in simulated in vivo conditions. Biomaterials 2000;21:1679–87
  • Zhang K, Wu XY. Modulated insulin permeation across a glucose-sensitive polymeric composite membrane. J Control Release 2002;80:169–78
  • Podual K, Doyle FJ, Peppas NA. Glucose-sensitivity of glucose oxidase-containing cationic copolymer hydrogels having poly(ethylene glycol) grafts. J Control Release 2000;67:9–17
  • Gu Z, Dang TT, Ma M, et al. Glucose-responsive microgels integrated with enzyme nanocapsules for closed-loop insulin delivery. ACS Nano 2013;7:6758–66
  • Ito Y, Casolaro M, Kono K, Imanishi Y. An insulin-releasing system that is responsive to glucose. J Control Release 1989;10:195–203
  • Cartier S, Horbett TA, Ratner BD. Glucose-sensitive membrane coated porous filters for control of hydraulic permeability and insulin delivery from a pressurized reservoir. J Membr Sci 1995;106:17–24
  • Chu LY, Li Y, Zhu JH, et al. Control of pore size and permeability of a glucose-responsive gating membrane for insulin delivery. J Control Release 2004;97:43–53
  • Hassan CM, Doyle FJ, Peppas NA. Dynamic behavior of glucose-responsive poly(methacrylic acid-g-ethylene glycol) hydrogels. Macromolecules 1997;30:6166–73
  • Kang SI, Bae YH. A sulfonamide based glucose-responsive hydrogel with covalently immobilized glucose oxidase and catalase. J Control Release 2003;86:115–21
  • Heller J, Chang AC, Rodd G, Grodsky GM. Release of Insulin from Ph-Sensitive Poly(Ortho Esters). J Control Release 1990;13:295–302
  • Fischel-Ghodsian F, Brown L, Mathiowitz E, et al. Enzymatically controlled drug delivery. Proc Natl Acad Sci USA 1988;85:2403–6
  • Wu YH, Hu HM, Hu JM, Liu SY. Glucose-regulated insulin release from acid-disintegrable microgels covalently immobilized with glucose oxidase and catalase. Macromol Rapid Commun 2012;33:1852–60
  • Gu Z, Aimetti AA, Wang Q, et al. Injectable nano-network for glucose-mediated insulin delivery. ACS Nano 2013;7:4194–201
  • Tai W, Mo R, Di J, et al. Bio-inspired synthetic nanovesicles for glucose-responsive release of insulin. Biomacromolecules 2014;15:3495–502
  • Sharon N, Lis H. Lectins: cell-agglutinating and sugar-specific proteins. Science 1972;177:949–59
  • Brownlee M, Cerami A. A glucose-controlled insulin-delivery system: semisynthetic insulin bound to lectin. Science 1979;206:1190–1
  • Pai CM, Bae YH, Mack EJ, et al. Concanavalin – a microspheres for a self-regulating insulin delivery system. J Pharm Sci 1992;81:532–6
  • Makino K, Mack EJ, Okano T, Kim SW. A microcapsule self-regulating delivery system for insulin. J Control Release 1990;12:235–9
  • Seminoff LA, Olsen GB, Kim SW. A self-regulating insulin delivery system. 1. Characterization of a synthetic glycosylated insulin derivative. Int J Pharm 1989;54:241–9
  • Seminoff LA, Gleeson JM, Zheng J, et al. A self-regulating insulin delivery system. 2. Invivo characteristics of a synthetic glycosylated insulin. Int J Pharm 1989;54:251–7
  • Holmberg DL, Jeong SY, Kim SW, Mcrea JC. Development of a self-regulating insulin delivery system. Vet Surg 1987;16:92
  • Sung WK, Chaul MP, Makino K, et al. Self-regulated glycosylated insulin delivery. J Control Release 1990;11:193–201
  • Taylor MJ, Tanna S, Taylor PM, Adams G. The delivery of insulin from aqueous and non-aqueous reservoirs governed by a glucose sensitive gel membrane. J Drug Target 1995;3:209–16
  • Nakamae K, Miyata T, Jikihara A, Hoffman AS. Formation of poly(glucosyloxyethyl methacrylate)-concanavalin – a complex and its glucose-sensitivity. J Biomater Sci – Polym Ed 1994;6:79–90
  • Yin R, Tong Z, Yang D, Nie J. Glucose and pH dual-responsive concanavalin A based microhydrogels for insulin delivery. Int J Biol Macromol 2011;49:1137–42
  • Yin R, Tong Z, Yang D, Nie J. Glucose-responsive insulin delivery microhydrogels from methacrylated dextran/concanavalin A: preparation and in vitro release study. Carbohydr Polym 2012;89:117–23
  • Miyata T, Jikihara A, Nakamae K, Hoffman AS. Preparation of poly(2-glucosyloxyethyl methacrylate)concanavalin A complex hydrogel and its glucose-sensitivity. Macromol Chem Phys 1996;197:1135–46
  • Zhang R, Tang M, Bowyer A, et al. Synthesis and characterization of a D-glucose sensitive hydrogel based on CM-dextran and concanavalin A. React Funct Polym 2006;66:757–67
  • Obaidat AA, Park K. Characterization of glucose dependent gel-sol phase transition of the polymeric glucose-concanavalin A hydrogel system. Pharm Res 1996;13:989–95
  • Lee SJ, Park K. Synthesis and characterization of sol–gel phase-reversible hydrogels sensitive to glucose. J Mol Recog 1996;9:549–57
  • Obaidat AA, Park K. Characterization of protein release through glucose-sensitive hydrogel membranes. Biomaterials 1997;18:801–6
  • Wu S, Huang X, Du X. Glucose- and pH-responsive controlled release of cargo from protein-gated carbohydrate-functionalized mesoporous silica nanocontainers. Angew Chem Int Ed Engl 2013;52:5580–4
  • Miyata T, Jikihara A, Nakamae K, Hoffman AS. Preparation of reversibly glucose-responsive hydrogels by covalent immobilization of lectin in polymer networks having pendant glucose. J Biomater Sci – Polym Ed 2004;15:1085–98
  • Tanna S, Taylor MJ, Adams G. Insulin delivery governed by covalently modified lectin-glycogen gels sensitive to glucose. J Pharm Pharmacol 1999;51:1093–8
  • Tanna S, Sahota T, Clark J, Taylor MJ. Covalent coupling of concanavalin A to a Carbopol 934P and 941P carrier in glucose-sensitive gels for delivery of insulin. J Pharm Pharmacol 2002;54:1461–9
  • Kataoka K, Miyazaki H, Bunya M, et al. Totally synthetic polymer gels responding to external glucose concentration: their preparation and application to on-off regulation of insulin release. J Am Chem Soc 1998;120:12694–5
  • James TD, Sandanayake KRAS, Shinkai S. Saccharide sensing with molecular receptors based on boronic acid. Angew Chem Int Ed 1996;35:1910–22
  • Kataoka K, Miyazaki H, Okano T, Sakurai Y. Sensitive glucose-induced change of the lower critical solution temperature of poly[N,N-dimethylacrylamide-Co-3-(acrylamido)phenyl-boronic acid] in physiological saline. Macromolecules 1994;27:1061–2
  • Kitano S, Koyama Y, Kataoka K, et al. A novel drug delivery system utilizing a glucose responsive polymer complex between poly(vinyl alcohol) and poly(N-vinyl-2-pyrrolidone) with a phenylboronic acid moiety. J Control Release 1992;19:162–70
  • Shiino D, Murata Y, Kataoka K, et al. Preparation and characterization of a glucose-responsive insulin-releasing polymer device. Biomaterials 1994;15:121–8
  • Matsumoto A, Ikeda S, Harada A, Kataoka K. Glucose-responsive polymer bearing a novel phenylborate derivative as a glucose-sensing moiety operating at physiological pH conditions. Biomacromolecules 2003;4:1410–16
  • Yan J, Springsteen G, Deeter S, Wang BH. The relationship among pK(a),pH, and binding constants in the interactions between boronic acids and diols – it is not as simple as it appears. Tetrahedron 2004;60:11205–9
  • Shiino D, Murata Y, Kubo A, et al. Amine containing phenylboronic acid gel for glucose-responsive insulin release under physiological pH. J Control Release 1995;37:269–76
  • Langer R, Anderson DG, Gu Z, Aimetti AA. Self-regulated peptide hydrogel for insulin delivery. United States: Massachusetts Institute of Technology; 2013
  • Chou DH, Webber MJ, Tang BC, et al. Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates. Proc Natl Acad Sci USA 2015;112:2401–6
  • Hoeg-Jensen T, Havelund S, Nielsen PK, Markussen J. Reversible insulin self-assembly under carbohydrate control. J Am Chem Soc 2005;127:6158–9
  • Hoeg-Jensen T, Ridderberg S, Havelund S, et al. Insulins with built-in glucose sensors for glucose responsive insulin release. J Pept Sci 2005;11:339–46

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