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Original Article

Thioaptamer-conjugated CD44-targeted delivery system for the treatment of breast cancer in vitro and in vivo

, , , , , , , , & show all
Pages 359-371 | Received 01 Mar 2015, Accepted 27 Jul 2015, Published online: 21 Aug 2015

References

  • Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA Cancer J Clin 2015;65:5–29
  • Shen H, Mittal V, Ferrari M, Chang J. Delivery of gene silencing agents for breast cancer therapy. Breast Cancer Res 2013;15:205. doi: 10.1186/bcr3413
  • Munagala R, Aqil F, Gupta RC. Promising molecular targeted therapies in breast cancer. Indian J Pharmacol 2011;43:236–45
  • Escudero-Abarca BI, Suh SH, Moore MD, et al. Selection, characterization and application of nucleic acid aptamers for the capture and detection of human norovirus strains. PLoS One 2014;9:e106805
  • Rozenblum GT, Kaufman T, Vitullo AD. Myelin basic protein and a multiple sclerosis-related MBP-peptide bind to oligonucleotides. Mol Ther Nucleic Acids 2014;3:e192
  • Ding F, Guo S, Xie M, et al. Diagnostic applications of gastric carcinoma cell aptamers in vitro and in vivo. Talanta 2015;134:30–6
  • Kaur G, Roy I. Therapeutic applications of aptamers. Expert Opin Invest Drugs 2008;17:43–60
  • Kong HY, Byun J. Nucleic acid aptamers: new methods for selection, stabilization, and application in biomedical science. Biomol Ther (Seoul) 2013;21:423–34
  • Pendergrast PS, Marsh HN, Grate D, et al. Nucleic acid aptamers for target validation and therapeutic applications. J Biomol Technol 2005;16:224–34
  • Somasunderam A, Thiviyanathan V, Tanaka T, et al. Combinatorial selection of DNA thioaptamers targeted to the HA binding domain of human CD44. Biochemistry 2010;49:9106–12
  • Peach RJ, Hollenbaugh D, Stamenkovic I, Aruffo A. Identification of hyaluronic acid binding sites in the extracellular domain of CD44. J Cell Biol 1993;122:257–64
  • Anand MT, Kumar S. CD44: a key player in breast cancer. Indian J Cancer 2014;51:247–50
  • Lila MA, Siew JS, Zakaria H, et al. Cell targeting in anti-cancer gene therapy. Malay J Med Sci 2004;11:9–23
  • Louderbough JM, Schroeder JA. Understanding the dual nature of CD44 in breast cancer progression. Mol Cancer Res 2011;9:1573–86
  • Leth-Larsen R, Terp MG, Christensen AG, et al. Functional heterogeneity within the CD44 high human breast cancer stem cell-like compartment reveals a gene signature predictive of distant metastasis. Mol Med 2012;18:1109–21
  • Shirure VS, Liu T, Delgadillo LF, et al. CD44 variant isoforms expressed by breast cancer cells are functional E-selectin ligands under flow conditions. Am J Physiol Cell Physiol 2015;308:C68–78
  • Yu CC, Tsai LL, Wang ML, et al. miR145 targets the SOX9/ADAM17 axis to inhibit tumor-initiating cells and IL-6-mediated paracrine effects in head and neck cancer. Cancer Res 2013;73:3425–40
  • Medimegh I, Omrane I, Privat M, et al. MicroRNAs expression in triple negative vs non triple negative breast cancer in Tunisia: interaction with clinical outcome. PLoS One 2014;9:e111877
  • Yang F, Zhang W, Shen Y, Guan X. Identification of dysregulated microRNAs in triple-negative breast cancer (Review). Int J Oncol 2015;46:927–32
  • Wu X, Tai Z, Zhu Q, et al. Study on the prostate cancer-targeting mechanism of aptamer-modified nanoparticles and their potential anticancer effect in vivo. Int J Nanomedicine 2014;9:5431–40
  • Liu J, Shapiro JI. Endocytosis and signal transduction: basic science update. Biol Res Nurs 2003;5:117–28
  • Kim HR, Gil S, Andrieux K, et al. Low-density lipoprotein receptor-mediated endocytosis of PEGylated nanoparticles in rat brain endothelial cells. Cell Mol Life Sci 2007;64:356–64
  • Visser CC, Stevanovic S, Heleen Voorwinden L, et al. Validation of the transferrin receptor for drug targeting to brain capillary endothelial cells in vitro. J Drug Target 2004;12:145–50
  • Kim SJ, Shin JY, Lee KD, et al. MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7. Breast Cancer Res 2012;14:R14
  • Xin H, Jiang X, Gu J, et al. Angiopep-conjugated poly(ethylene glycol)-co-poly(epsilon-caprolactone) nanoparticles as dual-targeting drug delivery system for brain glioma. Biomaterials 2011;32:4293–305
  • Li YT, Chua MJ, Kunnath AP, Chowdhury EH. Reversing multidrug resistance in breast cancer cells by silencing ABC transporter genes with nanoparticle-facilitated delivery of target siRNAs. Int J Nanomedicine 2012;7:2473–81
  • Zuo L, Li L, Wang Q, et al. Mammaglobin as a potential molecular target for breast cancer drug delivery. Cancer Cell Int 2009;9:8. doi: 10.1186/1475-2867-9-8

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