Evaluation of Arterial Blood Pressure and Renal Sodium Handling in a Model of Female Rats in Persistent Estrus

REFERENCES

• Farah L, Lazenby AJ, Boots LR, Azziz R. Prevalence of polycystic ovary syndrome in women seeking treatment from community electrologists. Alabama Professional Electrology Association Study Group. J Reprod Med 1999;44:870–874.
   PubMed Web of Science ®Google Scholar
• Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 2004;89:2745–2749.
   PubMed Web of Science ®Google Scholar
• Rotterdam ESHRE-ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 2004;81:19–25.
   Web of Science ®Google Scholar
• Chen MJ, Yang WS, Yang JH, Chen CL, Ho HN, Yang YS. Relationship between androgen levels and blood pressure in young women with polycystic ovary syndrome. Hypertension 2007;49:1442–1447.
   PubMed Web of Science ®Google Scholar
• Cheung LP, Ma RC, Lam PM, Lok IH, Haines CJ, So WY, Cardiovascular risks and metabolic syndrome in Hong Kong Chinese women with polycystic ovary syndrome. Human Reprod 2008;23:1431–1438.
   PubMed Web of Science ®Google Scholar
• Dahlgren E, Janson PO, Johansson S, Lapidus L, Lindstedt G, Tengborn L. Hemostatic and metabolic variables in women with polycystic ovary syndrome. Fertil Steril 1994;61:455–460.
   PubMed Web of Science ®Google Scholar
• Wild RA. Long-term health consequences of PCOS. Hum Reprod Update 2002;8:231–241.
   PubMed Web of Science ®Google Scholar
• Legro RS. Polycystic ovary syndrome and cardiovascular disease: a premature association? Endocr Rev 2003;24:302–312.
   PubMed Web of Science ®Google Scholar
• Ehrmann DA, Liljenquist DR, Kasza K, Azziz R, Legro RS, Ghazzi MN; PCOS/Troglitazone Study Group. Prevalence and predictors of the metabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2006;91:48–53.
   PubMed Web of Science ®Google Scholar
• Strazzullo P, Galletti F, Barba G. Altered renal handling of sodium in human hypertension: short review of the evidence. Hypertension 2003;41:1000–1005.
   PubMed Web of Science ®Google Scholar
• Frey BA, Grisk O, Bandelow N, Wussow S, Bie P, Rettig R. Sodium homeostasis in transplanted rats with a spontaneously hypertensive rat kidney. Am Physiol Regul Integr Comp Physiol 2000;279:1099–1104.
   Google Scholar
• Barraclough CA. Production of anovulatory, sterile rats by single injections of testosterone propionate. Endocrinology 1961;68:62–67.
   PubMed Web of Science ®Google Scholar
• da Silva BB, Lopes-Costa PV, dos Santos AR, Pires CG, Borges CS, Gontijo JA. Evaluation of Ki-67 antigen expression in the zona reticularis of the adrenal cortex of female rats in persistent estrus. Hum Reprod 2009;24:705–709.
   PubMed Web of Science ®Google Scholar
• Wrenn TR, Wood JR, Bitman J. Oestrogen responses of rats neonatally sterilized with steroids. J Endocrinol 1969;45:415–420.
   PubMed Web of Science ®Google Scholar
• Lovenberg W. Techniques for measurements of blood pressure 1987. Hypertension 9:15–16.
   Google Scholar
• Xavier F, Magalhães AMF, Gontijo JAR 2000. Effect of inhibition of nitric oxide synthase on blood pressure and renal sodium handling in renal denervated rats. Braz J Med Biol Res 33:347–354.
   PubMed Web of Science ®Google Scholar
• Michelotto JB, Carvalheira JB, Saad MJ, Gontijo JA. Effects of intracerebro-ventricular insulin microinjection on renal sodium handling in kidney-denervated rats. Brain Res Bull 2002;57:613–618.
   PubMed Web of Science ®Google Scholar
• Boer PA, Morelli JM, Figueiredo JF, Gontijo JA. Early altered renal sodium handling determined by lithium clearance in spontaneously hypertensive rats (SHR): Role of renal nerves. Life Sci 2005;76:1805–1815.
   PubMed Web of Science ®Google Scholar
• Gontijo JAR, Garcia WE, Figueiredo JF, Silva-Netto CR, Furtado MRF. Renal sodium handling after noradrenergic stimulation of the lateral hypothalamus area in rats. Braz J Med Biol Res 1992;25:937–942.
   PubMed Web of Science ®Google Scholar
• Furlan FC, Marshal PS, Macedo RF, Carvalheira JB, Michelotto JB, Gontijo JAR. Acute intracerebroventricular insulin microinjection after nitric oxide synthase inhibition of renal sodium handling in rats. Life Sci 2003;72:2561–2569.
   PubMed Web of Science ®Google Scholar
• Agrest A. Categorical Data Analysis. 2nd ed. New York: John Wiley and Sons Inc., 2002.
   Google Scholar
• Mannerås L, Cajander S, Holmäng A, A new rat model exhibiting both ovarian and metabolic characteristics of polycystic ovary syndrome. Endocrinology 2007;148: 3781–3791.
   PubMed Web of Science ®Google Scholar
• Singh KB. Persistent estrus rat models of polycystic ovary disease: an update. Fertil Steril 2005;84 suppl 2:1228–1234.
   PubMedGoogle Scholar
• da Silva BB, Rocha Gontijo JA, Crété AR, de Jesus Simões M. Evaluation of body weight in androgenized female rats. Clin Exp Obstet Gynecol 2002;29:97–99.
   PubMedGoogle Scholar
• da Silva BB, Lopes-Costa PV, Rosal MA, Pires CG, dos Santos LG, Gontijo JA, Morphological and morphometric analysis of the adrenal cortex of androgenized female rats. Gynecol Obstet Invest 2007;64:44–48.
   PubMed Web of Science ®Google Scholar
• Nogueira LT, da Silva BB. Effects of raloxifene on the mammary epithelium of female rats in persistent estrus. Gynecol Endocrinol 2008;25(6):357–361.
   Web of Science ®Google Scholar
• Stener-Victorin E, Ploj K, Larsson BM, Holmäng A. Rats with steroid-induced polycystic ovaries develop hypertension and increased sympathetic nervous system activity. Reprod Biol Endocrinol 2005;3:44.
   PubMed Web of Science ®Google Scholar
• Silva-Antonialli MM, Tostes RC, Fernandes L, Fior-Chadi DR, Akamine EH, Carvalho MH, Fortes ZB, Nigro D. A lower ratio of AT1/AT2 receptors of angiotensin II is found in female than in male spontaneously hypertensive rats. Cardiovasc Res 2004; 62:587–583.
   PubMed Web of Science ®Google Scholar
• Pawlikowski M, Winczyk K, Sledz B. Immunohistochemical detection of angiotensin receptors AT1 and AT2 in adrenal tumors. Folia Histochem Cytobiol 2008;46:51–55.
   PubMed Web of Science ®Google Scholar
• Nielsen CB, Flyvbjerg A, Bruun JM, Forman A, Wogensen L, Thomsen K. Decreases in renal functional reserve and proximal tubular fluid output in conscious oophorectomized rats: normalization with sex hormone substitution. J Am Soc Nephrol 2003;14:3102–3110.
   PubMed Web of Science ®Google Scholar