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Original Article

Treatment of Isolated Systolic Hypertension in the Elderly: The Syst-Eur Trial

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Pages 491-497 | Published online: 03 Jul 2009

References

  • Staessen J., Amery A., Fagard R. Isolated systolic hypertension in the elderly. J Hypertens. 1990; 8: 393–405
  • SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program. JAMA 1991; 265: 3255–3264, (SHEP)
  • Amery A., Birkenhager W., Bulpitt C. J., et al. Syst-Eur. A multicentre trial on the treatment of isolated systolic hypertension in the elderly: objectives protocol and organization. Aging Clin Exp Res. 1991; 3: 287–302
  • Staessen J. A., Fagard R., Thijs L., et al. Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension (correction published in Lancet 1997, volume 350, November 29, p 1636). Lancet 1997; 350: 757–764
  • Staessen J. A., Fagard R., Thijs L., et al. Subgroup and per-protocol analysis of the randomized European trial on isolated systolic hypertension in the elderly. Arch Intern Med. 1998; 158: 1681–1691
  • Staessen J. A., Thijs L., Fagard R. H., et al. Calcium channel blockade and cardiovascular prognosis in the European trial on isolated systolic hypertension. Hypertension 1998, in press

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