Measurement of urinary F₂-isoprostanes by gas chromatography-mass spectrometry is confounded by interfering substances

References

• Morrow JD, Awad JA, Kato T, Takahashi K, Badr KF, Roberts LJ, 2nd, Burk RF. Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation. J Clin Invest 1992;90:2502–2507.
   PubMed Web of Science ®Google Scholar
• Jahn U, Galano JM, Durand T. Beyond prostaglandins— chemistry and biology of cyclic oxygenated metabolites formed by free-radical pathways from polyunsaturated fatty acids. Angew Chem Int Ed Engl 2008;47:5894–5955.
   PubMed Web of Science ®Google Scholar
• Klein T, Reutter F, Schweer H, Seyberth HW, Nusing RM. Generation of the isoprostane 8-epi-prostaglandin F2alpha in vitro and in vivo via the cyclooxygenases. J Pharmacol Exp Ther 1997;282:1658–1665.
   PubMed Web of Science ®Google Scholar
• Montuschi P, Barnes PJ, Roberts LJ, 2nd. Isoprostanes: markers and mediators of oxidative stress. Faseb J 2004;18:1791–1800.
   PubMed Web of Science ®Google Scholar
• Morrow JD, Awad JA, Boss HJ, Blair IA, Roberts LJ, 2nd. Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids. Proc Natl Acad Sci USA 1992;89:10721–10725.
   PubMed Web of Science ®Google Scholar
• Basu S, Helmersson J. Factors regulating isoprostane formation in vivo. Antioxid Redox Signal 2005;7:221–235.
   PubMed Web of Science ®Google Scholar
• Kadiiska MB, Gladen BC, Baird DD, Germolec D, Graham LB, Parker CE, Nyska A, Wachsman JT, Ames BN, Basu S, Brot N, Fitzgerald GA, Floyd RA, George M, Heinecke JW, Hatch GE, Hensley K, Lawson JA, Marnett LJ, Morrow JD, Murray DM, Plastaras J, Roberts LJ, 2nd, Rokach J, Shigenaga MK, Sohal RS, Sun J, Tice RR, Van Thiel DH, Wellner D, Walter PB, Tomer KB, Mason RP, Barrett JC. Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Free Radic Biol Med 2005;38:698–710.
   PubMed Web of Science ®Google Scholar
• Wang Z, Ciabattoni G, Creminon C, Lawson J, Fitzgerald GA, Patrono C, Maclouf J. Immunological characterization of urinary 8-epi-prostaglandin F2 alpha excretion in man. J Pharmacol Exp Ther 1995;275:94–100.
   PubMed Web of Science ®Google Scholar
• Helmersson J, Basu S. F2-isoprostane excretion rate and diurnal variation in human urine. Prostaglandins Leukot Essent Fatty Acids 1999;61:203–205.
   PubMed Web of Science ®Google Scholar
• Bessard J, Cracowski JL, Stanke-Labesque F, Bessard G. Determination of isoprostaglandin F2alpha type III in human urine by gas chromatography-electronic impact mass spectrometry Comparison with enzyme immunoassay. J Chromatogr B Biomed Sci Appl 2001;754:333–343.
   PubMed Web of Science ®Google Scholar
• Mas E, Michel F, Guy A, Bultel V, Falquet Y, Chardon P, Rossi JC, Cristol JP, Durand T. Quantification of urinary F(2)-isoprostanes with 4(RS)-F(4t)-neuroprostane as an internal standard using gas chromatography-mass spectrometry application to polytraumatized patients. J Chromatogr B Analyt Technol Biomed Life Sci 2008;872:133–140.
   PubMedGoogle Scholar
• Mori TA, Croft KD, Puddey IB, Beilin LJ. An improved method for the measurement of urinary and plasma F2-isoprostanes using gas chromatography-mass spectrometry. Anal Biochem 1999;268:117–125.
   PubMed Web of Science ®Google Scholar
• Tsikas D, Schwedhelm E, Fauler J, Gutzki FM, Mayatepek E, Frolich JC. Specific and rapid quantification of 8-iso-prostaglandin F2alpha in urine of healthy humans and patients with Zellweger syndrome by gas chromatography-tandem mass spectrometry. J Chromatogr B Biomed Sci Appl 1998;716:7–17.
   PubMed Web of Science ®Google Scholar
• Li H, Lawson JA, Reilly M, Adiyaman M, Hwang SW, Rokach J, FitzGerald GA. Quantitative high performance liquid chromatography/tandem mass spectrometric analysis of the four classes of F(2)-isoprostanes in human urine. Proc Natl Acad Sci USA 1999;96:13381–13386.
   PubMed Web of Science ®Google Scholar
• Bohnstedt KC, Karlberg B, Basun H, Schmidt S. Porous graphitic carbon chromatography-tandem mass spectrometry for the study of isoprostanes in human cerebrospinal fluid. J Chromatogr B Analyt Technol Biomed Life Sci 2005;827:39–43.
   PubMedGoogle Scholar
• Davies SS, Zackert W, Luo Y, Cunningham CC, Frisard M, Roberts LJ, 2nd. Quantification of dinor,dihydro metabolites of F(2)-isoprostanes in urine by liquid chromatography/ tandem mass spectrometry. Anal Biochem 2006;348:185–191.
   PubMedGoogle Scholar
• Proudfoot J, Barden A, Mori TA, Burke V, Croft KD, Beilin LJ, Puddey IB. Measurement of urinary F(2)-isoprostanes as markers of in vivo lipid peroxidation—A comparison of enzyme immunoassay with gas chromatography/mass spectrometry. Anal Biochem 1999;272:209–215.
   PubMed Web of Science ®Google Scholar
• Tsikas D, Schwedhelm E, Suchy MT, Niemann J, Gutzki FM, Erpenbeck VJ, Hohlfeld JM, Surdacki A, Frolich JC. Divergence in urinary 8-iso-PGF(2alpha) (iPF(2alpha)-III, 15-F(2t)-IsoP) levels from gas chromatography-tandem mass spectrometry quantification after thin-layer chromatography and immunoaffinity column chromatography reveals heterogeneity of 8-iso-PGF(2alpha) Possible methodological, mechanistic and clinical implications. J Chromatogr B Analyt Technol Biomed Life Sci 2003;794:237–255.
   PubMedGoogle Scholar
• Oger C, Brinkmann Y, Bouazzaoui S, Durand T, Galano JM. Stereocontrolled access to isoprostanes via a bicyclo[3.3.0] octene framework. Org Lett 2008;10:5087–5090.
   PubMed Web of Science ®Google Scholar
• Tsai IJ, Croft KD, Mori TA, Falck JR, Beilin LJ, Puddey IB, Barden AE. 20-HETE and F2-isoprostanes in the metabolic syndrome: the effect of weight reduction. Free Radic Biol Med 2009;46:263–270.
   PubMed Web of Science ®Google Scholar
• Milne GL, Yin H, Brooks JD, Sanchez S, Jackson Roberts L, 2nd, Morrow JD. Quantification of F2-isoprostanes in biological fluids and tissues as a measure of oxidant stress. Methods Enzymol 2007;433:113–126.
   PubMed Web of Science ®Google Scholar
• Morrow JD, Roberts LJ, 2nd. Mass spectrometric quan tification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress. Methods Enzymol 1999;300:3–12.
   PubMed Web of Science ®Google Scholar
• Nourooz-Zadeh J, Gopaul NK, Barrow S, Mallet AI, Anggard EE. Analysis of F2-isoprostanes as indicators of non-enzymatic lipid peroxidation in vivo by gas chromatography-mass spectrometry: development of a solid-phase extraction procedure. J Chromatogr B Biomed Appl 1995;667:199–208.
   PubMed Web of Science ®Google Scholar
• Lawson JA, Li H, Rokach J, Adiyaman M, Hwang SW, Khanapure SP, FitzGerald GA. Identification of two major F2 isoprostanes, 8,12-iso- and 5-epi-8, 12-iso-isoprostane F2alpha-VI, in human urine. J Biol Chem 1998;273:29295–29301.
   PubMedGoogle Scholar
• Tsikas D. Application of gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry to assess in vivo synthesis of prostaglandins, thromboxane, leukotrienes, isoprostanes and related compounds in humans. J Chromatogr B Biomed Sci Appl 1998;717:201–245.
   PubMedGoogle Scholar
• Waugh RJ, Morrow JD, Roberts LJ, 2nd, Murphy RC. Identification and relative quantitation of F2-isoprostane regioisomers formed in vivo in the rat. Free Radic Biol Med 1997;23:943–954.
   PubMed Web of Science ®Google Scholar
• Fessel JP, Porter NA, Moore KP, Sheller JR, Roberts LJ, 2nd. Discovery of lipid peroxidation products formed in vivo with a substituted tetrahydrofuran ring (isofurans) that are favored by increased oxygen tension. Proc Natl Acad Sci USA 2002;99:16713–16718.
   PubMed Web of Science ®Google Scholar
• Song WL, Lawson JA, Reilly D, Rokach J, Chang CT, Giasson B, FitzGerald GA. Neurofurans, novel indices of oxidant stress derived from docosahexaenoic acid. J Biol Chem 2008;283:6–16.
   PubMedGoogle Scholar
• VanRollins M, Woltjer RL, Yin H, Morrow JD, Montine TJ. F2-dihomo-isoprostanes arise from free radical attack on adrenic acid. J Lipid Res 2008;49:995–1005.
   PubMed Web of Science ®Google Scholar
• Musiek ES, Cha JK, Yin H, Zackert WE, Terry ES, Porter NA, Montine TJ, Morrow JD. Quantification of F-ring isoprostane-like compounds (F4-neuroprostanes) derived from docosahexaenoic acid in vivo in humans by a stable isotope dilution mass spectrometric assay. J Chromatogr B Analyt Technol Biomed Life Sci 2004;799:95–102.
   PubMed Web of Science ®Google Scholar
• Lee CY, Jenner AM, Halliwell B. Rapid preparation of human urine and plasma samples for analysis of F2-isoprostanes by gas chromatography-mass spectrometry. Biochem Biophys Res Commun 2004;320:696–702.
   PubMed Web of Science ®Google Scholar