The synthetic polyphenol tert-butyl-bisphenol inhibits myoglobin-induced dysfunction in cultured kidney epithelial cells

References

• Kim GH, Oh KH, Yoon JW, Koo JW, Kim HJ, Chae DW, Noh JW, Kim JH, Park YK. Impact of burn size and initial serum albumin level on acute renal failure occurring in major burn. Am J Nephrol 2003;23:55–60.
   PubMed Web of Science ®Google Scholar
• Mustonen KM, Vuola J. Acute renal failure in intensive care burn patients (ARF in burn patients). J Burn Care Res 2008;29:227–237.
   PubMed Web of Science ®Google Scholar
• Holm C, Horbrand F, von Donnersmarck GH, Muhlbauer W. Acute renal failure in severely burned patients. Burns 1999; 25:171–178.
   PubMed Web of Science ®Google Scholar
• Vertel RM, Knochel JP. Nonoliguric acute renal failure. Jama 1967;200:598–602.
   PubMed Web of Science ®Google Scholar
• Davies DM, Pusey CD, Rainford DJ, Brown JM, Bennett JP. Acute renal failure in burns. Scand J Plast Reconstr Surg 1979;13:189–192.
   PubMed Web of Science ®Google Scholar
• Chrysopoulo MT, Jeschke MG, Dziewulski P, Barrow RE, Herndon DN. Acute renal dysfunction in severely burned adults. J Trauma 1999;46:141–144.
   PubMed Web of Science ®Google Scholar
• Moore KP, Holt SG, Patel RP, Svistunenko DA, Zackert W, Goodier D, Reeder BJ, Clozel M, Anand R, Cooper CE, Morrow JD, Wilson MT, Darley-Usmar V, Roberts LJ 2nd. A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure. J Biol Chem 1998;273:31731–31737.
   PubMed Web of Science ®Google Scholar
• Reeder BJ, Svistunenko DA, Cooper CE, Wilson MT. The radical and redox chemistry of myoglobin and hemoglobin: from in vitro studies to human pathology. Antioxid Redox Signal 2004;6:954–966.
   PubMed Web of Science ®Google Scholar
• Reeder BJ, Sharpe MA, Kay AD, Kerr M, Moore K, Wilson MT. Toxicity of myoglobin and haemoglobin: oxidative stress in patients with rhabdomyolysis and subarachnoid haemorrhage. Biochem Soc Trans 2002;30:745–748.
   PubMed Web of Science ®Google Scholar
• Vetterlein F, Hoffmann F, Pedina J, Neckel M, Schmidt G. Disturbances in renal microcirculation induced by myoglobin and hemorrhagic hypotension in anesthetized rat. Am J Physiol 1995;268:839–846.
   Google Scholar
• Zager RA. Rhabdomyolysis and myohemoglobinuric acute renal failure. Kidney Int 1996;49:314–326.
   PubMed Web of Science ®Google Scholar
• Witting PK, Mauk AG. Reaction of human myoglobin and H2O2. Electron transfer between tyrosine 103 phenoxyl radical and cysteine 110 yields a protein-thiyl radical. J Biol Chem 2001;276:16540–16547.
   PubMed Web of Science ®Google Scholar
• Holt S, Reeder B, Wilson M, Harvey S, Morrow JD, Roberts LJ, 2nd, Moore K. Increased lipid peroxidation in patients with rhabdomyolysis. Lancet 1999;353:1241.
   PubMed Web of Science ®Google Scholar
• Rayner BS, Wu BJ, Raftery M, Stocker R, Witting PK. Human S-nitroso oxymyoglobin is a store of vasoactive nitric oxide. J Biol Chem 2005;280:9985–9993.
   PubMed Web of Science ®Google Scholar
• Andriambeloson E, Witting PK. Chemical regulation of nitric oxide: a role for intracellular myoglobin? Redox Rep 2002;7: 131–136.
   PubMed Web of Science ®Google Scholar
• Rayner BS, Stocker R, Lay PA, Witting PK. Regio- and stereo-chemical oxidation of linoleic acid by human myoglobin and hydrogen peroxide: Tyr(103) affects rate and product distribution. Biochem J 2004;381:365–372.
   PubMed Web of Science ®Google Scholar
• D'Agnillo F, Alayash AI. A role for the myoglobin redox cycle in the induction of endothelial cell apoptosis. Free Radic Biol Med 2002;33:1153–1164.
   PubMed Web of Science ®Google Scholar
• Reeder BJ, Svistunenko DA, Sharpe MA, Wilson MT. Characteristics and mechanism of formation of peroxide-induced heme to protein cross-linking in myoglobin. Biochemistry 2002;41:367–375.
   PubMed Web of Science ®Google Scholar
• Parry SN, Ellis N, Li Z, Maitz P, Witting PK. Myoglobin induces oxidative stress and decreases endocytosis and monolayer permissiveness in cultured kidney epithelial cells without affecting viability. Kidney Blood Press Res 2008; 31:16–28.
   PubMed Web of Science ®Google Scholar
• Himmelfarb J, McMonagle E, Freedman S, Klenzak J, McMenamin E, Le P, Pupim LB, Ikizler TA, The PICARD Group. Oxidative stress is increased in Critically Ill Patients with Acute Renal Failure. J Am Soc Nephrol 2004;15:2449–2456.
   PubMed Web of Science ®Google Scholar
• Vazhiri ND. Causal link between oxidative stress, inflammation, and hypertension. IJKD 2008;2:1–10.
   Google Scholar
• Kim SH, Chang JW, Kim SB, Park SK, Park JS, Lee SK. Myoglobin induces vascular cell adhesion molecule-1 expression through c-Src kinase-activator protein-1/nuclear factor-kappaB pathways. Nephron Exp Nephrol 2009;114:e48–e60.
   Google Scholar
• Witting P, Pettersson K, Ostlund-Lindqvist AM, Westerlund C, Wagberg M, Stocker R. Dissociation of atherogenesis from aortic accumulation of lipid hydro(pero)xides in Watanabe heritable hyperlipidemic rabbits. J Clin Invest 1999;104: 213–220.
   PubMed Web of Science ®Google Scholar
• Witting PK, Pettersson K, Ostlund-Lindqvist AM, Westerlund C, Eriksson AW, Stocker R. Inhibition by a coantioxidant of aortic lipoprotein lipid peroxidation and atherosclerosis in apolipoprotein E and low density lipoprotein receptor gene double knockout mice. Faseb J 1999;13:667–675.
   PubMed Web of Science ®Google Scholar
• Rayner BS, Duong TT, Myers SJ, Witting PK. Protective effect of a synthetic anti-oxidant on neuronal cell apoptosis resulting from experimental hypoxia re-oxygenation injury. J Neurochem 2006;97:211–221.
   PubMed Web of Science ®Google Scholar
• Koopman G, Reutelingsperger CP, Kuijten GA, Keehnen RM, Pals ST, van Oers M. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 1994;84:1415–1420.
   PubMed Web of Science ®Google Scholar
• Duong TT, Antao S, Ellis NA, Myers SJ, Witting PK. Supplementation with a synthetic polyphenol limits oxidative stress and enhances neuronal cell viability in response to hypoxia-re-oxygenation injury. Brain Res 2008;1219:8–18.
   PubMed Web of Science ®Google Scholar
• Ahmed H, Schott EJ, Gauthier JD, Vasta GR. Superoxide dismutases from the oyster parasite Perkinsus marinus: purification, biochemical characterization, and development of a plate microassay for activity. Anal Biochem 2003;318: 132–141.
   PubMed Web of Science ®Google Scholar
• Apodaca G, Bomsel M, Lindstedt R, Engel J, Frank D, Mostov KE, Wiener-Kronish J. Characterization of Pseudomonas aeruginosa-induced MDCK cell injury: glycosylation-defective host cells are resistant to bacterial killing. Infect Immun 1995;63:1541–1551.
   PubMed Web of Science ®Google Scholar
• Leo A, Hansch C, Elkins D. Partition coefficients and their uses. Chem Rev 1971;71:525–616.
   Web of Science ®Google Scholar
• Buettner GR. The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate. Arch Biochem Biophys 1993;300:535–543.
   PubMed Web of Science ®Google Scholar
• Hack B, Witting PK, Rayner BS, Stocker R, Headrick JP. Oxidant stress and damage in post-ischemic mouse hearts: effects of adenosine. Mol Cell Biochem 2006;287:165–175.
   PubMed Web of Science ®Google Scholar
• Von Bonsdorff CH, Fuller SD, Simons K. Apical and basolateral endocytosis in Madin-Darby canine kidney (MDCK) cells grown on nitrocellulose filters. Embo J 1985;4:2781–2792.
   PubMed Web of Science ®Google Scholar
• Hurley BP, Jacewicz M, Thorpe CM, Lincicome LL, King AJ, Keusch GT, Acheson DW. Shiga toxins 1 and 2 translocate differently across polarized intestinal epithelial cells. Infect Immun 1999;67:6670–6677.
   PubMed Web of Science ®Google Scholar
• Malorni W, Testa U, Rainaldi G, Tritarelli E, Peschle C. Oxidative stress leads to a rapid alteration of transferrin receptor intravesicular trafficking. Exp Cell Res 1998;241:102–116.
   PubMed Web of Science ®Google Scholar
• Halliwell B. Antioxidant defence mechanisms: from the beginning to the end (of the beginning). Free Rad Res 1999;31:261–272.
   PubMed Web of Science ®Google Scholar
• Malorni W, Iosi F, Santini MT, Testa U. Menadione-induced oxidative stress leads to a rapid down-modulation of transferrin receptor recycling. J Cell Sci 1993;106:309–318.
   PubMed Web of Science ®Google Scholar
• Cereijido M, Valdes J, Shoshani L, Contreras RG. Role of tight junctions in establishing and maintaining cell polarity. Ann Rev Physiol 1998;60:161–177.
   PubMed Web of Science ®Google Scholar
• Alcazar JM, Caramelo CA, Alegre ER, Abad J. Ischaemic renal injury. Curr Opin Nephrol Hypertens 1997;6:157–165.
   PubMed Web of Science ®Google Scholar
• Rabelink TJ, Wijewickrama DC, de Koning EJ. Peritubular endothelium: the Achilles heel of the kidney? Kidney Int 2007;72:926–930.
   PubMed Web of Science ®Google Scholar
• Zoccali C. The endothelium as a target in renal diseases. J Nephrol 2007;20:39–44.
   PubMed Web of Science ®Google Scholar
• Thomas SR, Witting PK, Drummond GR. Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities. Antioxid Redox Signal. 2008; 10:1713–1765.
   PubMed Web of Science ®Google Scholar
• Witting PK, Rayner BS, Wu BJ, Ellis NA, Stocker R. Hydrogen peroxide promotes endothelial dysfunction by stimulating multiple sources of superoxide anion radical production and decreasing nitric oxide bioavailability. Cell Physiol Biochem 2007;20:255–268.
   PubMed Web of Science ®Google Scholar
• Witting P, Stocker R. Ascorbic acid as an antioxidant in athersclerosis. May J, Hasard A, Smirnoff N. Vitamin C: Its functions and biochemistry in animals and plants. Oxford: Bios Scientific Publishers; 2004. 261–290.
   Google Scholar
• Friebe A, Schultz G, Koesling D. Sensitizing soluble guanylyl cyclase to become a highly CO-sensitive enzyme. Embo J 1996;15:6863–6868.
   PubMed Web of Science ®Google Scholar
• Kirkby KA, Adin CA. Products of heme oxygenase and their potential therapeutic applications. Am J Physiol Renal Physiol 2006;290:563–571.
   PubMed Web of Science ®Google Scholar
• Gonzalez-Michaca L, Farrugia G, Croatt AJ, Alam J, Nath KA. Heme: a determinant of life and death in renal tubular epithelial cells. Am J Physiol Renal Physiol 2004; 286:370–377.
   Web of Science ®Google Scholar
• Tian N, Moore RS, Braddy S, Rose RA, Gu JW, Hughson MD, Manning RD Jr. Interactions between oxidative stress and inflammation in salt-sensitive hypertension. Am J Physiol Heart Circ Physiol 2007;293:H3388–H3395.
   PubMed Web of Science ®Google Scholar
• Rodríguez-Iturbe B, Vaziri ND, Herrera-Acosta J, Johnson RJ. Oxidative stress, renal infiltration of immune cells, and salt-sensitive hypertension: all for one and one for all. Am J Physiol Renal Physiol 2004;286:F606–F616.
   PubMed Web of Science ®Google Scholar
• Saban MR, Hellmich H, Nguyen N, Winston J, Hammond TG, Saban R. Time course of LPS-induced gene expression in a mouse model of genitourinary inflammation. Physiol Genomics 2001;5:147–160.
   PubMed Web of Science ®Google Scholar
• Ho AWY, Wong CK, Lam CWK. Tumor necrosis factor-a up-regulates the expression of CCL2 and adhesion molecules of human proximal tubular epithelial cells through MAPK signaling pathways. Immunobiology 2008;213:533–544.
   PubMed Web of Science ®Google Scholar
• Hisamura F, Kojima-Yuasa A, Huang X, Kennedy DO, Matsui-Yuasa I. Synergistic effect of green tea polyphenols on their protection against FK506-induced cytotoxicity in renal cells. Am J Chin Med 2008;36:615–624.
   PubMed Web of Science ®Google Scholar
• Karhumaki P, Tiitinen SL, Turpeinen H, Parkkinen J. Inhibition of ERK1/2 activation by phenolic antioxidants protects kidney tubular cells during cold storage. Transplantation 2007;83:948–953.
   PubMed Web of Science ®Google Scholar
• Chander V, Chopra K. Protective effect of resveratrol, a polyphenolic phytoalexin on glycerol-induced acute renal failure in rat kidney. Ren Fail 2006;28:161–169.
   PubMed Web of Science ®Google Scholar
• Fernández-Fúnez A, Polo FJ, Broseta L, Valer J, Zafrilla L. Effects of N-acetylcysteine on myoglobinuric-acute renal failure in rats. Ren Fail 2002;24:725–733.
   PubMed Web of Science ®Google Scholar
• Vlahović P, Cvetković T, Savić V, Stefanović V. Dietary curcumin does not protect kidney in glycerol-induced acute renal failure. Food Chem Toxicol 2007;45:1777–1782.
   PubMed Web of Science ®Google Scholar
• Brown CV, Rhee P, Chan L, Evans K, Demetriades D, Velmahos GC. Preventing renal failure in patients with rhabdomyolysis: do bicarbonate and mannitol make a difference? J Trauma 2004;56:1191–1196.
   PubMedGoogle Scholar
• Witting PK, Westerlund C, Stocker R. A rapid and simple screening test for potential inhibitors of tocopherol-mediated peroxidation of LDL lipids. J Lipid Res 1996;37:853–867.
   PubMed Web of Science ®Google Scholar
• Wu BJ, Kathir K, Witting PK, Beck K, Choy K, Li C, Croft KD, Mori TA, Tanous D, Adams MR, Lau AK, Stocker R. Antioxidants protect from atherosclerosis by a heme oxygenase-1 pathway that is independent of free radical scavenging. J Exp Med 2006;203:1117–1127.
   PubMed Web of Science ®Google Scholar