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Original Article

Contrasting Cytotoxic Mechanisms Of Similar Antitumour Diaziridinylbenzoquinones

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Pages 231-239 | Received 08 Aug 1989, Accepted 09 Sep 1989, Published online: 07 Jul 2009

References

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  • Szmigiero L., Kohn K. W. Mechanisms of DNA strand breakage and interstrand cross-linking by diaziridinylbenzoquinone (Diaziquone) in isolated nuclei from human cells. Cancer Res. 1984; 44: 4453–4457
  • Szmigiero L., Erickson L. C., Ewig R. A., Kohn K. W. DNA strand scission and cross-linking by diaziridinylbenzoquinone (Diaziquone) in human cells and relation to cell killing. Cancer Res. 1984; 44: 4447–4452
  • Dzielendziak A., Butler J. 1,4-benzoquinones: New diaziridinyl analogues and improved methods of synthesis. Synthesis 1989; 643–646
  • Butler J., Hoey B. M., Ward T. M. The alkylation of DNA in vitro by 2,5-bis(2-hydroxyethylamino)-3,6-diaziridinyl-l,4-benzoquinone (BZQ) - I. Biochem. Pharmcicol. 1989; 38: 923–927
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  • Dzielendziak A., Butler J., Hoey B. M., Lea J. S., Ward T. H. A comparison of the structural and cytotoxic activity of novel AZQ analogues. 1989, submitted

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