Multicomponent Investigations of the Hydrogen Peroxide- and Hydroxyl Radical-Scavenging Antioxidant Capacities of Biofluids: The Roles of Endogenous Pyruvate and Lactate Relevance to Inflammatory Joint Diseases

References

• Halliwell B., Gutteridge J. M. C., Blake D. R. Metal ion and oxygen radical reactions in human inflammatory joint disease. Philosophical Transactions of the Royal Society London 1985; B311: 659–671
   Google Scholar
• Merry P., Grootveld M., Blake D. R. Free Radicals and hypoxic-reperfusion injury. ARC Topical Review, T. Scott, M. Jayson, J. Moll, D. Isenberg, 1990; No. 15
   Google Scholar
• Grootveld M., Nazhat N. B., Patel I. Y., Blake D. R. Free radical biochemistry and rheumatoid arthritis. Current Medical Literature-Rheunmatology 1992; 11(2)35–42
   Google Scholar
• Rowley D. A., Gutteridge J. M. C., Blake D. R., Farr M., Halliwell 8. Lipid peroxidation in rheumatoid arthritis: thiobarbituric acid reactive material and catalytic iron salts in synovial fluid from rheumatoid patients. Clinical Science 1984; 66: 691–695
   Google Scholar
• Lunec J., Brailsford S., Hewitt S. D., Morris C. J., Blake D. R. Free radicals: are they possible mediators of IgG denaturation and immune complex formation in RA. Free Radicals and Arthritic Diseases, A. J. C. Swaak, J. F. Koster, Eurage, Rijswijk 1986; 3–11
   Google Scholar
• Merry P., Grootveld M., Lunec J., Blake D. R. Oxidative damage to lipids within the inflamed human joint provides evidence of radical-mediated hypoxicreperfusion injury. American Journal of Clinical Nutrition 1991; 53: 362S-369S
   PubMedGoogle Scholar
• Riddles P. W., Blakely R. L., Zerner B. Ellman's reagent: 5,5′-dithiobis (2-nitrobenzoic acid)—a re-examination. Analytical Biochemistry 1979; 94: 75–81
   PubMedGoogle Scholar
• Blake D. R., Merry P., Unsworth J., Kidd B., Outhwaite J. M., Ballard R., Morris C. J., Gray L., Lunec J. Hypoxic-reperfusion injury in the inflamed human joint. Lancet 1989; (i): 289–293
   Google Scholar
• Henderson E. 8., Grootveld M., Blake D. R. Origins of free radical mediated damage in the inflamed joint. European Journal of Rheumatology and Inflammation 1991; 11(1)27–35
   Google Scholar
• Henderson E. B., Grootveld M., Farrell A. J., Smith E. C., Blake D. R. A pathological role for damaged hyaluronan in synovitis. Annals of the Rheumatic Diseases 1991; 50: 196–200
   PubMedGoogle Scholar
• Allen R. E., Blake D. R., Nazhat N. B., Jones P. Superoxide radical generation by inflamed human synovium after hypoxia. Lancet 1989; (ii): 282–283
   Google Scholar
• Grootveld M., Henderson E. B., Farrell A., Blake D. R., Parkes H. G., Haycock P. Oxidative damage to hyaluronate and glucose in synovial fluid during exercise of the inflamed rheumatoid joint: Detection of abnormal low-molecular-mass metabolites by proton NMR spectroscopy. Biochemical Journal 1991; 273(2)459–467
   Google Scholar
• Reitzer L. J., Wice B. M., Kennell D. Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells. Journal of Biological Chemistry 1979; 254: 2669–2676
   Google Scholar
• Baker M. S., Feigan J., Lowther J. A. The mechanisms of chondrocyte hydrogen peroxide damage. Depletion of intracellular ATP due to suppression of glycolysis caused by oxidation of glyceraldehyde-3-phosphate dehydrogenase. Journal of Rheumatology 1989; 16: 7–14
   PubMedGoogle Scholar
• Spragg R. G., Hinshaw D. B., Hyslop P. A., Schraufstatter I. U., Cochrane C. G. Alterations in adenosine triphosphate and energy charge in cultured endothelial and P388D cells after oxidant injury. Journal of Clinical Investigation 1985; 76: 1471–1476
   Google Scholar
• Hyslop P. A., Hinshaw D. B., Halsey W. A., Schraufstatter I. U., Sauerheber R. S., Spragg R. G., Jackson J. H., Cochrane C. G. Mechanisms of oxidant mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation as major intracellular targets inactivated by hydrogen peroxide. Journal of Biological Chemistry 1988; 263: 1665–1671
   Google Scholar
• Bax B. E., Alam A. S. M. T., Banerji B., Bax C. M. R., Beviss P. J. R., Stevens C. R., Moonga B. S., Blake D. R., Zaidi M. Stimulation of osteoclastic bone resorption by hydrogen peroxide (H2O2). Biochem. Biophys. Res. Commun 1992; 183: 1153–1158
   Google Scholar
• Neuman R. E., McCoy T. A. Growth-promoting properties of pyruvate, oxalacetate, and α-ketoglu tarate for isolated Walter Carcinoma 256 cells. Proceedings of the Society for Experimental Biology and Medicine 1958; 98: 303–306
   Google Scholar
• Herzenberg L. A., Roosa R. A. Nutritional requirements for growth of a mouse lymphoma in cell culture. Experimental Cell Research 1960; 21: 430–438
   Google Scholar
• Moser H. Modern approaches to the study of mammalian cells in culture. Experientia Basel 1960; 16: 385–432
   Google Scholar
• Neuman R. E., Tytell A. A. Partial replacement of serum and embryo extract requirements for growth of avian cell cultures. Proceedings of the Society for Experimental Biology and Medicine 1961; 106: 857–862
   Google Scholar
• Wasilenko W. J., Marchock C. Pyruvate regulation of growth and differentiation in primary cultures of rat tracheal epithelial cells. Experimental Cell Research 1984; 55: 507–517
   Google Scholar
• McKeehan W. L., McKeehan K. A. Oxycarboxylic acids, pyridine-nucleotide-linked oxidoreductases and serum factors in regulation of cell proliferation. Journal of Cell Physiology 1979; 101: 9–16
   PubMedGoogle Scholar
• McKeehan W. L., McKeehan K. A. Serum factors modify the cellular requirement for Ca2+, K+, Mg2+, phosphate ions, and 2-oxocarboxylic acids for multiplication of normal human fibroblasts. Proceedings of the National Academy of Sciences of the U.S.A 1980; 77(6)3417–3420
   Google Scholar
• Ellem K. A. O., Kay G. F. The nature of conditioning nutrients for human malignant melanoma cultures. Journal of Cell Science 1983; 62: 249–266
   Google Scholar
• Selak I., Skaper S. D., Varon S. J. Pyruvate participation in the low molecular weight tropic activity for central nervous system neurons in glia-conditioned media. Journal of Neuroscience 1985; 5(1: 23–28
   Google Scholar
• Higuchi K. Studies on the nutrition and metabolism of animal cells in serum-free media. Journal of Infectious Diseases 1963; 112: 213–220
   Google Scholar
• Halestrap A. P., Scott R. D., Thomas A. P. Mitochondrial pyruvate transport and its hormonal regulation. International Journal of Biochemistry 1980; 11: 97–105
   PubMedGoogle Scholar
• Salahudeen A. K., Clark E. C., Nath K. A. Hydrogen peroxide-induced renal injury. A protective role for pyruvate in vitro and in vivo Journal of Clinical Investigation 1991; 88: 1886–1893
   Google Scholar
• Murer H., Burkhardt G. Membrane transport of anions across epithelia of mammalian small intestine and kidney proximal tubule. Reviews in Physiology, Biochemistry and Pharmacology 1983; 96: l-51
   Google Scholar
• Bock J. L. Analysis of serum by high field proton nuclear magnetic resonance. Clinical Chemistry 1982; 28: 1873–1877
   Google Scholar
• Nicholson J. K., Buckingham M. J., Sadler P. J. High resolution 1H NMR studies of vertebrate blood and plasma. Biochemical Journal 1983; 211: 605–615
   Google Scholar
• Nicholson J. K., O'Flynn M. P., Sadler P. J., MacLeod A. F., Juul S. M., Sönksen P. J. Protonnuclear-magnetic-resonance studies of serum, plasma and urine from fasting normal and diabetic subjects. Biochemical Journal 1984; 217: 365–375
   Google Scholar
• Grootveld M., Bell J., Halliwell B., Aruoma O. I., Bomford A., Sadler P. J. Non-transferrin-bound iron in plasma from patients with idiopathic haemachromatosis. Characterisation by high performance liquid chromatography and nuclear magnetic resonance. Journal of Biological Chemistry 1989; 264: 4417–4422
   Google Scholar
• Grootveld M., Herz H., Haywood R., Hawkes G. E., Naughton D., Perera A., Knappitt J., Blake D. R., Claxson A. W. D. Multi component analysis of radio lytic products in human body fluids using high field proton (1H) nuclear magnetic resonance (NMR) spectroscopy. Radiation Physics and Chemistry 1994; 43(5: 445–453
   Google Scholar
• James M. J., Cleland L. G., Rofe A. M., Leslie A. L. Intra-articular pressure and the relationship between synovial perfusion and metabolic demand. Journal of Rheumatology 1990; 17: 521–527
   Google Scholar
• Bell J. D., Brown J. C. C., Kubal G., Sadler P. J. NMR-invisible lactate in blood plasma. FEBS Letters 1988; 235: 81–86
   Google Scholar
• Holleman M. A. F. Notice sur l'action de l'eau oxygénéé sur les acides acétoniques et sur les dicétones 1.2. Recl. Trav. Chim. Pays-bas Belg 1904; 23: 169–171
   Google Scholar
• Bunton C. A. Oxidation of a-diketones and a-ketoacids by hydrogen peroxide. Nature London 1949; 163: 444
   PubMed Web of Science ®Google Scholar
• Melzer E., Schmidt H. Carbon isotope effects on the decarboxylation of carboxylic acids. Biochemical Journal 1988; 252: 913–915
   Google Scholar
• Anbar M., Neta P. A compilation of bi-molecular rate constants for the reaction of hydrated electrons, hydrogen atoms and hydroxyl radicals with inorganic and organic compounds in aqueous solutions. International Journal of Applied Radiation and Isotopes 1967; 18: 493–497
   Google Scholar
• Lunec J., Blake D. R. The determination of dehydroascorbic acid and ascorbic acid in the serum and synovial fluid of patients with rheumatoid arthritis. Free Radical Research Communications 1985; 1: 31–39
   Google Scholar
• Furnival C., May P. M., Williams D. R. Models of low-molecular-weight copper (II) complexing equilibria in relation to rheumatoid arthritis. Trace Elements in the Pathogenesis and Treatment of Inflammation, K. D. Rainsford, K. Brune, M. W. Whitehouse. Birkhäuser Verlag, Basel, Boston 1981; 241–257
   Google Scholar
• Ferrair R., Ceconi C., Curello S., Cargoni A., Medici D. Oxygen free radicals and reperfusion injury: the effect of ischaemia and reperfusion on the cellular ability to neutralise oxygen. Journal of Molecular and Cellular Cardiology 1986; 18: 67–69
   Google Scholar
• Gutteridge J. M. C. G. Bleomycin-detectable iron in knee-joint synovial fluid from arthritic patients and its relationship to the extracellular activities of caeuruloplasmin, transferrin and lactoferrin. Biochemical Journal 1987; 245: 415–421
   Google Scholar
• Parkes H. G., Allen R. E., Furst A., Blake D. R., Grootveld M. Speciation of non-transferrin-bound iron in synovial fluid from patients with rheumatoid arthritis by proton nuclear magnetic resonance spectroscopy. Journal of Pharmaceutical and Biomedical Analysis 1991; 9(1: 29–32
   Google Scholar
• Garrison W. M. The radiation chemistry of amino acids, peptides and proteins in relation to the radiation sterilisation of high-protein foods. Radiation Effects 1981; 54: 29–40
   Google Scholar
• O'Donnell-Tormy J., Nathan C. F., Lanks D., DeBoer C. J., De La Harpe J. Secretion of pyruvate. An antioxidant defense of mammalian cells. Journal of Experimental Medicine 1987; 165: 500–514
   Google Scholar
• Marx G., Chevion M. Site-specific modification of albumin by free radicals. Reaction with copper (II) and ascorbate. Biochemical Journal 1986; 236: 397–400
   PubMedGoogle Scholar
• Lau S., Kruck T. P. A., Sarkar B. A peptide molecule mimicking the copper(II) transport site of human serum albumin. The Journal of Biological Chemistry 1974; 249(18: 5878–5884
   Google Scholar
• Yoshino S., Blake D. R., Hewitt S., Morris C., Bacon P. A. Effect of blood on the activity and persistence of antigen induced inflammation in the rat air pouch. Annals of the Rheumatic Diseases 1985; 44: 485–490
   Google Scholar