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Original Article

Ionizing Radiation Induces, via Generation of Reactive Oxygen Intermediates, Intercellular Adhesion Molecule-1 (ICAM-1) Gene Transcription and NFκB-like Binding Activity in the ICAM-1 Transcriptional Regulatory Region

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Pages 127-142 | Received 16 Jan 1997, Published online: 07 Jul 2009

References

  • Springer T. Adhesion receptors of the immune system. Nature 1990; 346: 425–434
  • McCourt P. A. G., Forsberg N., Gustafson S. Intercellular adhesion molecule-1 is a cell surface receptor for hyaluronan. Journal of Biological Chemistry 1994; 269: 30081–30084
  • Makgoba M. W., Sanders M. E., Luce G. E., Dustin M. L., Springer T. A., Clark E. A., Mannoni P., Shaw S. ICAM-1 a ligand for LFA-1-dependent adhesion of B, T and myeloid cells. Nature 1988; 331: 86–88
  • Staunton D. E., Marlin S. D., Stratowa C., Dustin M. L., Springer T. A. Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families. Cell 1988; 52: 925–933
  • Dustin M. L., Rothlein R., Bhan A. K., Dinarello C. A., Springer T. A. Induction by IL 1 and inter-feron-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). Journal of Immunology 1986; 137: 245–254
  • Pober J. S., Gimbrone M. A., Jr., Lapierre L. A., Mendrick D. L., Fiers W., Rothlein R., Springer T. A. Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon. Journal of Immunology 1986; 137: 1893–1896
  • Rokein R., Dustin M. L., Marlin S. D., Springer T. A. A human intercellular adhesion molecule (ICAM-I) distinct from LFA-1. Journal of Immunology 1986; 137: 1270–1274
  • Norris D. A., Lyons M. B., Middleton M. H., Yohn J. J., Kashihara S. M. Ultraviolet radiation can either suppress or induce expression of intercellular adhesion molecule 1 (ICAM-1) on the surface of cultured human keratinocytes. Journal of Investigative Dermatology 1990; 95: 132–138
  • Krutmann J., Czech W., Parlow F., Trefzer U., Kapp A., Schopf E., Luger T. A. Ultraviolet radiation effects on human keratinocyte ICAM-l expression: UV-induced inhibition of cytokine-induced ICAM-1 mRNA expression is transient, differentially restored for IFNy versus TNFa, and followed by ICAM-1 induction via a TNFa-like pathway. Journal of Investigative Dermatology 1992; 98: 923–928
  • Heckmann M., Eberlein-König B., Wollenberg A., Przybilla B., Plewig G. Ultraviolet-A radiation induces adhesion molecule expression on human dermal microvascular endothelial cells. British Journal of Dermatology 1994; 131: 311–318
  • Behrends U., Peter R. U., Hintermeier-Knabe R., EilZner G., Holler E., Bornkamm G. W., Caughman S. W., Degitz K. Ionizing radiation induces human intercellular adhesion molecule-1. in vitro. Journal of Investigative Dermatology 1994; 103: 726–730
  • Ohh M., Takei F. Interferon-gamma- and phorbol myristate acetate-responsive elements involved in intercellular adhesion molecule-1 mRNA stabilization. Journal of Biological Chemistry 1994; 269: 30117–30120
  • Stade B. G., Messer G., Riethmuller G., Johnson J. P. Structural characteristics of the 5′ region of the human ICAM-1 gene. Immunobiology 1990; 182: 79–87
  • Degitz K., Li L. J., Caughman S. W. Cloning and characterization of the 5′-transcriptional regulatory region of the human intercellular adhesion molecule 1 gene. Journal of Biological Chemistry 1991; 266: 14024–14030
  • Voraberger G., Schäfer R., Stratowa C. Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5′-regulatory region. Induction by cytokines and phorbol ester. Journal of Immunology 1991; 147: 2777–2786
  • Wawryk S. O., Cockerill P. N., Wicks I. P., Boyd A. W. Isolation and characterization of the promoter region of the human intercellular adhesion molecule-1 gene. International Immunology 1991; 3: 83–93
  • Ledebur H. C., Parks T. P. Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells. Essential roles of a variant NF-kappa B site and p65 homodimers. Journal of Biological Chemistry 1995; 270: 933–943
  • Ballantyne C. M., Sligh J. J., Dai X. Y., Beaudet A. L. Characterization of the murine Icam-l gene. Genomics 1992; 14: 1076–80
  • Van de Stolpe A., Caldenhoven E., Stade B. G., Koendermann L., Raaijmakers J. A. M., Johnson J. P., Van der Saag P. T. 12-Tetradecanoylphorbol-13-acetate- and tumor necrosis factor alpha-mediated induction of intercellular adhesion molecule-1 is inhibited by dexamethasone. Journal of Biological Chemistry 1994; 289: 6185–6192
  • Hou J., Baichwal V., Cao Z. Regulatory elements and transcription factors controlling basal and cytokine-induced expression of the gene encoding intercellular adhesion molecule 1. Proceedings of the National Academy of sciences USA 1994; 91: 11641–11645
  • Mueller S., Kammerbauer C., Simons U., Shibagaki N., Li L. J., Caughman S. W., Degitz K. Transcriptional regulation of intercellular adhesion mol-ecule-l: PMA-induction is mediated by NF kappa B. Journal of Investigative Dermatology 1995; 104: 970–975
  • Look D. C., Pelletier M. R., Holtzman M. J. Selective interaction of a subset of interferon-gamma response element-binding proteins with the intercellular adhesion molecule-1 (ICAM-1) gene promoter controls the pattern of expression on epithelial cells. Journal of Biological Chemistry 1994; 269: 8952–8958
  • Caldenhoven E., Coffer P., Yuan J., Van de Stolpe A., Horn F., Kruijer W., Van der Saag P. T. Stimulation of the human intercellular adhesion molecule-1 promoter by interleukin-6 and interferon-gamma involves binding of distinct factors to a palindromic response element. Journal of Biological Chemistry 1994; 269: 21146–21154
  • Cilenti L., Toniato E., Ruggiero P., Fusco C., Farina A. R., Tiberio A., Hayday A. C., Gulino A., Frati L., Martinotti S. Transcriptional modulation of the human intercellular adhesion molecule gene I (ICAM-I) by retinoic acid in melanoma cells. Experimental Cell Research 1995; 218: 263–270
  • Riley P. A. Free radicals in biology: oxidative stress and the effects of ionizing radiation. International Journal of Radiation Biology 1994; 65: 27–33
  • Boukamp P., Petrussevska R. T., Breitkreuz D., Hornung J., Markham A., Fusenig N. E. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. Journal of Cell Biology 1988; 106: 761–771
  • Sambrook J., Fritsch E. F., Maniatis 7. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor 1989
  • Ausubel F. M., Brent R., Kingston R. E., Moore D. D., Seidman J. G., Smith J. A., Struhl K. Current protocols in molecular biology. J. Wiley & Sons, New York 1989
  • Brach M. A., Hass R., Sherman M. L., Gunji H., Weichselbaum R., Kufe D. Ionizing radiation induces expression and binding activity of the nuclear factor kappa B. Journal of Clinical Investigation 1991; 88: 691–695
  • Baeuerle P. A., Henkel T. Function and activation of NF-kappaB in the immune system. Annual Reviews of Immunology 1994; 12: 141–179
  • Thanos D., Maniatis T. NFkB: a lesson in family values. Cell 1995; 80: 529–532
  • Kunsch C., Ruben S. M., Rosen C. A. Selection of optimal rB/Rel DNA-binding motifs: interaction of both subunits of NF-κB with DNA is required for transcriptional activation. Molecular and Cellular Biology 1992; 12: 4412–4421
  • Jahnke A., Johnson J. P. Synergistic activation of intercellular adhesion molecule 1 (ICAM-I) by TNF-alpha and IFN-gamma is mediated by p65/p50 and p65/c-Rel and interferon-responsive factor Stat1 alpha (p91) that can be activated by both IFN-gamma and IFN-alpha. Febs Letters 1994; 354: 220–226
  • Mohan N., Meltz M. L. Induction of nuclear factor kappaB after low-dose ionizing radiation involves a reactive oxygen intermediate signaling pathway. Radiation Research 1994; 140: 97–104
  • Schreck R., Rieber P., Baeuerle P. A. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HN-I. EMBO Journal 1991; 10: 2247–2258
  • Schreck R., Meier B., Männel D. N., Dröge W., Baeuerle P. A. Dithiocarbamates as potent inhibitors of nuclear factor kappaB activation in intact cells. Journal of Experimental Medicine 1992; 175: 1181–1194
  • Ziegler H. H., Fingerle G., Strobel M., Schraut W., Stelter F., Schutt C., Passlick B., Pforte A. The novel subset of CD14+/CD16+ blood monocytes exhibits features of tissue macrophages. European Journal of Immunology 1993; 23: 2053–2058
  • Meyer M., Schreck R., Baeuerle P. A. H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO Journal 1993; 12: 2005–2015
  • Ikeda M., Schroeder K. K., Mosher L. B., Woods C. W., Akeson A. L. Suppressive effect of antioxidants on intercellular adhesion molecule-1 (ICAM-1) expression in human epidermal keratinocytes. Journal of Investigative Dermatology 1994; 103: 791–796
  • Kawai M., Nishikomori R., Jung E. Y., Tai G., Yamanaka C., Mayumi M., Heike T. Pyrrolidine dithiocarbamate inhibits intercellular adhesion molecule-1 biosynthesis induced by cytokines in human fibroblasts. Journal of Immunology 1995; 154: 2333–2341
  • Marui N., Offermann M. K., Swerlick R., Kunsch C., Rosen C. A., Ahmad M., Alexander R. W., Medford R. M. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. Journal of Clinical Investigation 1993; 92: 1866–1874
  • Munoz C., Castellanos M. C., Alfranca A., Vara A., Esteban M. A., Redondo J. M., Delandazuri M. O. Transcriptional up regulation of intracellular adhesion molecule 1 in human endothelial cells by the antioxidant pyrrolidine dithiocarbamate involves the activation of activating protein 1. Journal of Immunology 1996; 157: 3587–3597
  • Cornelius L. A., Taylor J. T., Degitz K., Li L. J., Lawley T. J., Caughman S. W. A 5′ portion of the TCAM-1 gene confers tissue-specific differential expression levels and cytokine responsiveness. Journal of Investigative Dermatology 1993; 100: 753–758
  • Jahnke A., Van S. A. D., Caldenhoven E., Johnson J. P. Constitutive expression of human intercellular adhesion molecule-l (ICAM-1) is regulated by differentially active enhancing and silencing elements. European Journal of Biochemistry 1995; 228: 439–446
  • Hallahan D. E., Gius D., Kuchibothla J., Sukhatme V., Kufe D. W., Weichselbaum R. R. Radiation signaling mediated by Jun activation following dissociation from a cell type-specific repressor. Journal of Biological Chemistry 1993; 268: 4903–4907
  • Boothman D. A., Meyers M., Fukunaga N., Lee S. W. Isolation of x-ray-inducible transcripts from radioresistant human melanoma cells. Proceedings of the National Academy of Sciences USA 1993; 90: 7200–7204
  • Krutmann J., Grewe M. Involvement of cytokines, DNA damage, and reactive oxygen intermediates in ultraviolet radiation-induced modulation of intercellular adhesion molecule-1 expression. Journal of Investigative Dermatology 1995; 105: 67S-70S
  • Sherman M. L., Datta R., Hallahan D. E., Weichselbaum R. R., Kufe D. W. Ionizing radiation regulates expression of the c-jun protooncogene. Proceedings of the National Academy of Sciences USA 1990; 87: 5663–5666
  • Goldschmidt H., Breneman J. C., Breneman D. L. Ionizing radiation therapy in dermatology. Journal of the American Academy of Dermatology 1994; 30: 157–182
  • Harning R., Pelletier J., Lubbe K., Takei F., Merluzzi V. J. Reduction in the severity of graft-versus-host disease and increased survival in allogeneic mice by treatment with monoclonal antibodies to cell adhesion antigens LFA-1 and MALA-2. European Journal of Immunology 1991; 20: 2591–2596

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