Implantable microchip: the futuristic controlled drug delivery system

References

• Armani DK, Liu C. (2000). Microfabrication technology for polycaprolactone, a biodegradable polymer. Micro Electro Mech Sys 10:80–4
   Google Scholar
• Banerjee PS, Robinson JR. (1991). Novel drug delivery systems: an overview of their impact on clinical pharmacokinetic studies. Clin Pharma 20:1–14
   Google Scholar
• Betancourt T, Brannon-Peppas L. (2006). Micro- and nanofabrication methods in nano technological medical and pharmaceutical devices. Int J Nanomed 1:483–95
   PubMed Web of Science ®Google Scholar
• Bramstedt AK. (2005). When microchip implants do more than drug delivery: Blending, blurring, and bundling of protected health information and patient monitoring. Tech Health Care 13:193–8
   PubMedGoogle Scholar
• Brazil M. (2003). Drug delivery: biodegradable multi-drug dispenser. Nat Rev Drug Discov 2:946
   Web of Science ®Google Scholar
• Breimer DD. (1999). Future challenges for drug delivery. J Control Release 62:3–6
   PubMed Web of Science ®Google Scholar
• Bustillo JM, Howe RT, Muller RS. (1998). Surface micromachining for microelectromechanical systems. Proc IEEE 86:1552–74
   Web of Science ®Google Scholar
• Cima MJ, Langer RS, Santini JT Jr. Massachusetts Institute of Technology, assignee. (2000). Fabrication of microchip drug delivery device. US Patent US6123861, 26 Sept 2000
   Google Scholar
• Cheung R. (2012). AAAS Meeting: wireless drug delivery achieved: implanted microchip releases medication on command. Sci News 181:8
   Google Scholar
• Chien YW, Lin S. (2006). Drug delivery: controlled release (Chapter 73). In: James S, ed. Encyclopedia of pharmaceutical technology. Florida, USA: CRC Press, Taylor & Francis Group,1082–102
   Google Scholar
• Choonara YE, Pillay V, Danckwerts MP, et al. (2010). A review of implantable intravitreal drug delivery technologies for the treatment of posterior segment eye diseases. J Pharm Sci 99:2219–39
   PubMed Web of Science ®Google Scholar
• Chung AJ, Kim D, Erickson D. (2008). Electrokinetic microfluidic devices for rapid, low power drug delivery in autonomous microsystems. Lab on a Chip 8:330–8
   Google Scholar
• Daniel K, Duc HL, Cima M, Langer R. (2009). Controlled release microchips (Chapter 9). In: Youan BC, ed. Chronopharmaceutics: science and technology for biological rhythm-guided therapy and prevention of diseases. New Jersey, USA: John Wiley & Sons Inc. Publication, 187–212
   Google Scholar
• Dario P, Carrozza MC, Benvenuto A, et al. (2000). Micro-systems in biomedical Applications. Microeng J Micromech 10:235–44
   Web of Science ®Google Scholar
• Drews J. (2000). Drug discovery: a historical perspective. Science 287:1960–4
   PubMed Web of Science ®Google Scholar
• Eljarrat-Binstock E, Pe'er J, Domb AJ. (2010). New techniques for drug delivery to the posterior eye segment. Pharm Res 27:530–43
   PubMed Web of Science ®Google Scholar
• Farra R, Sheppard NF, McCabe L, et al. (2012). First-in-human testing of a wirelessly controlled drug delivery microchip. Sci Transl Med 4:1–10
   Web of Science ®Google Scholar
• Gardner P. (2006). Microfabricated nanochannel implantable drug delivery devices: trends, limitations and possibilities. Exp Opin Drug Deliv 3:479–87
   PubMedGoogle Scholar
• Ge D, Tian X, Qi R, et al. (2009). A polypyrrole-based microchip for controlled drug release. Electrochim Acta 55:271–5
   Web of Science ®Google Scholar
• Gershon D. (2012). Drug delivery goes remote. Nat Med 18:506
   Google Scholar
• Goldman P. (1982). Rate-controlled drug delivery. N Engl J Med 307:286–90
   PubMed Web of Science ®Google Scholar
• Gourley PL. (1996). Semiconductor microlasers: a new approach to cell-structure analysis. Nat Med 2:942–4
   PubMed Web of Science ®Google Scholar
• Graham-Rowe D. (2012). Wireless drug implant takes the trouble out of treatment. Nature News & Comment. doi:10.1038/nature.2012.10045. Available at: http://www.nature.com/news/wireless-drug-implant-takes-the-trouble-out-of-treatment-1.10045
   Google Scholar
• Grayson ACR, Choi IS, Tyler BM, et al. (2003). Multi-pulse drug delivery from a resorbable polymeric microchip device. Nat Mater 2:767–72
   PubMed Web of Science ®Google Scholar
• Grayson ACR, Chima JM, Langer R, et al. (2004a). A BioMEMS review: MEMS technology for physiologically integrated devices. IEEE 92:6–21
   Web of Science ®Google Scholar
• Grayson ACR, Cima MJ, Langer R. (2004b). Molecular release from a polymeric microreservoir device: influence of chemistry, polymer swelling, and loading on device performance. J Biomed Mat Res Part A 69A:502–12
   Web of Science ®Google Scholar
• Grayson ACR, Scheidt Shawgo R, Li Y, Cima MJ. (2004c). Electronic MEMS for triggered delivery. Adv Drug Deliv Rev 56:173–84
   PubMed Web of Science ®Google Scholar
• Hilt JZ, Peppas NA. (2005). Microfabricated drug delivery devices. Int J Pharma 306:15–23
   PubMed Web of Science ®Google Scholar
• Jain D, Raturi R, Jain V, et al. (2011). Recent technologies in pulsatile drug delivery systems. Biomatter 1:57–65
   PubMedGoogle Scholar
• Jonietz E. (2006). Implantable medication: programmable drug chips pass longevity milestone. MIT Tech Rev May/June:23
   Google Scholar
• Kikuchi A, Okano T. (2002). Pulsatile drug release control using hydrogels. Adv Drug Deliv Rev 54:53–77
   PubMed Web of Science ®Google Scholar
• Kim GY, Chima MJ, Tupper MM, et al. (2007). Resorbable polymer microchips releasing BCNU inhibit tumor growth in the rat 9L flank model. J Control Release 123:172–8
   PubMed Web of Science ®Google Scholar
• Kovacs GTA, Knapp TR, LipoMatriz, Inc., assignee. (1998). Implantable biosensing transponder. US Patent US5833603, 10 Nov 1998
   Google Scholar
• Kuo Y, Violante MR, Pharma Nova Inc., assignee. (2012). Implantable drug delivery device. US Patent US0059349 A1, 8 Mar 2012
   Google Scholar
• Lang W. (1996). Silicon microstructuring technology. Mat Sci Eng R Rep 17:1–55
   Web of Science ®Google Scholar
• Langer R. (1990). New methods of drug delivery. Science 249:1529–33
   Google Scholar
• Langer R, Peppas NA. (2003). Advances in biomaterials, drug delivery, and bionanotechnology. AIChE J 49:2990–3006
   Web of Science ®Google Scholar
• LaVan DA, Lynn DM, Langer R. (2002). Moving smaller in drug discovery and delivery. Nat Rev Drug Discov 1:77–84
   PubMed Web of Science ®Google Scholar
• Lee SH, Park M, Park CG, et al. (2012). Microchip for sustained drug delivery by diffusion through microchannels. AAPS PharmSciTech 13:211–17
   PubMed Web of Science ®Google Scholar
• Lesniak SM, Brem H. (2004). Targeted therapy for brain tumours. Nat Rev Drug Discov 3:499–508
   PubMed Web of Science ®Google Scholar
• Li Y, Shawgo RS, Tyler B, et al. (2004). In vivo release from a drug delivery MEMS device. J Control Release 100:211–19
   PubMed Web of Science ®Google Scholar
• Liu X, Pettway GJ, McCauley LK, et al. (2007). Pulsatile release of parathyroid hormone from an implantable delivery system. Biomaterials 28:4124–31
   PubMed Web of Science ®Google Scholar
• Maloney MJ. (2003). Proceedings of IMECE'03. 15–21 Nov 2003 ASME International Mechanical Engineering Congress, Washington, DC
   Google Scholar
• Maloney JM, Uhland SA, Polito BF, et al. (2005). Electrothermally activated microchips for implantable drug delivery and biosensing. J Control Release 109:244–55
   PubMed Web of Science ®Google Scholar
• Mansoor S, Kuppermann BD, Kenney MC. (2009). Intraocular sustained release delivery systems for triamcinolone acetonide. Pharm Res 26:770–84
   PubMed Web of Science ®Google Scholar
• Medlicott NJ, Tucker IG. (1999). Pulsatile release from subcutaneous implants. Adv Drug Deliv Rev 38:139–49
   PubMed Web of Science ®Google Scholar
• Nisar A, Afzulpurkar N, Mahaisavariya B, et al. (2008). MEMS-based micropumps in drug delivery and biomedical applications. Sensor Actuat B Chem 130:917–42
   Web of Science ®Google Scholar
• Orive G, Gascón AR, Hernández RM, et al. (2004). Techniques: new approaches to the delivery of biopharmaceuticals. Trends Pharma Sci 25:382–7
   PubMed Web of Science ®Google Scholar
• Peppas NA. (2004). Intelligent therapeutics: biomimetic systems and nanotechnology in drug delivery. Adv Drug Deliv Rev 56:1529–31
   PubMed Web of Science ®Google Scholar
• Peppas NA, Byrne ME. (2003). New biomaterials for intelligent biosensing, recognitive drug delivery and therapeutics. Bull Gattefosśe 96:23–35
   Google Scholar
• Petersen KE. (1982). Silicon as a mechanical material. Proc IEEE 70:420–57
   Web of Science ®Google Scholar
• Polla DL, Erdman AG, Robbins WP, et al. (2000). Microdevices in medicine. Ann Rev Biomed Eng 2:551–76
   PubMed Web of Science ®Google Scholar
• Putney SD, Burke PA. (1998). Improving protein therapeutics with sustained-release formulations. Nat Biotech 16:153–7
   PubMed Web of Science ®Google Scholar
• Razzacki SZ, Thwar PK, Yang M, et al. (2004). Integrated microsystems for controlled drug delivery. Adv Drug Deliv Rev 56:185–98
   PubMed Web of Science ®Google Scholar
• Receveur RAM, Linemans FW, de Rooij NF. (2007). Microsystem technologies for implantable applications. J Micromech Microeng 17:R50–80
   Google Scholar
• Sakamoto JH, Van de Ven AL, Godin B, et al. (2010). Enabling individualized therapy through nanotechnology. Pharmacol Res 62:57–89
   PubMed Web of Science ®Google Scholar
• Sant S, Tao SL, Fisher O, et al. (2012). Microfabrication technologies for oral drug delivery. Adv Drug Deliv Rev 64:496–507
   PubMed Web of Science ®Google Scholar
• Santini JT Jr, Cima MJ, Langer RS, Massachusetts Institute of Technology, assignee. (1998). Microchip drug delivery devices. US Patent US5797898 25 Aug 1998
   Google Scholar
• Santini JT Jr, Cima MJ, Langer RS. (1999). A controlled-release microchip. Nature 397:335–8
   PubMed Web of Science ®Google Scholar
• Santini JT Jr, Chima MJ, Langer RS. (2000a). Microchip as controlled drug-delivery device. Angew Chem Int Ed 39:2396–407
   PubMed Web of Science ®Google Scholar
• Santini JT Jr, Richards AC, Scheidt RA, et al. (2000b). Microchip technology in drug delivery. Ann Med 32:377–9
   PubMed Web of Science ®Google Scholar
• Santini JT Jr, Cima MJ, Langer RS, et al., MicroCHIPS Inc., assignee. (2005). Flexible microchip devices for ophthalmic and other applications. US Patent US6976982 B2, 20 Dec 2005
   Google Scholar
• Santini JT Jr, Cima MJ, Langer RS. Massachusetts Institute of Technology, assignee. (2011). Method for operating microchip reservoir devices. US Patent US7901397B2, 8 Mar 2011
   Google Scholar
• Schulz M. (1999). The end of the road for silicon? Nature 399:729–30
   Web of Science ®Google Scholar
• Shawgo RS, Richards Grayson AC, Li Y. (2002). BioMEMS for drug delivery. Mater Sci 6:329–34
   Web of Science ®Google Scholar
• Sharma S, Nijdam AJ, Sinha PM, et al. (2006). Controlled-release microchips. Exp Opin Drug Deliv 3:379–94
   PubMed Web of Science ®Google Scholar
• Sheppard Jr NF Santini Jr JT, Herman SJ, et al. MicroCHIPS Inc., assignee. (2007). Microchip Reservoir devices using wireless transmission of power and data. US Patent US7226442 B2, 5 June 2007
   Google Scholar
• Siegel RA, Rathbone MJ. (2012).Overview of controlled release mechanisms (Chapter 2). In: Siepmann J, Siegel RA, Rathbone MJ, eds. Advances in delivery science and technology: fundamentals and applications of controlled release drug delivery. New York, USA: Springer, 19–43
   Google Scholar
• Smith S, Tang TB, Terry JG, et al. (2007). Development of a miniaturised drug delivery system with wireless power transfer and communication. IET Nanobiotech 1:80–6
   Google Scholar
• Staples M. (2010). Microchips and controlled-release drug reservoirs. WIREs Nanomed Nanobiotech 2:400–17
   PubMed Web of Science ®Google Scholar
• Staples M, Daniel K, Cima MJ, Langer R (2006). Application of micro and nano-electromechanical devices to drug delivery. Pharma Res 23:847–63
   Web of Science ®Google Scholar
• Stevenson CL, Santini JT Jr, Langer R. (2012). Reservoir-based drug delivery systems utilizing microtechnology. Adv Drug Deliv Rev 64:1590–602
   PubMed Web of Science ®Google Scholar
• Tao SL, Desai TA. (2003). Microfabricated drug delivery systems: from particles to pores. Adv Drug Deliv Rev 55:315–28
   PubMed Web of Science ®Google Scholar
• Uhrich KE, Cannizzaro SM, Langer RS. (1999). Polymeric systems for controlled drug release. Chem Rev 99:3181–98
   PubMed Web of Science ®Google Scholar
• Urquhart J, Fara JW, Willis KL. (1984). Rate-controlled delivery systems in drug and hormone research. Ann Rev Pharmacol Toxicol 24:199–236
   PubMed Web of Science ®Google Scholar
• Vogelhuber W, Rotunno P, Magni E, et al. (2001). Programmable biodegradable implants. J Control Release 73:75–88
   PubMed Web of Science ®Google Scholar
• Voldman J, Gray ML, Schmidt MA. (1999). Microfabrication in biology and medicine. Annu Rev Biomed Eng 1:401–25
   PubMed Web of Science ®Google Scholar
• Watson J. (2012). Reengineering device translation timelines. Sci Trans Med 4:1–2
   Web of Science ®Google Scholar
• Webb EC. (2004). Chip shots: implanted semiconductors will allow drugs to be delivered exactly when and where they are needed. IEEE Spectrum 41:49–53
   Web of Science ®Google Scholar
• Wolf S, Tauber RN. (1986). Silicon: single-crystal growth & wafer preparation (Chapter 1). In: Wolf S, Tauber RN, eds. Silicon processing for the VLSI Era, Vol. 1: Process technology. California: Lattice Press, 22–31
   Google Scholar
• Ziaie B, Baldi A, Lei M, et al. (2004). Hard and soft micromachining for BioMEMS: review of techniques and examples of applications in microfluidics and drug delivery. Adv Drug Deliv Rev 56:145–72
   PubMed Web of Science ®Google Scholar