Drug Delivery, Volume 23, Issue 1 (2016)

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Drug Delivery, Volume 23, Issue 1 (2016)

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Review Article

Review
Implantable microchip: the futuristic controlled drug delivery system
Kumar Bishwajit Sutradhar & Chandra Datta Sumi
Pages: 1-11
Published online: 24 Apr 2014
AbstractforImplantable microchip: the futuristic controlled drug delivery system | Full Text | References | PDF (1.7 MB)
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Critical Review

Review
Recent advances of starch-based excipients used in extended-release tablets: a review
Yan Hong, Guodong Liu & Zhengbiao Gu
Pages: 12-20
Published online: 15 May 2014
AbstractforRecent advances of starch-based excipients used in extended-release tablets: a review | Full Text | References | PDF (1.4 MB)
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Review
Potential of targeted drug delivery system for the treatment of bone metastasis
Raichur Vinay & V. KusumDevi
Pages: 21-29
Published online: 19 May 2014
AbstractforPotential of targeted drug delivery system for the treatment of bone metastasis | Full Text | References | PDF (144.3 KB)
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Research Article

Article
Development of drug-loaded chitosan–vanillin nanoparticles and its cytotoxicity against HT-29 cells
Pu-Wang Li, Guang Wang, Zi-Ming Yang, Wei Duan, Zheng Peng, Ling-Xue Kong & Qing-Huang Wang
Pages: 30-35
Published online: 09 Apr 2014
AbstractforDevelopment of drug-loaded chitosan–vanillin nanoparticles and its cytotoxicity against HT-29 cells | Full Text | References | PDF (1.1 MB)
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Article
Design of solid lipid nanoparticles for caffeine topical administration
Carmelo Puglia, Alessia Offerta, Giorgia Giusy Tirendi, Maria Stella Tarico, Sergio Curreri, Francesco Bonina & Rosario Emanuele Perrotta
Pages: 36-40
Published online: 15 Apr 2014
AbstractforDesign of solid lipid nanoparticles for caffeine topical administration | Full Text | References | PDF (196.2 KB)
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Article
Enhanced dissolution and oral bioavailability of valsartan solid dispersions prepared by a freeze-drying technique using hydrophilic polymers
Wei-Juan Xu, Hong-Juan Xie, Qing-Ri Cao, Li-Li Shi, Yue Cao, Xiao-Yin Zhu & Jing-Hao Cui
Pages: 41-48
Published online: 15 Apr 2014
AbstractforEnhanced dissolution and oral bioavailability of valsartan solid dispersions prepared by a freeze-drying technique using hydrophilic polymers | Full Text | References | PDF (964.6 KB) | Supplemental
  • 5109 Views
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Article
Enhanced delivery of gentamicin to infection foci due to Staphylococcus aureus using gold nanorods
Mojtaba Salouti, Zahra Heidari, Azam Ahangari & Somayeh Zare
Pages: 49-54
Published online: 24 Apr 2014
AbstractforEnhanced delivery of gentamicin to infection foci due to Staphylococcus aureus using gold nanorods | Full Text | References | PDF (770.8 KB)
  • 1959 Views
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Article
pH triggered delivery of curcumin from Eudragit-coated chitosan microspheres for inflammatory bowel disease: characterization and pharmacodynamic evaluation
Rashmi Sareen, Nitin Jain, Ananya Rajkumari & K. L. Dhar
Pages: 55-62
Published online: 24 Apr 2014
AbstractforpH triggered delivery of curcumin from Eudragit-coated chitosan microspheres for inflammatory bowel disease: characterization and pharmacodynamic evaluation | Full Text | References | PDF (1.4 MB)
  • 5939 Views
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Article
Thermosensitive PEG–PCL–PEG (PECE) hydrogel as an in situ gelling system for ocular drug delivery of diclofenac sodium
Zichao Luo, Ling Jin, Lu Xu, Zhao Liang Zhang, Jing Yu, Shuai Shi, Xingyi Li & Hao Chen
Pages: 63-68
Published online: 24 Apr 2014
AbstractforThermosensitive PEG–PCL–PEG (PECE) hydrogel as an in situ gelling system for ocular drug delivery of diclofenac sodium | Full Text | References | PDF (820.1 KB) | Supplemental
  • 7594 Views
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Article
Pharmacokinetics and anti-hypertensive effect of metoprolol tartrate rectal delivery system
Amal El Sayeh F. Abou el Ela, Ayat A. Allam & Ehsan H. Ibrahim
Pages: 69-78
Published online: 24 Apr 2014
AbstractforPharmacokinetics and anti-hypertensive effect of metoprolol tartrate rectal delivery system | Full Text | References | PDF (465.6 KB)
  • 9847 Views
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Article
Preparation, in vitro and in vivo evaluation of bexarotene nanocrystals with surface modification by folate-chitosan conjugates
Li Li, Yu Liu, Jinjing Wang, Lijiang Chen, Wenjun Zhang & Xichen Yan
Pages: 79-87
Published online: 30 Apr 2014
AbstractforPreparation, in vitro and in vivo evaluation of bexarotene nanocrystals with surface modification by folate-chitosan conjugates | Full Text | References | PDF (1,015.1 KB)
  • 3252 Views
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Article
Bleomycin A6-loaded anionic liposomes with in situ gel as a new antitumoral drug delivery system
Weiming Ding, Yanfang Li, Xucheng Hou & Guiling Li
Pages: 88-94
Published online: 20 May 2014
AbstractforBleomycin A6-loaded anionic liposomes with in situ gel as a new antitumoral drug delivery system | Full Text | References | PDF (730.4 KB) | Supplemental
  • 3091 Views
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Article
PEGylation alleviates the non-specific toxicities of Alpha-Momorcharin and preserves its antitumor efficacy in vivo
Nian-hua Deng, Ling Wang, Qian-chuan He, Jue-cun Zheng, Yao Meng, Yan-Fa Meng, Chong-Jie Zhang & Fu-bing Shen
Pages: 95-100
Published online: 30 Apr 2014
AbstractforPEGylation alleviates the non-specific toxicities of Alpha-Momorcharin and preserves its antitumor efficacy in vivo | Full Text | References | PDF (421.6 KB)
  • 1815 Views
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Article
Baclofen novel gastroretentive extended release gellan gum superporous hydrogel hybrid system: in vitro and in vivo evaluation
Ibrahim A. El-said, Ahmed A. Aboelwafa, Rawia M. Khalil & Omaima N. ElGazayerly
Pages: 101-112
Published online: 30 Apr 2014
AbstractforBaclofen novel gastroretentive extended release gellan gum superporous hydrogel hybrid system: in vitro and in vivo evaluation | Full Text | References | PDF (1.7 MB)
  • 3831 Views
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Article
Effect of polydimethylsiloxane and ethylcellulose on in vitro permeation of centchroman from its transdermal patches
Varsha Gupta, Swati Singh, Madhumita Srivarstava, Hafsa Ahmad, Shakti Deep Pachauri, Kiran Khandelwal, Pankaj Dwivedi, Anil Kumar Dwivedi & CDRI communication no: 8635
Pages: 113-122
Published online: 30 Apr 2014
AbstractforEffect of polydimethylsiloxane and ethylcellulose on in vitro permeation of centchroman from its transdermal patches | Full Text | References | PDF (1.1 MB)
  • 2359 Views
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Article
Development of artemether and lumefantrine co-loaded nanostructured lipid carriers: physicochemical characterization and in vivo antimalarial activity
Deepa Parashar, Aditya N. P.Murthy R. S. R.
Pages: 123-129
Published online: 30 Apr 2014
AbstractforDevelopment of artemether and lumefantrine co-loaded nanostructured lipid carriers: physicochemical characterization and in vivo antimalarial activity | Full Text | References | PDF (299 KB)
  • 5927 Views
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Article
Brain targeted nanoparticulate drug delivery system of rasagiline via intranasal route
Deepti Mittal, Shadab Md, Quamrul Hasan, Mohammad Fazil, Asgar Ali, Sanjula Baboota & Javed Ali
Pages: 130-139
Published online: 30 Apr 2014
AbstractforBrain targeted nanoparticulate drug delivery system of rasagiline via intranasal route | Full Text | References | PDF (1.2 MB)
  • 6586 Views
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Article
Lactobionic acid coupled liposomes: an innovative strategy for targeting hepatocellular carcinoma
Divya Bansal, Kamini Yadav, Vikas Pandey, Aditya Ganeshpurkar, Abhishek Agnihotri & Nazneen Dubey
Pages: 140-146
Published online: 30 Apr 2014
AbstractforLactobionic acid coupled liposomes: an innovative strategy for targeting hepatocellular carcinoma | Full Text | References | PDF (335.3 KB)
  • 3703 Views
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Article
Effects of lipid vehicle and P-glycoprotein inhibition on the mesenteric lymphatic transport of paclitaxel in unconscious, lymph duct-cannulated rats
Qingqing Cai, Xinxian Deng, Zhongdong Li, Dianyun An, Teng Shen & Mingkang Zhong
Pages: 147-153
Published online: 30 Apr 2014
AbstractforEffects of lipid vehicle and P-glycoprotein inhibition on the mesenteric lymphatic transport of paclitaxel in unconscious, lymph duct-cannulated rats | Full Text | References | PDF (530.5 KB)
  • 2897 Views
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Article
Formulation development of novel in situ nanoemulgel (NEG) of ketoprofen for the treatment of periodontitis
M. Srivastava, K. Kohli & M. Ali
Pages: 154-166
Published online: 30 Apr 2014
AbstractforFormulation development of novel in situ nanoemulgel (NEG) of ketoprofen for the treatment of periodontitis | Full Text | References | PDF (1.1 MB)
  • 7287 Views
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Article
A novel implantable catheter system with transcutaneous port for intermittent convection-enhanced delivery of carboplatin for recurrent glioblastoma
Neil U. Barua, Kirsten Hopkins, Max Woolley, Stephen O’Sullivan, Rob Harrison, Richard J. Edwards, Alison S. Bienemann, Marcella J. Wyatt, Azeem Arshad & Steven S. Gill
Pages: 167-173
Published online: 02 May 2014
AbstractforA novel implantable catheter system with transcutaneous port for intermittent convection-enhanced delivery of carboplatin for recurrent glioblastoma | Full Text | References | PDF (2 MB)
  • 5282 Views
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Article
Assessment of the drug loading, in vitro and in vivo release behavior of novel pH-sensitive hydrogel
Kai Dong, Yalin Dong, Cuiyu You, Wei Xu, Xiaoyan Huang, Yan Yan, Lu Zhang, Ke Wang & Jianfeng Xing
Pages: 174-184
Published online: 07 May 2014
AbstractforAssessment of the drug loading, in vitro and in vivo release behavior of novel pH-sensitive hydrogel | Full Text | References | PDF (1.4 MB)
  • 8005 Views
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Article
Mucoadhesive glycol chitosan nanoparticles for intranasal delivery of hepatitis B vaccine: enhancement of mucosal and systemic immune response
Dilip Pawar & K.S. Jaganathan
Pages: 185-194
Published online: 14 May 2014
AbstractforMucoadhesive glycol chitosan nanoparticles for intranasal delivery of hepatitis B vaccine: enhancement of mucosal and systemic immune response | Full Text | References | PDF (2 MB)
  • 5261 Views
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Article
Badam gum: a natural polymer in mucoadhesive drug delivery. Design, optimization, and biopharmaceutical evaluation of badam gum-based metoprolol succinate buccoadhesive tablets
Chaithanya Krishna Mylangam, Sudhakar Beeravelli, Jyothi Medikonda, Jagannadha Subrahmanyam Pidaparthi & Venkata Ramana Murthy Kolapalli
Pages: 195-206
Published online: 14 May 2014
AbstractforBadam gum: a natural polymer in mucoadhesive drug delivery. Design, optimization, and biopharmaceutical evaluation of badam gum-based metoprolol succinate buccoadhesive tablets | Full Text | References | PDF (1.2 MB)
  • 6283 Views
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Article
Microemulsion-based drug delivery system for transnasal delivery of Carbamazepine: preliminary brain-targeting study
Rashmin Bharatbhai Patel, Mrunali Rashmin Patel, Kashyap K. Bhatt, Bharat G. Patel & Rajiv V. Gaikwad
Pages: 207-213
Published online: 14 May 2014
AbstractforMicroemulsion-based drug delivery system for transnasal delivery of Carbamazepine: preliminary brain-targeting study | Full Text | References | PDF (348.1 KB)
  • 4385 Views
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Article
Curcumin-loaded lipid nanocarrier for improving bioavailability, stability and cytotoxicity against malignant glioma cells
Anil Kumar, Alka Ahuja, Javed Ali & Sanjula Baboota
Pages: 214-229
Published online: 14 May 2014
AbstractforCurcumin-loaded lipid nanocarrier for improving bioavailability, stability and cytotoxicity against malignant glioma cells | Full Text | References | PDF (755.3 KB)
  • 5894 Views
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Article
Solubilized delivery of paliperidone palmitate by d-alpha-tocopheryl polyethylene glycol 1000 succinate micelles for improved short-term psychotic management
Madaswamy S. Muthu, Ashish K. Sahu, Sonali, Allabakshi Abdulla, Dhansukh Kaklotar, Chellappa V. Rajesh, Sanjay Singh & Bajarangprasad L. Pandey
Pages: 230-237
Published online: 22 May 2014
AbstractforSolubilized delivery of paliperidone palmitate by d-alpha-tocopheryl polyethylene glycol 1000 succinate micelles for improved short-term psychotic management | Full Text | References | PDF (1.1 MB)
  • 3597 Views
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Article
pH-responsive thiolated chitosan nanoparticles for oral low-molecular weight heparin delivery: in vitro and in vivo evaluation
Bo Fan, Yang Xing, Ying Zheng, Chuan Sun & Guixian Liang
Pages: 238-247
Published online: 28 May 2014
AbstractforpH-responsive thiolated chitosan nanoparticles for oral low-molecular weight heparin delivery: in vitro and in vivo evaluation | Full Text | References | PDF (810.1 KB)
  • 5377 Views
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Article
Enhanced oral bioavailability of salmeterol by loaded PLGA microspheres: preparation, in vitro, and in vivo evaluation
Haiping Zhang & Jianfang Xu
Pages: 248-253
Published online: 14 May 2014
AbstractforEnhanced oral bioavailability of salmeterol by loaded PLGA microspheres: preparation, in vitro, and in vivo evaluation | Full Text | References | PDF (348.2 KB)
  • 2931 Views
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Article
Evaluation of polyamidoamine dendrimers as potential carriers for quercetin, a versatile flavonoid
Kanika Madaan, Viney Lather & Deepti Pandita
Pages: 254-262
Published online: 20 May 2014
AbstractforEvaluation of polyamidoamine dendrimers as potential carriers for quercetin, a versatile flavonoid | Full Text | References | PDF (756.2 KB)
  • 5033 Views
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Article
Microdialysis pharmacokinetic study of scopolamine in plasma, olfactory bulb and vestibule after intranasal administration
Yan Wei, Mingzhen Ying, Shuai Xu, Feng Wang, Aifeng Zou, Shilei Cao, Xinguo Jiang & Yajie Wang
Pages: 263-268
Published online: 28 May 2014
AbstractforMicrodialysis pharmacokinetic study of scopolamine in plasma, olfactory bulb and vestibule after intranasal administration | Full Text | References | PDF (457.5 KB)
  • 3075 Views
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Article
Preparation of surface multiple-coated polylactide acid drug-loaded nanoparticles for intranasal delivery and evaluation on its brain-targeting efficiency
Junjie Bian, Zhixiang Yuan, Xiaoliang Chen, Yuan Gao, Chaoqun Xu & Jianyou Shi
Pages: 269-276
Published online: 20 May 2014
AbstractforPreparation of surface multiple-coated polylactide acid drug-loaded nanoparticles for intranasal delivery and evaluation on its brain-targeting efficiency | Full Text | References | PDF (883.9 KB)
  • 1654 Views
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Article
Hydroxyethyl starch–10-hydroxy camptothecin conjugate: synthesis, pharmacokinetics, cytotoxicity and pharmacodynamics research
Guofei Li, Cuifang Cai, Yingjie Qi & Xing Tang
Pages: 277-284
Published online: 15 May 2014
AbstractforHydroxyethyl starch–10-hydroxy camptothecin conjugate: synthesis, pharmacokinetics, cytotoxicity and pharmacodynamics research | Full Text | References | PDF (428.3 KB) | Supplemental
  • 2090 Views
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Article
Comparison of active and passive targeting of doxorubicin for somatostatin receptor 2 positive tumor models by octreotide-modified HPMA copolymer-doxorubicin conjugates
Shuang He, Zhou Zhou, Lian Li, Qingqing Yang, Yang Yang, Shan Guan, Jian Zhang, Xi Zhu, Yun Jin & Yuan Huang
Pages: 285-296
Published online: 28 May 2014
AbstractforComparison of active and passive targeting of doxorubicin for somatostatin receptor 2 positive tumor models by octreotide-modified HPMA copolymer-doxorubicin conjugates | Full Text | References | PDF (1.8 MB)
  • 3787 Views
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Article
Effervescent tablet formulation for enhanced patient compliance and the therapeutic effect of risperidone
Kareem Abu Bakr Mohammed, Howida Kamal Ibrahim & Mahmoud Mohammed Ghorab
Pages: 297-306
Published online: 15 May 2014
AbstractforEffervescent tablet formulation for enhanced patient compliance and the therapeutic effect of risperidone | Full Text | References | PDF (732.8 KB)
  • 12741 Views
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Article
Evaluation of brain targeting efficiency of intranasal microemulsion containing olanzapine: pharmacodynamic and pharmacokinetic consideration
Rashmin B. Patel, Mrunali R. Patel, Kashyap K. Bhatt, Bharat G. Patel & Rajiv V. Gaikwad
Pages: 307-315
Published online: 20 May 2014
AbstractforEvaluation of brain targeting efficiency of intranasal microemulsion containing olanzapine: pharmacodynamic and pharmacokinetic consideration | Full Text | References | PDF (438.6 KB)
  • 3483 Views
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Article
High drug load, stable, manufacturable and bioavailable fenofibrate formulations in mesoporous silica: a comparison of spray drying versus solvent impregnation methods
Shiqi Hong, Shoucang Shen, David Cheng Thiam Tan, Wai Kiong Ng, Xueming Liu, Leonard S. O. Chia, Anastasia W. Irwan, Reginald Tan, Steven A Nowak, Kennan Marsh & Rajeev Gokhale
Pages: 316-327
Published online: 22 May 2014
AbstractforHigh drug load, stable, manufacturable and bioavailable fenofibrate formulations in mesoporous silica: a comparison of spray drying versus solvent impregnation methods | Full Text | References | PDF (3.3 MB)
  • 6137 Views
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Article
Eudragit-coated dextran microspheres of 5-fluorouracil for site-specific delivery to colon
Gopal Rai, Awesh K. Yadav, Narendra K. Jain & Govind P. Agrawal
Pages: 328-337
Published online: 20 May 2014
AbstractforEudragit-coated dextran microspheres of 5-fluorouracil for site-specific delivery to colon | Full Text | References | PDF (605.9 KB)
  • 3937 Views
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Article
Effect of microemulsion in topical sertaconazole hydrogel: in vitro and in vivo study
Susijit Sahoo, Nihar Ranjan Pani & Sunit Kumar Sahoo
Pages: 338-345
Published online: 20 May 2014
AbstractforEffect of microemulsion in topical sertaconazole hydrogel: in vitro and in vivo study | Full Text | References | PDF (503.4 KB)
  • 3709 Views
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Article
Paliperidone microemulsion for nose-to-brain targeted drug delivery system: pharmacodynamic and pharmacokinetic evaluation
Mrunali R. Patel, Rashmin B. Patel, Kashyap K. Bhatt, Bharat G. Patel & Rajiv V. Gaikwad
Pages: 346-354
Published online: 28 May 2014
AbstractforPaliperidone microemulsion for nose-to-brain targeted drug delivery system: pharmacodynamic and pharmacokinetic evaluation | Full Text | References | PDF (406.3 KB)
  • 4710 Views
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Article
Optimized sildenafil citrate fast orodissolvable film: a promising formula for overcoming the barriers hindering erectile dysfunction treatment
Khaled Mohamed Hosny, Khalid Mohamed El-say & Osama Abdelhakim Ahmed
Pages: 355-361
Published online: 28 May 2014
AbstractforOptimized sildenafil citrate fast orodissolvable film: a promising formula for overcoming the barriers hindering erectile dysfunction treatment | Full Text | References | PDF (445.7 KB)
  • 14485 Views
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