3,688
Views
39
CrossRef citations to date
0
Altmetric
Research Article

Formulation development of novel in situ nanoemulgel (NEG) of ketoprofen for the treatment of periodontitis

, &
Pages 154-166 | Received 18 Feb 2014, Accepted 20 Mar 2014, Published online: 30 Apr 2014

References

  • Ahmed M, Ramadan W, Rambhu D, Shakeel F. (2008). Potential of nanoemulsions for intravenous delivery of rifampicin. Pharmazie 63:806–11
  • Bali V, Ali M, Ali J. (2010). Study of surfactant combinations and development of a novel nanoemulsion for minimising variations in bioavailability of ezetimibe. Coll Surf B Biointerface 76:410–20
  • Blaszyk M, Holley RA. (1998). Interaction of monolaurin, eugenol and sodium citrate on growth of common meat spoilage and pathogenic organisms. Int J Food Microbiol 39:175–83
  • Bowen WH, Pearson SK, Jerussi TP. (2000). Influence of (S)-ketoprofen and fluoride on caries in rats. Oral Dis 6:12–14
  • Bruschi ML, Jones DS, Panzeri H, et al. (2007). Semisolid systems containing propolis for the treatment of periodontal disease: in vitro release kinetics, syringeability, rheological, textural, and mucoadhesive properties. J Pharm Sci 96:2074–89
  • Chopra S, Pati GV, Motwani SK. (2007). Release modulating hydrophilic matrix systems of losartan potassium: optimisation of formulation using statistical experimental design. Eur J Pharm Biopharm 66:73–82
  • Dahl JE. (2007). Potential of dental adhesives to induce mucosal irritation evaluated by the HET-CAM method. Acta Odontol Scand 65:275–83
  • Friedman M, Henika PR, Mandrell RE. (2002). Bactericidal activities of plant essential oils and some of their isolated constituents against Campylobacter jejuni, Escherichia coli, Listeria monocytogenes and Salmonella enterica. J Food Prot 65:1545–60
  • Gill AO, Holley RA. (2006). Inhibition of membrane bound ATPases of Escherichia coli and Listeria monocyto-genes by plant oil aromatics. Int J Food Microbiol 111:170–4
  • Gilleron L, Coecke S, Sysmans M, et al. (1996). Evaluation of a modified HET-CAM assay as a screening test for eye irritancy. Toxicol In Vitro 10:431–46
  • Govender S, Pillay V, Chetty DJ, et al. (2005). Optimisation and characterisation of bioadhesive controlled release tetracycline microspheres. Int J Pharm 306:24–40
  • Hamouda T, Hayes MM, Cao Z, et al. (1999). A novel surfactant nanoemulsion with broad spectrum sporicidal activity against bacillus species. J Infect Dis 180:1939–49
  • Howell TH 1993. Blocking periodontal disease progression with anti-inflammatory agents. J Periodontol 64:828–33
  • Javed S, Kohli K. (2010). Local delivery of minocycline: a therapeutic paradigm in periodontal diseases. Curr Drug Deliv 7:398–406
  • Jones DS, Woolfson AD, Djokic J, Coulter WA. (1996). Development and mechanical characterization of bioadhesive semisolid, polymeric systems containing tetracycline for the treatment of periodontal diseases. Pharm Res 13:1734–8
  • Kumari N, Pathak K. (2012). Dual controlled release, in situ gelling periodontal sol of metronidazole benzoate and serratiopeptidase: statistical optimization and mechanistic evaluation. Curr Drug Deliv 9:74–84
  • Korsmeyer RW, Gurny R, Doelker EM, et al. (1983). Mechanism of solute release from porous hydrophilic polymers. Int J Pharm 15:25–35
  • Lawrence HP, Paquette DW, Smith PC, et al. (1998). Pharmacokinetic and safety evaluations of ketoprofen gels in subjects with adult periodontitis. J Dent Res 77:1904–12
  • Lee VA, Karthikeyan R, Rawls HR, Amaechi BT. (2010). Anticariogenic effect of a cetylpyridinium chloride containing nanoemulsion. J Dent 38:742–9
  • Li KL, Vogel R, Jeffcoat MK, et al. (1996). The effect of ketoprofen creams on periodontal disease in rhesus monkeys. J Periodontal Res 31:525–32
  • Luepke NP. (1985). Hen’s egg chorioallantoic membrane for irritation potential. Food Chem Toxicol 23:287–91
  • Offenbacher S, Odle BM, Green MD, et al. (1990). Inhibition of human periodontal prostaglandin E2 synthesis with selected agents. Agents Actions 29:232–8
  • Paquette DW, Fiorellini JP, Martuscelli G. (1997). Enantiospecific inhibition of ligature induced periodontitis in beagles with topical (S)-ketoprofen. J Clin Periodontol 24:521–8
  • Pauletto N, Silver JG, Larjava H. (1997). Nonsteroidal anti-inflammatory agents: potential modifiers of periodontal disease progression. J Can Dent Assoc 63:824–9
  • Philip AK, Srivastava M, Pathak K. (2009). Buccoadhesive gels of glibenclamide: a means for achieving enhanced bioavailability. Drug Del 16:405–15
  • Rhee YS, Chang SY, Park CW, et al. (2008). Optimization of ibuprofen gel formulations using experimental design technique for enhanced transdermal penetration. Int J Pharm 364:14–20
  • Shafiq S, Shakeel F, Talegaonkar S, et al. (2007). Formulation development and optimization using nanoemulsion technique: a technical note. AAPS PharmSciTech 8(2):E12–E17
  • Sharma S, Kumar A, Sahni JK, et al. (2012). Nanoemulsion based hydrogel containing omega 3 fatty acids as a surrogate of betamethasone dipropionate for topical delivery. Adv Sci Lett 6:221–31
  • Shirsand S, Para M, Nagendrakumar D, et al. (2012). Formulation and evaluation of Ketoconazole niosomal gel drug delivery system. Int J Pharm Investig 2: 201–7
  • Srinivas M, Medaiah S, Girish S, et al. (2011). The effect of Ketoprofen in chronic periodontitis: a clinical double-blind study. J Indian Soc Periodontol 15:255–9
  • Vinardell MP, Mitjans M. (2006). The chorioallantoic membrane test as a model to predict the potential human eye irritation induced by commonly used laboratory solvents. Toxicol In Vitro 20:1066–70
  • Vyas SP, Sihorkar V, Mishra V. (2000). Controlled and targeted drug delivery strategies towards intraperiodontal pocket disease. J Clin Pharm Ther 25:21–42
  • Walsh SE, Maillard JY, Russell AD, et al. (2003). Activity and mechanisms of action of selected biocidal agents on Gram-positive and negative bacteria. J Appl Microbiol 94: 240–7

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.