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Research Article

Evaluation of brain targeting efficiency of intranasal microemulsion containing olanzapine: pharmacodynamic and pharmacokinetic consideration

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Pages 307-315 | Received 12 Mar 2014, Accepted 03 Apr 2014, Published online: 20 May 2014

References

  • Babbar AK, Singh AK, Goel HC, et al. (2000). Evaluation of 99mTc-labeled photosan-3, a hematoporphyrin derivative, as a potential radiopharmaceutical for tumor scintigraphy. Nucl Med Biol 27:419–26
  • Braso A, Princep M, Schmid M, et al. (2003). Developmental pharmacology: behavior assay in antipsychotics. Methods Find Expt Clin Pharmacol 25:1–2
  • Canuso CM, Youssef EA, Bossie CA, et al. (2008). Paliperidone extended-release tablets in schizophrenia patients previously treated with risperidone. Int Clin Psychopharm 23:209–15
  • Chow HS, Chen Z, Matsuura GT. (1999). Direct transport of cocaine from the nasal cavity to brain following intranasal cocaine administration in rats. J Pharm Sci 88:754–8
  • Eckelman WC. (1995). Radiolabeling with technetium-99m to study highcapacity and low-capacity biochemical systems. Eur J Nucl Med 22:249–63
  • Elshafeey AH, Bendas ER, Mohamed OH. (2009). Intranasal microemulsion of sildenafil citrate: in vitro evaluation and in vivo pharmacokinetic study in rabbits. AAPS PharmSciTech 10:361–4
  • Hiriyanna SG, Basavaiah K, Goud PSK, et al. (2008). Identification and characterization of olanzapine degradation products under oxidative stress conditions. Acta Chromatogr 20:81–93
  • Jogani VV, Shah PJ, Mishra P, et al. (2008). Intranasal mucoadhesive microemulsion of tacrine to improve brain targeting. Alzheimer Dis Assoc Disord 22:116–24
  • Kaur P, Kim K. (2008). Pharmacokinetics and brain uptake of diazepam after intravenous and intranasal administration in rats and rabbits. Int J Pharm 364:27–35
  • Kulkarni SK, Jisheph P. (1998). Psychopharmacological profile of sitone granules, A herbal drug preparation. Ind drug 35:536–44
  • Kumar M, Misra A, Mishra AK, et al. (2008a). Mucoadhesive nanoemulsion-based intranasal drug delivery system of olanzapine for brain targeting. J Brain Targ 16:806–14
  • Kumar M, Misra A, Babbar AK, et al. (2008b). Intranasal nanoemulsion based brain targeting drug delivery system of risperidone. Int J Pharm 358:285–91
  • Le M, Simon H. (1991). Mesocorticolimbic dopaminergic network functional and regulatory roles. Physiol Rev 71:155–234
  • Li L, Nandi I, Kim KH. (2002). Development of an ethyl laurate-based microemulsion for rapid-onset intranasal delivery of diazepam. Int J Pharm 237:77–85
  • Nasrallah HA, Targum SD, Tandon R, et al. (2005). Defining and measuring clinical effectiveness in the treatment of schizophrenia. Psychiatr Serv 56:273–82
  • Patel RB, Patel MR, Bhatt KK, Patel BG. (2013a). Formaulation and evaluation of microemulsion based drug delivery system for intranasal administration of olanzapine. Int J Bimed Pharm Sci 7:20–7
  • Patel RB, Patel MR, Bhatt KK, et al. (2013b). Risperidone microemulsion for transnasal delivery: pharmacodynamic and pharmacokinetic evaluation. Pharm Nanotech 1:44–53
  • Patel RB, Patel MR, Bhatt KK, Patel BG. (2013c). Paliperidone loaded mucoadhesive microemulsion in treatment of schizophrenia: formulation consideration. J Pharm Inn 8:195–204
  • Patel RB, Patel MR, Bhatt KK, Patel BG. (2010). Development and validation of an HPTLC method for determination of olanzapine in formulations. J AOAC Int 93:811–9
  • Porecha S, Shah T, Jogani V, et al. (2009). Microemulsion based intranasal delivery system for treatment of insomnia. Drug Del 16:128–34
  • Salamone JD, Correa M, Mingote SM, Weber SM. (2005). Beyond the reward hypothesis: alternative functions of nucleus accumbens dopamine. Curr Opin Pharmacol 5:34–41
  • Sharma G, Mishra AK, Mishra P, Misra A. (2009). Intranasal cabergoline: pharmacokinetic and pharmacodynamic studies. AAPS PharmSciTech 10:1321–30
  • Shibuya TT, Nishimori MH. (1982). Behavioural pharmacological studies in the monkey with DD-3480. Int J Clin Pharmaco Ther Toxicol 20:251–4
  • Shinde RL, Jindal AB, Devarajan PV. (2011). Micromeulsions and nanoemulsions for targeted drug delivery to the brain. Current Nanosci 7:119–33
  • Vyas TK, Babbar AK, Sharma RK, Misra A. (2005). Intranasal mucoadhesive microemulsion of zolmitriptan: preliminary studies on brain targeting. J Drug Target 13:317–24
  • Vyas TK, Babbar AK, Sharma RK, et al. (2006a). Intranasal mucoadhesive microemulsions of clonazepam: preliminary studies on brain targeting. J Pharm Sci 95:570–80
  • Vyas TK, Babbar AK, Sharma RK, et al. (2006b). Preliminary brain targeting studies of intranasal mucoadhesive microemulsions of sumatriptan. AAPS PharmSci Tech 7:E49–57
  • Zacher JL, Grady SE. (2007). Paliperidone extended-release tablets (Invega). Psychopharma Rev 42:51–8
  • Zhang Q, Jiang X, Jiang W, et al. (2004). Preparation of nimodipine-loaded microemulsion for intranasal delivery and evaluation on the targeting efficiency to the brain. Int J Pharm 275:85–96

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