Atazanavir-loaded Eudragit RL 100 nanoparticles to improve oral bioavailability: optimization and in vitro/in vivo appraisal

References

• Al-Qadi S, Grenha A, Carrión-Recio D, et al. (2012). Microencapsulated chitosan nanoparticles for pulmonary protein delivery: in vivo evaluation of insulin-loaded formulations. J Control Release 157:383–90
   PubMed Web of Science ®Google Scholar
• Baba K, Tanaka Y, Kubota A, et al. (2011). A method for enhancing the ocular penetration of eye drops using nanoparticles of hydrolysable dye. J Control Release 153:278–87
   PubMed Web of Science ®Google Scholar
• Balkundi S, Nowacek AS, Veerubhotla RS, et al. (2011). Comparative manufacture and cell based delivery of antiretroviral nano formulations. Int J Nanomedicine 6:3393–404
   PubMed Web of Science ®Google Scholar
• Beloqui A, Solinís MA, Gascón AR, et al. (2013). Mechanism of transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier. J Control Release 166:115–23
   PubMed Web of Science ®Google Scholar
• Bender AR, Von Briesen H, Kreuter J, Duncan IB, Rubsamen-Waigmann H. (1996). Efficiency of nanoparticles as a carrier system for antiviral agents in human immunodeficiency virus-infected human monocytes/macrophages in vitro. Antimicrob Agents Chemother 4:1467–71
   Google Scholar
• Benet LZ, Broccatelli F, Oprea TI. (2011). BDDCS applied to over 900 drugs. AAPS J 13:519–47
   PubMed Web of Science ®Google Scholar
• Dahan A, Hoffman A. (2007). The effect of different lipid based formulations on the oral absorption of lipophilic drugs: the ability of in vitro lipolysis and consecutive ex vivo intestinal permeability data to predict in vivo bioavailability in rats. Eur J Pharm Biopharm 67:96–105
   PubMed Web of Science ®Google Scholar
• Dodiya SS, Chavhan SS, Sawant KK, Korde AG. (2011). Solid lipid nanoparticles and nanosuspension formulation of Saquinavir: preparation, characterization, pharmacokinetics and biodistribution studies. J Microencapsul 28:515–27
   PubMed Web of Science ®Google Scholar
• Devi KV, Pai RS. (2006). Antiretrovirals: need for an effective drug delivery. Indian J Pharm Sci 68:1–6
   Google Scholar
• Ensign LM, Cone R, Hanes J. (2012). Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers. Adv Drug Deliv Rev 64:557–70
   PubMed Web of Science ®Google Scholar
• Fagerholm U, Johansson M, Lennernas H. (1996). Comparison between permeability coefficients in rat and human jejunum. Pharm Res 13:1336–42
   PubMed Web of Science ®Google Scholar
• Fukushima K, Terasaka S, Haraya K, et al. (2007). Pharmaceutical approach to HIV protease inhibitor atazanavir for bioavailability enhancement based on solid dispersion system. Biol Pharm Bull 30:733–8
   PubMed Web of Science ®Google Scholar
• Gao F, Zhang Z, Bu H, et al. (2011). Nanoemulsion improves the oral absorption of candesartan cilexetil in rats: performance and mechanism. J Control Release 149:168–74
   PubMed Web of Science ®Google Scholar
• Ho YF, Lai MY, Yu HY, et al. (2008). Application of rat in situ single-pass intestinal perfusion in the evaluation of presystemic extraction of indinavir under different perfusion rates. J Formos Med Assoc 107:37–45
   PubMed Web of Science ®Google Scholar
• Kawabata Y, Wada K, Nakatani M, et al. (2011). Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: basic approaches and practical applications. Int J Pharm 420:1–10
   PubMed Web of Science ®Google Scholar
• Lu Y, Kim S, Park K. (2011). In vitro–in vivo correlation: Perspectives on model development. Int J Pharm 418:142–148
   PubMed Web of Science ®Google Scholar
• Mastan SK, Kumar K (2010). Influence of atazanavir on the pharmacodynamics and pharmacokinetics of gliclazide in animal models. Int J Diabetes Mellit 2:56–60
   Google Scholar
• Merisko-Liversidge EM, Liversidge GG. (2008). Drug nanoparticles: formulating poorly water-soluble compounds. Toxicol Pathol 36:43–8
   PubMed Web of Science ®Google Scholar
• Merisko-Liversidge EM, Liversidge GG. (2011). Nanosizing for oral and parenteral drug delivery: a perspective on formulating poorly-water soluble compounds using wet media milling technology. Adv. Drug Deliv Rev 63:427–40
   PubMed Web of Science ®Google Scholar
• Mora-Huertas CE, Fessi H, Elaissari A. (2010). Polymer-based nanocapsules for drug delivery. Int J Pharm 385:113–42
   PubMed Web of Science ®Google Scholar
• Norris DA, Puri N, Sinko PJ. (1998). The effect of physical barriers and properties on the oral absorption of particulates. Adv Drug Deliv Rev 34:135–54
   PubMed Web of Science ®Google Scholar
• Pongpaibul Y, Price JC, Whitworth CW. (1984). Preparation and evaluation of controlled release indomethacin microspheres. Drug Dev Ind Pharm 10:1597–616
   Web of Science ®Google Scholar
• Quevedo MA, Nieto LE, Brinon MC. (2011). P-glycoprotein limits the absorption of the anti-HIV drug zidovudine through rat intestinal segments. Eur J Pharm Sci 43:151–9
   PubMed Web of Science ®Google Scholar
• Shi J, Votruba AR, Farokhzad OC, Langer R. (2010). Nanotechnology in drug delivery and tissue engineering: from discovery to applications. Nano Lett 10:3223–30
   PubMed Web of Science ®Google Scholar
• Simpson KN, Jones WJ, Rajagopalan R, Dietz B. (2007). Cost effectiveness of lopinavir/ritonavir tablets compared with atazanavir plus ritonavir in antiretroviral-experienced patients in the UK, France, Italy and Spain. Clin Drug Investig 27:807–17
   PubMed Web of Science ®Google Scholar
• Singh G, Pai RS, Devi VK. (2012a). Optimization of pellets containing solid dispersion prepared by extrusion/spheronization using central composite design and desirability function. J Young Pharmacists 4:146–56
   PubMedGoogle Scholar
• Singh G, Pai RS, Devi VK. (2012b). Response surface methodology and process optimization of sustained release pellets using Taguchi orthogonal array design and central composite design. J Adv Pharm Tech Res 3:30–40
   PubMedGoogle Scholar
• Singh G, Pai RS. (2013). Pharmacokinetics and in vivo biodistribution of optimized PLGA nanoparticulate drug delivery system for controlled release of emtricitabine. Drug Deliv DOI: 10.3109/10717544.2013.867382.
   Web of Science ®Google Scholar
• Singh G, Pai RS (2014a). Optimized PLGA nanoparticle platform for orally dosed trans-resveratrol with enhanced bioavailability potential. Expert Opin Drug Deliv 11:647–59
   PubMed Web of Science ®Google Scholar
• Singh G, Pai RS (2014b). In-vitro/in-vivo characterization of trans-resveratrol-loaded nanoparticulate drug delivery system for oral administration. J Pharm Pharmacol Doi: 10.1111/jphp.12232.
   Web of Science ®Google Scholar
• Singh G, Pai RS (2014c). Optimized self-nanoemulsifying drug delivery system of atazanavir with enhanced oral bioavailability: in vitro/in vivo characterization. Expert Opin Drug Deliv Doi: 10.1517/17425247.2014.913566.
   Web of Science ®Google Scholar